DrLLPS - Data resource of LLPS

LLPS-Mal-0799
EIF1AX

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Uncharacterized protein
Gene Name:	EIF1AX
Ensembl Gene:	ENSMLEG00000031392.1
Ensembl Protein:	ENSMLEP00000014706.1
Organism:	Mandrillus leucophaeus
Taxa ID:	9568
LLPS Type:	LLPS regulator

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, P-body, Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Caenorhabditis elegans	LLPS-Cae-0095	Q9TXU7	Regulator	P-body	66.67	5e-44	151
Saccharomyces cerevisiae	LLPS-Sac-0477	P38912	Client	Stress granule	65.79	8e-49	161
Arabidopsis thaliana	LLPS-Art-0680	Q9SJB9	Client	Nucleolus	76.77	7e-50	164
Homo sapiens	LLPS-Hos-1400	P47813	Client	Nucleolus	100.00	1e-65	204

▼ FUNCTION

Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSMLET00000038157.1	ENSMLEP00000014706.1
Ensembl	ENSMLET00000038219.1	ENSMLEP00000014768.1
Ensembl	ENSMLET00000038165.1	ENSMLEP00000014714.1
Ensembl	ENSMLET00000038216.1	ENSMLEP00000014765.1
Ensembl	ENSMLET00000038151.1	ENSMLEP00000014700.1
UniProt		A0A2K5YGU6, A0A2K5YGU6_MANLE

▼ SEQUENCE

Protein Sequence (FASTA)
1 QPGRQSKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAM CFDGVKRLCH 60 61 IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT 120 121 FGPGDDDEIQ FDDIGDDDED IDDVSRCTLC FPIFVIIHGE TNFPLT 166
Nucleotide CDS Sequence (FASTA)
1 ATGCCCAAGA ATAAAGAGTA TGCTCAGGTA ATCAAAATGT TGGGAAATGG ACGGCTAGAA 60 61 GCAATGTGTT TTGATGGTGT AAAGAGGTTA TGTCACATCA GAGGAAAATT GAGAAAAAAG 120 121 GTTTGGATAA ATACCTCGGA CATTATATTG GTCGGTCTCC GAGACTACCA GGATAACAAA 180 181 GCTGATGTGA TTTTAAAATA CAATGCAGAT GAAGCTAGAA GTCTGAAGGC ATACGGCGAG 240 241 CTTCCAGAGC ATGCTAAAAT CAATGAAACT GATACATTTG GTCCTGGAGA TGATGATGAA 300 301 ATTCAGTTCG ATGACATCGG AGATGATGAT GAAGATATTG ATGACATCTA A 351

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0396	Initiation factor
KW-0648	Protein biosynthesis
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0003743	Molecular Function	Translation initiation factor activity

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Paa-1630	Papio anubis	100.0	4e-96	282
LLPS-Aim-1021	Ailuropoda melanoleuca	100.0	5e-80	240
LLPS-Mup-0404	Mustela putorius furo	100.0	6e-80	240
LLPS-Cea-0068	Cercocebus atys	100.0	3e-101	295
LLPS-Sah-0995	Sarcophilus harrisii	100.0	4e-80	241
LLPS-Mam-0146	Macaca mulatta	100.0	4e-96	282
LLPS-Xet-1865	Xenopus tropicalis	100.0	2e-71	219
LLPS-Pap-3088	Pan paniscus	100.0	2e-94	278
LLPS-Otg-3429	Otolemur garnettii	100.0	9e-80	240
LLPS-Ora-1159	Ornithorhynchus anatinus	99.15	1e-79	239
LLPS-Meg-0485	Meleagris gallopavo	99.15	2e-79	239
LLPS-Anp-0650	Anas platyrhynchos	99.15	2e-79	239
LLPS-Pes-1837	Pelodiscus sinensis	99.15	3e-79	238
LLPS-Maf-0083	Macaca fascicularis	98.51	2e-75	229
LLPS-Rhb-0307	Rhinopithecus bieti	98.51	5e-75	228
LLPS-Tag-0973	Taeniopygia guttata	98.11	2e-70	214
LLPS-Fia-0968	Ficedula albicollis	97.59	9e-54	172
LLPS-Bot-2068	Bos taurus	96.72	1e-80	242
LLPS-Scf-0274	Scleropages formosus	96.72	1e-80	242
LLPS-Ran-0159	Rattus norvegicus	96.72	1e-80	242
LLPS-Ova-1935	Ovis aries	96.72	1e-80	242
LLPS-Myl-1863	Myotis lucifugus	96.72	1e-80	242
LLPS-Mea-1599	Mesocricetus auratus	96.72	1e-80	242
LLPS-Mum-3487	Mus musculus	96.72	1e-80	242
LLPS-Chs-3218	Chlorocebus sabaeus	96.72	1e-80	242
LLPS-Sus-1229	Sus scrofa	96.72	6e-81	243
LLPS-Fud-0928	Fukomys damarensis	96.72	1e-80	242
LLPS-Caj-1011	Callithrix jacchus	96.72	1e-80	243
LLPS-Caf-0924	Canis familiaris	96.72	1e-80	242
LLPS-Poa-0294	Pongo abelii	96.72	1e-80	242
LLPS-Cap-0477	Cavia porcellus	96.72	1e-80	242
LLPS-Cas-2288	Carlito syrichta	96.72	1e-80	242
LLPS-Hos-1400	Homo sapiens	96.72	1e-80	242
LLPS-Fec-0909	Felis catus	96.72	1e-80	242
LLPS-Mod-0364	Monodelphis domestica	96.72	1e-80	242
LLPS-Gog-1375	Gorilla gorilla	96.33	9e-70	214
LLPS-Xim-0787	Xiphophorus maculatus	95.9	3e-80	241
LLPS-Gaa-0829	Gasterosteus aculeatus	95.9	6e-80	241
LLPS-Dio-0239	Dipodomys ordii	95.9	3e-80	241
LLPS-Orl-2635	Oryzias latipes	95.9	4e-80	241
LLPS-Leo-0516	Lepisosteus oculatus	95.9	1e-80	243
LLPS-Icp-1705	Ictalurus punctatus	95.9	2e-80	242
LLPS-Eqc-0756	Equus caballus	95.9	2e-80	242
LLPS-Gaga-0449	Gallus gallus	95.9	4e-80	241
LLPS-Anc-2621	Anolis carolinensis	95.9	4e-80	241
LLPS-Pof-0937	Poecilia formosa	95.9	3e-80	241
LLPS-Pat-2944	Pan troglodytes	95.9	4e-80	241
LLPS-Dar-0810	Danio rerio	95.9	1e-80	243
LLPS-Orn-1367	Oreochromis niloticus	95.9	3e-80	241
LLPS-Asm-0877	Astyanax mexicanus	95.87	2e-79	239
LLPS-Urm-1329	Ursus maritimus	95.08	3e-79	238
LLPS-Orc-0796	Oryctolagus cuniculus	95.08	2e-80	241
LLPS-Ict-0085	Ictidomys tridecemlineatus	94.74	1e-80	243
LLPS-Lac-1639	Latimeria chalumnae	94.64	9e-32	115
LLPS-Loa-3025	Loxodonta africana	94.31	2e-77	234
LLPS-Aon-0639	Aotus nancymaae	93.94	1e-91	271
LLPS-Ten-1642	Tetraodon nigroviridis	91.8	7e-75	228
LLPS-Man-0514	Macaca nemestrina	89.38	5e-78	236
LLPS-Tar-1987	Takifugu rubripes	89.34	2e-72	221
LLPS-Nol-1320	Nomascus leucogenys	88.27	9e-78	235
LLPS-Asfu-0581	Aspergillus fumigatus	86.96	2e-67	209
LLPS-Cis-0522	Ciona savignyi	84.62	6e-43	146
LLPS-Scm-1225	Scophthalmus maximus	84.38	3e-68	212
LLPS-Asc-0023	Aspergillus clavatus	84.3	1e-69	214
LLPS-Nef-0263	Neosartorya fischeri	84.3	1e-69	214
LLPS-Cii-0528	Ciona intestinalis	83.76	4e-67	209
LLPS-Nec-0187	Neurospora crassa	83.61	1e-67	209
LLPS-Pug-0475	Puccinia graminis	83.61	2e-68	211
LLPS-Asni-0949	Aspergillus niger	83.47	4e-69	213
LLPS-Asn-1016	Aspergillus nidulans	83.47	4e-69	213
LLPS-Ast-1099	Aspergillus terreus	83.47	4e-69	213
LLPS-Drm-0383	Drosophila melanogaster	83.33	3e-66	206
LLPS-Aso-0611	Aspergillus oryzae	82.64	3e-68	211
LLPS-Blg-0247	Blumeria graminis	82.64	8e-67	207
LLPS-Asf-0546	Aspergillus flavus	82.64	3e-68	211
LLPS-Tum-0439	Tuber melanosporum	82.64	9e-68	209
LLPS-Scs-0923	Sclerotinia sclerotiorum	82.64	3e-67	208
LLPS-Dos-0150	Dothistroma septosporum	82.64	1e-67	209
LLPS-Zyt-0854	Zymoseptoria tritici	82.5	1e-66	207
LLPS-Lem-0360	Leptosphaeria maculans	81.82	2e-67	209
LLPS-Pyt-0242	Pyrenophora teres	81.82	2e-67	209
LLPS-Pytr-0198	Pyrenophora triticirepentis	81.82	2e-67	209
LLPS-Mel-0063	Melampsora laricipopulina	81.72	6e-49	160
LLPS-Coo-0058	Colletotrichum orbiculare	81.15	3e-66	206
LLPS-Cogr-1153	Colletotrichum graminicola	81.15	4e-66	206
LLPS-Cog-0885	Colletotrichum gloeosporioides	81.15	4e-66	206
LLPS-Ved-0335	Verticillium dahliae	81.0	4e-51	167
LLPS-Put-0527	Puccinia triticina	80.95	2e-16	75.1
LLPS-Miv-0192	Microbotryum violaceum	80.33	1e-66	206
LLPS-Osl-0021	Ostreococcus lucimarinus	79.49	5e-63	197
LLPS-Fus-0181	Fusarium solani	79.13	1e-62	196
LLPS-Scj-0213	Schizosaccharomyces japonicus	78.51	8e-62	194
LLPS-Trv-1095	Trichoderma virens	78.26	2e-60	191
LLPS-Trr-0510	Trichoderma reesei	78.26	1e-60	191
LLPS-Cus-1320	Cucumis sativus	77.59	5e-59	187
LLPS-Sol-0975	Solanum lycopersicum	77.59	3e-59	187
LLPS-Hea-0641	Helianthus annuus	77.59	6e-59	187
LLPS-Thc-0352	Theobroma cacao	77.59	3e-59	187
LLPS-Prp-0969	Prunus persica	77.59	3e-59	187
LLPS-Viv-0098	Vitis vinifera	77.59	3e-59	187
LLPS-Gor-0709	Gossypium raimondii	77.59	3e-59	187
LLPS-Amt-1020	Amborella trichopoda	77.59	3e-59	188
LLPS-Usm-0526	Ustilago maydis	77.5	6e-59	187
LLPS-Scp-0438	Schizosaccharomyces pombe	77.05	1e-61	193
LLPS-Spr-0249	Sporisorium reilianum	77.05	5e-58	184
LLPS-Fuv-0508	Fusarium verticillioides	76.86	6e-64	200
LLPS-Fuo-0064	Fusarium oxysporum	76.86	7e-64	200
LLPS-Via-1209	Vigna angularis	76.72	1e-58	186
LLPS-Sot-0073	Solanum tuberosum	76.72	4e-59	187
LLPS-Vir-1228	Vigna radiata	76.72	1e-58	186
LLPS-Glm-0646	Glycine max	76.72	1e-58	186
LLPS-Php-1016	Physcomitrella patens	76.72	1e-58	186
LLPS-Mua-0416	Musa acuminata	76.72	3e-58	185
LLPS-Coc-1118	Corchorus capsularis	76.72	7e-59	187
LLPS-Pot-2067	Populus trichocarpa	76.72	7e-59	187
LLPS-Mae-0136	Manihot esculenta	76.72	1e-58	186
LLPS-Phv-1205	Phaseolus vulgaris	76.72	1e-58	186
LLPS-Chr-1275	Chlamydomonas reinhardtii	76.67	3e-54	175
LLPS-Abg-1942	Absidia glauca	76.03	3e-61	192
LLPS-Yal-0472	Yarrowia lipolytica	76.03	4e-61	192
LLPS-Scc-0786	Schizosaccharomyces cryophilus	76.03	4e-58	184
LLPS-Dac-0110	Daucus carota	76.03	8e-60	189
LLPS-Beb-0072	Beauveria bassiana	76.03	1e-62	197
LLPS-Nia-0354	Nicotiana attenuata	76.03	1e-59	189
LLPS-Arl-1340	Arabidopsis lyrata	75.86	4e-59	187
LLPS-Brn-0733	Brassica napus	75.86	5e-58	184
LLPS-Bro-1793	Brassica oleracea	75.86	4e-59	187
LLPS-Art-0680	Arabidopsis thaliana	75.86	4e-59	187
LLPS-Brr-1863	Brassica rapa	75.86	1e-58	186
LLPS-Gas-0156	Galdieria sulphuraria	75.65	1e-59	189
LLPS-Met-0441	Medicago truncatula	75.44	3e-56	180
LLPS-Phn-0062	Phaeosphaeria nodorum	75.21	1e-58	186
LLPS-Kop-0634	Komagataella pastoris	75.0	1e-59	189
LLPS-Sem-0214	Selaginella moellendorffii	75.0	6e-58	184
LLPS-Orp-0049	Oryza punctata	75.0	5e-58	184
LLPS-Orbr-1353	Oryza brachyantha	75.0	4e-58	184
LLPS-Sei-1067	Setaria italica	74.14	6e-57	184
LLPS-Zem-0102	Zea mays	74.14	3e-57	182
LLPS-Sob-1656	Sorghum bicolor	74.14	2e-57	182
LLPS-Orgl-0435	Oryza glumaepatula	73.17	3e-57	182
LLPS-Lep-0112	Leersia perrieri	73.17	2e-57	183
LLPS-Orb-1393	Oryza barthii	73.17	3e-57	182
LLPS-Ori-1106	Oryza indica	73.17	3e-57	182
LLPS-Orni-0751	Oryza nivara	73.17	3e-57	182
LLPS-Orm-1363	Oryza meridionalis	73.17	3e-57	182
LLPS-Orr-1025	Oryza rufipogon	73.17	3e-57	182
LLPS-Org-1309	Oryza glaberrima	73.17	3e-57	182
LLPS-Ors-0672	Oryza sativa	73.17	3e-57	182
LLPS-Hov-0674	Hordeum vulgare	72.36	3e-57	182
LLPS-Brd-0107	Brachypodium distachyon	72.36	3e-57	182
LLPS-Tra-1857	Triticum aestivum	72.36	3e-57	182
LLPS-Tru-1083	Triticum urartu	72.36	3e-57	182
LLPS-Cae-0095	Caenorhabditis elegans	72.03	5e-53	174
LLPS-Chc-0720	Chondrus crispus	71.79	1e-57	183
LLPS-Sac-0477	Saccharomyces cerevisiae	69.81	3e-48	160
LLPS-Cym-0056	Cyanidioschyzon merolae	68.33	9e-53	171
LLPS-Crn-0118	Cryptococcus neoformans	68.09	2e-38	134
LLPS-Asg-0280	Ashbya gossypii	67.92	2e-48	160
LLPS-Gag-0225	Gaeumannomyces graminis	44.53	1e-29	112
LLPS-Map-0020	Magnaporthe poae	44.53	1e-29	112
LLPS-Mao-0267	Magnaporthe oryzae	35.33	8e-21	89.7

LLPS-Mal-0799EIF1AX

Protein Sequence

Nucleotide Sequence

LLPS-Mal-0799
EIF1AX