• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Maf-4418
EGM_12044

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Kelch domain-containing protein 4
Gene Name: EGM_12044
Ensembl Gene: ENSMFAG00000000253.1
Ensembl Protein: ENSMFAP00000045145.1
Organism: Macaca fascicularis
Taxa ID: 9541
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGKKGKKEKK  GRGAEKTAAK  MEKKVSKRSR  KEEEDLEALI  AHFQTLDAKR  TQIVETPCPP  60
61    PSPRLNASLS  VHPEKDELIL  FGGEYFNGQK  TFLYNELYVY  NIRKDAWTKV  DIPSPPPRRC  120
121   AHQAVVVPQG  GGQLWVFGGE  FASPSGEQFY  HYKDLWVLHL  ATKTWEQVKS  TGGPSGRSGH  180
181   RMVAWKRQLI  LFGGFHESTR  DYIYYNDVYA  FNLDTFTWSK  LSPSGTGPTP  RSGCQMSVTP  240
241   QGGIVIYGGY  SKQRVKKDVD  KGTRHSDMFL  LKPEDGREDK  WVWTRMNPSG  VKPTPRSGFS  300
301   VAMAPNHQTL  FFGGVCDEEE  EESLAGEFFN  DLYFYDATRN  RWFEGQLKGP  KSEKKKRRRG  360
361   RREEPEGGSK  LACGGAGTQA  PVEVVKEVVT  EDGTVVTIKQ  VLSAPGSAGQ  PQSEDEDSLE  420
421   EAGSPTPGPC  PRSNAMLAVK  HGVLYVYGGM  FEAGDRQVTL  SDLHCLDLHR  MEAWKALVEM  480
481   DPETQEWLEE  TDSEEDSEEV  EGAEGGDEDE  DEDSGEESGA  ED  522
Nucleotide CDS Sequence (FASTA)
1     ATGGGCAAGA  AGGGCAAGAA  GGAGAAGAAG  GGCCGCGGCG  CGGAGAAGAC  GGCCGCCAAG  60
61    ATGGAGAAGA  AGGTGTCTAA  GCGCTCGCGG  AAGGAGGAGG  AAGACCTGGA  AGCGCTCATA  120
121   GCCCATTTCC  AGACGCTCGA  TGCCAAGAGG  ACTCAGATTG  TGGAAACTCC  GTGCCCCCCG  180
181   CCCTCACCAA  GGTTAAATGC  CTCCCTCTCG  GTTCATCCTG  AGAAAGATGA  ATTAATCCTT  240
241   TTCGGAGGTG  AATATTTCAA  CGGCCAAAAA  ACTTTTTTGT  ATAACGAGCT  CTATGTCTAC  300
301   AATATCAGAA  AGGACGCCTG  GACCAAAGTT  GACATCCCCA  GTCCACCTCC  GAGGCGCTGT  360
361   GCTCACCAGG  CGGTGGTGGT  GCCTCAAGGT  GGCGGACAGC  TGTGGGTCTT  TGGAGGGGAG  420
421   TTTGCCTCTC  CCAGCGGAGA  GCAGTTCTAC  CACTACAAGG  ATCTCTGGGT  CCTGCATTTG  480
481   GCCACCAAGA  CCTGGGAACA  AGTCAAATCA  ACAGGGGGTC  CTTCAGGTCG  GAGTGGACAT  540
541   CGGATGGTGG  CCTGGAAGAG  ACAGTTGATC  CTTTTTGGTG  GCTTCCATGA  GAGTACACGG  600
601   GATTACATCT  ACTACAATGA  TGTGTACGCC  TTTAATCTGG  ACACCTTCAC  GTGGAGCAAG  660
661   CTGTCCCCGT  CAGGCACGGG  GCCCACACCC  AGATCAGGCT  GCCAGATGTC  CGTCACTCCC  720
721   CAGGGCGGCA  TCGTCATCTA  CGGGGGCTAC  TCGAAACAGA  GAGTTAAGAA  AGACGTGGAC  780
781   AAGGGCACGC  GGCACTCGGA  CATGTTCCTG  CTGAAGCCGG  AGGACGGGAG  AGAAGACAAG  840
841   TGGGTGTGGA  CTCGGATGAA  CCCTTCGGGG  GTCAAGCCCA  CCCCACGGTC  TGGCTTTTCC  900
901   GTGGCCATGG  CCCCGAATCA  CCAGACGCTG  TTCTTCGGGG  GTGTCTGTGA  CGAGGAAGAG  960
961   GAGGAGAGCC  TGGCGGGCGA  GTTCTTCAAC  GATCTGTACT  TCTACGATGC  CACCAGGAAC  1020
1021  CGCTGGTTTG  AGGGACAGCT  GAAGGGGCCC  AAGTCTGAGA  AGAAGAAGCG  CAGGCGGGGC  1080
1081  AGAAGAGAGG  AGCCCGAAGG  TGGCAGCAAG  CTGGCGTGTG  GGGGAGCTGG  CACGCAGGCG  1140
1141  CCTGTGGAGG  TGGTCAAGGA  GGTGGTGACC  GAGGATGGGA  CCGTGGTCAC  CATTAAGCAG  1200
1201  GTGCTCTCCG  CCCCAGGCTC  GGCAGGGCAG  CCCCAGTCTG  AGGACGAAGA  CAGCCTCGAG  1260
1261  GAGGCCGGCA  GCCCCACACC  TGGGCCGTGT  CCTCGCTCCA  ACGCCATGCT  GGCCGTGAAG  1320
1321  CACGGGGTGC  TCTACGTCTA  CGGGGGCATG  TTTGAGGCTG  GCGACCGCCA  GGTCACCCTC  1380
1381  AGCGACCTGC  ACTGCCTGGA  CCTGCACAGG  ATGGAGGCGT  GGAAGGCCTT  GGTGGAGATG  1440
1441  GACCCAGAAA  CTCAGGAGTG  GCTGGAGGAG  ACAGACTCGG  AAGAGGACAG  TGAGGAGGTT  1500
1501  GAAGGTGCTG  AGGGTGGAGA  CGAGGATGAG  GACGAAGACA  GCGGAGAGGA  GAGCGGTGCG  1560
1561  GAGGACTGA  1569

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mam-3462Macaca mulatta99.780.0 859
LLPS-Mal-4704Mandrillus leucophaeus99.780.0 859
LLPS-Paa-1168Papio anubis98.680.0 850
LLPS-Cea-3834Cercocebus atys98.020.0 877
LLPS-Chs-4156Chlorocebus sabaeus98.020.0 848
LLPS-Rhb-2728Rhinopithecus bieti97.360.0 839
LLPS-Gog-4292Gorilla gorilla96.480.0 856
LLPS-Pat-1037Pan troglodytes96.260.0 855
LLPS-Pap-0126Pan paniscus96.260.0 860
LLPS-Hos-4120Homo sapiens96.260.0 858
LLPS-Nol-2928Nomascus leucogenys96.040.0 850
LLPS-Poa-3868Pongo abelii94.70.0 580
LLPS-Aon-1023Aotus nancymaae93.00.0 701
LLPS-Caj-3114Callithrix jacchus91.650.0 798
LLPS-Man-3127Macaca nemestrina89.910.0 733
LLPS-Ova-4292Ovis aries88.50.0 591
LLPS-Cas-3506Carlito syrichta85.680.0 769
LLPS-Urm-3713Ursus maritimus85.240.0 769
LLPS-Myl-2896Myotis lucifugus84.80.0 772
LLPS-Aim-3078Ailuropoda melanoleuca84.360.0 764
LLPS-Ict-0408Ictidomys tridecemlineatus84.140.0 757
LLPS-Fec-2759Felis catus83.810.0 747
LLPS-Bot-2811Bos taurus83.260.0 755
LLPS-Dio-3778Dipodomys ordii83.040.0 711
LLPS-Orc-0525Oryctolagus cuniculus82.890.0 758
LLPS-Sus-4065Sus scrofa82.640.0 737
LLPS-Caf-0728Canis familiaris82.460.0 754
LLPS-Otg-4605Otolemur garnettii82.160.0 756
LLPS-Mup-1094Mustela putorius furo81.950.0 616
LLPS-Cap-1154Cavia porcellus81.280.0 743
LLPS-Mum-4208Mus musculus81.280.0 739
LLPS-Mea-2651Mesocricetus auratus81.060.0 736
LLPS-Fud-1371Fukomys damarensis80.620.0 735
LLPS-Ran-4089Rattus norvegicus79.490.0 609
LLPS-Ora-2205Ornithorhynchus anatinus79.070.0 733
LLPS-Sah-1937Sarcophilus harrisii77.750.0 708
LLPS-Ten-2663Tetraodon nigroviridis77.715e-95 294
LLPS-Mod-4282Monodelphis domestica76.540.0 684
LLPS-Anp-0936Anas platyrhynchos76.370.0 689
LLPS-Meg-3246Meleagris gallopavo76.320.0 686
LLPS-Eqc-0930Equus caballus75.330.0 696
LLPS-Pes-1225Pelodiscus sinensis73.80.0 669
LLPS-Lac-3843Latimeria chalumnae72.210.0 638
LLPS-Leo-3928Lepisosteus oculatus71.370.0 616
LLPS-Dar-4273Danio rerio70.150.0 617
LLPS-Icp-3791Ictalurus punctatus68.850.0 632
LLPS-Scf-3355Scleropages formosus68.040.0 600
LLPS-Orn-1526Oreochromis niloticus67.970.0 617
LLPS-Xim-0167Xiphophorus maculatus67.970.0 620
LLPS-Orl-0151Oryzias latipes67.180.0 620
LLPS-Pof-1653Poecilia formosa67.110.0 629
LLPS-Xet-2837Xenopus tropicalis66.740.0 593
LLPS-Scm-2146Scophthalmus maximus66.520.0 602
LLPS-Asm-3222Astyanax mexicanus65.160.0 602
LLPS-Anc-4018Anolis carolinensis64.093e-111 343
LLPS-Tar-2856Takifugu rubripes63.440.0 593
LLPS-Gaa-3557Gasterosteus aculeatus63.340.0 582
LLPS-Usm-1361Ustilago maydis52.949e-0962.4
LLPS-Spr-0100Sporisorium reilianum47.469e-0962.4
LLPS-Cii-2084Ciona intestinalis46.76e-141 421
LLPS-Nec-1260Neurospora crassa46.671e-0862.0
LLPS-Sol-0086Solanum lycopersicum44.962e-62 213
LLPS-Mae-1943Manihot esculenta43.752e-75 256
LLPS-Sot-1679Solanum tuberosum42.53e-71 246
LLPS-Sem-2057Selaginella moellendorffii42.195e-76 257
LLPS-Amt-0514Amborella trichopoda40.097e-85 291
LLPS-Tra-1829Triticum aestivum39.833e-93 303
LLPS-Hea-1961Helianthus annuus39.353e-89 294
LLPS-Asni-0125Aspergillus niger39.113e-41 154
LLPS-Hov-0571Hordeum vulgare38.842e-88 292
LLPS-Tru-1095Triticum urartu38.772e-61 218
LLPS-Drm-1548Drosophila melanogaster38.751e-102 325
LLPS-Brd-2278Brachypodium distachyon38.561e-88 293
LLPS-Sob-1903Sorghum bicolor38.496e-91 298
LLPS-Glm-2823Glycine max38.484e-89 293
LLPS-Phv-0763Phaseolus vulgaris38.442e-90 297
LLPS-Org-0209Oryza glaberrima38.46e-89 293
LLPS-Orb-0989Oryza barthii38.46e-89 293
LLPS-Orni-1428Oryza nivara38.49e-89 293
LLPS-Orgl-0459Oryza glumaepatula38.47e-89 293
LLPS-Ors-0608Oryza sativa38.198e-89 293
LLPS-Orr-0937Oryza rufipogon38.191e-88 293
LLPS-Ori-0473Oryza indica38.191e-88 292
LLPS-Orbr-0750Oryza brachyantha38.093e-88 292
LLPS-Orm-1262Oryza meridionalis38.04e-90 295
LLPS-Put-1226Puccinia triticina37.986e-49 183
LLPS-Met-0513Medicago truncatula37.911e-88 293
LLPS-Lep-1173Leersia perrieri37.872e-87 290
LLPS-Prp-1739Prunus persica37.663e-85 283
LLPS-Pot-1668Populus trichocarpa37.56e-86 286
LLPS-Art-2977Arabidopsis thaliana37.151e-81 274
LLPS-Bro-0535Brassica oleracea36.972e-83 279
LLPS-Brn-1015Brassica napus36.972e-83 279
LLPS-Arl-1789Arabidopsis lyrata36.734e-80 270
LLPS-Brr-0007Brassica rapa36.74e-81 278
LLPS-Viv-1118Vitis vinifera36.658e-83 277
LLPS-Thc-0372Theobroma cacao36.62e-83 279
LLPS-Coc-1437Corchorus capsularis36.582e-82 281
LLPS-Mel-0687Melampsora laricipopulina36.553e-72 249
LLPS-Zem-2396Zea mays36.363e-79 269
LLPS-Cus-1133Cucumis sativus36.344e-84 281
LLPS-Nia-2567Nicotiana attenuata36.292e-84 282
LLPS-Php-2233Physcomitrella patens36.291e-83 282
LLPS-Gor-1628Gossypium raimondii36.217e-84 280
LLPS-Tum-0975Tuber melanosporum36.043e-41 161
LLPS-Vir-0709Vigna radiata35.641e-70 242
LLPS-Sac-0097Saccharomyces cerevisiae35.097e-43 166
LLPS-Orp-2300Oryza punctata35.021e-70 243
LLPS-Dos-1109Dothistroma septosporum34.183e-67 235
LLPS-Chr-0622Chlamydomonas reinhardtii33.954e-1271.6
LLPS-Miv-0614Microbotryum violaceum33.712e-63 225
LLPS-Chc-0903Chondrus crispus32.95e-65 233
LLPS-Mua-1546Musa acuminata32.699e-32 131
LLPS-Kop-0970Komagataella pastoris32.572e-52 194
LLPS-Pug-0110Puccinia graminis32.223e-63 225
LLPS-Via-1335Vigna angularis32.034e-53 194
LLPS-Fus-1298Fusarium solani32.013e-55 202
LLPS-Pyt-1571Pyrenophora teres31.977e-57 207
LLPS-Osl-0683Ostreococcus lucimarinus31.893e-68 235
LLPS-Dac-1082Daucus carota31.741e-22 104
LLPS-Fuv-1584Fusarium verticillioides31.731e-55 203
LLPS-Cog-1257Colletotrichum gloeosporioides31.714e-56 205
LLPS-Coo-0695Colletotrichum orbiculare31.715e-59 213
LLPS-Pytr-1470Pyrenophora triticirepentis31.625e-58 210
LLPS-Yal-1186Yarrowia lipolytica31.532e-57 207
LLPS-Lem-0071Leptosphaeria maculans31.517e-55 201
LLPS-Phn-0865Phaeosphaeria nodorum31.283e-56 205
LLPS-Nef-1419Neosartorya fischeri31.241e-59 214
LLPS-Asfu-1034Aspergillus fumigatus31.242e-59 214
LLPS-Asn-1431Aspergillus nidulans31.191e-56 206
LLPS-Fuo-1557Fusarium oxysporum30.952e-55 202
LLPS-Zyt-0249Zymoseptoria tritici30.953e-60 216
LLPS-Aso-0043Aspergillus oryzae30.718e-56 204
LLPS-Ved-0728Verticillium dahliae30.674e-57 207
LLPS-Asc-0811Aspergillus clavatus30.392e-57 208
LLPS-Asg-1149Ashbya gossypii30.386e-55 201
LLPS-Beb-1333Beauveria bassiana29.852e-55 203
LLPS-Ast-0652Aspergillus terreus29.677e-55 201
LLPS-Gag-0477Gaeumannomyces graminis29.631e-48 184
LLPS-Abg-0778Absidia glauca29.393e-1686.3
LLPS-Trr-0361Trichoderma reesei29.251e-54 201
LLPS-Trv-1409Trichoderma virens29.221e-55 203
LLPS-Scs-0383Sclerotinia sclerotiorum27.213e-1273.9
LLPS-Sei-1711Setaria italica26.928e-1579.3
LLPS-Blg-1117Blumeria graminis26.899e-2199.4
LLPS-Asf-1517Aspergillus flavus26.167e-2096.7