LLPS-Loa-a237
TIMM50
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mitochondrial import inner membrane translocase subunit TIM50 |
| Gene Name: | TIMM50 |
| Ensembl Gene: | ENSLAFG00000023081.2 |
| Ensembl Protein: | ENSLAFP00000017924.2 |
| Organism: | Loxodonta africana |
| Taxa ID: | 9785 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLAFT00000022563.2 | ENSLAFP00000017924.2 |
| Ensembl | ENSLAFT00000026953.1 | ENSLAFP00000022893.1 |
| UniProt | G3U4Y5, G3U4Y5_LOXAF | |
| Entrez | 100661861 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAASAALCLR LRTGLRLGAR GLCTRLATPS PRAPDQAAEI RSRGGTQAQG SQKQQQQQRG 60 61 SEGPSYAKKV ALWIAGLLGA GGTVSVVYIF GNNSVDETGA KIPDEFDNDP VLVQQLRRTY 120 121 KYFKDYRQMI IEPTSPCLLP DPLREPYYQP PYTLVLELTG VLLHPEWSLA TGWRFKKRPG 180 181 IETLFQQLAP LYEIVIFTSE TGMTAFPLID SVDPHGFISY RLFRDATRYM EGHHVKVPGH 240 241 SCLNRDPARV VIVDCKKEAF RLQPYNGVAL RPWDGNSDDR VLLDLSAFLK TIALNNVEDV 300 301 RTVLEHYALE EDPLEAFKQR QSRLEQQGGT AALAELSKSS KQNLFFSSLT SRLWPRSKQP 360 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCCT CGGCGGCGCT GTGCTTGCGC TTGCGGACCG GGCTCCGGCT CGGCGCCCGG 60 61 GGGCTGTGCA CGAGGCTGGC GACACCGTCC CCCCGGGCCC CGGACCAGGC TGCAGAGATC 120 121 CGGAGCCGTG GGGGCACTCA GGCCCAGGGG TCACAGAAGC AGCAGCAGCA GCAGCGGGGG 180 181 TCTGAGGGCC CTAGCTATGC CAAGAAAGTC GCACTCTGGA TCGCAGGGCT GCTCGGGGCT 240 241 GGTGGGACCG TGAGCGTTGT CTATATCTTT GGAAACAACT CTGTGGATGA AACTGGTGCC 300 301 AAGATTCCTG ATGAATTCGA CAATGATCCA GTCCTGGTCC AGCAGTTGCG CCGGACGTAC 360 361 AAATATTTCA AAGATTATAG ACAGATGATC ATCGAGCCCA CCAGCCCCTG CCTGCTCCCA 420 421 GACCCCCTGC GGGAGCCGTA CTACCAGCCG CCCTACACAC TGGTCTTGGA GCTCACTGGC 480 481 GTCCTCTTGC ACCCTGAGTG GTCGCTGGCC ACTGGCTGGA GGTTTAAGAA GCGTCCAGGC 540 541 ATCGAGACCT TGTTCCAGCA GCTCGCCCCT TTGTATGAAA TTGTCATTTT TACGTCAGAG 600 601 ACTGGCATGA CTGCGTTTCC TCTCATAGAC AGCGTGGACC CCCATGGCTT CATCTCCTAT 660 661 CGCCTCTTCC GGGATGCCAC ACGATACATG GAGGGGCACC ATGTTAAGGT GCCGGGACAT 720 721 TCGTGTCTGA ATCGGGACCC AGCCCGTGTG GTTATTGTGG ACTGCAAGAA GGAAGCCTTT 780 781 CGCTTACAGC CCTACAACGG CGTTGCCCTG CGGCCTTGGG ATGGCAACTC TGATGACCGG 840 841 GTCTTGTTGG ACCTGTCCGC CTTCCTCAAG ACCATTGCGC TCAACAATGT GGAGGATGTC 900 901 CGGACAGTGC TGGAGCACTA CGCACTGGAG GAGGACCCGC TTGAGGCTTT CAAACAGCGG 960 961 CAGAGCCGGT TAGAGCAGCA GGGAGGAACA GCAGCCCTGG CTGAGCTCTC CAAGTCCAGC 1020 1021 AAGCAGAACC TCTTCTTCAG CTCCCTCACC AGCCGCTTGT GGCCTCGCTC CAAACAGCCC 1080 1081 TAA 1083 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | Nuclear speck | |
Cellular Component | TIM23 mitochondrial import inner membrane translocase complex | |
Molecular Function | Interleukin-2 receptor binding | |
Molecular Function | Protein serine/threonine phosphatase activity | |
Molecular Function | Protein tyrosine phosphatase activity | |
Molecular Function | Ribonucleoprotein complex binding | |
Biological Process | Mitochondrial membrane organization | |
Biological Process | Protein transport | |
Biological Process | Release of cytochrome c from mitochondria |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a244 | Homo sapiens | 0.0 | 629 | undefined |
| LLPS-Mum-a242 | Mus musculus | 0.0 | 620 | undefined |