LLPS-Loa-4324
PAK4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | p21 (RAC1) activated kinase 4 |
| Gene Name: | PAK4 |
| Ensembl Gene: | ENSLAFG00000005252.3 |
| Ensembl Protein: | ENSLAFP00000004398.3 |
| Organism: | Loxodonta africana |
| Taxa ID: | 9785 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLAFT00000005252.3 | ENSLAFP00000004398.3 |
| UniProt | G3SVV4, G3SVV4_LOXAF |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MFGKKKKRVE ISAPSNFEHR RVHTGFDQHE QKFTGLPRQW QSLIEESARR PKPLIDPACI 60 61 TSIQPGAPKT IVRGSKGAKD GALTLLLDEF ENMSVTRSNS LRRDSPPPPA RARQENGLPQ 120 121 EQAAMARGGP DKAGSRGQAT TRSEAGGGSS DRRRVGPEKR PKPSREGPRV PQESSWDKRP 180 181 LSGPDVSGAK LAAGRPFNTY PRDTDHPSRG AQGEPHGRAP NGPSTGGLSA PQSSSRLPTQ 240 241 VRSAPSPGVL GPHASEPQLA PLARTPAAPA APGPPGPRSP QREPQRVSHE QFRAALQLVV 300 301 DPGDPRSYLD NFIKIGEGST GIVCIATVRS SGKLVAVKKM DLRKQQRREL LFNEVVIMRD 360 361 YQHENVVEMY NSYLVGDELW VVMEFLEGGA LTDIVTHTRM NEEQIAAVCL AVLQALSVLH 420 421 AQGVIHRDIK SDSILLTHDG RVKLSDFGFC AQVSKEVPRR KSLVGTPYWM APELISRLPY 480 481 GPEVDIWSLG VMVIEMVDGE PPYFNEPPLK AMKMIRDNLP PRLKNLHKVS PSLKGFLDRL 540 541 LVRDPAQRAT AAELLKHPFL AKAGPPASIV PLMRQNRTR 579 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTTTGGTA AGAAGAAGAA GCGGGTGGAG ATCTCGGCGC CCTCTAACTT TGAGCACCGC 60 61 CGCGTGCACA CGGGCTTTGA CCAGCACGAG CAGAAGTTCA CAGGGCTGCC CCGCCAGTGG 120 121 CAGAGCCTGA TCGAGGAGTC GGCGCGCCGG CCCAAGCCGC TCATTGACCC TGCCTGCATC 180 181 ACCTCCATCC AGCCTGGGGC CCCCAAGACC ATCGTGCGGG GCAGCAAAGG TGCCAAGGAT 240 241 GGGGCCCTCA CGCTGCTGCT CGACGAGTTT GAGAACATGT CGGTGACACG CTCCAACTCC 300 301 CTGCGGAGAG ACAGCCCGCC ACCCCCTGCC CGCGCCCGCC AGGAGAACGG GCTGCCCCAG 360 361 GAGCAGGCTG CCATGGCCAG AGGGGGCCCG GACAAAGCAG GCAGCCGAGG CCAGGCCACC 420 421 ACTCGCAGCG AGGCGGGTGG TGGCAGCAGT GACAGGCGGC GGGTGGGGCC GGAGAAGAGG 480 481 CCCAAGCCTT CCAGGGAGGG CCCAAGGGTG CCCCAGGAGT CCTCCTGGGA CAAACGCCCC 540 541 CTCTCTGGGC CTGATGTCAG CGGGGCGAAA CTGGCAGCTG GCCGGCCCTT TAACACATAC 600 601 CCGCGGGACA CAGACCACCC ATCCCGTGGT GCCCAGGGGG AGCCTCACGG CAGGGCCCCC 660 661 AACGGGCCAT CCACAGGGGG TCTGTCTGCC CCCCAGTCCT CCTCCCGGCT CCCCACCCAA 720 721 GTCCGCAGCG CCCCCAGCCC GGGAGTGCTG GGCCCCCATG CCTCTGAGCC CCAGCTGGCC 780 781 CCTCTGGCCC GCACCCCTGC TGCCCCTGCC GCCCCCGGGC CCCCTGGCCC CCGCTCACCC 840 841 CAGCGGGAAC CCCAGCGGGT ATCCCATGAG CAGTTCCGGG CCGCCCTGCA GCTGGTGGTA 900 901 GACCCAGGTG ACCCTCGCTC CTACCTGGAC AACTTCATCA AGATCGGCGA GGGCTCCACG 960 961 GGCATCGTCT GCATTGCCAC CGTGCGCAGC TCCGGCAAGC TGGTGGCCGT CAAGAAGATG 1020 1021 GACCTGCGCA AGCAGCAGAG GCGTGAACTG CTGTTCAACG AGGTGGTGAT CATGCGGGAC 1080 1081 TACCAGCACG AGAACGTGGT GGAGATGTAC AACAGCTACC TGGTGGGAGA TGAGCTCTGG 1140 1141 GTGGTGATGG AGTTCCTGGA GGGAGGTGCC CTCACCGACA TTGTCACCCA CACCAGGATG 1200 1201 AACGAGGAAC AGATTGCCGC CGTGTGCCTG GCTGTGCTGC AGGCCCTGTC TGTGCTCCAC 1260 1261 GCCCAGGGTG TTATCCACCG GGACATCAAG AGTGACTCCA TCCTGCTGAC CCACGACGGC 1320 1321 CGGGTGAAGC TGTCAGACTT TGGGTTCTGC GCCCAGGTGA GCAAGGAGGT GCCACGGAGG 1380 1381 AAGTCGCTGG TGGGCACACC CTACTGGATG GCCCCGGAGC TCATCTCCCG CCTTCCCTAT 1440 1441 GGGCCAGAGG TGGACATCTG GTCTCTGGGA GTGATGGTGA TCGAGATGGT GGACGGGGAG 1500 1501 CCCCCCTATT TCAACGAGCC GCCCCTCAAA GCCATGAAGA TGATTCGGGA CAACCTGCCA 1560 1561 CCCCGGCTGA AGAACCTGCA CAAGGTGTCG CCATCCCTGA AGGGCTTTCT GGACCGCCTG 1620 1621 CTGGTGCGTG ACCCTGCCCA GCGGGCCACA GCAGCTGAGC TGCTGAAGCA TCCGTTCCTG 1680 1681 GCCAAGGCGG GACCGCCCGC CAGCATCGTG CCCCTCATGC GCCAAAACCG CACCAGATGA 1740 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Anc-3054 | Anolis carolinensis | 95.56 | 0.0 | 588 |
| LLPS-Scm-2381 | Scophthalmus maximus | 92.15 | 0.0 | 572 |
| LLPS-Ten-0858 | Tetraodon nigroviridis | 92.15 | 0.0 | 573 |
| LLPS-Hos-2593 | Homo sapiens | 92.06 | 0.0 | 984 |
| LLPS-Otg-2832 | Otolemur garnettii | 91.85 | 0.0 | 987 |
| LLPS-Leo-1869 | Lepisosteus oculatus | 91.81 | 0.0 | 569 |
| LLPS-Gaa-3730 | Gasterosteus aculeatus | 91.81 | 0.0 | 571 |
| LLPS-Dio-3290 | Dipodomys ordii | 91.51 | 0.0 | 961 |
| LLPS-Cap-3230 | Cavia porcellus | 91.06 | 0.0 | 988 |
| LLPS-Caf-2701 | Canis familiaris | 90.89 | 0.0 | 983 |
| LLPS-Fec-3190 | Felis catus | 90.73 | 0.0 | 979 |
| LLPS-Pat-3702 | Pan troglodytes | 90.57 | 0.0 | 979 |
| LLPS-Nol-4361 | Nomascus leucogenys | 90.44 | 0.0 | 980 |
| LLPS-Caj-3807 | Callithrix jacchus | 90.4 | 0.0 | 972 |
| LLPS-Cea-0263 | Cercocebus atys | 90.13 | 0.0 | 981 |
| LLPS-Rhb-1607 | Rhinopithecus bieti | 90.08 | 0.0 | 976 |
| LLPS-Paa-3159 | Papio anubis | 89.97 | 0.0 | 979 |
| LLPS-Sus-4817 | Sus scrofa | 89.71 | 0.0 | 974 |
| LLPS-Man-4800 | Macaca nemestrina | 89.63 | 0.0 | 972 |
| LLPS-Maf-4056 | Macaca fascicularis | 89.52 | 0.0 | 976 |
| LLPS-Mam-4312 | Macaca mulatta | 89.52 | 0.0 | 976 |
| LLPS-Orc-2934 | Oryctolagus cuniculus | 89.41 | 0.0 | 984 |
| LLPS-Bot-4495 | Bos taurus | 89.39 | 0.0 | 982 |
| LLPS-Chs-0317 | Chlorocebus sabaeus | 89.13 | 0.0 | 971 |
| LLPS-Mum-3467 | Mus musculus | 89.06 | 0.0 | 970 |
| LLPS-Aon-3126 | Aotus nancymaae | 89.06 | 0.0 | 961 |
| LLPS-Mup-2645 | Mustela putorius furo | 88.93 | 0.0 | 944 |
| LLPS-Ran-2874 | Rattus norvegicus | 88.89 | 0.0 | 966 |
| LLPS-Poa-3662 | Pongo abelii | 88.53 | 0.0 | 843 |
| LLPS-Myl-2595 | Myotis lucifugus | 88.22 | 0.0 | 951 |
| LLPS-Fud-1088 | Fukomys damarensis | 87.92 | 0.0 | 952 |
| LLPS-Mea-0788 | Mesocricetus auratus | 87.37 | 0.0 | 955 |
| LLPS-Eqc-4578 | Equus caballus | 86.67 | 0.0 | 553 |
| LLPS-Aim-1628 | Ailuropoda melanoleuca | 85.91 | 0.0 | 941 |
| LLPS-Ere-0804 | Erinaceus europaeus | 83.16 | 1e-170 | 509 |
| LLPS-Mod-3861 | Monodelphis domestica | 75.85 | 0.0 | 844 |
| LLPS-Gog-4207 | Gorilla gorilla | 75.26 | 3e-154 | 466 |
| LLPS-Mal-0510 | Mandrillus leucophaeus | 75.26 | 3e-154 | 466 |
| LLPS-Pap-4440 | Pan paniscus | 75.26 | 1e-152 | 461 |
| LLPS-Ict-3095 | Ictidomys tridecemlineatus | 75.26 | 6e-155 | 468 |
| LLPS-Pes-1531 | Pelodiscus sinensis | 74.74 | 1e-156 | 472 |
| LLPS-Fia-3116 | Ficedula albicollis | 74.74 | 2e-157 | 473 |
| LLPS-Cas-3733 | Carlito syrichta | 74.57 | 9e-154 | 464 |
| LLPS-Meg-2919 | Meleagris gallopavo | 74.4 | 1e-160 | 471 |
| LLPS-Anp-2872 | Anas platyrhynchos | 74.4 | 2e-156 | 473 |
| LLPS-Tag-1086 | Taeniopygia guttata | 74.4 | 3e-157 | 473 |
| LLPS-Tut-1520 | Tursiops truncatus | 74.23 | 1e-152 | 461 |
| LLPS-Cii-1148 | Ciona intestinalis | 73.78 | 1e-152 | 462 |
| LLPS-Sah-2141 | Sarcophilus harrisii | 73.04 | 4e-151 | 457 |
| LLPS-Dar-2326 | Danio rerio | 72.01 | 2e-153 | 464 |
| LLPS-Orl-3863 | Oryzias latipes | 71.33 | 3e-152 | 461 |
| LLPS-Orn-4130 | Oreochromis niloticus | 71.33 | 3e-150 | 454 |
| LLPS-Asm-3218 | Astyanax mexicanus | 70.99 | 1e-150 | 456 |
| LLPS-Tar-3860 | Takifugu rubripes | 70.99 | 2e-150 | 454 |
| LLPS-Xim-1162 | Xiphophorus maculatus | 70.99 | 3e-151 | 458 |
| LLPS-Pof-1695 | Poecilia formosa | 70.99 | 2e-151 | 459 |
| LLPS-Ova-0142 | Ovis aries | 70.76 | 3e-130 | 403 |
| LLPS-Cis-1673 | Ciona savignyi | 70.63 | 3e-143 | 437 |
| LLPS-Icp-0980 | Ictalurus punctatus | 70.31 | 6e-151 | 457 |
| LLPS-Gaga-2005 | Gallus gallus | 69.1 | 0.0 | 776 |
| LLPS-Xet-1676 | Xenopus tropicalis | 63.21 | 0.0 | 722 |
| LLPS-Scf-4088 | Scleropages formosus | 61.72 | 0.0 | 704 |
| LLPS-Cae-1502 | Caenorhabditis elegans | 60.9 | 3e-115 | 359 |
| LLPS-Drm-2255 | Drosophila melanogaster | 54.7 | 1e-100 | 330 |
| LLPS-Ora-0754 | Ornithorhynchus anatinus | 54.55 | 5e-102 | 326 |
| LLPS-Lac-1238 | Latimeria chalumnae | 53.66 | 3e-105 | 334 |
| LLPS-Urm-2117 | Ursus maritimus | 52.96 | 3e-103 | 329 |
| LLPS-Abg-0755 | Absidia glauca | 50.88 | 3e-96 | 316 |
| LLPS-Asn-0596 | Aspergillus nidulans | 50.18 | 2e-95 | 317 |
| LLPS-Nef-0386 | Neosartorya fischeri | 49.82 | 6e-95 | 315 |
| LLPS-Asfu-0363 | Aspergillus fumigatus | 49.82 | 3e-95 | 315 |
| LLPS-Kop-1456 | Komagataella pastoris | 49.65 | 2e-95 | 317 |
| LLPS-Fus-1143 | Fusarium solani | 49.65 | 5e-93 | 310 |
| LLPS-Fuo-0431 | Fusarium oxysporum | 49.65 | 1e-92 | 309 |
| LLPS-Asc-1516 | Aspergillus clavatus | 49.47 | 5e-94 | 312 |
| LLPS-Asg-1412 | Ashbya gossypii | 49.32 | 3e-94 | 316 |
| LLPS-Asni-1574 | Aspergillus niger | 48.95 | 4e-94 | 313 |
| LLPS-Aso-1366 | Aspergillus oryzae | 48.95 | 2e-94 | 314 |
| LLPS-Asf-1216 | Aspergillus flavus | 48.95 | 2e-94 | 314 |
| LLPS-Trr-0785 | Trichoderma reesei | 48.59 | 8e-93 | 309 |
| LLPS-Pytr-0173 | Pyrenophora triticirepentis | 48.59 | 9e-93 | 310 |
| LLPS-Scs-0838 | Sclerotinia sclerotiorum | 48.42 | 1e-92 | 307 |
| LLPS-Spr-1259 | Sporisorium reilianum | 48.1 | 9e-93 | 305 |
| LLPS-Dos-1365 | Dothistroma septosporum | 47.77 | 1e-95 | 313 |
| LLPS-Zyt-0111 | Zymoseptoria tritici | 47.42 | 3e-95 | 311 |