LLPS-Loa-1954
PLEKHG6
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pleckstrin homology and RhoGEF domain containing G6 |
| Gene Name: | PLEKHG6 |
| Ensembl Gene: | ENSLAFG00000021440.2 |
| Ensembl Protein: | ENSLAFP00000016484.2 |
| Organism: | Loxodonta africana |
| Taxa ID: | 9785 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLAFT00000022345.2 | ENSLAFP00000016484.2 |
| UniProt | G3TMV2, G3TMV2_LOXAF |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQTFGPPDEG PLQGLVASLI ETYGGRHRAS TQSTAGSLYP RGGAVPDPSR RLLQNYVPFV 60 61 KSSGQTRGLA PIWLREPEPE KRHGGHLGAG TPHSPKLKEV TKAHELKVRL HTFSMFGMPR 120 121 LPPEDRRHWE IGESSDSGLA IEKTWRELVP GHKEMSRELC HQQEALWELL TTEVIYVTKL 180 181 KIMTDLLAAG LLNLQRVGLL TEVSVETLFG NVPSLIRAHR GFWEEVLGPT LEETRASGQP 240 241 LDPVSLQNGF LTFGQRFHPY VQYCLRVKQT MAYAREQQEN NPLFQIFVQW CEKHKRSGRQ 300 301 MLGDLLIKPH QRITKYPLLL QAVLKRSPEA RAQEALNTMI ASVESFLRYI NRQVRQGEEQ 360 361 ESLVAVAQRI GPYEVLEPSS EEVEKNLRPF STLDLTSPML GVSPEHTRQL LLEGAVRVKE 420 421 GREAKLDVYL FLFTDVLLVT KPQRKADKAK VIRPPLMLEK LVFRPLRDPS SFLVINLTEF 480 481 QCVSSALIVY CPSSTDRAQW LEKTQKAQAT LQKLKIEEYV QQKRDLLALY RDRDRDQESP 540 541 GTRPSTPSPE GSQGSAEGRA PEFSTIIPHL VVTEDTDEDA PSAPDDTSDS GYSTLIPGSP 600 601 KGPRSPLSRQ RQRALRRDPR LTFSTLDLRN VPLRPQPPNS QAPQRRSAPD LPEEGIQRGS 660 661 SLPKGDPPTW SEEEDGTSGG GNAGVGTLHR ARLRGQLSPS PIHVDSAGES PWDSSGDEDE 720 721 ESLFLEPSHV PSPRPLQAED MLRQIREELA SQRVEDAPEP PSARPRKLTR LQLQRMRGPH 780 781 IIQLDTPLST SEV 793 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCAGACCT TTGGTCCTCC AGATGAGGGC CCCCTCCAAG GCCTTGTGGC CTCCCTCATA 60 61 GAGACTTATG GGGGCCGGCA TCGGGCCTCC ACCCAGAGCA CTGCTGGCAG TCTCTATCCC 120 121 CGAGGAGGTG CTGTGCCGGA TCCCAGTCGC CGCCTCCTCC AGAACTATGT CCCTTTCGTC 180 181 AAGAGCTCTG GCCAGACCCG GGGCCTGGCT CCCATATGGC TGCGAGAACC AGAGCCTGAG 240 241 AAGCGGCATG GTGGCCATTT GGGGGCTGGC ACACCCCACT CCCCCAAACT CAAGGAGGTC 300 301 ACCAAGGCCC ATGAGCTGAA AGTGCGGCTG CACACGTTCA GCATGTTTGG GATGCCCCGC 360 361 CTGCCCCCTG AGGATCGTCG GCACTGGGAG ATAGGGGAGA GCAGTGACAG TGGCCTGGCC 420 421 ATCGAAAAGA CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCG GGAGCTTTGC 480 481 CACCAACAGG AAGCGCTGTG GGAGCTACTG ACCACAGAGG TGATCTACGT GACAAAGCTC 540 541 AAGATCATGA CTGATCTCCT AGCTGCTGGA TTGCTGAACC TGCAGCGAGT GGGACTGCTG 600 601 ACTGAAGTAT CTGTTGAGAC CCTGTTTGGA AACGTCCCCA GCCTGATTCG AGCCCACCGG 660 661 GGCTTTTGGG AGGAGGTGCT GGGACCCACC CTGGAGGAGA CTCGAGCCTC AGGCCAGCCT 720 721 CTGGACCCTG TCAGCCTGCA AAATGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAC 780 781 GTCCAGTACT GCCTGCGAGT GAAACAGACC ATGGCTTACG CCCGGGAACA GCAAGAAAAC 840 841 AACCCTCTCT TCCAGATCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC GGGGAGGCAG 900 901 ATGCTGGGTG ACTTGCTCAT TAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 960 961 CAGGCTGTGC TCAAGAGGAG CCCTGAGGCC CGAGCCCAAG AGGCCCTGAA CACCATGATT 1020 1021 GCATCTGTGG AGTCATTCCT GCGATACATC AACCGGCAGG TCCGCCAGGG TGAGGAGCAG 1080 1081 GAGAGCTTGG TGGCTGTGGC CCAACGTATT GGGCCCTACG AGGTGCTAGA GCCATCCAGT 1140 1141 GAGGAGGTAG AGAAGAATCT GCGTCCCTTC TCCACCCTGG ACCTGACTTC CCCCATGTTA 1200 1201 GGGGTTTCCC CTGAGCACAC CAGGCAGCTG CTGCTGGAGG GCGCTGTGCG AGTGAAGGAG 1260 1261 GGACGAGAAG CCAAGCTGGA CGTGTACCTG TTCCTCTTCA CTGATGTGCT CCTGGTGACC 1320 1321 AAGCCCCAAC GCAAGGCAGA CAAAGCCAAG GTCATCCGCC CCCCACTCAT GCTGGAGAAG 1380 1381 CTTGTGTTCC GACCACTCCG AGACCCCAGC AGCTTCCTGG TGATCAACCT CACTGAATTC 1440 1441 CAGTGTGTCT CTAGCGCCCT CATTGTGTAC TGTCCCAGTT CCACAGACCG TGCCCAGTGG 1500 1501 CTGGAAAAGA CCCAGAAGGC CCAGGCCACT CTGCAGAAGC TGAAGATAGA AGAGTATGTT 1560 1561 CAGCAGAAGA GGGACCTCCT GGCCCTCTAT CGGGACCGGG ACCGGGACCA GGAGTCCCCG 1620 1621 GGCACCAGAC CCTCCACTCC TTCCCCAGAG GGCTCTCAGG GCAGTGCAGA GGGGAGGGCT 1680 1681 CCTGAGTTCT CAACCATCAT CCCCCACCTG GTGGTAACTG AAGACACAGA TGAAGATGCT 1740 1741 CCCTCAGCAC CAGATGATAC CTCAGACTCT GGCTACAGCA CTTTGATCCC AGGCTCCCCC 1800 1801 AAGGGGCCCC GCTCCCCGCT GAGCCGTCAA CGCCAGCGAG CCCTTCGGCG GGACCCTCGA 1860 1861 CTCACCTTCT CCACCCTGGA CCTCCGAAAT GTTCCTTTGC GCCCCCAACC CCCTAACTCC 1920 1921 CAAGCGCCCC AGCGCCGAAG CGCCCCTGAC CTGCCAGAGG AAGGCATCCA AAGAGGAAGC 1980 1981 AGTCTTCCCA AGGGAGACCC TCCCACCTGG TCTGAGGAAG AAGACGGGAC CTCAGGGGGC 2040 2041 GGGAATGCGG GCGTGGGAAC CCTGCACAGG GCCAGACTTC GGGGGCAGCT CTCCCCCTCC 2100 2101 CCAATCCACG TCGACTCTGC TGGGGAAAGC CCCTGGGACT CTTCAGGGGA TGAAGACGAG 2160 2161 GAGTCCCTCT TCCTGGAGCC CAGCCACGTG CCCTCGCCAC GCCCCCTCCA GGCTGAGGAC 2220 2221 ATGCTCAGGC AGATCCGGGA GGAGCTGGCC AGCCAGAGGG TCGAAGACGC CCCAGAGCCG 2280 2281 CCCAGCGCCA GGCCTCGGAA GCTGACACGG CTGCAGCTGC AGAGGATGCG AGGGCCCCAC 2340 2341 ATCATACAGC TGGACACGCC CCTGTCCACA TCAGAGGTGT GA 2382 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Nol-3859 | Nomascus leucogenys | 83.63 | 0.0 | 1212 |
| LLPS-Cea-3998 | Cercocebus atys | 83.25 | 0.0 | 1187 |
| LLPS-Paa-4178 | Papio anubis | 83.25 | 0.0 | 1186 |
| LLPS-Mal-2888 | Mandrillus leucophaeus | 83.25 | 0.0 | 1188 |
| LLPS-Rhb-0595 | Rhinopithecus bieti | 83.12 | 0.0 | 1184 |
| LLPS-Chs-4698 | Chlorocebus sabaeus | 83.0 | 0.0 | 1184 |
| LLPS-Maf-2017 | Macaca fascicularis | 82.87 | 0.0 | 1182 |
| LLPS-Aon-3897 | Aotus nancymaae | 82.85 | 0.0 | 1187 |
| LLPS-Man-4036 | Macaca nemestrina | 82.75 | 0.0 | 1179 |
| LLPS-Caj-4343 | Callithrix jacchus | 82.63 | 0.0 | 1134 |
| LLPS-Poa-3832 | Pongo abelii | 82.37 | 0.0 | 1193 |
| LLPS-Hos-2669 | Homo sapiens | 82.12 | 0.0 | 1191 |
| LLPS-Pat-1016 | Pan troglodytes | 82.12 | 0.0 | 1192 |
| LLPS-Eqc-2411 | Equus caballus | 82.07 | 0.0 | 1196 |
| LLPS-Pap-0875 | Pan paniscus | 81.99 | 0.0 | 1191 |
| LLPS-Gog-3857 | Gorilla gorilla | 81.49 | 0.0 | 1184 |
| LLPS-Fec-1972 | Felis catus | 81.11 | 0.0 | 1215 |
| LLPS-Ict-1112 | Ictidomys tridecemlineatus | 81.08 | 0.0 | 1184 |
| LLPS-Mam-4322 | Macaca mulatta | 81.01 | 0.0 | 1154 |
| LLPS-Sus-1089 | Sus scrofa | 80.98 | 0.0 | 1177 |
| LLPS-Aim-3284 | Ailuropoda melanoleuca | 80.91 | 0.0 | 1137 |
| LLPS-Otg-1847 | Otolemur garnettii | 80.88 | 0.0 | 1145 |
| LLPS-Orc-2601 | Oryctolagus cuniculus | 79.72 | 0.0 | 1141 |
| LLPS-Bot-0937 | Bos taurus | 78.81 | 0.0 | 1142 |
| LLPS-Urm-4067 | Ursus maritimus | 78.8 | 0.0 | 1119 |
| LLPS-Caf-1013 | Canis familiaris | 78.78 | 0.0 | 1142 |
| LLPS-Mum-4973 | Mus musculus | 78.29 | 0.0 | 1108 |
| LLPS-Myl-3021 | Myotis lucifugus | 78.21 | 0.0 | 1148 |
| LLPS-Mup-0985 | Mustela putorius furo | 78.06 | 0.0 | 1111 |
| LLPS-Tut-1103 | Tursiops truncatus | 77.55 | 0.0 | 1112 |
| LLPS-Ran-2461 | Rattus norvegicus | 76.42 | 0.0 | 1078 |
| LLPS-Mea-0403 | Mesocricetus auratus | 75.56 | 1e-12 | 75.1 |
| LLPS-Fud-3890 | Fukomys damarensis | 74.65 | 0.0 | 999 |
| LLPS-Ova-1361 | Ovis aries | 73.75 | 0.0 | 1020 |
| LLPS-Cap-1138 | Cavia porcellus | 72.81 | 0.0 | 1049 |
| LLPS-Dio-0285 | Dipodomys ordii | 70.62 | 0.0 | 773 |
| LLPS-Sah-1027 | Sarcophilus harrisii | 67.41 | 0.0 | 959 |
| LLPS-Mod-3060 | Monodelphis domestica | 66.79 | 0.0 | 902 |
| LLPS-Asm-1240 | Astyanax mexicanus | 40.05 | 1e-90 | 312 |
| LLPS-Cae-2040 | Caenorhabditis elegans | 29.49 | 2e-49 | 193 |
| LLPS-Gaga-2096 | Gallus gallus | 25.94 | 4e-13 | 77.8 |
| LLPS-Ora-1536 | Ornithorhynchus anatinus | 25.48 | 6e-14 | 80.5 |
| LLPS-Xim-1093 | Xiphophorus maculatus | 25.27 | 3e-13 | 78.2 |
| LLPS-Leo-1245 | Lepisosteus oculatus | 25.07 | 2e-13 | 78.6 |
| LLPS-Xet-0624 | Xenopus tropicalis | 25.07 | 7e-14 | 80.1 |
| LLPS-Anc-1386 | Anolis carolinensis | 24.93 | 4e-13 | 77.8 |
| LLPS-Icp-0487 | Ictalurus punctatus | 24.52 | 3e-13 | 78.2 |
| LLPS-Scf-4145 | Scleropages formosus | 24.52 | 5e-13 | 77.4 |
| LLPS-Gaa-3004 | Gasterosteus aculeatus | 24.52 | 2e-14 | 82.4 |
| LLPS-Pof-3089 | Poecilia formosa | 24.52 | 1e-13 | 79.7 |
| LLPS-Anp-0608 | Anas platyrhynchos | 23.42 | 2e-12 | 75.5 |