LLPS-Lac-a110
CAPZB
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | F-actin-capping protein subunit beta |
| Gene Name: | CAPZB |
| Ensembl Gene: | ENSLACG00000007508.2 |
| Ensembl Protein: | ENSLACP00000008482.1 |
| Organism: | Latimeria chalumnae |
| Taxa ID: | 7897 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLACT00000008550.1 | ENSLACP00000008482.1 |
| Ensembl | ENSLACT00000026082.1 | ENSLACP00000022892.1 |
| UniProt | H3AFR1, H3AFR1_LATCH | |
| GeneBank | AFYH01149498, AFYH01149494, AFYH01149499, AFYH01149502, AFYH01149495, AFYH01149500, AFYH01149493, AFYH01149501, AFYH01149496, AFYH01149497 | |
| RefSeq | XM_006004272.2, XM_006004273.2 | XP_006004334.1, XP_006004335.1 |
| Entrez | 102346314 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL 60 61 LCDYNRDGDS YRSPWSNKYD PPLDDGAMPS ARLRKLEVEA NDAFDQYRDL YFEGGVSSVY 120 121 LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN 180 181 KSGSGTMNLG GSLTRQMEKD ETVSDSSPHI AIIGRLVEDM ENKIRSTLNE IYFGKTKDIV 240 241 NGLRSIDAIP DNQKYKQLQR ELSQVLTQRQ IYIQPDN 277 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTGACC AGCAGCTGGA CTGTGCCTTG GATTTAATGA GGCGTCTGCC TCCCCAGCAG 60 61 ATTGAGAAGA ACCTCAGTGA CCTGATCGAC CTGGTCCCAA GCCTGTGCGA AGATCTGCTG 120 121 TCTTCAGTGG ACCAGCCTCT AAAGATTGCG AGAGATAAGG TGGTGGGAAA GGATTACCTG 180 181 TTGTGTGACT ACAACAGAGA CGGAGACTCG TACAGGTCAC CTTGGAGTAA CAAATATGAC 240 241 CCCCCTTTGG ATGACGGTGC CATGCCATCT GCTCGGCTGC GCAAGCTGGA GGTGGAAGCC 300 301 AACGACGCCT TTGACCAGTA CCGAGATCTG TACTTTGAAG GTGGAGTCTC CTCTGTCTAC 360 361 CTCTGGGATC TGGATCATGG CTTTGCTGGA GTGATCCTCA TCAAGAAGGC TGGAGATGGA 420 421 TCAAAGAAGA TCAAGGGGTG CTGGGACTCC ATTCATGTGG TGGAAGTGCA GGAGAAGTCT 480 481 AGCGGTCGTA CAGCTCATTA CAAGCTGACC TCTACAGTCA TGCTGTGGCT GCAGACCAAC 540 541 AAGAGTGGCT CCGGCACCAT GAACCTAGGA GGCAGCCTTA CCAGACAGAT GGAGAAGGAT 600 601 GAGACTGTGA GCGACTCCTC CCCCCACATA GCTATAATCG GACGGCTGGT AGAGGATATG 660 661 GAAAACAAGA TCAGAAGTAC ACTGAATGAG ATCTACTTTG GAAAGACAAA GGATATTGTC 720 721 AATGGACTGA GATCAATTGA TGCTATACCT GACAACCAAA AGTATAAGCA GTTGCAGAGG 780 781 GAGCTCTCTC AAGTGTTGAC CCAGCGCCAG ATCTACATCC AGCCCGATAA TTAA 834 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | F-actin capping protein complex | |
Molecular Function | Actin binding | |
Biological Process | Actin cytoskeleton organization | |
Biological Process | Barbed-end actin filament capping | |
Biological Process | Muscle cell development | |
Biological Process | Neural crest cell migration |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a119 | Homo sapiens | 3e-180 | 508 | undefined |
| LLPS-Mum-a121 | Mus musculus | 2e-180 | 508 | undefined |