LLPS-Lac-a091
PANX2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pannexin |
| Gene Name: | PANX2, PANX |
| Ensembl Gene: | ENSLACG00000017211.1 |
| Ensembl Protein: | ENSLACP00000019572.1 |
| Organism: | Latimeria chalumnae |
| Taxa ID: | 7897 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Structural component of the gap junctions and the hemichannels. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLACT00000019710.1 | ENSLACP00000019572.1 |
| UniProt | H3BCF1, H3BCF1_LATCH | |
| GeneBank | AFYH01055750, AFYH01055751, AFYH01055749 | |
| RefSeq | XM_005994254.2 | XP_005994316.1 |
| Entrez | 102357778 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQHLIENNPD MATALLAGEK LKELILPGQQ DDKAGSLAAL IVQLKLELPF DRVVTIGTVI 60 61 IPILLVTLVF TKNFAEESIY CYTPHNFTRD QALYARGYCW TELSDAVPGL DASLRPSLFE 120 121 HKFLPYALLA FAGIMYIPAL GWEFLASTRL TSELNFLLQE IDNCYHRAAE GRAPKIEKQI 180 181 QSKGPGITEK EKREIIENAE KEKSPEQNLF EKYLERRGQS NFLAKLYLGR HLFIIFLSII 240 241 PISYLCTYYA TQKQNEFTCI LGEPPDLSSS PDLHVRVNCK LPSVQLQRII TIVDILLLCF 300 301 MNLIILINLI HLFIVRKSNF IFDKLHKVGI KTKKQWQKSQ FCDINILAMF CNENRDHIKS 360 361 LNRLDFITNE SDLMYDNVVR QLLAALAQSN HDVTPTMRDA GIQTIDPSID PADIDSSEQL 420 421 IIKRPRKKIK WISSSNPLPQ PFKEQLANTK VENAKPEKPK PVRRKPVPDN LTAPLLDSSI 480 481 KNAQQSSSLK HESSTATVGE KKHTRHFSLD VHPYVLSNKK PKPEVQETIV IPTSKSQETG 540 541 FLNSEEHALM HASPSVKDST LAGKKVASDI PSLSEACLTV PASGDYHVNN HSHLVTTTVT 600 601 SSIIINQTTS EAKAQFSRNP THPLLNIHTL HEDHEGEDLG LVDNTVVSTT GAGKLLSVHS 660 661 QKQMILPEFE EPVAIMGTGE C 681 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCAACATC TCATAGAAAA CAATCCAGAT ATGGCTACTG CTCTGTTGGC TGGAGAGAAG 60 61 TTGAAGGAGC TGATCCTTCC AGGACAGCAG GATGACAAAG CTGGATCTCT TGCAGCACTG 120 121 ATCGTTCAAC TCAAACTAGA ACTTCCATTT GACAGAGTGG TAACCATAGG GACTGTTATA 180 181 ATTCCTATAT TATTGGTCAC ACTGGTATTC ACCAAGAATT TTGCAGAGGA GTCGATATAC 240 241 TGCTACACGC CCCACAACTT TACCCGTGAC CAAGCCTTGT ATGCCAGAGG ATACTGTTGG 300 301 ACTGAGCTGA GTGATGCAGT GCCAGGTTTA GATGCCAGTC TCCGCCCCTC TTTGTTTGAG 360 361 CACAAGTTTC TTCCTTATGC GCTGCTGGCC TTTGCTGGTA TAATGTACAT TCCTGCTCTG 420 421 GGTTGGGAGT TTCTGGCCTC AACAAGGCTG ACCTCAGAGC TGAACTTTTT GCTTCAGGAA 480 481 ATTGATAATT GTTACCATCG TGCAGCAGAA GGACGTGCAC CAAAAATTGA AAAGCAAATC 540 541 CAGTCGAAAG GGCCAGGGAT TACAGAGAAG GAGAAAAGAG AGATCATAGA GAATGCTGAA 600 601 AAGGAGAAAA GTCCTGAGCA AAACTTGTTT GAAAAATACC TGGAGAGACG AGGACAGAGT 660 661 AATTTTTTGG CCAAACTTTA TCTAGGAAGA CATTTATTCA TTATTTTCTT AAGCATCATC 720 721 CCAATTAGTT ACTTATGCAC TTACTATGCT ACACAGAAGC AAAATGAATT CACATGTATA 780 781 CTAGGAGAAC CACCTGATCT GTCTAGCAGC CCAGATCTAC ATGTCCGTGT CAACTGTAAG 840 841 CTGCCCTCTG TCCAGTTGCA ACGCATTATT ACCATAGTTG ACATCCTTCT TTTGTGTTTC 900 901 ATGAACTTAA TAATTCTCAT CAATTTAATC CACCTCTTTA TAGTTAGGAA ATCCAACTTC 960 961 ATCTTTGATA AATTGCATAA GGTTGGCATA AAGACAAAGA AACAGTGGCA GAAATCACAG 1020 1021 TTTTGTGACA TTAATATTCT TGCTATGTTT TGCAATGAAA ACCGTGACCA CATCAAATCA 1080 1081 CTGAACCGCC TAGACTTTAT CACAAATGAA AGTGACCTGA TGTATGACAA TGTGGTCCGC 1140 1141 CAGCTGCTGG CTGCTTTGGC CCAGTCTAAT CATGATGTTA CCCCGACTAT GCGTGATGCT 1200 1201 GGAATTCAGA CTATTGATCC CAGCATTGAT CCAGCAGATA TAGATTCTAG TGAACAACTT 1260 1261 ATTATTAAAA GGCCTAGGAA AAAAATAAAA TGGATCTCAT CCTCAAATCC ACTTCCTCAA 1320 1321 CCTTTTAAGG AGCAGTTAGC CAACACCAAA GTTGAGAACG CTAAGCCTGA AAAGCCTAAG 1380 1381 CCTGTTAGAA GAAAGCCAGT ACCTGACAAC CTTACAGCTC CTCTTTTAGA TTCCAGTATA 1440 1441 AAAAATGCCC AGCAGTCATC ATCTCTTAAA CATGAGTCCA GTACTGCCAC TGTTGGTGAG 1500 1501 AAAAAGCACA CAAGACATTT TTCTTTAGAT GTTCACCCAT ACGTCTTGAG TAATAAAAAA 1560 1561 CCAAAGCCAG AGGTACAAGA AACAATTGTC ATCCCTACAT CAAAAAGCCA AGAAACTGGA 1620 1621 TTCTTAAACT CAGAAGAACA TGCCTTGATG CATGCTTCCC CTTCTGTTAA AGATAGCACA 1680 1681 TTGGCTGGAA AAAAGGTTGC AAGTGACATC CCAAGTTTGT CAGAGGCATG TCTAACTGTA 1740 1741 CCTGCCTCTG GAGACTACCA TGTGAATAAT CACAGCCATT TAGTAACTAC AACTGTTACA 1800 1801 TCTAGTATAA TTATCAACCA AACAACATCA GAAGCAAAGG CTCAATTTAG CCGTAATCCC 1860 1861 ACACACCCTT TGCTTAATAT TCATACCCTC CATGAAGACC ATGAAGGTGA AGACTTGGGC 1920 1921 CTCGTTGATA ACACTGTGGT TTCCACTACT GGTGCAGGAA AGCTGCTTTC TGTTCATTCT 1980 1981 CAAAAGCAGA TGATTTTGCC AGAATTTGAA GAGCCAGTGG CCATTATGGG CACAGGAGAA 2040 2041 TGCTAA 2046 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasmic vesicle | |
Cellular Component | Gap junction | |
Cellular Component | Integral component of membrane | |
Cellular Component | Plasma membrane | |
Molecular Function | Channel activity | |
Biological Process | Cation transport | |
Biological Process | Positive regulation of interleukin-1 secretion |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a099 | Homo sapiens | 0.0 | 902 | undefined |
| LLPS-Mum-a102 | Mus musculus | 0.0 | 917 | undefined |