LLPS-Lac-3665
KANK2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | KN motif and ankyrin repeat domains 2 |
| Gene Name: | KANK2 |
| Ensembl Gene: | ENSLACG00000008749.1 |
| Ensembl Protein: | ENSLACP00000009924.1 |
| Organism: | Latimeria chalumnae |
| Taxa ID: | 7897 |
| LLPS Type: | Others |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLACT00000010000.1 | ENSLACP00000009924.1 |
| UniProt | H3AJV3, H3AJV3_LATCH | |
| GeneBank | AFYH01054721, AFYH01054722, AFYH01054723 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 LAMTILNNLC ILGKSNPTSP TAFRGKDQDL PYSVETPYGY RLDLDFLKYV DDIEKGHTIK 60 61 KVPIHRRPRY SSLPRGYGYT GSWWTSTESL CSNASMDSRY SSFSYCGRGF YPAYGVENRP 120 121 PLLTSGYNAR VEKTLLDAKR RLEEDQADSA EDRRSRFASL GSLHGSVSGS TSSLSGAGLS 180 181 QSLSKMSSHS NSQSGVSGQY TPMSSGLSTP VSPTPAHLQH VREQMAVALR KLRQLEEQVK 240 241 MIPVLQVKIS VLQEEKRQLS VQLKSQKFLG HTTGFGKPKP RGELYIDIPE EDSDQSGSVF 300 301 SPPLPGSSRS HSGTEIEGSM MQRSLIKSPK KEMRSISVGT GEEMMVRESR PSASVGLGQT 360 361 REVKEVGISV KEHDLGLSSV ATQAEVEHQR QTIEALAAKI SVLEKQLKKA LQELQVAHQK 420 421 LEQQAKEITE REKATKPSTA DAIIMTKLAE VSEVGLQTSN QLELVDQRTM GVQVYISEQP 480 481 TSGTKDYKEV PASPAVPVNL QAPVPQRTEP VESSTVGAPK NEGAYLDQVP VFKTLFTSKT 540 541 EVPYILYKNP EAVETVFPIQ ADHCTEVLHV VKKISLTTET YEDKLKGVDD PAVLEKERRT 600 601 PNKRARGLEE ITKFTSKKIE TGIKSSNNTL IPLEKMISVS ISSEEVSEVL QKPSQMIVLS 660 661 ASSAPVAVEM GGTVLSASAQ QEGPPSPEAN TCSSSVASEQ GSALSTRDAP QPGNLSVRTA 720 721 QLGNVPACSM AQPGKAPAHG VACTWHGLVT GLYAVQHGLV TRPYAVRHGL VTRPYAVQHS 780 781 PVTPRHIAWH GLVRHLTHRA ARSGSTTHMR CGRHSLARHP HTVQHSLVTG PHRMQHGPVT 840 841 CLCVTLNSLS MLSSVEAYKS LFLHTQAGDH DVGPCDFAVD KLERQVPYFI YCCASPETSL 900 901 KSIMKRKDDT AFLDPASRKN LQFVGVNGGY ESTSSDTSSE DSSSENESSE SEYHEANEGP 960 961 PAGHAGQPAE QKPQEMETSD TNNNEKEDSE GEKPTLVTAA AGESASSEEA TEQKFQMSES 1020 1021 LLSASMTLQK YLENPDAVSN MAMKAAYATV LQDWLRISCH KAADQNVVRH HMIVFQAMSP 1080 1081 QLLEFVVNMA DGNGNTALHY TVSHSNFPIV RLLLETGMCN VDKQNKAGYT AIMLTALAAF 1140 1141 RSEGDMETVT QLLHHGNVNA KASQAGQTAL MLAVSHGRID MVKALLAGGA DVNLQDDDGS 1200 1201 TALMCACEHG HVEIVRLLLA VPGCDVTLTD NDGSTALSVA LEANQNEIAM LLHSHMNLTK 1260 1261 ALAPSNPVKI REVSPGFHH 1279 |
| Nucleotide CDS Sequence (FASTA) |
1 CTTGCAATGA CCATTCTCAA TAACTTGTGT ATTTTAGGAA AATCCAATCC AACATCCCCC 60 61 ACAGCCTTTA GAGGCAAAGA CCAAGACCTG CCATATTCGG TGGAGACACC CTATGGTTAC 120 121 CGACTGGATC TTGATTTCTT GAAGTATGTT GATGATATTG AAAAAGGCCA TACCATCAAG 180 181 AAGGTTCCCA TCCATCGTAG GCCAAGGTAC AGCTCCCTCC CACGGGGTTA TGGGTACACT 240 241 GGTTCCTGGT GGACTTCAAC AGAATCTCTC TGCTCCAATG CAAGTATGGA TAGTAGGTAT 300 301 TCTTCTTTCT CCTACTGTGG AAGAGGTTTT TACCCTGCTT ACGGGGTAGA AAACAGACCT 360 361 CCCCTTTTGA CATCTGGATA CAATGCAAGA GTGGAGAAGA CCCTTCTCGA TGCTAAAAGA 420 421 AGGTTGGAAG AGGATCAGGC AGATTCAGCA GAAGACAGGA GATCTAGGTT TGCGAGTTTG 480 481 GGCAGCCTGC ATGGCAGCGT ATCTGGCTCC ACAAGCTCCC TTTCAGGGGC TGGGCTAAGC 540 541 CAGTCGCTTT CCAAGATGTC TTCCCACAGC AATTCCCAGT CGGGAGTCTC TGGCCAGTAC 600 601 ACCCCCATGA GTTCCGGGCT TTCCACCCCT GTGTCTCCGA CTCCTGCCCA CCTGCAACAC 660 661 GTCCGTGAAC AGATGGCAGT GGCCTTGAGG AAGCTGCGCC AACTTGAAGA GCAAGTCAAG 720 721 ATGATACCAG TTCTCCAAGT GAAAATCTCT GTCCTCCAAG AAGAAAAACG TCAGCTGAGT 780 781 GTGCAGCTTA AGAGCCAGAA GTTCCTTGGG CACACCACTG GGTTTGGAAA GCCCAAGCCC 840 841 CGAGGGGAGC TCTATATTGA TATCCCAGAA GAAGACAGTG ACCAAAGTGG CAGCGTTTTC 900 901 TCACCCCCAT TACCAGGTAG CTCACGCTCA CATTCAGGGA CTGAAATTGA AGGCTCCATG 960 961 ATGCAAAGAA GCTTGATCAA ATCACCCAAG AAAGAAATGC GGTCGATAAG TGTTGGTACA 1020 1021 GGGGAAGAGA TGATGGTTAG AGAAAGTAGA CCAAGTGCTA GTGTAGGTTT AGGGCAGACA 1080 1081 CGTGAAGTTA AAGAAGTTGG TATTTCAGTT AAAGAGCACG ACCTAGGGTT ATCGTCGGTA 1140 1141 GCAACTCAAG CAGAAGTAGA GCATCAGCGT CAAACTATCG AAGCACTTGC TGCAAAGATA 1200 1201 TCTGTGTTAG AGAAGCAGTT GAAGAAGGCT TTGCAAGAGC TTCAAGTGGC TCACCAGAAG 1260 1261 TTAGAGCAGC AAGCTAAGGA GATTACAGAG AGAGAAAAAG CCACCAAGCC TTCCACTGCT 1320 1321 GATGCCATTA TTATGACAAA GCTTGCAGAA GTTTCTGAAG TTGGCCTTCA AACATCGAAC 1380 1381 CAACTTGAGC TGGTAGATCA AAGGACCATG GGGGTGCAAG TTTATATTTC AGAACAGCCG 1440 1441 ACTAGTGGAA CAAAGGACTA TAAGGAAGTG CCTGCAAGTC CTGCAGTACC AGTCAACCTT 1500 1501 CAAGCTCCAG TTCCTCAAAG AACAGAACCA GTGGAGTCAA GTACAGTAGG AGCACCCAAG 1560 1561 AATGAGGGGG CTTACCTCGA CCAGGTACCA GTATTTAAGA CTTTGTTTAC CAGTAAAACA 1620 1621 GAAGTACCAT ACATTCTATA CAAGAATCCA GAGGCTGTTG AGACGGTCTT CCCGATTCAA 1680 1681 GCAGATCATT GTACAGAGGT TCTGCACGTT GTGAAGAAGA TCAGCCTGAC AACTGAAACG 1740 1741 TACGAAGACA AACTGAAGGG TGTAGATGAT CCAGCTGTAC TAGAAAAAGA GAGAAGGACA 1800 1801 CCAAATAAAA GGGCAAGAGG TCTGGAAGAA ATTACAAAAT TCACTTCCAA AAAAATAGAG 1860 1861 ACGGGAATAA AGTCCTCAAA CAACACATTA ATACCACTTG AAAAAATGAT ATCCGTATCA 1920 1921 ATAAGCTCCG AGGAGGTCAG TGAAGTTCTT CAGAAACCCA GCCAGATGAT CGTCCTGTCT 1980 1981 GCTTCCAGTG CTCCCGTTGC TGTGGAGATG GGCGGGACCG TGCTGTCGGC TTCCGCCCAG 2040 2041 CAGGAGGGAC CCCCGTCTCC GGAGGCAAAC ACATGTAGTT CGTCTGTGGC AAGCGAACAG 2100 2101 GGCTCGGCGT TGTCCACACG TGATGCACCG CAGCCAGGTA ATCTGTCCGT ACGTACAGCA 2160 2161 CAGCTGGGTA ATGTCCCTGC ATGCAGCATG GCACAGCCTG GTAAAGCCCC TGCACACGGT 2220 2221 GTGGCATGCA CATGGCACGG CCTGGTAACG GGCCTGTATG CAGTGCAGCA TGGCCTGGTA 2280 2281 ACGCGCCCAT ATGCAGTGCG GCACGGCCTG GTAACACGCC CGTATGCAGT GCAGCACAGC 2340 2341 CCGGTAACAC CCCGGCACAT AGCGTGGCAC GGCCTGGTAA GGCACCTAAC ACACCGTGCA 2400 2401 GCACGGTCCG GTAGCACCAC CCACATGCGG TGTGGCCGGC ACAGCCTGGC AAGGCACCCT 2460 2461 CACACGGTAC AACACAGCCT GGTAACGGGC CCGCACAGAA TGCAGCACGG CCCAGTAACG 2520 2521 TGCCTGTGTG TTACGTTGAA TTCATTAAGC ATGTTGAGTT CTGTTGAAGC CTACAAATCC 2580 2581 CTTTTTCTAC ACACGCAGGC GGGAGATCAT GATGTGGGGC CTTGTGACTT TGCAGTGGAT 2640 2641 AAACTTGAAA GGCAGGTTCC ATACTTTATT TATTGCTGTG CTTCTCCTGA GACCAGTTTG 2700 2701 AAGTCCATCA TGAAGCGGAA AGATGACACA GCGTTCCTGG ACCCTGCTTC CAGGAAGAAT 2760 2761 CTCCAGTTTG TGGGAGTCAA TGGAGGTTAC GAATCCACAT CATCGGACAC CAGCTCAGAG 2820 2821 GACAGCTCTT CTGAGAACGA GAGCTCCGAG AGCGAGTACC ATGAGGCCAA CGAGGGGCCG 2880 2881 CCAGCAGGGC ACGCAGGCCA GCCGGCTGAG CAGAAGCCAC AGGAGATGGA AACCAGCGAC 2940 2941 ACAAACAACA ACGAGAAGGA AGACAGTGAG GGCGAGAAGC CAACGCTGGT TACAGCTGCA 3000 3001 GCTGGAGAGA GCGCAAGCAG CGAAGAGGCC ACAGAGCAGA AGTTTCAGAT GAGTGAAAGT 3060 3061 TTGCTTTCTG CTTCGATGAC CCTGCAGAAA TACCTAGAGA ACCCGGATGC CGTCTCCAAC 3120 3121 ATGGCCATGA AAGCAGCTTA TGCCACGGTG CTTCAGGACT GGTTGAGAAT CTCGTGCCAC 3180 3181 AAGGCCGCTG ACCAGAACGT GGTTAGACAT CACATGATTG TGTTCCAGGC CATGTCGCCG 3240 3241 CAGTTACTGG AGTTCGTTGT CAATATGGCA GATGGCAATG GCAACACGGC TCTTCACTAC 3300 3301 ACCGTCTCCC ACTCCAACTT CCCCATCGTC AGGCTGCTGC TAGAAACCGG TATGTGTAAT 3360 3361 GTAGACAAAC AGAACAAAGC CGGATACACC GCCATAATGC TGACTGCACT TGCTGCGTTC 3420 3421 AGGTCAGAGG GTGACATGGA AACAGTGACA CAGCTCCTCC ACCACGGAAA CGTCAATGCC 3480 3481 AAAGCCAGCC AGGCTGGACA GACGGCACTG ATGCTGGCGG TCAGCCACGG TCGGATAGAC 3540 3541 ATGGTGAAGG CGCTGCTGGC AGGAGGGGCA GATGTTAACC TTCAGGACGA TGACGGCTCC 3600 3601 ACCGCACTGA TGTGTGCCTG TGAACACGGG CACGTGGAGA TTGTCCGGCT CCTGCTGGCT 3660 3661 GTTCCGGGCT GTGATGTCAC TCTCACGGAT AACGACGGCA GCACCGCATT GTCAGTTGCA 3720 3721 CTTGAAGCCA ACCAGAATGA GATTGCTATG CTGCTTCACT CCCACATGAA CCTCACGAAA 3780 3781 GCACTTGCTC CATCCAACCC TGTCAAGATA CGAGAAGTAT CTCCAGGATT CCACCAC 3837 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ict-1858 | Ictidomys tridecemlineatus | 85.14 | 3e-28 | 127 |
| LLPS-Caf-2584 | Canis familiaris | 75.56 | 2e-30 | 134 |
| LLPS-Dar-2434 | Danio rerio | 73.77 | 5e-113 | 387 |
| LLPS-Pap-4333 | Pan paniscus | 73.68 | 7e-30 | 132 |
| LLPS-Loa-2584 | Loxodonta africana | 73.4 | 2e-30 | 134 |
| LLPS-Urm-2419 | Ursus maritimus | 73.4 | 1e-30 | 135 |
| LLPS-Aim-3886 | Ailuropoda melanoleuca | 73.4 | 2e-30 | 134 |
| LLPS-Xim-3603 | Xiphophorus maculatus | 73.13 | 1e-105 | 358 |
| LLPS-Pof-1733 | Poecilia formosa | 72.65 | 6e-114 | 388 |
| LLPS-Scm-2159 | Scophthalmus maximus | 72.65 | 2e-113 | 387 |
| LLPS-Icp-0294 | Ictalurus punctatus | 71.6 | 5e-114 | 390 |
| LLPS-Orl-2786 | Oryzias latipes | 70.87 | 8e-113 | 384 |
| LLPS-Mod-3841 | Monodelphis domestica | 67.93 | 5e-91 | 319 |
| LLPS-Orn-1390 | Oreochromis niloticus | 66.79 | 3e-104 | 357 |
| LLPS-Ora-0594 | Ornithorhynchus anatinus | 66.3 | 2e-132 | 436 |
| LLPS-Gaa-2816 | Gasterosteus aculeatus | 66.2 | 3e-102 | 352 |
| LLPS-Xet-3502 | Xenopus tropicalis | 66.09 | 4e-94 | 327 |
| LLPS-Otg-2527 | Otolemur garnettii | 65.6 | 1e-103 | 355 |
| LLPS-Ten-0376 | Tetraodon nigroviridis | 64.91 | 2e-101 | 348 |
| LLPS-Aon-4040 | Aotus nancymaae | 63.75 | 2e-102 | 351 |
| LLPS-Sah-2873 | Sarcophilus harrisii | 63.19 | 3e-134 | 442 |
| LLPS-Myl-2992 | Myotis lucifugus | 62.4 | 2e-104 | 338 |
| LLPS-Leo-0566 | Lepisosteus oculatus | 62.24 | 2e-132 | 432 |
| LLPS-Cap-4675 | Cavia porcellus | 60.74 | 9e-84 | 297 |
| LLPS-Poa-0949 | Pongo abelii | 59.86 | 8e-88 | 310 |
| LLPS-Rhb-1477 | Rhinopithecus bieti | 59.86 | 2e-87 | 309 |
| LLPS-Fec-0391 | Felis catus | 59.72 | 3e-87 | 308 |
| LLPS-Mam-4050 | Macaca mulatta | 59.51 | 3e-87 | 308 |
| LLPS-Eqc-2650 | Equus caballus | 59.51 | 2e-84 | 301 |
| LLPS-Man-3746 | Macaca nemestrina | 59.51 | 5e-87 | 307 |
| LLPS-Paa-3292 | Papio anubis | 59.51 | 5e-87 | 307 |
| LLPS-Mal-1685 | Mandrillus leucophaeus | 59.51 | 6e-87 | 307 |
| LLPS-Cea-1308 | Cercocebus atys | 59.51 | 1e-87 | 307 |
| LLPS-Maf-3229 | Macaca fascicularis | 59.51 | 5e-87 | 307 |
| LLPS-Chs-0006 | Chlorocebus sabaeus | 59.51 | 8e-87 | 306 |
| LLPS-Mup-4323 | Mustela putorius furo | 59.36 | 7e-88 | 310 |
| LLPS-Bot-1613 | Bos taurus | 59.01 | 1e-86 | 306 |
| LLPS-Ova-0124 | Ovis aries | 58.66 | 6e-86 | 304 |
| LLPS-Hos-0003 | Homo sapiens | 58.1 | 7e-82 | 292 |
| LLPS-Pat-2356 | Pan troglodytes | 58.1 | 7e-82 | 292 |
| LLPS-Gog-3896 | Gorilla gorilla | 58.1 | 5e-82 | 293 |
| LLPS-Tar-1452 | Takifugu rubripes | 57.75 | 3e-122 | 407 |
| LLPS-Ran-4443 | Rattus norvegicus | 57.6 | 2e-77 | 278 |
| LLPS-Sus-2716 | Sus scrofa | 57.6 | 1e-81 | 292 |
| LLPS-Mea-2122 | Mesocricetus auratus | 57.6 | 3e-84 | 299 |
| LLPS-Mum-3829 | Mus musculus | 57.24 | 7e-84 | 298 |
| LLPS-Caj-4858 | Callithrix jacchus | 56.89 | 3e-80 | 287 |
| LLPS-Nol-2329 | Nomascus leucogenys | 55.97 | 4e-63 | 236 |
| LLPS-Dio-4013 | Dipodomys ordii | 51.32 | 3e-105 | 351 |
| LLPS-Asm-3001 | Astyanax mexicanus | 49.69 | 1e-102 | 353 |
| LLPS-Orc-1113 | Oryctolagus cuniculus | 40.4 | 3e-08 | 62.8 |
| LLPS-Anc-2764 | Anolis carolinensis | 39.81 | 6e-06 | 55.5 |
| LLPS-Meg-0868 | Meleagris gallopavo | 39.29 | 5e-07 | 58.5 |
| LLPS-Scf-1770 | Scleropages formosus | 38.05 | 2e-06 | 57.0 |
| LLPS-Gaga-1279 | Gallus gallus | 37.76 | 7e-07 | 58.2 |
| LLPS-Cas-1104 | Carlito syrichta | 37.72 | 3e-17 | 92.8 |
| LLPS-Tut-2223 | Tursiops truncatus | 37.72 | 2e-17 | 93.2 |
| LLPS-Fud-0424 | Fukomys damarensis | 37.72 | 2e-17 | 92.8 |
| LLPS-Anp-0535 | Anas platyrhynchos | 37.13 | 6e-17 | 91.7 |
| LLPS-Pes-3487 | Pelodiscus sinensis | 37.06 | 6e-16 | 88.2 |
| LLPS-Tag-2722 | Taeniopygia guttata | 36.59 | 3e-06 | 56.6 |
| LLPS-Fia-1964 | Ficedula albicollis | 36.59 | 3e-06 | 56.2 |
| LLPS-Put-0312 | Puccinia triticina | 35.0 | 5e-16 | 84.3 |
| LLPS-Pug-0778 | Puccinia graminis | 35.0 | 5e-17 | 87.4 |
| LLPS-Dos-1289 | Dothistroma septosporum | 34.57 | 7e-12 | 71.2 |
| LLPS-Drm-1559 | Drosophila melanogaster | 31.74 | 2e-16 | 90.1 |
| LLPS-Crn-1527 | Cryptococcus neoformans | 29.82 | 1e-11 | 70.5 |