• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Kop-0387
PAS_chr1-3_0068

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: 60S acidic ribosomal protein P0
Gene Name: PAS_chr1-3_0068
Ensembl Gene: PAS_chr1-3_0068
Ensembl Protein: CAY67120
Organism: Komagataella pastoris
Taxa ID: 644223
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, OthersPredicted from orthologs(View)

▼ FUNCTION

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCAY67120CAY67120
UniProtC4QV50, C4QV50_KOMPG
GeneBankFN392319CAY67120.1
RefSeqXM_002489359.1XP_002489404.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGGINEKKAE  YFNKLRELLE  SYKSIFIVGV  DNVSSQQMHE  VRQTLRGKAV  ILMGKNTMVR  60
61    KALRDFVEEL  PVFEKLLPFV  RGNIGFVFTN  EDLKTIRDVI  IENRVAAPAR  PGAIAPLDVF  120
121   IPAGNTGMEP  GKTSFFQALG  VPTKISRGTI  EITSDVKVVE  KDSRVGPSEA  QLLNMLNISP  180
181   FTYGLTVVQV  FDDGQVFPAN  ILDITDDELL  SHFTSAISTI  AQISLAAGYP  TLPSVGHSVV  240
241   NHYKNVLAVS  IATDYSFEGS  EAIKDRLANP  EAYAAAAPAA  GEASAGAEET  AAAAEEEDEE  300
301   SEDDDMGFGL  FD  312
Nucleotide CDS Sequence (FASTA)
1     ATGGGAGGTA  TCAACGAAAA  GAAAGCCGAG  TACTTTAACA  AGCTCAGAGA  GCTTTTGGAA  60
61    TCTTACAAGT  CCATCTTTAT  TGTCGGTGTT  GACAATGTCT  CCTCTCAGCA  AATGCACGAG  120
121   GTCAGACAGA  CTCTCCGTGG  TAAAGCTGTG  ATTCTTATGG  GTAAGAACAC  CATGGTCAGA  180
181   AAGGCCTTGA  GAGACTTCGT  CGAGGAGCTC  CCAGTCTTTG  AGAAGCTGTT  GCCTTTCGTC  240
241   AGAGGTAACA  TTGGTTTCGT  CTTCACCAAC  GAGGACTTGA  AAACCATCAG  AGATGTGATC  300
301   ATCGAGAACA  GAGTCGCTGC  CCCAGCCAGA  CCAGGTGCTA  TCGCTCCTTT  GGATGTCTTC  360
361   ATTCCTGCCG  GTAACACTGG  TATGGAACCA  GGTAAGACCT  CTTTCTTCCA  AGCTCTTGGT  420
421   GTCCCAACCA  AGATTTCCAG  AGGTACCATT  GAGATCACCA  GTGATGTTAA  GGTTGTTGAG  480
481   AAAGACTCCA  GAGTTGGTCC  TTCCGAGGCT  CAATTGTTGA  ACATGTTGAA  CATCTCTCCT  540
541   TTCACCTACG  GTTTGACTGT  TGTTCAAGTT  TTCGACGATG  GACAAGTTTT  CCCAGCTAAC  600
601   ATTTTGGACA  TCACCGATGA  CGAGCTGTTG  TCTCACTTCA  CCTCTGCCAT  CTCTACCATT  660
661   GCCCAAATCT  CTTTGGCTGC  TGGTTACCCA  ACTTTGCCAT  CCGTTGGTCA  CTCTGTTGTC  720
721   AACCACTACA  AGAATGTTTT  GGCTGTCTCC  ATTGCTACTG  ACTACTCCTT  TGAGGGTTCT  780
781   GAAGCTATCA  AGGACAGATT  GGCTAACCCT  GAGGCTTACG  CTGCTGCTGC  TCCTGCTGCC  840
841   GGTGAGGCTT  CTGCTGGTGC  CGAGGAGACT  GCTGCCGCTG  CTGAGGAGGA  AGACGAAGAG  900
901   TCTGAGGACG  ACGACATGGG  ATTCGGTTTG  TTTGATTAA  939

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Reference proteome
Ribonucleoprotein
Ribosomal protein

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Ribosome
Biological Process
Ribosome biogenesis

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Yal-0225Yarrowia lipolytica73.234e-136 396
LLPS-Asg-1500Ashbya gossypii72.285e-132 385
LLPS-Sac-1229Saccharomyces cerevisiae71.151e-131 384
LLPS-Mao-1623Magnaporthe oryzae70.044e-136 395
LLPS-Scs-0609Sclerotinia sclerotiorum69.299e-125 367
LLPS-Cog-0204Colletotrichum gloeosporioides68.547e-121 358
LLPS-Cogr-1093Colletotrichum graminicola68.545e-121 357
LLPS-Coo-1016Colletotrichum orbiculare68.542e-122 361
LLPS-Nec-0390Neurospora crassa68.547e-124 364
LLPS-Fus-0299Fusarium solani68.162e-121 358
LLPS-Phn-1019Phaeosphaeria nodorum68.161e-123 363
LLPS-Ved-1460Verticillium dahliae67.792e-112 335
LLPS-Gag-1382Gaeumannomyces graminis67.731e-136 397
LLPS-Lem-1247Leptosphaeria maculans67.422e-122 361
LLPS-Map-0729Magnaporthe poae67.419e-137 397
LLPS-Blg-0726Blumeria graminis67.163e-121 358
LLPS-Asc-0367Aspergillus clavatus67.092e-125 368
LLPS-Fuo-1124Fusarium oxysporum67.042e-121 358
LLPS-Pytr-1279Pyrenophora triticirepentis67.042e-118 351
LLPS-Fuv-0491Fusarium verticillioides67.042e-121 358
LLPS-Pyt-0936Pyrenophora teres67.042e-121 358
LLPS-Crn-1413Cryptococcus neoformans66.998e-124 364
LLPS-Asn-1202Aspergillus nidulans66.353e-121 358
LLPS-Asni-0664Aspergillus niger66.296e-122 360
LLPS-Scj-1202Schizosaccharomyces japonicus66.294e-130 380
LLPS-Asfu-0801Aspergillus fumigatus66.139e-124 364
LLPS-Tum-1102Tuber melanosporum65.939e-36 132
LLPS-Trr-1171Trichoderma reesei65.922e-118 353
LLPS-Trv-1231Trichoderma virens65.924e-118 350
LLPS-Zyt-0959Zymoseptoria tritici65.51e-118 351
LLPS-Beb-0947Beauveria bassiana65.172e-121 358
LLPS-Usm-1215Ustilago maydis64.862e-118 350
LLPS-Dos-0112Dothistroma septosporum64.791e-113 338
LLPS-Ast-1355Aspergillus terreus64.746e-120 354
LLPS-Abg-1350Absidia glauca64.298e-60 195
LLPS-Nef-0716Neosartorya fischeri64.222e-120 356
LLPS-Asf-1366Aspergillus flavus63.93e-120 355
LLPS-Aso-1186Aspergillus oryzae63.93e-120 355
LLPS-Scp-1436Schizosaccharomyces pombe63.848e-128 374
LLPS-Xim-1443Xiphophorus maculatus62.769e-52 177
LLPS-Pug-0348Puccinia graminis62.553e-113 337
LLPS-Mel-1238Melampsora laricipopulina62.172e-113 338
LLPS-Put-0606Puccinia triticina61.84e-113 337
LLPS-Spr-0427Sporisorium reilianum61.664e-117 347
LLPS-Scc-1381Schizosaccharomyces cryophilus61.396e-120 354
LLPS-Miv-1398Microbotryum violaceum59.943e-114 340
LLPS-Meg-3106Meleagris gallopavo58.224e-84 261
LLPS-Orc-1934Oryctolagus cuniculus58.03e-96 293
LLPS-Lac-2913Latimeria chalumnae57.982e-98 300
LLPS-Chs-2695Chlorocebus sabaeus57.713e-85 265
LLPS-Scf-1025Scleropages formosus57.691e-98 302
LLPS-Fia-0215Ficedula albicollis57.597e-98 298
LLPS-Tag-3506Taeniopygia guttata57.597e-98 298
LLPS-Anc-2214Anolis carolinensis57.598e-98 298
LLPS-Dio-4024Dipodomys ordii57.597e-98 298
LLPS-Orn-2476Oreochromis niloticus57.527e-97 296
LLPS-Ora-3149Ornithorhynchus anatinus57.317e-99 299
LLPS-Pes-1673Pelodiscus sinensis57.23e-97 296
LLPS-Rhb-4742Rhinopithecus bieti57.22e-97 297
LLPS-Mod-1462Monodelphis domestica57.26e-97 296
LLPS-Fec-3630Felis catus57.22e-97 297
LLPS-Hos-4125Homo sapiens57.22e-97 297
LLPS-Pat-3815Pan troglodytes57.22e-97 297
LLPS-Urm-1311Ursus maritimus57.22e-97 297
LLPS-Pap-1971Pan paniscus57.22e-97 297
LLPS-Man-2874Macaca nemestrina57.22e-97 297
LLPS-Gaga-2078Gallus gallus57.22e-97 298
LLPS-Cas-1130Carlito syrichta57.22e-97 297
LLPS-Nol-3184Nomascus leucogenys57.22e-97 297
LLPS-Cap-3238Cavia porcellus57.22e-97 297
LLPS-Eqc-2907Equus caballus57.22e-97 297
LLPS-Poa-0915Pongo abelii57.22e-97 297
LLPS-Caf-3853Canis familiaris57.22e-97 297
LLPS-Mam-3157Macaca mulatta57.29e-98 298
LLPS-Gog-0607Gorilla gorilla57.22e-97 297
LLPS-Caj-1117Callithrix jacchus57.22e-97 297
LLPS-Icp-2561Ictalurus punctatus57.25e-97 296
LLPS-Asm-1968Astyanax mexicanus57.21e-95 292
LLPS-Maf-2308Macaca fascicularis57.29e-98 298
LLPS-Sus-2093Sus scrofa57.21e-97 298
LLPS-Aon-1155Aotus nancymaae57.22e-97 297
LLPS-Orl-1302Oryzias latipes57.22e-95 292
LLPS-Mup-0782Mustela putorius furo57.22e-97 297
LLPS-Myl-3276Myotis lucifugus57.23e-97 296
LLPS-Ova-1467Ovis aries57.21e-97 298
LLPS-Mal-3162Mandrillus leucophaeus57.22e-97 297
LLPS-Paa-2693Papio anubis57.22e-97 297
LLPS-Tut-0641Tursiops truncatus57.21e-96 295
LLPS-Bot-2116Bos taurus57.22e-97 297
LLPS-Leo-2277Lepisosteus oculatus56.922e-97 297
LLPS-Otg-3801Otolemur garnettii56.815e-97 296
LLPS-Ict-1675Ictidomys tridecemlineatus56.811e-96 295
LLPS-Mum-4538Mus musculus56.812e-96 294
LLPS-Sah-1520Sarcophilus harrisii56.813e-96 294
LLPS-Cea-1980Cercocebus atys56.812e-96 295
LLPS-Ran-3567Rattus norvegicus56.815e-97 296
LLPS-Aim-1730Ailuropoda melanoleuca56.814e-96 294
LLPS-Anp-2851Anas platyrhynchos56.625e-48 164
LLPS-Dar-3254Danio rerio56.546e-97 296
LLPS-Ten-0507Tetraodon nigroviridis56.546e-95 291
LLPS-Loa-4488Loxodonta africana56.422e-96 295
LLPS-Fud-1799Fukomys damarensis56.423e-96 294
LLPS-Pof-1077Poecilia formosa56.391e-98 300
LLPS-Cis-1451Ciona savignyi56.152e-93 286
LLPS-Cae-0216Caenorhabditis elegans56.034e-98 299
LLPS-Cii-0328Ciona intestinalis55.771e-89 277
LLPS-Scm-3253Scophthalmus maximus55.239e-97 295
LLPS-Tar-0918Takifugu rubripes55.231e-91 282
LLPS-Xet-2929Xenopus tropicalis55.081e-102 310
LLPS-Gaa-2874Gasterosteus aculeatus55.051e-94 290
LLPS-Drm-1392Drosophila melanogaster54.234e-98 299
LLPS-Php-1895Physcomitrella patens49.621e-82 259
LLPS-Mea-3349Mesocricetus auratus49.015e-36 135
LLPS-Chc-0816Chondrus crispus48.848e-84 263
LLPS-Tru-2069Triticum urartu48.154e-62 204
LLPS-Phv-2146Phaseolus vulgaris47.732e-85 266
LLPS-Thc-0164Theobroma cacao47.735e-86 268
LLPS-Vir-1486Vigna radiata47.731e-85 267
LLPS-Gor-1798Gossypium raimondii47.353e-87 271
LLPS-Via-2177Vigna angularis47.199e-84 263
LLPS-Sem-1982Selaginella moellendorffii47.013e-86 268
LLPS-Pot-2804Populus trichocarpa46.974e-85 266
LLPS-Met-1365Medicago truncatula46.979e-83 259
LLPS-Chr-1446Chlamydomonas reinhardtii46.862e-82 258
LLPS-Cym-1013Cyanidioschyzon merolae46.645e-82 258
LLPS-Prp-1859Prunus persica46.591e-83 262
LLPS-Cus-1975Cucumis sativus46.592e-86 269
LLPS-Arl-2653Arabidopsis lyrata46.597e-82 257
LLPS-Gas-1242Galdieria sulphuraria46.567e-81 256
LLPS-Osl-0758Ostreococcus lucimarinus46.448e-80 252
LLPS-Nia-0219Nicotiana attenuata46.211e-83 262
LLPS-Art-2855Arabidopsis thaliana46.211e-81 256
LLPS-Hea-2727Helianthus annuus46.212e-81 256
LLPS-Sol-0640Solanum lycopersicum46.041e-82 259
LLPS-Mae-2016Manihot esculenta45.833e-83 261
LLPS-Viv-0057Vitis vinifera45.837e-84 263
LLPS-Mua-1466Musa acuminata45.833e-83 261
LLPS-Amt-1755Amborella trichopoda45.454e-83 261
LLPS-Orp-0972Oryza punctata45.454e-77 245
LLPS-Zem-1629Zea mays45.456e-77 244
LLPS-Coc-2279Corchorus capsularis45.456e-82 258
LLPS-Brn-1621Brassica napus45.453e-80 253
LLPS-Orbr-0333Oryza brachyantha45.086e-77 244
LLPS-Brr-1404Brassica rapa45.081e-78 249
LLPS-Ors-0658Oryza sativa45.081e-76 244
LLPS-Bro-2055Brassica oleracea45.088e-80 252
LLPS-Orr-0367Oryza rufipogon45.081e-76 244
LLPS-Orm-1189Oryza meridionalis45.081e-76 244
LLPS-Orni-0910Oryza nivara45.081e-76 244
LLPS-Glm-1828Glycine max45.082e-82 259
LLPS-Orb-2305Oryza barthii45.081e-76 244
LLPS-Sei-2264Setaria italica45.086e-77 244
LLPS-Orgl-0037Oryza glumaepatula45.081e-76 244
LLPS-Hov-1528Hordeum vulgare44.943e-81 256
LLPS-Brd-0132Brachypodium distachyon44.791e-79 253
LLPS-Org-1785Oryza glaberrima44.79e-76 241
LLPS-Dac-1830Daucus carota44.74e-75 240
LLPS-Ori-0403Oryza indica44.79e-76 241
LLPS-Tra-2902Triticum aestivum44.75e-82 258
LLPS-Lep-1745Leersia perrieri44.76e-76 242
LLPS-Sot-1151Solanum tuberosum44.324e-74 237
LLPS-Sob-0969Sorghum bicolor43.942e-81 256