• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ict-2170
HOOK3

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: HOOK3
Ensembl Gene: ENSSTOG00000011611.3
Ensembl Protein: ENSSTOP00000010424.3
Organism: Ictidomys tridecemlineatus
Taxa ID: 43179
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFNVESLERV  ELCESLLTWI  QTFNVDTPCQ  TVEDLTNGVV  MAQVLQKIDP  AYFDENWLNR  60
61    IKTEVGDNWR  LKISNLKKIL  KGILDYNHEI  LGQQINDFTL  PDVNLIGEHS  DAAELGRMLQ  120
121   LILGCAVNCE  QKQEYIQAIM  MMEESVQHVV  MTAIQELMSK  ESPVSSGNDA  YVDLDRQLKK  180
181   TTEELNEALS  AKEEIAQRCH  ELDMQVAALQ  EEKSSLLAEN  QILMERLNQS  DSIEDPNSPA  240
241   GRRHLQLQTQ  LEQLQEETFR  LEAAKDDYRI  RCEELEKEIS  ELRQQNDELT  TLADEAQSLK  300
301   DEIDVLRHSS  DKVSKLEGQV  ESYKKKLEDL  GDLRRQVKLL  EEKNTMYMQN  TVSLEEELRK  360
361   ANAARSQLET  YKRQVVELQN  RLSEESKKAD  KLDFEYKRLK  EKVDSLQKEK  DRLRTERDSL  420
421   KETIEELRCV  QAQEGQLTTQ  GLMPLGSQES  SDSLAAEIIT  PEIREKLIRL  QHENRMLKIN  480
481   QEGSDNEKIA  LLQSLLDDAN  LRKNELETEN  RLVNQRLLEV  QSQVEELQKS  LQDQGSKAED  540
541   SVLLKKKLEE  HLEKLHEANN  ELQKKRAIIE  DLEPRFNNSS  LKIEELQEAL  RKKEEEMKQM  600
601   EERYKKYLEK  AKSVIRTLDP  KQNQGAAPEI  QALKNQLQER  DRLFHSLEKE  YEKTKSQREM  660
661   EEKCIVSAWY  NMGMTLHKKA  AEDRLASTGS  GQSFLARQRQ  ATSTRRSYPG  HVQPATAR  718
Nucleotide CDS Sequence (FASTA)
1     ATGTTCAACG  TGGAGTCGTT  GGAGCGGGTG  GAGCTGTGCG  AGAGCCTTCT  TACTTGGATC  60
61    CAGACATTTA  ACGTGGATAC  ACCATGCCAG  ACCGTGGAAG  ATTTAACGAA  TGGGGTTGTG  120
121   ATGGCCCAGG  TTCTCCAAAA  GATAGATCCT  GCATATTTTG  ATGAAAATTG  GCTAAACAGA  180
181   ATCAAAACTG  AAGTGGGAGA  TAATTGGAGG  CTAAAGATTA  GCAATTTAAA  GAAAATATTA  240
241   AAAGGAATCC  TAGATTACAA  TCATGAGATT  TTGGGACAAC  AGATTAATGA  CTTTACCCTT  300
301   CCTGATGTGA  ACCTTATTGG  AGAGCATTCT  GATGCAGCAG  AGCTTGGAAG  GATGCTCCAA  360
361   CTCATTTTAG  GCTGTGCTGT  GAACTGTGAA  CAGAAGCAAG  AGTACATCCA  AGCCATTATG  420
421   ATGATGGAGG  AATCTGTTCA  ACATGTTGTC  ATGACAGCCA  TTCAAGAGCT  AATGAGTAAA  480
481   GAGTCTCCTG  TCTCTTCTGG  GAATGATGCC  TATGTTGACC  TTGATCGCCA  GTTGAAGAAA  540
541   ACTACAGAAG  AATTAAATGA  AGCTTTGTCA  GCAAAGGAAG  AAATTGCTCA  AAGATGCCAT  600
601   GAATTAGATA  TGCAGGTTGC  AGCATTGCAA  GAGGAGAAAA  GTAGTTTATT  GGCAGAGAAT  660
661   CAGATATTAA  TGGAAAGACT  CAATCAATCT  GATTCCATAG  AAGATCCCAA  CAGTCCAGCA  720
721   GGAAGAAGGC  ATTTGCAACT  CCAAACTCAA  TTAGAACAGC  TACAAGAAGA  AACATTCAGA  780
781   CTAGAAGCAG  CCAAAGATGA  TTATCGAATA  CGCTGTGAAG  AGTTAGAAAA  GGAAATCTCT  840
841   GAACTTCGGC  AACAGAATGA  TGAATTAACT  ACTTTGGCAG  ACGAAGCTCA  GTCTCTAAAA  900
901   GATGAAATAG  ATGTTCTTAG  ACATTCTTCT  GATAAAGTAT  CTAAACTAGA  AGGTCAAGTG  960
961   GAATCTTATA  AAAAGAAGCT  GGAAGACCTT  GGTGATTTGA  GGCGGCAGGT  TAAACTCTTA  1020
1021  GAAGAGAAGA  ATACCATGTA  TATGCAGAAC  ACTGTCAGTC  TAGAGGAAGA  GTTAAGAAAG  1080
1081  GCCAATGCAG  CACGAAGTCA  ACTTGAGACG  TATAAGAGAC  AGGTAGTAGA  ACTGCAAAAT  1140
1141  AGATTATCTG  AAGAATCAAA  GAAAGCAGAT  AAATTAGACT  TTGAATATAA  GCGGCTAAAA  1200
1201  GAAAAAGTTG  ATAGTCTTCA  AAAGGAAAAG  GATAGATTAA  GAACAGAAAG  GGATTCTCTG  1260
1261  AAGGAAACTA  TTGAAGAGCT  TCGTTGTGTG  CAGGCTCAGG  AAGGACAGCT  CACCACTCAA  1320
1321  GGATTAATGC  CTTTGGGCAG  TCAAGAATCT  TCAGATAGCC  TCGCAGCAGA  GATTATTACT  1380
1381  CCTGAAATCA  GGGAGAAACT  TATTCGTCTT  CAGCATGAGA  ATAGAATGCT  AAAAATTAAT  1440
1441  CAAGAGGGTT  CAGACAATGA  AAAAATTGCC  TTATTGCAGA  GCCTTTTAGA  TGACGCAAAT  1500
1501  CTACGCAAGA  ATGAACTGGA  GACAGAGAAC  AGGCTTGTGA  ATCAAAGACT  TCTAGAAGTA  1560
1561  CAGTCACAAG  TTGAAGAACT  GCAGAAATCT  TTACAAGATC  AAGGCTCAAA  AGCAGAAGAT  1620
1621  TCAGTTCTTC  TAAAAAAGAA  GCTTGAAGAA  CATCTAGAGA  AGCTTCATGA  AGCTAATAAT  1680
1681  GAATTGCAAA  AGAAGAGAGC  CATTATTGAA  GATCTTGAGC  CAAGATTTAA  CAATAGCTCC  1740
1741  TTAAAAATTG  AAGAATTACA  AGAAGCATTA  CGGAAGAAAG  AAGAGGAAAT  GAAGCAAATG  1800
1801  GAAGAACGAT  ATAAAAAATA  TTTAGAGAAA  GCCAAAAGTG  TTATCCGTAC  TTTAGATCCT  1860
1861  AAACAGAATC  AAGGAGCAGC  ACCAGAAATA  CAAGCTCTTA  AAAATCAACT  GCAGGAAAGA  1920
1921  GACAGACTAT  TTCACTCATT  GGAGAAAGAA  TACGAGAAAA  CGAAGAGTCA  AAGAGAGATG  1980
1981  GAGGAGAAAT  GTATTGTCAG  TGCCTGGTAC  AATATGGGAA  TGACTCTGCA  CAAAAAGGCG  2040
2041  GCTGAAGATA  GACTAGCTAG  TACAGGTTCA  GGGCAGTCAT  TTCTAGCTAG  GCAAAGACAA  2100
2101  GCAACCAGCA  CAAGAAGATC  TTATCCAGGC  CATGTTCAAC  CAGCCACAGC  AAGGTAG  2157

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-3313Ursus maritimus99.260.01250
LLPS-Fud-3771Fukomys damarensis98.860.01291
LLPS-Fec-4002Felis catus98.750.01330
LLPS-Mam-2584Macaca mulatta98.710.01280
LLPS-Mup-0413Mustela putorius furo98.670.01239
LLPS-Pat-2294Pan troglodytes98.610.01328
LLPS-Hos-4422Homo sapiens98.610.01328
LLPS-Caf-1909Canis familiaris98.610.01329
LLPS-Poa-1985Pongo abelii98.610.01323
LLPS-Cap-4602Cavia porcellus98.610.01328
LLPS-Rhb-0909Rhinopithecus bieti98.570.01136
LLPS-Aon-2016Aotus nancymaae98.470.01325
LLPS-Nol-0937Nomascus leucogenys98.470.01326
LLPS-Eqc-0137Equus caballus98.470.01319
LLPS-Chs-3793Chlorocebus sabaeus98.370.01226
LLPS-Maf-4324Macaca fascicularis98.330.01316
LLPS-Cea-3141Cercocebus atys98.330.01321
LLPS-Man-2112Macaca nemestrina98.330.01321
LLPS-Orc-1262Oryctolagus cuniculus98.190.01316
LLPS-Caj-4853Callithrix jacchus98.050.01318
LLPS-Mea-2886Mesocricetus auratus98.050.01322
LLPS-Loa-1950Loxodonta africana98.050.01320
LLPS-Sus-4287Sus scrofa97.930.01078
LLPS-Myl-0750Myotis lucifugus97.870.01290
LLPS-Otg-2396Otolemur garnettii97.780.01315
LLPS-Bot-0977Bos taurus97.710.01080
LLPS-Mum-0849Mus musculus97.490.01313
LLPS-Sah-3659Sarcophilus harrisii97.490.01229
LLPS-Aim-3121Ailuropoda melanoleuca97.210.01297
LLPS-Cas-1655Carlito syrichta96.910.01284
LLPS-Pap-0038Pan paniscus96.390.01292
LLPS-Mal-2830Mandrillus leucophaeus96.290.01240
LLPS-Mod-3405Monodelphis domestica96.240.01291
LLPS-Tag-2685Taeniopygia guttata95.820.01282
LLPS-Ova-1227Ovis aries95.680.01261
LLPS-Dio-3572Dipodomys ordii95.680.01272
LLPS-Anp-2404Anas platyrhynchos94.660.01209
LLPS-Ora-1232Ornithorhynchus anatinus94.040.01263
LLPS-Gog-1606Gorilla gorilla94.010.0 969
LLPS-Anc-0661Anolis carolinensis94.010.01274
LLPS-Gaga-3927Gallus gallus93.310.01237
LLPS-Fia-2919Ficedula albicollis92.680.01233
LLPS-Pes-3779Pelodiscus sinensis92.390.01238
LLPS-Paa-4286Papio anubis91.360.01192
LLPS-Xet-1867Xenopus tropicalis90.290.01194
LLPS-Lac-3371Latimeria chalumnae88.290.01181
LLPS-Leo-2649Lepisosteus oculatus85.50.01170
LLPS-Scf-2247Scleropages formosus84.940.01144
LLPS-Xim-2457Xiphophorus maculatus82.340.01110
LLPS-Pof-1777Poecilia formosa82.310.01108
LLPS-Scm-1997Scophthalmus maximus82.030.01109
LLPS-Asm-3475Astyanax mexicanus81.60.01123
LLPS-Orn-1547Oreochromis niloticus81.480.01102
LLPS-Icp-1400Ictalurus punctatus81.360.01046
LLPS-Ten-1960Tetraodon nigroviridis80.250.01083
LLPS-Gaa-0168Gasterosteus aculeatus80.20.01065
LLPS-Orl-3249Oryzias latipes79.540.01095
LLPS-Meg-1373Meleagris gallopavo78.390.0 952
LLPS-Tut-0698Tursiops truncatus58.190.0 696
LLPS-Dar-2510Danio rerio51.962e-89 295
LLPS-Cii-1884Ciona intestinalis50.192e-164 492
LLPS-Ran-0117Rattus norvegicus48.310.0 553
LLPS-Pug-1507Puccinia graminis34.651e-1379.0
LLPS-Drm-1721Drosophila melanogaster33.856e-96 318
LLPS-Abg-0517Absidia glauca29.431e-34 145
LLPS-Blg-0343Blumeria graminis29.332e-0862.4
LLPS-Mel-1538Melampsora laricipopulina28.914e-1996.7
LLPS-Tum-1460Tuber melanosporum27.81e-1172.4
LLPS-Usm-1073Ustilago maydis26.721e-25 117
LLPS-Miv-1476Microbotryum violaceum26.61e-31 136
LLPS-Tar-1033Takifugu rubripes26.582e-1997.8
LLPS-Spr-1025Sporisorium reilianum24.412e-29 129
LLPS-Asf-1267Aspergillus flavus24.081e-1894.7
LLPS-Aso-0125Aspergillus oryzae24.081e-1894.7
LLPS-Nef-1601Neosartorya fischeri23.851e-1585.5
LLPS-Crn-0830Cryptococcus neoformans23.73e-20 100
LLPS-Asfu-1005Aspergillus fumigatus23.631e-1585.5
LLPS-Asc-0348Aspergillus clavatus23.463e-1274.3
LLPS-Asni-1229Aspergillus niger23.452e-1171.6
LLPS-Ast-1394Aspergillus terreus22.931e-1378.6