LLPS-Icp-4064
gli3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | transcriptional activator GLI3 isoform X1 |
| Gene Name: | gli3 |
| Ensembl Gene: | ENSIPUG00000003729.1 |
| Ensembl Protein: | ENSIPUP00000005345.1 |
| Organism: | Ictalurus punctatus |
| Taxa ID: | 7998 |
| LLPS Type: | Client |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle, Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSIPUT00000005582.1 | ENSIPUP00000005345.1 |
| Ensembl | ENSIPUT00000005593.1 | ENSIPUP00000005356.1 |
| Ensembl | ENSIPUT00000005618.1 | ENSIPUP00000005378.1 |
| UniProt | A0A2D0PR48, A0A2D0PR48_ICTPU | |
| RefSeq | , XM_017453559.1 | , XP_017309048.1, XP_017309048.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 METQSQASST AEKKKRAETI VATKRSSLTR TEISEKAVAS STTSNEDENT SSPYHRERCN 60 61 VISGQLPVPG QGSVAAKLSD EPSTSTEERP LLVKKELQTS LPYLPEHTLP YRGTLFAMDP 120 121 RNSYLDPHYT PAHFFPGFHP PVPVDDRHTQ GRYIYEPSPV PPLHVPPVLA GSPAFSDISV 180 181 IRIPPHRNSS GIGVDSTFSP PHPYINPYMD YIRSIHSSPS LSMISAARGL SPADAPHTGL 240 241 TTAEYYHQMA LLAGHRSPYA DIIPSTMSTT GSGTNALHME YLQALEASSR FPSPRLLARQ 300 301 GRKRPLPGSP HSDSSFDFQA MIRKSPNSLV SILNSTRPSS STSGSYGHLS AGTISPALNF 360 361 AYPPTPVALQ MHQQLIGRPP GIVASAFGHS PPLIHPGPAF TTQRPIAGIT PSGPGPTERF 420 421 TSSTDIQSKP TSESAVTSTG DPMHHKRSKL KPDDEPPSPG AVSVQDHPDG MTLVKEEEDK 480 481 EDGKQEPEVV YETNCHWENC CREFDTQEQL VHHINNDHIH GEKKEFVCRW EECSREQKPF 540 541 KAQYMLVVHM RRHTGEKPHK CTFEGCSKAY SRLENLKTHL RSHTGEKPYV CEHEGCNKAF 600 601 SNASDRAKHQ NRTHSNEKPY VCKIPGCTKR YTDPSSLRKH VKTVHGPEAH VTKKQRGDVF 660 661 PRPPAHPREP GANGQGRSSK LQCPFEAFPD QREYNHATSK QDECLQVKSI KTEKPMTSQP 720 721 SPGSQSSCSS GQSPTSSHLS RGVQLAVNTI GLVGEEVVED QEFEVEDEEK DTEVVEEESP 780 781 IMVSTVSTAT ATAATVALQP CRSLGQPLRW MEQVKMERLR QVNGGTSRLG HLSPTAPSKG 840 841 HSLPSLTMKG LCTVRSTCGG APVPQPPLHP EPSSTELTML SLLRDRRDSS GSATSSAYLS 900 901 SSRRSSGISP CFSSRRSSQA SRSEHSQQRQ LHNLSATDSY DPISTDASRR SSDASQCGGG 960 961 GGSGGVVLGR SWGSRSGGVG GGGMGSRGVL NLTPAQHYHL KATYAAATGG PPPTPLPKLE 1020 1021 QVSYKIQMTM ARDVKGTNQL PLPSLFRPRC SSDGSSHGQS SHIRYRWRRL YPGEGPGNSN 1080 1081 RRASDPLMPR DQNNTGNPQI QRFGSQNNMD QLPPLVGNNV SSGVGKSTNH QNDTNLVDII 1140 1141 QSGQLSPFPP SIMEQSALEA LAIEHDGALL FKDDGCLLGD HKAPCSQQNG INSQFHRNDF 1200 1201 TQNSKEVQKV QNPSQDHGAQ EAQNPRKDSL PIQWNEVSSG STDFSSPWEP WRCEQWPNHI 1260 1261 NTVGLPFGHF ENMIVQQQLP SYFTDQRHPN QRGSVQQITE LTDGHIYPNQ HRQGSNPSQH 1320 1321 RSCRMSQGVS VETTQRNCNG TSSSTYNFGQ QNCQNALGLI QPSSVHQATQ PQTQPQTQQL 1380 1381 QQSHEIPCQT SGNLLQQGTV KPSTSHISVL SLQPASQHVD QDPSQPQQYS TQQIIGSHNA 1440 1441 QSYKSFTKGN ISNRSLANHV SGLKLEIEDQ LQPNSCSSMQ QQQIFEQWFD PAKSSIFRAQ 1500 1501 HCQMESFKIE TGISCESLED VLSPGADQVT STVESSPDGS VRDVGIHFFS ILDDSLDQGS 1560 1561 LVSDVISPSV VHDLSQTSSC LTTPNLSAVL HSLPLGTTNM AIGDMSSFLT TLAEESKFLA 1620 1621 IMQ 1623 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAAACAC AGTCCCAGGC CAGTTCCACA GCAGAGAAGA AAAAGAGGGC AGAGACCATC 60 61 GTGGCAACCA AGAGATCCTC CTTGACCCGA ACTGAGATCA GCGAGAAGGC TGTGGCTTCC 120 121 AGCACTACAT CCAACGCTCC GGCTCATTTC TTCCCTGGAT TCCACCCTCC TGTGCCAGTT 180 181 GACGACAGAC ACACACAGGG ACGTTACATC TACGAGCCCT CTCCAGTGCC ACCGCTCCAT 240 241 GTGCCTCCTG TATTGGCAGG CAGCCCTGCA TTTTCTGATA TCTCTGTCAT CAGAATCCCA 300 301 CCCCACCGGA ATTCTTCAGG CATAGGAGTG GATTCGACCT TTAGCCCCCC ACACCCATAC 360 361 ATCAACCCAT ACATGGACTA CATCCGCTCC ATTCATAGCA GCCCCTCTCT TTCTATGATC 420 421 TCTGCAGCTA GGGGACTCAG CCCTGCAGAT GCCCCACACA CTGGTTTGAC CACAGCAGAA 480 481 TACTACCATC AAATGGCACT GCTTGCAGGT CACCGTAGCC CCTATGCTGA CATCATTCCC 540 541 TCTACCATGT CTACTACTGG ATCAGGGACC AATGCTTTGC ACATGGAATA CCTCCAGGCT 600 601 CTGGAAGCAA GTTCTCGCTT TCCCAGTCCG AGACTCCTTG CTCGTCAGGG CAGGAAGCGC 660 661 CCCCTTCCTG GCTCACCACA CTCAGACTCA AGTTTTGATT TTCAAGCCAT GATCCGGAAA 720 721 TCACCAAATT CCCTGGTGAG CATCCTGAAC AGCACGCGGC CCAGCTCATC GACCAGTGGA 780 781 TCCTACGGCC ATCTGTCTGC TGGTACTATC AGTCCTGCAC TGAATTTTGC CTACCCTCCC 840 841 ACCCCAGTGG CACTGCAAAT GCATCAGCAG CTAATTGGCC GGCCTCCAGG CATTGTGGCT 900 901 TCTGCTTTCG GGCATAGTCC CCCTCTCATC CACCCTGGCC CTGCCTTCAC TACTCAGAGA 960 961 CCCATAGCAG GCATCACCCC CTCAGGACCT GGGCCCACAG AGCGCTTCAC TAGCTCCACT 1020 1021 GACATTCAAA GTAAACCTAC CAGTGAGTCA GCAGTGACCA GCACAGGAGA CCCCATGCAC 1080 1081 CACAAACGCT CCAAACTCAA GCCTGATGAT GAGCCTCCCA GCCCTGGAGC AGTTAGTGTG 1140 1141 CAGGATCATC CGGATGGAAT GACCCTTGTG AAAGAGGAAG AAGATAAGGA AGATGGGAAA 1200 1201 CAAGAGCCAG AGGTGGTGTA TGAGACCAAC TGCCACTGGG AAAATTGCTG CAGAGAGTTT 1260 1261 GACACCCAGG AACAGCTTGT ACATCATATA AATAATGACC ATATCCATGG GGAGAAGAAG 1320 1321 GAGTTTGTAT GTCGATGGGA GGAGTGCTCT CGAGAACAGA AGCCCTTCAA GGCCCAGTAC 1380 1381 ATGCTGGTTG TACATATGCG CAGGCATACA GGCGAGAAAC CACACAAGTG CACGTTTGAG 1440 1441 GGCTGTTCCA AGGCCTATTC TAGATTGGAG AACTTGAAGA CACACTTGCG CTCTCACACA 1500 1501 GGAGAGAAAC CCTATGTGTG TGAACATGAG GGCTGCAACA AGGCCTTCTC GAATGCATCA 1560 1561 GACCGTGCCA AACATCAGAA TCGAACTCAC TCCAATGAGA AACCCTATGT ATGCAAGATA 1620 1621 CCAGGCTGCA CCAAACGCTA CACTGATCCG AGCTCTCTGC GCAAACATGT AAAAACCGTT 1680 1681 CATGGTCCTG AAGCCCATGT CACTAAGAAA CAGCGTGGAG ATGTTTTCCC CCGACCCCCG 1740 1741 GCCCATCCCC GTGAACCTGG AGCCAATGGA CAGGGCAGGT CGTCAAAATT GCAATGCCCC 1800 1801 TTTGAAGCAT TTCCAGACCA AAGGGAGTAT AACCATGCTA CCTCAAAGCA AGATGAATGT 1860 1861 CTGCAAGTCA AGTCAATCAA GACAGAGAAG CCGATGACGT CTCAGCCAAG CCCTGGCAGT 1920 1921 CAGTCTTCAT GCAGCAGTGG CCAGTCCCCC ACCAGCTCCC ATCTCAGCCG TGGAGTCCAG 1980 1981 CTTGCTGTGA ACACTATTGG CCTTGTCGGG GAGGAGGTGG TGGAGGACCA GGAGTTTGAA 2040 2041 GTGGAGGATG AAGAGAAGGA CACTGAGGTA GTAGAGGAGG AGTCTCCCAT AATGGTCTCT 2100 2101 ACTGTATCCA CTGCTACAGC CACGGCAGCT ACTGTAGCCC TACAGCCCTG CAGGAGTCTT 2160 2161 GGGCAGCCCT TGCGCTGGAT GGAACAGGTT AAGATGGAAA GGCTTAGGCA GGTGAATGGA 2220 2221 GGGACATCAA GGCTGGGACA TCTGTCACCC ACAGCACCCT CTAAAGGCCA CAGTCTGCCC 2280 2281 TCCCTGACAA TGAAAGGCTT GTGTACAGTC AGGAGTACTT GTGGGGGTGC ACCAGTGCCT 2340 2341 CAGCCTCCTT TGCATCCCGA GCCATCCAGC ACAGAGCTGA CAATGCTGAG CCTCCTACGG 2400 2401 GATCGCCGTG ACAGCAGTGG CAGTGCCACC AGCTCAGCCT ACCTAAGTAG CAGCCGTCGT 2460 2461 TCATCTGGCA TCTCTCCCTG CTTCTCAAGC CGCCGCTCCA GCCAAGCCTC ACGGTCTGAG 2520 2521 CACAGCCAGC AAAGACAGCT ACACAACCTC AGTGCTACTG ACTCCTATGA CCCCATTTCC 2580 2581 ACTGATGCCT CTCGTCGCTC CAGTGATGCT AGCCAATGTG GTGGAGGTGG TGGTTCTGGT 2640 2641 GGGGTAGTGC TTGGAAGAAG CTGGGGTAGT CGAAGTGGAG GTGTGGGAGG AGGTGGGATG 2700 2701 GGATCAAGAG GTGTGTTGAA CCTAACACCA GCACAGCATT ATCATCTCAA AGCCACATAT 2760 2761 GCAGCTGCAA CAGGTGGGCC CCCTCCAACA CCTTTGCCTA AACTGGAACA AGTGAGCTAT 2820 2821 AAAATTCAAA TGACTATGGC CAGGGATGTG AAAGGCACAA ACCAGCTCCC ATTGCCATCA 2880 2881 CTATTCAGAC CTCGTTGCAG TAGTGATGGT AGTTCTCATG GACAAAGCAG TCACATTAGG 2940 2941 TACAGATGGA GGAGATTGTA TCCAGGGGAA GGCCCAGGCA ATAGTAACAG AAGAGCAAGT 3000 3001 GACCCTCTAA TGCCAAGAGA CCAAAATAAC ACTGGAAATC CCCAGATACA GCGTTTTGGC 3060 3061 AGCCAAAATA ACATGGACCA ATTACCCCCT CTGGTTGGTA ATAATGTCTC AAGTGGTGTT 3120 3121 GGTAAAAGTA CAAACCACCA AAATGACACC AACTTAGTGG ACATTATCCA GAGTGGCCAG 3180 3181 CTCTCCCCTT TCCCTCCTAG CATCATGGAA CAATCAGCAC TTGAAGCTTT AGCCATTGAG 3240 3241 CATGATGGGG CGCTCTTATT TAAGGATGAT GGTTGTCTTC TTGGGGACCA TAAAGCTCCC 3300 3301 TGCAGCCAGC AAAATGGCAT AAATTCCCAA TTTCACAGAA ATGATTTTAC CCAGAATAGT 3360 3361 AAGGAGGTGC AGAAAGTCCA GAATCCTTCA CAGGACCATG GGGCACAAGA AGCACAAAAT 3420 3421 CCTAGGAAAG ATAGCCTGCC AATCCAATGG AATGAGGTAA GCTCAGGAAG TACGGATTTT 3480 3481 TCGTCTCCTT GGGAGCCATG GAGGTGTGAG CAGTGGCCAA ACCATATTAA TACAGTAGGC 3540 3541 CTTCCATTTG GTCACTTTGA AAATATGATT GTACAACAGC AGCTCCCTTC ATACTTTACA 3600 3601 GACCAGCGAC ATCCTAATCA GAGGGGTAGT GTTCAACAAA TAACTGAACT GACCGATGGA 3660 3661 CACATTTACC CAAATCAGCA CAGGCAAGGA TCAAATCCAA GCCAACATCG ATCTTGCAGA 3720 3721 ATGAGCCAGG GTGTGTCAGT GGAGACTACA CAACGGAACT GTAATGGCAC AAGCTCAAGC 3780 3781 ACATATAACT TTGGTCAGCA AAACTGTCAG AATGCGCTGG GCCTCATCCA ACCAAGTAGT 3840 3841 GTTCATCAAG CCACTCAGCC ACAAACTCAG CCACAAACAC AACAGCTTCA ACAGAGCCAT 3900 3901 GAAATTCCAT GTCAAACAAG TGGAAACTTA CTCCAGCAAG GAACAGTAAA GCCCAGTACA 3960 3961 TCCCACATCT CTGTACTCTC TCTTCAGCCA GCTAGCCAGC ATGTGGACCA AGACCCCTCT 4020 4021 CAACCACAAC AATATTCCAC CCAACAGATA ATCGGCAGTC ATAATGCACA GTCCTACAAA 4080 4081 AGTTTTACAA AAGGAAATAT CAGTAACCGC TCACTTGCTA ATCATGTTTC AGGACTAAAA 4140 4141 CTAGAAATAG AAGATCAGCT TCAACCAAAC TCATGCTCTT CAATGCAGCA ACAGCAGATC 4200 4201 TTTGAGCAGT GGTTTGACCC AGCTAAGTCT TCAATCTTCA GAGCTCAACA CTGCCAAATG 4260 4261 GAATCATTTA AAATTGAGAC TGGGATATCA TGTGAATCCT TGGAGGATGT TCTGTCACCT 4320 4321 GGGGCAGATC AGGTGACCAG CACAGTAGAG AGCAGCCCAG ATGGCAGTGT TCGGGATGTC 4380 4381 GGCATACATT TTTTCTCCAT CCTGGACGAT AGCCTTGACC AGGGCAGTTT GGTTTCTGAT 4440 4441 GTCATCAGTC CTAGTGTTGT GCATGATTTA TCACAGACTT CCTCTTGTCT TACAACTCCA 4500 4501 AACCTCTCAG CTGTACTTCA TAGCTTGCCT CTTGGTACAA CCAACATGGC CATTGGAGAC 4560 4561 ATGAGCTCAT TTCTGACTAC CCTTGCAGAA GAGAGCAAGT TTCTTGCCAT TATGCAGTAG 4620 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Tar-3544 | Takifugu rubripes | 77.99 | 0.0 | 935 |
| LLPS-Meg-3122 | Meleagris gallopavo | 77.88 | 0.0 | 704 |
| LLPS-Orn-3138 | Oreochromis niloticus | 74.83 | 0.0 | 1043 |
| LLPS-Gaa-0409 | Gasterosteus aculeatus | 74.5 | 0.0 | 1004 |
| LLPS-Dio-3637 | Dipodomys ordii | 69.01 | 0.0 | 796 |
| LLPS-Mam-4496 | Macaca mulatta | 68.14 | 0.0 | 807 |
| LLPS-Fec-2439 | Felis catus | 65.22 | 2e-60 | 229 |
| LLPS-Caf-2196 | Canis familiaris | 65.22 | 3e-60 | 229 |
| LLPS-Mup-4487 | Mustela putorius furo | 65.22 | 2e-61 | 229 |
| LLPS-Ran-4531 | Rattus norvegicus | 65.22 | 4e-61 | 229 |
| LLPS-Bot-1365 | Bos taurus | 65.22 | 2e-60 | 229 |
| LLPS-Otg-0476 | Otolemur garnettii | 64.6 | 5e-61 | 228 |
| LLPS-Lac-3853 | Latimeria chalumnae | 64.6 | 1e-58 | 222 |
| LLPS-Scf-1108 | Scleropages formosus | 64.42 | 1e-60 | 226 |
| LLPS-Ten-3250 | Tetraodon nigroviridis | 64.2 | 3e-60 | 224 |
| LLPS-Anp-2305 | Anas platyrhynchos | 63.98 | 8e-59 | 223 |
| LLPS-Gaga-2919 | Gallus gallus | 63.98 | 2e-58 | 223 |
| LLPS-Pof-0395 | Poecilia formosa | 63.8 | 5e-59 | 224 |
| LLPS-Dar-0462 | Danio rerio | 63.8 | 4e-59 | 224 |
| LLPS-Scm-1381 | Scophthalmus maximus | 63.8 | 3e-59 | 227 |
| LLPS-Xim-2148 | Xiphophorus maculatus | 63.8 | 1e-58 | 224 |
| LLPS-Rhb-0777 | Rhinopithecus bieti | 63.47 | 5e-61 | 231 |
| LLPS-Man-2574 | Macaca nemestrina | 63.47 | 1e-60 | 229 |
| LLPS-Loa-3810 | Loxodonta africana | 63.47 | 2e-60 | 229 |
| LLPS-Pat-4921 | Pan troglodytes | 63.47 | 2e-60 | 229 |
| LLPS-Hos-3295 | Homo sapiens | 63.47 | 1e-60 | 229 |
| LLPS-Ict-1967 | Ictidomys tridecemlineatus | 63.47 | 1e-60 | 229 |
| LLPS-Poa-0887 | Pongo abelii | 63.47 | 1e-60 | 229 |
| LLPS-Eqc-4290 | Equus caballus | 63.47 | 1e-60 | 229 |
| LLPS-Cap-4677 | Cavia porcellus | 63.47 | 8e-61 | 230 |
| LLPS-Caj-2987 | Callithrix jacchus | 63.47 | 1e-60 | 229 |
| LLPS-Gog-4613 | Gorilla gorilla | 63.47 | 8e-61 | 230 |
| LLPS-Aon-2599 | Aotus nancymaae | 63.47 | 8e-61 | 230 |
| LLPS-Sus-4799 | Sus scrofa | 63.47 | 2e-61 | 230 |
| LLPS-Maf-0893 | Macaca fascicularis | 63.47 | 1e-60 | 229 |
| LLPS-Mum-2884 | Mus musculus | 63.47 | 7e-61 | 230 |
| LLPS-Chs-2699 | Chlorocebus sabaeus | 63.47 | 5e-61 | 229 |
| LLPS-Paa-4285 | Papio anubis | 63.47 | 9e-61 | 230 |
| LLPS-Mal-2300 | Mandrillus leucophaeus | 63.47 | 1e-60 | 229 |
| LLPS-Myl-1251 | Myotis lucifugus | 63.47 | 5e-61 | 229 |
| LLPS-Tut-1367 | Tursiops truncatus | 63.47 | 2e-61 | 228 |
| LLPS-Pes-2607 | Pelodiscus sinensis | 63.35 | 2e-58 | 221 |
| LLPS-Mea-2448 | Mesocricetus auratus | 63.31 | 9e-61 | 230 |
| LLPS-Fia-3441 | Ficedula albicollis | 63.19 | 4e-59 | 224 |
| LLPS-Orl-0799 | Oryzias latipes | 63.19 | 2e-57 | 221 |
| LLPS-Fud-3258 | Fukomys damarensis | 62.94 | 2e-60 | 227 |
| LLPS-Orc-2956 | Oryctolagus cuniculus | 62.87 | 3e-60 | 228 |
| LLPS-Urm-2699 | Ursus maritimus | 62.77 | 2e-135 | 437 |
| LLPS-Tag-2038 | Taeniopygia guttata | 62.58 | 9e-59 | 222 |
| LLPS-Ova-3202 | Ovis aries | 62.11 | 3e-58 | 221 |
| LLPS-Cas-0752 | Carlito syrichta | 60.25 | 1e-54 | 209 |
| LLPS-Pap-1924 | Pan paniscus | 57.52 | 2e-49 | 191 |
| LLPS-Nol-1991 | Nomascus leucogenys | 57.52 | 2e-49 | 191 |
| LLPS-Cea-3092 | Cercocebus atys | 57.52 | 1e-49 | 191 |
| LLPS-Mod-0422 | Monodelphis domestica | 57.43 | 4e-47 | 183 |
| LLPS-Aim-2070 | Ailuropoda melanoleuca | 57.14 | 5e-48 | 187 |
| LLPS-Ora-0352 | Ornithorhynchus anatinus | 56.86 | 3e-50 | 192 |
| LLPS-Drm-2364 | Drosophila melanogaster | 55.92 | 7e-48 | 182 |
| LLPS-Leo-3007 | Lepisosteus oculatus | 54.32 | 0.0 | 1157 |
| LLPS-Anc-2509 | Anolis carolinensis | 54.31 | 5e-115 | 397 |
| LLPS-Asm-0713 | Astyanax mexicanus | 54.27 | 2e-49 | 190 |
| LLPS-Xet-2001 | Xenopus tropicalis | 53.12 | 9e-47 | 182 |