LLPS-Icp-3875
ARHGEF10
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Rho guanine nucleotide exchange factor 10 |
| Gene Name: | ARHGEF10, arhgef10 |
| Ensembl Gene: | ENSIPUG00000015981.1 |
| Ensembl Protein: | ENSIPUP00000024090.1 |
| Organism: | Ictalurus punctatus |
| Taxa ID: | 7998 |
| LLPS Type: | Client |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSIPUT00000025106.1 | ENSIPUP00000024090.1 |
| Ensembl | ENSIPUT00000025209.1 | ENSIPUP00000024189.1 |
| Ensembl | ENSIPUT00000025286.1 | ENSIPUP00000024262.1 |
| Ensembl | ENSIPUT00000025266.1 | ENSIPUP00000024244.1 |
| Ensembl | ENSIPUT00000025159.1 | ENSIPUP00000024141.1 |
| Ensembl | ENSIPUT00000025387.1 | ENSIPUP00000024361.1 |
| UniProt | W5UID9, W5UID9_ICTPU | |
| GeneBank | JT415680 | AHH41786.1 |
| RefSeq | , XM_017476729.1 | , XP_017332218.1, XP_017332218.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEQDDFPPPP PDVLDEEEGE SFEFDDEAPE AERPPSFPPA LDFDSSGCPV LENAEADLPP 60 61 PPPPQTCSSA PHGQFPPPPE EGHGADKELP PPPEGADTQG NPGSRRKVNP YSVIDISPDS 120 121 PPPLFSPANG NEADAQDVPS SPIVPSGYMV PVPCGYASPS NVPIITPAYT TPVIIRHFSV 180 181 DEEVSIVGAG PTLTDSVFTV DHPAIREEDA LAKWASDPAN TAWMENPDEV IYDDVPRENS 240 241 GSTTDVDEMI YDDVELGEEG GSSSVENGWS SSEFESYDEE SDGEGGHGEN GVLPNAFIRR 300 301 HTPSTKTHLS QDLTRLKEHY ERKVKDLMVN AVGAVELQQL RHKHEQKMQK LVRAAKHGTK 360 361 DGLEKTKAAV KKGKSFIRTK SFGHERKASC FEEEPSELFI EVECLNVEPV LGPAPEGLSQ 420 421 QQVVRRCILE SILESEKNYL DSLKRILEHY EKPLQELEPR LLSERKCKAV FYRVREILQC 480 481 HAMFQIALAS RVADWDQLQT IGDVFVASFS KSMVLDAYSE YVNNFNTAMA VVRKACTSKP 540 541 CFLDFLKQRQ ESSRDHVTLY GLMMKPIQRF PQFILLLQDM LKNTPVGHDD RLPLQMALTE 600 601 LETLSEKLNE RKRDADQRCE IRHIAKAMNE RYLNKLLSVG SRYLIRSDDV VETVYNERGE 660 661 IVKTKERRLF LLNDVLMCAT PNLRSPQDGG GAVVPSGQRF LLKWSVPLSL VEPVEFGSSE 720 721 EMGDSVPFPA LHSGEKVVVN AKPNKLYVGP GQLYQDLQNL IHDLGLVNQI STMISSLKGN 780 781 YQNVNGTVAQ DWISGLQRLI LKKEEEIRAA DRCRIQLQLP GKQDKSGRPT SFTAVFNTLS 840 841 PSIKQAWISN LQMAKLALEE HNVQGWFIAD DDGNQIKKQK HPLLLKHMPV VMSRLQEFKV 900 901 ECAVHNPEPH VNSESTADVP AVGHGCVWVA SCTNQMAQIA VVAMQNSSPK VTECFNVESR 960 961 ILCMTYVPVD EPPEDREGNP EPRCCNTPNV CVGTEEGSIS VYKSSQRSKK VRLQHFFTPD 1020 1021 KAAVTCLAYK SPFLYAGLVS GSLAVYSRTP DGSWDFSSVR LLKLGVLPVK ALLAVGECVW 1080 1081 ASSGGHVFVI DARTHTMEHQ LEAHQEEGMV VSQMVVAGVG IWIAFSSGST LRLFHTETLE 1140 1141 HLQDINISTP VHNILSGHQR VSVSSLLVCH GLLLVGTNLG VTVALSVPRL QGIPKVTGRG 1200 1201 MVSFHAHHSP VKFLIMASPV RNAVPTITDP PSQRAPPSEE DETPRCTASF LAEGDGVHPV 1260 1261 PIRQDSLSSS RSSLEHGPED GAIYDLLSDP AHSQNTKRVQ RANVSSVLVL SGGSGHRKIN 1320 1321 RKSKAARHEE NMPTVMVWQI PVPDV 1345 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTTCCGGG TCTTTCCTCA CTTCCACAAG GACGATGCAC CTCCTCAAAA GGCTGTGCTA 60 61 GATGAAGAAG AAGGTGAAAG TTTTGAATTT GATGATGAAG CCCCCGAGGC CGAGCGCCCT 120 121 CCCTCATTCC CTCCTGCTCT GGATTTCGAC TCTTCAGGCT GCCCGGTTTT GGAGAATGCC 180 181 GAGGCCGATC TCCCGCCACC ACCACCGCCG CAGACCTGTT CTTCTGCTCC ACACGGTCAG 240 241 TTCCCTCCAC CTCCTGAAGA GGGACATGGT GCAGATAAAG AGCTCCCGCC GCCTCCAGAG 300 301 GGCGCTGATA CACAAGGGAA TCCCGGGTCC CGACGCAAAG TCAACCCGTA CTCGGTGATC 360 361 GACATTTCCC CCGACAGCCC GCCTCCTTTG TTTTCCCCAG CCAATGGGAA TGAAGCTGAT 420 421 GCCCAGGACG TACCCAGCAG CCCCATTGTG CCCTCTGGAT ACATGGTGCC TGTGCCTTGC 480 481 GGCTATGCCT CGCCCTCCAA CGTCCCAATC ATCACCCCAG CCTACACCAC GCCTGTCATC 540 541 ATCAGACACT TCTCAGTGGA TGAAGAAGTG AGCATTGTGG GGGCGGGGCC TACTCTGACT 600 601 GACAGCGTCT TCACCGTAGA CCATCCGGCG ATAAGGGAGG AAGACGCTCT GGCGAAGTGG 660 661 GCTTCGGACC CTGCTAACAC GGCCTGGATG GAGAATCCAG ATGAAGTTAT TTACGACGAC 720 721 GTTCCGAGAG AGAATTCGGG ATCCACTACA GACGTGGATG AGATGATCTA TGATGATGTG 780 781 GAGCTGGGTG AAGAGGGAGG TAGCAGCTCC GTGGAGAACG GCTGGAGCTC CAGCGAGTTC 840 841 GAGAGCTACG ATGAGGAGAG CGATGGAGAA GGCGGGCACG GAGAGAACGG CGTCCTCCCC 900 901 AACGCCTTCA TCCGCCGACA CACACCCAGC ACCAAAACAC ACCTCTCTCA AGATCTGACA 960 961 CGCTTGAAAG AGCACTATGA GCGAAAGGTG AAAGATCTCA TGGTGAACGC AGTGGGCGCG 1020 1021 GTCGAGCTGC AGCAGCTCAG ACACAAACAT GAGCAGAAGA TGCAAAAGCT GGTGAGGGCG 1080 1081 GCCAAGCACG GCACCAAAGA CGGCCTGGAG AAAACCAAAG CGGCGGTCAA GAAGGGAAAG 1140 1141 TCCTTCATTC GAACCAAATC TTTTGGTCAC GAGAGGAAGG CATCATGTTT TGAGGAAGAG 1200 1201 CCATCCGAAC TCTTCATCGA GGTGGAATGT TTAAACGTGG AGCCTGTGTT AGGCCCCGCC 1260 1261 CCTGAGGGCC TCTCTCAACA GCAGGTGGTG AGGAGATGTA TTCTGGAGTC AATATTAGAG 1320 1321 AGTGAGAAGA ATTATTTAGA CTCGCTGAAG AGAATATTAG AGCACTACGA GAAGCCGCTG 1380 1381 CAGGAGCTCG AGCCTCGGCT GCTGAGCGAG AGGAAGTGTA AGGCGGTGTT TTACCGTGTG 1440 1441 AGGGAGATCC TGCAGTGCCA CGCCATGTTC CAGATCGCCC TGGCCAGCCG TGTGGCAGAC 1500 1501 TGGGACCAGC TCCAGACCAT CGGGGACGTC TTCGTCGCCT CCTTCTCTAA ATCCATGGTT 1560 1561 CTGGACGCGT ACAGCGAGTA CGTGAATAAC TTCAATACGG CCATGGCGGT GGTGAGGAAG 1620 1621 GCATGCACCT CCAAACCCTG CTTCCTCGAC TTCCTCAAGC AACGTCAGGA GAGCAGTCGC 1680 1681 GATCACGTCA CGCTCTACGG CCTCATGATG AAACCCATCC AGAGATTCCC ACAGTTCATT 1740 1741 CTGCTCCTGC AGGACATGCT GAAGAACACA CCGGTGGGCC ACGATGACCG CTTGCCCCTA 1800 1801 CAGATGGCCC TGACTGAGTT GGAGACTCTG TCTGAGAAGC TGAACGAGAG GAAGAGAGAC 1860 1861 GCAGATCAGC GCTGTGAGAT CCGACACATC GCCAAGGCCA TGAACGAGCG CTACCTCAAC 1920 1921 AAGCTCCTGA GTGTGGGTAG CAGGTATCTG ATCCGCTCGG ACGACGTGGT GGAGACCGTG 1980 1981 TACAACGAGC GAGGAGAGAT CGTCAAGACC AAAGAGAGAC GACTTTTCCT GCTTAATGAC 2040 2041 GTGCTCATGT GCGCCACGCC CAACCTGCGC TCTCCTCAGG ATGGTGGAGG TGCCGTCGTT 2100 2101 CCTTCAGGCC AGCGTTTCCT GCTCAAGTGG AGCGTCCCTC TCAGCCTGGT GGAGCCGGTG 2160 2161 GAGTTCGGCT CCTCGGAGGA GATGGGAGAC TCCGTCCCTT TCCCCGCCCT TCACTCCGGA 2220 2221 GAGAAGGTGG TCGTCAACGC CAAGCCAAAT AAGTTGTACG TGGGTCCGGG TCAGCTTTAT 2280 2281 CAGGACCTGC AGAACCTGAT CCACGACCTC GGCCTCGTCA ATCAAATCTC CACCATGATC 2340 2341 AGCAGCCTCA AGGGCAACTA CCAGAACGTA AATGGGACAG TAGCTCAGGA CTGGATCTCT 2400 2401 GGTCTTCAGC GTCTTATCCT TAAGAAAGAG GAGGAGATTA GAGCTGCTGA TCGCTGCCGC 2460 2461 ATACAACTGC AGTTACCTGG AAAACAAGAC AAGTACACAC ACACGCACAC ACACACACAC 2520 2521 ACACACGCGC ACAACTATAT TACCTTACTG CAGGAGTTTA AGGTGGAGTG TGCGGTCCAT 2580 2581 AACCCAGAGC CCCACGTTAA CAGCGAGAGC ACGGCGGACG TACCGGCAGT GGGACACGGC 2640 2641 TGTGTTTGGG TGGCCAGCTG CACCAATCAG ATGGCTCAGA TCGCCGTAGT GGCCATGCAG 2700 2701 AACTCCAGCC CGAAGGTGAC CGAATGTTTC AACGTGGAGT CGCGGATCCT CTGCATGACC 2760 2761 TATGTACCTG TGGATGAGCC CCCGGAGGAC AGAGAAGGAA ACCCCGAGCC TCGGTGCTGC 2820 2821 AACACACCCA ACGTGTGTGT GGGGACAGAG GAGGGAAGCA TCTCCGTCTA TAAGAGCAGT 2880 2881 CAGCGATCCA AGAAGGTCCG ACTGCAGCAC TTCTTCACTC CGGATAAAGC CGCCGTGACG 2940 2941 TGTTTAGCGT ACAAGAGTCC GTTTCTCTAT GCCGGCCTGG TCAGCGGCTC CCTCGCCGTC 3000 3001 TACTCACGAA CACCAGACGG TTCATGGGAT TTCTCCAGCG TGCGGTTACT GAAGCTCGGC 3060 3061 GTGCTGCCGG TGAAGGCCCT GCTGGCCGTC GGAGAGTGTG TGTGGGCCTC ATCTGGCGGA 3120 3121 CACGTCTTCG TCATCGATGC TCGCACGCAC ACTATGGAGC ACCAGTTGGA GGCGCATCAG 3180 3181 GAGGAGGGGA TGGTCGTGTC CCAAATGGTG GTAGCAGGAG TGGGCATCTG GATTGCCTTC 3240 3241 AGCTCAGGTT CCACACTCCG CCTGTTCCAC ACTGAGACAC TGGAGCACCT GCAGGACATC 3300 3301 AACATCTCTA CACCTGTCCA CAACATCCTC TCGGGTCATC AGAGGGTCTC TGTGAGCAGT 3360 3361 CTGCTAGTGT GTCACGGTTT GCTACTCGTG GGGACGAATC TTGGGGTGAC GGTAGCTCTG 3420 3421 AGTGTCCCCC GACTACAGGG CATCCCCAAG GTCACAGGAC GAGGCATGGT GTCCTTCCAC 3480 3481 GCTCATCACA GCCCTGTGAA GTTCCTCATC ATGGCGTCGC CCGTACGGAA CGCTGTTCCC 3540 3541 ACCATCACTG ACCCGCCTAG TCAGCGTGCT CCTCCTTCAG AAGAGGACGA AACTCCCAGA 3600 3601 TGTACTGCTT CCTTTCTCGC CGAGGGAGAC GGCGTCCACC CCGTCCCGAT ACGCCAGGAC 3660 3661 TCGCTCTCGT CCTCCCGCAG CTCCCTGGAG CACGGTCCAG AGGACGGCGC CATCTACGAC 3720 3721 CTCCTCAGTG ATCCGGCGCA CTCGCAGAAC ACTAAGCGGG TGCAGCGGGC AAACGTGAGC 3780 3781 TCAGTGCTGG TGCTGTCCGG CGGCTCGGGT CACCGAAAAA TCAACAGGAA GAGTAAAGCG 3840 3841 GCACGACACG AAGAAAACAT GCCCACGGTC ATGGTGTGGC AGATCCCCGT GCCTGACGTG 3900 3901 TGA 3903 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Asm-1955 | Astyanax mexicanus | 75.08 | 0.0 | 1790 |
| LLPS-Orn-3000 | Oreochromis niloticus | 73.23 | 0.0 | 1710 |
| LLPS-Dar-1860 | Danio rerio | 72.79 | 0.0 | 1638 |
| LLPS-Scf-3586 | Scleropages formosus | 71.93 | 0.0 | 1703 |
| LLPS-Xim-2179 | Xiphophorus maculatus | 71.79 | 0.0 | 1734 |
| LLPS-Maf-1212 | Macaca fascicularis | 71.47 | 4e-159 | 513 |
| LLPS-Tar-1001 | Takifugu rubripes | 70.96 | 0.0 | 1714 |
| LLPS-Orl-1251 | Oryzias latipes | 70.87 | 0.0 | 1718 |
| LLPS-Pof-1537 | Poecilia formosa | 70.8 | 0.0 | 1737 |
| LLPS-Ten-2636 | Tetraodon nigroviridis | 70.63 | 0.0 | 1488 |
| LLPS-Leo-1862 | Lepisosteus oculatus | 67.06 | 0.0 | 1659 |
| LLPS-Tag-3543 | Taeniopygia guttata | 66.81 | 0.0 | 1283 |
| LLPS-Lac-1215 | Latimeria chalumnae | 64.79 | 0.0 | 1532 |
| LLPS-Caf-4301 | Canis familiaris | 64.63 | 0.0 | 1358 |
| LLPS-Myl-3764 | Myotis lucifugus | 64.48 | 0.0 | 1019 |
| LLPS-Xet-2925 | Xenopus tropicalis | 63.11 | 0.0 | 1476 |
| LLPS-Meg-3102 | Meleagris gallopavo | 62.5 | 0.0 | 827 |
| LLPS-Caj-2860 | Callithrix jacchus | 62.31 | 0.0 | 1362 |
| LLPS-Sah-2998 | Sarcophilus harrisii | 62.04 | 0.0 | 1467 |
| LLPS-Urm-2492 | Ursus maritimus | 61.63 | 0.0 | 1408 |
| LLPS-Mod-0013 | Monodelphis domestica | 61.42 | 0.0 | 1475 |
| LLPS-Loa-4215 | Loxodonta africana | 61.31 | 0.0 | 1471 |
| LLPS-Pes-1207 | Pelodiscus sinensis | 61.3 | 0.0 | 1497 |
| LLPS-Fia-0728 | Ficedula albicollis | 61.21 | 0.0 | 1522 |
| LLPS-Eqc-1012 | Equus caballus | 61.13 | 0.0 | 1444 |
| LLPS-Anp-0037 | Anas platyrhynchos | 61.08 | 0.0 | 1533 |
| LLPS-Aon-1567 | Aotus nancymaae | 60.55 | 0.0 | 1457 |
| LLPS-Fud-0179 | Fukomys damarensis | 60.49 | 0.0 | 1419 |
| LLPS-Ora-3289 | Ornithorhynchus anatinus | 60.48 | 0.0 | 1469 |
| LLPS-Gaga-2164 | Gallus gallus | 60.35 | 0.0 | 1519 |
| LLPS-Paa-2997 | Papio anubis | 60.14 | 0.0 | 1466 |
| LLPS-Fec-3660 | Felis catus | 59.92 | 0.0 | 1417 |
| LLPS-Cas-3836 | Carlito syrichta | 59.89 | 0.0 | 1439 |
| LLPS-Bot-0797 | Bos taurus | 59.81 | 0.0 | 1392 |
| LLPS-Mup-1788 | Mustela putorius furo | 59.8 | 0.0 | 1407 |
| LLPS-Mea-0334 | Mesocricetus auratus | 59.8 | 0.0 | 1400 |
| LLPS-Cea-4580 | Cercocebus atys | 59.71 | 0.0 | 1467 |
| LLPS-Chs-3633 | Chlorocebus sabaeus | 59.67 | 0.0 | 1463 |
| LLPS-Pat-4386 | Pan troglodytes | 59.64 | 0.0 | 1461 |
| LLPS-Aim-1733 | Ailuropoda melanoleuca | 59.52 | 0.0 | 1417 |
| LLPS-Mam-4306 | Macaca mulatta | 59.51 | 0.0 | 1459 |
| LLPS-Man-3625 | Macaca nemestrina | 59.51 | 0.0 | 1458 |
| LLPS-Hos-0321 | Homo sapiens | 59.48 | 0.0 | 1458 |
| LLPS-Pap-0022 | Pan paniscus | 59.44 | 0.0 | 1457 |
| LLPS-Gog-3508 | Gorilla gorilla | 59.37 | 0.0 | 1462 |
| LLPS-Sus-1996 | Sus scrofa | 59.37 | 0.0 | 1420 |
| LLPS-Poa-3191 | Pongo abelii | 59.3 | 0.0 | 1459 |
| LLPS-Ran-1116 | Rattus norvegicus | 59.2 | 0.0 | 1276 |
| LLPS-Mum-3771 | Mus musculus | 59.14 | 0.0 | 1392 |
| LLPS-Anc-1125 | Anolis carolinensis | 58.95 | 0.0 | 1429 |
| LLPS-Rhb-4592 | Rhinopithecus bieti | 58.81 | 0.0 | 1419 |
| LLPS-Otg-2240 | Otolemur garnettii | 58.06 | 0.0 | 1444 |
| LLPS-Ova-3830 | Ovis aries | 57.94 | 0.0 | 1339 |
| LLPS-Ict-0905 | Ictidomys tridecemlineatus | 57.87 | 0.0 | 1080 |
| LLPS-Mal-3841 | Mandrillus leucophaeus | 57.42 | 0.0 | 1351 |
| LLPS-Dio-2280 | Dipodomys ordii | 57.42 | 0.0 | 1343 |
| LLPS-Cap-0408 | Cavia porcellus | 56.24 | 0.0 | 1040 |
| LLPS-Nol-4435 | Nomascus leucogenys | 56.18 | 0.0 | 1337 |
| LLPS-Cii-2388 | Ciona intestinalis | 31.88 | 9e-86 | 298 |
| LLPS-Drm-1065 | Drosophila melanogaster | 31.28 | 1e-112 | 398 |
| LLPS-Ere-0363 | Erinaceus europaeus | 25.19 | 2e-12 | 75.9 |
| LLPS-Tut-0107 | Tursiops truncatus | 24.24 | 1e-13 | 80.9 |