LLPS-Hos-a323
LDHB

▼ OVERVIEW

Status: Reviewed
Protein Name: L-lactate dehydrogenase B chain
Gene Name: LDHB
Ensembl Gene: ENSG00000111716.12
Ensembl Protein: ENSP00000442680.1
Organism: Homo sapiens
Taxa ID: 9606
LLPS Type: Others
PDB: 1T2F (A) More


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Postsynaptic density
"...We report the first direct comparison of the proteome of triplicate isolates of mouse and human cortical postsynaptic densities. The mouse postsynaptic density comprised 1556 proteins and the human one 1461."
Human cortex23071613

▼ SEQUENCE

Protein Sequence (FASTA)
1     MATLKEKLIA  PVAEEEATVP  NNKITVVGVG  QVGMACAISI  LGKSLADELA  LVDVLEDKLK  60
61    GEMMDLQHGS  LFLQTPKIVA  DKDYSVTANS  KIVVVTAGVR  QQEGESRLNL  VQRNVNVFKF  120
121   IIPQIVKYSP  DCIIIVVSNP  VDILTYVTWK  LSGLPKHRVI  GSGCNLDSAR  FRYLMAEKLG  180
181   IHPSSCHGWI  LGEHGDSSVA  VWSGVNVAGV  SLQELNPEMG  TDNDSENWKE  VHKMVVESAY  240
241   EVIKLKGYTN  WAIGLSVADL  IESMLKNLSR  IHPVSTMVKG  MYGIENEVFL  SLPCILNARG  300
301   LTSVINQKLK  DDEVAQLKKS  ADTLWDIQKD  LKDL  334
Nucleotide CDS Sequence (FASTA)
1     ATGGCAACTC  TTAAGGAAAA  ACTCATTGCA  CCAGTTGCGG  AAGAAGAGGC  AACAGTTCCA  60
61    AACAATAAGA  TCACTGTAGT  GGGTGTTGGA  CAAGTTGGTA  TGGCGTGTGC  TATCAGCATT  120
121   CTGGGAAAGT  CTCTGGCTGA  TGAACTTGCT  CTTGTGGATG  TTTTGGAAGA  TAAGCTTAAA  180
181   GGAGAAATGA  TGGATCTGCA  GCATGGGAGC  TTATTTCTTC  AGACACCTAA  AATTGTGGCA  240
241   GATAAAGATT  ATTCTGTGAC  TGCCAATTCT  AAGATTGTAG  TGGTAACTGC  AGGAGTCCGT  300
301   CAGCAAGAAG  GGGAGAGTCG  GCTCAATCTG  GTGCAGAGAA  ATGTTAATGT  CTTCAAATTC  360
361   ATTATTCCTC  AGATCGTCAA  GTACAGTCCT  GATTGCATCA  TAATTGTGGT  TTCCAACCCA  420
421   GTGGACATTC  TTACGTATGT  TACCTGGAAA  CTAAGTGGAT  TACCCAAACA  CCGCGTGATT  480
481   GGAAGTGGAT  GTAATCTGGA  TTCTGCTAGA  TTTCGCTACC  TTATGGCTGA  AAAACTTGGC  540
541   ATTCATCCCA  GCAGCTGCCA  TGGATGGATT  TTGGGGGAAC  ATGGCGACTC  AAGTGTGGCT  600
601   GTGTGGAGTG  GTGTGAATGT  GGCAGGTGTT  TCTCTCCAGG  AATTGAATCC  AGAAATGGGA  660
661   ACTGACAATG  ATAGTGAAAA  TTGGAAGGAA  GTGCATAAGA  TGGTGGTTGA  AAGTGCCTAT  720
721   GAAGTCATCA  AGCTAAAAGG  ATATACCAAC  TGGGCTATTG  GATTAAGTGT  GGCTGATCTT  780
781   ATTGAATCCA  TGTTGAAAAA  TCTATCCAGG  ATTCATCCCG  TGTCAACAAT  GGTAAAGGGG  840
841   ATGTATGGCA  TTGAGAATGA  AGTCTTCCTG  AGCCTTCCAT  GTATCCTCAA  TGCCCGGGGA  900
901   TTAACCAGCG  TTATCAACCA  GAAGCTAAAG  GATGATGAGG  TTGCTCAGCT  CAAGAAAAGT  960
961   GCAGATACCC  TGTGGGACAT  CCAGAAGGAC  CTAAAAGACC  TGTGA  1005

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pat-a315Pan troglodytes100.00.0681
LLPS-Cea-a319Cercocebus atys100.00.0681
LLPS-Mam-a315Macaca mulatta100.00.0681
LLPS-Gog-a314Gorilla gorilla100.00.0596
LLPS-Poa-a315Pongo abelii100.00.0681
LLPS-Maf-a319Macaca fascicularis100.00.0681
LLPS-Pap-a314Pan paniscus100.00.0681
LLPS-Man-a318Macaca nemestrina100.00.0681
LLPS-Paa-a318Papio anubis100.00.0681
LLPS-Nol-a313Nomascus leucogenys100.00.0681
LLPS-Caj-a316Callithrix jacchus99.70.0679
LLPS-Chs-a315Chlorocebus sabaeus99.70.0679
LLPS-Orc-a306Oryctolagus cuniculus99.660.0593
LLPS-Urm-a292Ursus maritimus99.40.0678
LLPS-Eqc-a324Equus caballus99.40.0669
LLPS-Fec-a319Felis catus99.10.0674
LLPS-Mup-a317Mustela putorius furo99.10.0676
LLPS-Aim-a308Ailuropoda melanoleuca98.80.0676
LLPS-Cas-a290Carlito syrichta98.80.0674
LLPS-Mal-a309Mandrillus leucophaeus98.20.0673
LLPS-Otg-a321Otolemur garnettii98.20.0672
LLPS-Loa-a312Loxodonta africana98.20.0668
LLPS-Bot-a323Bos taurus98.20.0670
LLPS-Mea-a294Mesocricetus auratus98.20.0671
LLPS-Caf-a318Canis familiaris97.90.0666
LLPS-Fud-a312Fukomys damarensis97.90.0667
LLPS-Mum-a323Mus musculus97.90.0669
LLPS-Ran-a320Rattus norvegicus97.90.0670
LLPS-Myl-a302Myotis lucifugus97.630.0667
LLPS-Mod-a303Monodelphis domestica97.60.0668
LLPS-Sus-a321Sus scrofa97.60.0670
LLPS-Cap-a317Cavia porcellus97.60.0663
LLPS-Sah-a298Sarcophilus harrisii97.350.0602
LLPS-Dio-a311Dipodomys ordii96.710.0658
LLPS-Ova-a313Ovis aries96.440.0658
LLPS-Aon-a323Aotus nancymaae96.410.0657
LLPS-Ict-a318Ictidomys tridecemlineatus95.810.0647
LLPS-Rhb-a311Rhinopithecus bieti95.060.0657
LLPS-Pes-a282Pelodiscus sinensis91.020.0624
LLPS-Gaga-a283Gallus gallus90.120.0617
LLPS-Anp-a267Anas platyrhynchos89.580.0572
LLPS-Fia-a274Ficedula albicollis86.830.0602
LLPS-Tag-a275Taeniopygia guttata84.980.0589
LLPS-Xet-a281Xenopus tropicalis84.430.0592
LLPS-Anc-a296Anolis carolinensis84.130.0589
LLPS-Leo-a283Lepisosteus oculatus81.790.0543
LLPS-Lac-a286Latimeria chalumnae81.60.0572
LLPS-Asm-a275Astyanax mexicanus81.140.0541
LLPS-Orl-a277Oryzias latipes80.540.0540
LLPS-Dar-a282Danio rerio79.940.0565
LLPS-Orn-a281Oreochromis niloticus79.940.0540
LLPS-Scm-a266Scophthalmus maximus79.940.0543
LLPS-Pof-a283Poecilia formosa79.340.0539
LLPS-Xim-a287Xiphophorus maculatus79.340.0537
LLPS-Ora-a275Ornithorhynchus anatinus78.791e-165473
LLPS-Icp-a284Ictalurus punctatus78.740.0538
LLPS-Ten-a272Tetraodon nigroviridis77.840.0533
LLPS-Gaa-a273Gasterosteus aculeatus77.250.0522
LLPS-Scf-a265Scleropages formosus76.650.0514
LLPS-Tar-a271Takifugu rubripes76.350.0514
LLPS-Ere-1069Erinaceus europaeus70.789e-171487
LLPS-Cae-a059Caenorhabditis elegans63.882e-137402
LLPS-Drm-a086Drosophila melanogaster61.983e-152440
LLPS-Cii-a096Ciona intestinalis59.094e-124369
LLPS-Php-a055Physcomitrella patens58.052e-119360
LLPS-Cis-a081Ciona savignyi57.881e-135398
LLPS-Sot-a043Solanum tuberosum54.919e-121360
LLPS-Sem-2359Selaginella moellendorffii54.362e-112338
LLPS-Hea-1512Helianthus annuus54.291e-114345
LLPS-Sob-2221Sorghum bicolor53.72e-114345
LLPS-Mae-a050Manihot esculenta52.961e-116350
LLPS-Phv-1376Phaseolus vulgaris51.967e-117350
LLPS-Tra-a062Triticum aestivum50.471e-109332
LLPS-Orbr-1618Oryza brachyantha50.468e-114343