LLPS-Hos-3470
RARS2

▼ OVERVIEW

Status: Unreviewed
Protein Name: Probable arginine--tRNA ligase, mitochondrial; Arginyl-tRNA synthetase; ArgRS
Gene Name: RARS2, RARSL
Ensembl Gene: ENSG00000146282.17
Ensembl Protein: ENSP00000389656.1
Organism: Homo sapiens
Taxa ID: 9606
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MACGFRRAIA  CQLSRVLNLP  PENLITSISA  VPISQKEEVA  DFQLSVDSLL  EKDNDHSRPD  60
61    IQVQAKRLAE  KLRCDTVVSE  ISTGQRTVNF  KINRELLTKT  VLQQVIEDGS  KYGLKSELFS  120
121   GLPQKKIVVE  FSSPNVAKKF  HVGHLRSTII  GNFIANLKEA  LGHQVIRINY  LGDWGMQFGL  180
181   LGTGFQLFGY  EEKLQSNPLQ  HLFEVYVQVN  KEAADDKSVA  KAAQEFFQRL  ELGDVQALSL  240
241   WQKFRDLSIE  EYIRVYKRLG  VYFDEYSGES  FYREKSQEVL  KLLESKGLLL  KTIKGTAVVD  300
301   LSGNGDPSSI  CTVMRSDGTS  LYATRDLAAA  IDRMDKYNFD  TMIYVTDKGQ  KKHFQQVFQM  360
361   LKIMGYDWAE  RCQHVPFGVV  QGMKTRRGDV  TFLEDVLNEI  QLRMLQNMAS  IKTTKELKNP  420
421   QETAERVGLA  ALIIQDFKGL  LLSDYKFSWD  RVFQSRGDTG  VFLQYTHARL  HSLEETFGCG  480
481   YLNDFNTACL  QEPQSVSILQ  HLLRFDEVLY  KSSQDFQPRH  IVSYLLTLSH  LAAVAHKTLQ  540
541   IKDSPPEVAG  ARLHLFKAVR  SVLANGMKLL  GITPVCRM  578
Nucleotide CDS Sequence (FASTA)
1     ATGGCGTGCG  GCTTTCGCCG  CGCTATTGCT  TGCCAGCTTT  CCAGAGTGTT  GAATCTTCCA  60
61    CCAGAAAACT  TGATCACATC  AATATCTGCA  GTTCCAATTT  CCCAAAAAGA  AGAAGTAGCT  120
121   GATTTTCAGC  TTTCTGTGGA  TTCTTTATTG  GAAAAAGACA  ATGACCATTC  AAGACCAGAT  180
181   ATTCAAGTTC  AAGCCAAGAG  ACTAGCAGAG  AAGCTAAGAT  GTGATACAGT  GGTGAGTGAA  240
241   ATCAGTACTG  GTCAAAGGAC  TGTAAATTTC  AAAATAAACA  GAGAGCTCTT  AACAAAGACA  300
301   GTGCTACAAC  AAGTAATTGA  AGATGGCTCA  AAATATGGAT  TAAAAAGTGA  ACTTTTCTCT  360
361   GGACTTCCCC  AGAAGAAGAT  TGTGGTTGAA  TTCAGTTCAC  CTAATGTTGC  CAAAAAATTT  420
421   CATGTTGGAC  ATTTGCGTTC  TACCATCATA  GGAAATTTTA  TAGCAAATCT  CAAAGAAGCT  480
481   TTAGGACATC  AAGTAATAAG  AATAAATTAC  CTTGGCGATT  GGGGCATGCA  GTTTGGTCTT  540
541   CTGGGAACTG  GCTTCCAGCT  GTTTGGCTAT  GAGGAAAAAC  TGCAGTCCAA  TCCTCTACAG  600
601   CATCTCTTTG  AAGTTTATGT  ACAAGTTAAT  AAAGAAGCAG  CAGATGATAA  AAGTGTAGCA  660
661   AAAGCAGCAC  AGGAGTTCTT  CCAACGATTG  GAACTGGGCG  ATGTGCAAGC  ACTTTCACTG  720
721   TGGCAAAAAT  TTCGGGACTT  GAGCATTGAA  GAGTACATTC  GGGTTTACAA  GCGTCTGGGA  780
781   GTATATTTTG  ATGAATATTC  AGGAGAATCA  TTTTATCGTG  AAAAATCTCA  AGAGGTCTTA  840
841   AAGTTGCTGG  AGAGTAAAGG  ACTCCTACTG  AAAACAATAA  AAGGAACGGC  TGTAGTAGAT  900
901   CTCTCTGGGA  ATGGCGACCC  CTCCTCAATT  TGTACTGTAA  TGCGAAGTGA  TGGGACTTCT  960
961   CTCTATGCAA  CCAGAGATCT  TGCAGCTGCT  ATAGATCGAA  TGGACAAGTA  TAATTTTGAT  1020
1021  ACAATGATAT  ATGTGACAGA  TAAAGGACAA  AAAAAGCATT  TTCAGCAAGT  ATTCCAAATG  1080
1081  CTGAAGATCA  TGGGATATGA  CTGGGCAGAA  AGGTGCCAGC  ACGTGCCCTT  TGGAGTAGTA  1140
1141  CAGGGAATGA  AGACTCGAAG  AGGAGATGTC  ACTTTCCTGG  AAGATGTTTT  AAATGAGATT  1200
1201  CAATTAAGGA  TGCTACAGAA  CATGGCTTCA  ATTAAGACAA  CTAAAGAACT  CAAGAACCCA  1260
1261  CAAGAGACTG  CAGAGAGGGT  CGGGCTCGCA  GCACTCATTA  TTCAGGACTT  CAAAGGTTTA  1320
1321  CTCTTATCTG  ACTACAAGTT  CAGCTGGGAT  CGTGTTTTCC  AGAGTCGCGG  GGACACAGGA  1380
1381  GTCTTCCTAC  AGTACACACA  CGCCCGCCTC  CACAGTTTGG  AAGAGACTTT  TGGATGTGGG  1440
1441  TACCTGAATG  ACTTCAACAC  TGCTTGTTTA  CAAGAGCCAC  AGTCTGTTTC  AATTCTTCAG  1500
1501  CATCTTCTCA  GGTTCGACGA  GGTGCTTTAT  AAATCATCTC  AGGACTTTCA  ACCCAGGCAT  1560
1561  ATCGTCAGTT  ACCTTCTAAC  TTTAAGTCAT  CTTGCAGCTG  TGGCACACAA  AACACTACAA  1620
1621  ATAAAAGATA  GTCCTCCTGA  AGTGGCTGGG  GCCAGACTTC  ATCTTTTCAA  AGCTGTCCGT  1680
1681  TCTGTCCTAG  CCAATGGAAT  GAAACTTCTT  GGAATAACAC  CTGTATGTAG  GATGTAA  1737

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Poa-0358Pongo abelii99.130.01117
LLPS-Chs-0392Chlorocebus sabaeus98.790.01122
LLPS-Cea-1585Cercocebus atys98.620.01119
LLPS-Pap-3464Pan paniscus98.60.01098
LLPS-Gog-1979Gorilla gorilla98.60.01097
LLPS-Rhb-3682Rhinopithecus bieti98.440.01121
LLPS-Pat-3971Pan troglodytes98.430.01097
LLPS-Maf-0013Macaca fascicularis98.430.01110
LLPS-Paa-0019Papio anubis98.10.01114
LLPS-Mam-1798Macaca mulatta97.040.01084
LLPS-Caj-2869Callithrix jacchus96.540.01099
LLPS-Nol-2835Nomascus leucogenys96.530.01074
LLPS-Aon-2094Aotus nancymaae95.830.01074
LLPS-Man-3010Macaca nemestrina93.940.01047
LLPS-Cas-0495Carlito syrichta93.940.01066
LLPS-Eqc-2085Equus caballus93.910.01065
LLPS-Caf-4266Canis familiaris92.910.01071
LLPS-Sus-2143Sus scrofa92.890.01063
LLPS-Orc-2560Oryctolagus cuniculus92.680.01051
LLPS-Ict-2525Ictidomys tridecemlineatus92.560.01057
LLPS-Ova-4202Ovis aries92.560.01065
LLPS-Fec-4181Felis catus92.350.01055
LLPS-Myl-3723Myotis lucifugus92.060.01052
LLPS-Mal-2121Mandrillus leucophaeus92.040.01052
LLPS-Bot-3199Bos taurus91.480.01050
LLPS-Aim-2061Ailuropoda melanoleuca91.220.01043
LLPS-Loa-3700Loxodonta africana91.210.01036
LLPS-Dio-3715Dipodomys ordii90.480.01041
LLPS-Cap-3122Cavia porcellus90.140.01038
LLPS-Fud-1748Fukomys damarensis90.140.01046
LLPS-Otg-2172Otolemur garnettii89.620.01015
LLPS-Urm-1874Ursus maritimus88.870.01054
LLPS-Mum-4953Mus musculus86.510.0 995
LLPS-Ran-3536Rattus norvegicus85.640.0 980
LLPS-Mea-2809Mesocricetus auratus85.290.0 976
LLPS-Mod-3932Monodelphis domestica84.60.0 968
LLPS-Sah-2052Sarcophilus harrisii84.340.0 792
LLPS-Ora-0561Ornithorhynchus anatinus81.770.0 920
LLPS-Pes-3029Pelodiscus sinensis76.290.0 598
LLPS-Fia-1080Ficedula albicollis74.310.0 829
LLPS-Anp-3150Anas platyrhynchos73.80.0 556
LLPS-Gaga-2859Gallus gallus73.70.0 827
LLPS-Tag-0762Taeniopygia guttata72.510.0 825
LLPS-Meg-1550Meleagris gallopavo70.790.0 775
LLPS-Anc-1162Anolis carolinensis69.880.0 777
LLPS-Xet-0996Xenopus tropicalis60.510.0 662
LLPS-Scm-1787Scophthalmus maximus58.970.0 653
LLPS-Scf-2944Scleropages formosus58.820.0 656
LLPS-Ten-3399Tetraodon nigroviridis58.720.0 658
LLPS-Xim-1888Xiphophorus maculatus58.720.0 656
LLPS-Asm-2765Astyanax mexicanus58.650.0 655
LLPS-Pof-3457Poecilia formosa58.520.0 649
LLPS-Orl-0686Oryzias latipes58.20.0 664
LLPS-Tar-3050Takifugu rubripes57.170.0 647
LLPS-Gaa-3367Gasterosteus aculeatus57.020.0 620
LLPS-Orn-3644Oreochromis niloticus56.020.0 631
LLPS-Dar-4189Danio rerio55.090.0 620
LLPS-Leo-2048Lepisosteus oculatus51.642e-177 521
LLPS-Cis-1240Ciona savignyi41.631e-108 341
LLPS-Asg-1513Ashbya gossypii41.331e-122 383
LLPS-Kop-1443Komagataella pastoris41.224e-117 369
LLPS-Sac-0154Saccharomyces cerevisiae40.476e-126 390
LLPS-Miv-1586Microbotryum violaceum39.793e-94 320
LLPS-Yal-1523Yarrowia lipolytica39.662e-126 393
LLPS-Abg-0923Absidia glauca39.32e-120 379
LLPS-Tum-1469Tuber melanosporum39.144e-116 365
LLPS-Pug-0542Puccinia graminis38.963e-121 379
LLPS-Fuv-1054Fusarium verticillioides38.671e-108 346
LLPS-Fuo-1193Fusarium oxysporum38.483e-110 350
LLPS-Cogr-1660Colletotrichum graminicola38.065e-110 350
LLPS-Ved-1062Verticillium dahliae37.766e-100 323
LLPS-Asfu-1599Aspergillus fumigatus37.642e-120 377
LLPS-Scp-0784Schizosaccharomyces pombe37.647e-112 354
LLPS-Cog-0927Colletotrichum gloeosporioides37.482e-107 343
LLPS-Nef-0135Neosartorya fischeri37.483e-119 374
LLPS-Blg-0415Blumeria graminis37.361e-102 332
LLPS-Coo-0158Colletotrichum orbiculare37.332e-104 335
LLPS-Mel-1501Melampsora laricipopulina37.318e-116 364
LLPS-Put-1210Puccinia triticina37.245e-104 335
LLPS-Dos-0695Dothistroma septosporum37.199e-1994.4
LLPS-Scj-1112Schizosaccharomyces japonicus37.166e-100 323
LLPS-Nec-1437Neurospora crassa37.04e-113 360
LLPS-Crn-1097Cryptococcus neoformans36.883e-103 332
LLPS-Mao-1586Magnaporthe oryzae36.84e-106 342
LLPS-Beb-1317Beauveria bassiana36.764e-106 341
LLPS-Phn-0642Phaeosphaeria nodorum36.477e-111 355
LLPS-Asc-1303Aspergillus clavatus36.472e-113 362
LLPS-Scc-1561Schizosaccharomyces cryophilus36.442e-104 335
LLPS-Lem-1516Leptosphaeria maculans36.421e-113 365
LLPS-Pyt-0478Pyrenophora teres36.354e-115 363
LLPS-Ast-1352Aspergillus terreus36.323e-112 356
LLPS-Asn-1198Aspergillus nidulans36.232e-111 354
LLPS-Trr-0716Trichoderma reesei36.177e-109 348
LLPS-Map-0263Magnaporthe poae36.151e-103 335
LLPS-Gag-1453Gaeumannomyces graminis35.979e-105 336
LLPS-Asni-0594Aspergillus niger35.861e-114 362
LLPS-Pytr-0131Pyrenophora triticirepentis35.859e-114 360
LLPS-Usm-1523Ustilago maydis35.572e-97 317
LLPS-Fus-1360Fusarium solani35.466e-105 336
LLPS-Asf-0453Aspergillus flavus35.383e-110 352
LLPS-Spr-1357Sporisorium reilianum35.353e-95 311
LLPS-Aso-1500Aspergillus oryzae35.286e-110 350
LLPS-Trv-0039Trichoderma virens35.231e-101 328
LLPS-Arl-1456Arabidopsis lyrata35.023e-56 205
LLPS-Zyt-0264Zymoseptoria tritici34.453e-94 309
LLPS-Sei-0310Setaria italica34.15e-55 202
LLPS-Icp-1344Ictalurus punctatus34.094e-53 197
LLPS-Brr-1447Brassica rapa34.048e-55 201
LLPS-Zem-1931Zea mays33.932e-54 201
LLPS-Viv-1600Vitis vinifera33.894e-56 205
LLPS-Lep-0865Leersia perrieri33.66e-54 199
LLPS-Sob-0349Sorghum bicolor33.532e-56 206
LLPS-Chc-0709Chondrus crispus33.41e-50 189
LLPS-Art-2751Arabidopsis thaliana33.22e-56 206
LLPS-Ori-1866Oryza indica33.191e-52 195
LLPS-Tut-1272Tursiops truncatus33.131e-48 184
LLPS-Tra-2489Triticum aestivum33.085e-57 208
LLPS-Bro-2673Brassica oleracea33.072e-57 209
LLPS-Brn-2429Brassica napus33.071e-55 204
LLPS-Hov-0496Hordeum vulgare32.952e-56 207
LLPS-Prp-0585Prunus persica32.821e-54 201
LLPS-Via-0202Vigna angularis32.669e-48 181
LLPS-Sem-0941Selaginella moellendorffii32.632e-49 185
LLPS-Phv-0628Phaseolus vulgaris32.592e-47 180
LLPS-Cus-1488Cucumis sativus32.59e-54 198
LLPS-Ors-1312Oryza sativa32.499e-53 195
LLPS-Org-0529Oryza glaberrima32.491e-52 195
LLPS-Orm-0798Oryza meridionalis32.492e-52 195
LLPS-Orr-1759Oryza rufipogon32.492e-52 195
LLPS-Orni-0303Oryza nivara32.492e-52 195
LLPS-Orb-0378Oryza barthii32.492e-52 195
LLPS-Orp-1469Oryza punctata32.487e-53 196
LLPS-Vir-1307Vigna radiata32.462e-45 174
LLPS-Brd-0988Brachypodium distachyon32.455e-58 210
LLPS-Nia-1945Nicotiana attenuata32.45e-57 208
LLPS-Orgl-0625Oryza glumaepatula32.293e-51 192
LLPS-Orbr-1418Oryza brachyantha32.262e-53 198
LLPS-Mup-3086Mustela putorius furo32.241e-45 175
LLPS-Cym-0991Cyanidioschyzon merolae32.21e-0652.4
LLPS-Mae-0340Manihot esculenta31.972e-53 198
LLPS-Thc-1321Theobroma cacao31.977e-55 202
LLPS-Drm-2240Drosophila melanogaster31.941e-50 190
LLPS-Sol-0044Solanum lycopersicum31.847e-58 209
LLPS-Pot-1241Populus trichocarpa31.714e-53 197
LLPS-Gor-2574Gossypium raimondii31.524e-52 193
LLPS-Gas-0608Galdieria sulphuraria31.512e-52 195
LLPS-Hea-0734Helianthus annuus31.472e-55 203
LLPS-Glm-2056Glycine max31.382e-51 191
LLPS-Amt-1745Amborella trichopoda31.373e-45 174
LLPS-Coc-0286Corchorus capsularis31.027e-57 207
LLPS-Sot-1019Solanum tuberosum31.01e-29 123
LLPS-Php-2382Physcomitrella patens30.941e-53 199
LLPS-Met-0463Medicago truncatula30.751e-49 187
LLPS-Dac-1607Daucus carota30.582e-49 185
LLPS-Chr-0968Chlamydomonas reinhardtii30.436e-56 204
LLPS-Tru-0187Triticum urartu30.368e-42 166
LLPS-Mua-0358Musa acuminata30.257e-54 198
LLPS-Osl-0998Ostreococcus lucimarinus30.27e-44 169
LLPS-Lac-2104Latimeria chalumnae30.176e-49 185
LLPS-Cae-0929Caenorhabditis elegans30.135e-44 171
LLPS-Cii-0235Ciona intestinalis29.931e-56 207