LLPS-Hos-2739
RNF151

▼ OVERVIEW

Status: Reviewed
Protein Name: RING finger protein 151
Gene Name: RNF151
Ensembl Gene: ENSG00000179580.9
Ensembl Protein: ENSP00000456566.1
Organism: Homo sapiens
Taxa ID: 9606
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nuclear speckle
"...In total, we identified 325 proteins localized to distinct nuclear bodies, including nucleoli, promyelocytic leukemia nuclear bodies, nuclear speckles, paraspeckles, Cajal bodies, Sam68 nuclear bodies, Polycomb bodies, and uncharacterized nuclear bodies."
HeLa cells24127217

▼ FUNCTION

May be involved in acrosome formation of spermatids.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGGGYDLNLF  ASPPDSNFVC  SVCHGVLKRP  ARLPCSHIFC  KKCILRWLAR  QKTCPCCRKE  60
61    VKRKKVVHMN  KLRKTIGRLE  VKCKNADAGC  IVTCPLAHRK  GHQDSCPFEL  TACPNEGCTS  120
121   QVPRGTLAEH  RQHCQQGSQQ  RCPLGCGATL  DPAERARHNC  YRELHNAWSV  RQERRRPLLL  180
181   SLLRRVRWLD  QATSVVRREL  AELSNFLEED  TALLEGAPQE  EAEAAPEGNV  GAEVVGEPRA  240
241   NIPCK  245
Nucleotide CDS Sequence (FASTA)
1     GGTGGCGGGT  ATGATCTCAA  CCTCTTCGCC  AGCCCTCCTG  ACAGCAACTT  CGTGTGCTCC  60
61    GTCTGCCATG  GGGTTCTCAA  GAGGCCAGCA  AGGTTGCCAT  GCAGCCACAT  CTTCTGCAAA  120
121   AAGTGCATCC  TCCGGTGGCT  AGCCAGACAA  AAGACCTGTC  CGTGCTGTAG  GAAAGAGGTG  180
181   AAAAGGAAAA  AGGTTGTCCA  CATGAATAAA  CTCCGGAAAA  CCATTGGCCG  CCTGGAAGTC  240
241   AAGTGCAAGA  ACGCCGACGC  TGGCTGCATA  GTGACATGCC  CCCTGGCCCA  TCGCAAGGGG  300
301   CACCAGGACT  CATGCCCCTT  TGAGCTAACG  GCCTGCCCCA  ACGAGGGCTG  CACCTCGCAG  360
361   GTGCCGCGTG  GGACCCTGGC  AGAGCACCGG  CAGCATTGCC  AGCAAGGGTC  CCAGCAGCGC  420
421   TGCCCCCTGG  GCTGCGGGGC  CACCCTGGAC  CCGGCCGAGC  GTGCTCGCCA  CAACTGCTAC  480
481   CGGGAGCTGC  ACAACGCCTG  GAGCGTGCGC  CAGGAGCGCC  GTCGGCCCCT  GCTGCTGTCC  540
541   CTCCTGCGGC  GTGTGCGCTG  GCTGGACCAA  GCCACCAGTG  TCGTTCGTAG  AGAGCTGGCG  600
601   GAGCTCAGCA  ACTTCCTGGA  GGAAGACACC  GCTCTGCTGG  AGGGTGCCCC  ACAGGAGGAG  660
661   GCCGAGGCTG  CCCCAGAAGG  CAACGTTGGG  GCTGAGGTGG  TGGGGGAGCC  CAGGGCCAAC  720
721   ATACCTTGTA  AATAG  735

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Differentiation
Metal-binding
Nucleus
Reference proteome
Spermatogenesis
Zinc
Zinc-finger

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Molecular Function
Zinc ion binding
Biological Process
Cell differentiation
Biological Process
Spermatogenesis

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pap-2016Pan paniscus97.551e-136 392
LLPS-Pat-2850Pan troglodytes96.723e-133 383
LLPS-Gog-4659Gorilla gorilla96.334e-134 385
LLPS-Poa-2366Pongo abelii95.885e-127 367
LLPS-Mal-1972Mandrillus leucophaeus94.03e-27 106
LLPS-Ict-0993Ictidomys tridecemlineatus91.361e-39 140
LLPS-Cea-3821Cercocebus atys90.951e-129 375
LLPS-Maf-2689Macaca fascicularis90.612e-131 379
LLPS-Paa-3926Papio anubis90.612e-131 379
LLPS-Mam-1889Macaca mulatta90.612e-131 379
LLPS-Man-0556Macaca nemestrina90.21e-130 376
LLPS-Fec-0419Felis catus90.123e-39 137
LLPS-Rhb-3587Rhinopithecus bieti89.84e-130 375
LLPS-Nol-4212Nomascus leucogenys89.334e-114 334
LLPS-Chs-0504Chlorocebus sabaeus86.422e-126 366
LLPS-Dio-2546Dipodomys ordii83.461e-66 209
LLPS-Caj-0567Callithrix jacchus82.721e-35 128
LLPS-Eqc-1636Equus caballus80.02e-107 317
LLPS-Sus-3934Sus scrofa79.913e-108 319
LLPS-Aim-3456Ailuropoda melanoleuca79.421e-113 333
LLPS-Mup-4388Mustela putorius furo77.785e-111 327
LLPS-Urm-1222Ursus maritimus77.784e-73 228
LLPS-Ran-2818Rattus norvegicus77.734e-102 303
LLPS-Tut-1912Tursiops truncatus77.373e-102 304
LLPS-Caf-2040Canis familiaris77.376e-109 321
LLPS-Aon-3870Aotus nancymaae76.921e-105 313
LLPS-Loa-2164Loxodonta africana76.568e-103 305
LLPS-Mea-2512Mesocricetus auratus75.67e-97 290
LLPS-Mum-4019Mus musculus74.762e-95 287
LLPS-Ova-3190Ovis aries74.046e-96 288
LLPS-Myl-3126Myotis lucifugus73.085e-93 281
LLPS-Bot-3760Bos taurus73.081e-96 290
LLPS-Cas-1374Carlito syrichta73.082e-91 276
LLPS-Cap-1778Cavia porcellus72.24e-82 252
LLPS-Fud-1795Fukomys damarensis72.043e-89 270
LLPS-Mod-4321Monodelphis domestica66.839e-85 258
LLPS-Sah-2670Sarcophilus harrisii65.531e-82 253
LLPS-Meg-2012Meleagris gallopavo56.419e-0753.5
LLPS-Dos-1457Dothistroma septosporum55.02e-0651.6
LLPS-Leo-3850Lepisosteus oculatus52.855e-38 135
LLPS-Scf-3741Scleropages formosus49.383e-46 160
LLPS-Lac-3813Latimeria chalumnae49.289e-59 192
LLPS-Ten-1800Tetraodon nigroviridis48.543e-49 168
LLPS-Tar-1847Takifugu rubripes48.261e-48 166
LLPS-Icp-0534Ictalurus punctatus46.242e-49 169
LLPS-Dar-2217Danio rerio45.242e-47 163
LLPS-Orn-0313Oreochromis niloticus43.967e-49 166
LLPS-Scm-2397Scophthalmus maximus43.485e-49 168
LLPS-Asm-3946Astyanax mexicanus43.22e-50 171
LLPS-Gaa-1556Gasterosteus aculeatus42.513e-48 164
LLPS-Pof-3724Poecilia formosa42.035e-48 165
LLPS-Xim-2427Xiphophorus maculatus41.551e-47 164
LLPS-Orl-2439Oryzias latipes41.55e-45 157
LLPS-Lem-1262Leptosphaeria maculans34.174e-0857.4
LLPS-Anc-3135Anolis carolinensis34.153e-0960.8
LLPS-Orc-3910Oryctolagus cuniculus33.042e-0857.8
LLPS-Otg-1717Otolemur garnettii33.047e-0959.7
LLPS-Sem-0552Selaginella moellendorffii32.298e-0753.1
LLPS-Drm-0951Drosophila melanogaster32.082e-0652.4
LLPS-Xet-2932Xenopus tropicalis31.251e-0755.8
LLPS-Abg-0317Absidia glauca31.145e-1165.9
LLPS-Pes-3666Pelodiscus sinensis30.04e-0754.3
LLPS-Asf-1364Aspergillus flavus29.371e-0857.0
LLPS-Ora-1381Ornithorhynchus anatinus28.912e-0755.5
LLPS-Cis-0461Ciona savignyi28.572e-0651.6
LLPS-Tag-1630Taeniopygia guttata28.492e-0858.5
LLPS-Gaga-1541Gallus gallus28.492e-0858.2
LLPS-Cogr-1284Colletotrichum graminicola28.071e-0755.8
LLPS-Anp-0354Anas platyrhynchos28.021e-0858.5