LLPS-Hos-1199
NOP16
▼ OVERVIEW
Status: | Reviewed |
Protein Name: | Nucleolar protein 16; HBV pre-S2 trans-regulated protein 3 |
Gene Name: | NOP16, CGI-117, HSPC111 |
Ensembl Gene: | ENSG00000048162.20 |
Ensembl Protein: | ENSP00000478283.1 |
Organism: | Homo sapiens |
Taxa ID: | 9606 |
LLPS Type: | Others |
▼ Classification
Condensates:
Condensate | Description | Tissue/Cell | PMIDs |
---|---|---|---|
Nucleolus | "...SILAC-based approaches identified 351 proteins with 24 proteins showing at least a 2-fold change after infection." | HeLa cells | 19812395 |
Nucleolus | "...Finally, 221 proteins were found as nucleolar with No/Cyto > 1 and No/Nuc > 1." | HCT116 cells | 20026476 |
Nucleolus | "...Finally, 221 proteins were found as nucleolar with No/Cyto > 1 and No/Nuc > 1." | HCT116 cells | 20026476 |
Nucleolus | "...As a first step in elucidating these mechanisms we have carried out a proteomic analysis to draw up a list of proteins present within nucleoli of HeLa cells. This analysis allowed the identification of 213 different nucleolar proteins." | HeLa cells | 12429849 |
Nucleolus | "...In total, we identified 325 proteins localized to distinct nuclear bodies, including nucleoli, promyelocytic leukemia nuclear bodies, nuclear speckles, paraspeckles, Cajal bodies, Sam68 nuclear bodies, Polycomb bodies, and uncharacterized nuclear bodies." | HeLa cells | 24127217 |
Nucleolus | "...The data set from all our nucleolar mass spectrometry analyses defines an updated group of 692 proteins that reproducibly copurify with human nucleoli." | HeLa cells | 15635413 |
▼ CROSS REFERENCE
Database | Nucleotide ID | Protein ID |
---|---|---|
Ensembl | ENST00000616685.1 | ENSP00000478283.1 |
Ensembl | ENST00000621444.4 | ENSP00000479445.1 |
Ensembl | ENST00000509257.1 | ENSP00000427489.1 |
Ensembl | ENST00000502663.5 | ENSP00000423835.1 |
Ensembl | ENST00000619979.4 | ENSP00000484969.1 |
Ensembl | ENST00000618911.4 | ENSP00000483001.1 |
Ensembl | ENST00000614830.4 | ENSP00000480832.1 |
UniProt | Q9Y3C1, NOP16_HUMAN, B4DV13, D6RGD3, Q05D05, Q6IAI6, Q6PIM0, Q8IXL5 | |
GeneBank | CH471195, AK300883, AC138956, BC019331, BC032424, AF161460, KF459629, AY561704, AF151875, BC040106, CR457169 | AAH40106.1, AAH19331.1, AAD34112.1, AAH32424.1, BAG62525.1, EAW85085.1, AAS66977.1, EAW85084.1, AAF29075.1, CAG33450.1 |
RefSeq | NM_001256539.3, NM_001256540.3, NM_001291305.2, NM_001291307.2, NM_001291308.2, NM_001317975.1, NM_016391.7 | NP_001243468.2, NP_001243469.2, NP_001278234.1, NP_001278236.1, NP_001278237.1, NP_001304904.1, NP_057475.2 |
Entrez | 51491 |
▼ SEQUENCE
Protein Sequence (FASTA) |
---|
1 MPKAKGKTRR QKFGYSVNRK RLNRNARRKA APRIECSHIR HAWDHAKSVR QNLAEMGLAV 60 61 DPNRAVPLRK RKVKAMEVDI EERPKELVRK PYVLNDLEAE ASLPEKKGNT LSRDLIDYVR 120 121 YMVENHGEDY KQSGKTSSIL CRRGRWRWSD WFTSQLPQAE ASPGPVKLEP GCKARRCCVA 180 181 PEELARSHGI RRLHTRAHSP LWGRNCSQRL QFIFIWGFTE KPEPAVFRVG DVNIVCT 237 |
Nucleotide CDS Sequence (FASTA) |
1 Sequence u navailable 20 |
▼ ANNOTATION
Domain | ||||
SMART | LCR-eXXXplorer | CDD |
Drug | ||||
CTD |
Physicochemical | ||||
Compute pI/Mw | AAindex |
Function | ||||
PIRSF | CellMarker |
Localization | ||||
NLSdb |
Methylation | ||||
TCGA | ICGC | COSMIC | MethyCancer |
▼ ORTHOLOGY
DrLLPS ID | Organism | Identity | E-value | Score |
---|---|---|---|---|
LLPS-Pat-1176 | Pan troglodytes | 100.0 | 2e-75 | 233 |
LLPS-Poa-0159 | Pongo abelii | 98.47 | 9e-74 | 229 |
LLPS-Caf-1222 | Canis familiaris | 98.47 | 9e-75 | 231 |
LLPS-Mup-0630 | Mustela putorius furo | 97.71 | 3e-74 | 230 |
LLPS-Chs-3260 | Chlorocebus sabaeus | 97.71 | 6e-73 | 226 |
LLPS-Eqc-1852 | Equus caballus | 96.95 | 7e-74 | 229 |
LLPS-Aim-1905 | Ailuropoda melanoleuca | 96.18 | 3e-72 | 225 |
LLPS-Otg-1669 | Otolemur garnettii | 95.42 | 3e-73 | 228 |
LLPS-Fec-1442 | Felis catus | 95.42 | 3e-73 | 228 |
LLPS-Urm-0180 | Ursus maritimus | 94.74 | 1e-57 | 189 |
LLPS-Ova-1828 | Ovis aries | 94.66 | 4e-71 | 222 |
LLPS-Bot-2049 | Bos taurus | 94.66 | 4e-71 | 222 |
LLPS-Sus-1162 | Sus scrofa | 94.66 | 4e-70 | 219 |
LLPS-Cas-0653 | Carlito syrichta | 94.66 | 1e-71 | 223 |
LLPS-Ran-1221 | Rattus norvegicus | 93.89 | 6e-71 | 221 |
LLPS-Ict-2740 | Ictidomys tridecemlineatus | 93.23 | 1e-70 | 221 |
LLPS-Mum-1925 | Mus musculus | 93.13 | 2e-70 | 220 |
LLPS-Loa-2770 | Loxodonta africana | 93.13 | 1e-68 | 215 |
LLPS-Myl-1894 | Myotis lucifugus | 92.37 | 3e-69 | 217 |
LLPS-Dio-3142 | Dipodomys ordii | 92.37 | 1e-68 | 216 |
LLPS-Fud-3202 | Fukomys damarensis | 92.37 | 5e-70 | 219 |
LLPS-Aon-4661 | Aotus nancymaae | 92.37 | 1e-67 | 213 |
LLPS-Mal-2153 | Mandrillus leucophaeus | 92.15 | 7e-106 | 312 |
LLPS-Cap-0934 | Cavia porcellus | 90.84 | 2e-68 | 215 |
LLPS-Man-0374 | Macaca nemestrina | 89.66 | 1e-127 | 368 |
LLPS-Ora-0086 | Ornithorhynchus anatinus | 89.47 | 3e-25 | 100 |
LLPS-Orc-1711 | Oryctolagus cuniculus | 89.39 | 5e-64 | 204 |
LLPS-Pap-2995 | Pan paniscus | 89.12 | 2e-71 | 223 |
LLPS-Cea-1654 | Cercocebus atys | 88.14 | 7e-128 | 368 |
LLPS-Paa-2098 | Papio anubis | 87.61 | 2e-125 | 362 |
LLPS-Caj-1039 | Callithrix jacchus | 87.11 | 2e-98 | 294 |
LLPS-Maf-0218 | Macaca fascicularis | 85.96 | 1e-119 | 347 |
LLPS-Nol-3318 | Nomascus leucogenys | 85.2 | 2e-116 | 338 |
LLPS-Ere-0695 | Erinaceus europaeus | 83.95 | 2e-75 | 234 |
LLPS-Mea-0906 | Mesocricetus auratus | 83.47 | 3e-54 | 178 |
LLPS-Sah-0274 | Sarcophilus harrisii | 81.06 | 3e-59 | 192 |
LLPS-Mod-1332 | Monodelphis domestica | 80.45 | 5e-59 | 191 |
LLPS-Rhb-2421 | Rhinopithecus bieti | 79.91 | 3e-109 | 321 |
LLPS-Mam-2635 | Macaca mulatta | 77.53 | 7e-102 | 302 |
LLPS-Gaga-1480 | Gallus gallus | 72.99 | 1e-52 | 175 |
LLPS-Tag-0640 | Taeniopygia guttata | 67.88 | 2e-47 | 161 |
LLPS-Meg-2434 | Meleagris gallopavo | 67.8 | 2e-20 | 88.2 |
LLPS-Pes-0428 | Pelodiscus sinensis | 65.59 | 1e-33 | 124 |
LLPS-Anc-2412 | Anolis carolinensis | 64.44 | 3e-48 | 163 |
LLPS-Fia-1077 | Ficedula albicollis | 64.18 | 5e-44 | 152 |
LLPS-Gog-2768 | Gorilla gorilla | 64.14 | 7e-79 | 244 |
LLPS-Tut-1342 | Tursiops truncatus | 63.98 | 2e-53 | 178 |
LLPS-Lac-1714 | Latimeria chalumnae | 59.26 | 2e-45 | 156 |
LLPS-Leo-2633 | Lepisosteus oculatus | 56.3 | 1e-34 | 128 |
LLPS-Ten-0426 | Tetraodon nigroviridis | 55.56 | 4e-26 | 105 |
LLPS-Xet-0260 | Xenopus tropicalis | 54.4 | 4e-29 | 113 |
LLPS-Tar-2336 | Takifugu rubripes | 53.54 | 9e-26 | 104 |
LLPS-Orl-2411 | Oryzias latipes | 51.91 | 1e-25 | 103 |
LLPS-Orn-1154 | Oreochromis niloticus | 51.91 | 9e-31 | 117 |
LLPS-Xim-2029 | Xiphophorus maculatus | 48.48 | 3e-28 | 111 |
LLPS-Gaa-1326 | Gasterosteus aculeatus | 48.09 | 4e-25 | 102 |
LLPS-Scf-0047 | Scleropages formosus | 47.5 | 3e-23 | 99.0 |
LLPS-Pof-2019 | Poecilia formosa | 47.33 | 3e-28 | 111 |
LLPS-Dar-0947 | Danio rerio | 43.28 | 4e-19 | 86.3 |
LLPS-Cii-1399 | Ciona intestinalis | 41.84 | 4e-17 | 80.9 |
LLPS-Icp-1057 | Ictalurus punctatus | 41.73 | 4e-20 | 89.0 |
LLPS-Cis-1062 | Ciona savignyi | 40.15 | 1e-15 | 76.3 |
LLPS-Asm-1069 | Astyanax mexicanus | 39.06 | 2e-17 | 81.6 |