LLPS-Hos-1199
NOP16

▼ OVERVIEW


Status: Reviewed
Protein Name: Nucleolar protein 16; HBV pre-S2 trans-regulated protein 3
Gene Name: NOP16, CGI-117, HSPC111
Ensembl Gene: ENSG00000048162.20
Ensembl Protein: ENSP00000478283.1
Organism: Homo sapiens
Taxa ID: 9606
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...SILAC-based approaches identified 351 proteins with 24 proteins showing at least a 2-fold change after infection."
HeLa cells19812395
Nucleolus
"...Finally, 221 proteins were found as nucleolar with No/Cyto > 1 and No/Nuc > 1."
HCT116 cells20026476
Nucleolus
"...Finally, 221 proteins were found as nucleolar with No/Cyto > 1 and No/Nuc > 1."
HCT116 cells20026476
Nucleolus
"...As a first step in elucidating these mechanisms we have carried out a proteomic analysis to draw up a list of proteins present within nucleoli of HeLa cells. This analysis allowed the identification of 213 different nucleolar proteins."
HeLa cells12429849
Nucleolus
"...In total, we identified 325 proteins localized to distinct nuclear bodies, including nucleoli, promyelocytic leukemia nuclear bodies, nuclear speckles, paraspeckles, Cajal bodies, Sam68 nuclear bodies, Polycomb bodies, and uncharacterized nuclear bodies."
HeLa cells24127217
Nucleolus
"...The data set from all our nucleolar mass spectrometry analyses defines an updated group of 692 proteins that reproducibly copurify with human nucleoli."
HeLa cells15635413

▼ SEQUENCE


Protein Sequence (FASTA)
1     MPKAKGKTRR  QKFGYSVNRK  RLNRNARRKA  APRIECSHIR  HAWDHAKSVR  QNLAEMGLAV  60
61    DPNRAVPLRK  RKVKAMEVDI  EERPKELVRK  PYVLNDLEAE  ASLPEKKGNT  LSRDLIDYVR  120
121   YMVENHGEDY  KQSGKTSSIL  CRRGRWRWSD  WFTSQLPQAE  ASPGPVKLEP  GCKARRCCVA  180
181   PEELARSHGI  RRLHTRAHSP  LWGRNCSQRL  QFIFIWGFTE  KPEPAVFRVG  DVNIVCT  237
Nucleotide CDS Sequence (FASTA)
1     Sequence u  navailable  20

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pat-1176Pan troglodytes100.02e-75 233
LLPS-Poa-0159Pongo abelii98.479e-74 229
LLPS-Caf-1222Canis familiaris98.479e-75 231
LLPS-Mup-0630Mustela putorius furo97.713e-74 230
LLPS-Chs-3260Chlorocebus sabaeus97.716e-73 226
LLPS-Eqc-1852Equus caballus96.957e-74 229
LLPS-Aim-1905Ailuropoda melanoleuca96.183e-72 225
LLPS-Otg-1669Otolemur garnettii95.423e-73 228
LLPS-Fec-1442Felis catus95.423e-73 228
LLPS-Urm-0180Ursus maritimus94.741e-57 189
LLPS-Ova-1828Ovis aries94.664e-71 222
LLPS-Bot-2049Bos taurus94.664e-71 222
LLPS-Sus-1162Sus scrofa94.664e-70 219
LLPS-Cas-0653Carlito syrichta94.661e-71 223
LLPS-Ran-1221Rattus norvegicus93.896e-71 221
LLPS-Ict-2740Ictidomys tridecemlineatus93.231e-70 221
LLPS-Mum-1925Mus musculus93.132e-70 220
LLPS-Loa-2770Loxodonta africana93.131e-68 215
LLPS-Myl-1894Myotis lucifugus92.373e-69 217
LLPS-Dio-3142Dipodomys ordii92.371e-68 216
LLPS-Fud-3202Fukomys damarensis92.375e-70 219
LLPS-Aon-4661Aotus nancymaae92.371e-67 213
LLPS-Mal-2153Mandrillus leucophaeus92.157e-106 312
LLPS-Cap-0934Cavia porcellus90.842e-68 215
LLPS-Man-0374Macaca nemestrina89.661e-127 368
LLPS-Ora-0086Ornithorhynchus anatinus89.473e-25 100
LLPS-Orc-1711Oryctolagus cuniculus89.395e-64 204
LLPS-Pap-2995Pan paniscus89.122e-71 223
LLPS-Cea-1654Cercocebus atys88.147e-128 368
LLPS-Paa-2098Papio anubis87.612e-125 362
LLPS-Caj-1039Callithrix jacchus87.112e-98 294
LLPS-Maf-0218Macaca fascicularis85.961e-119 347
LLPS-Nol-3318Nomascus leucogenys85.22e-116 338
LLPS-Ere-0695Erinaceus europaeus83.952e-75 234
LLPS-Mea-0906Mesocricetus auratus83.473e-54 178
LLPS-Sah-0274Sarcophilus harrisii81.063e-59 192
LLPS-Mod-1332Monodelphis domestica80.455e-59 191
LLPS-Rhb-2421Rhinopithecus bieti79.913e-109 321
LLPS-Mam-2635Macaca mulatta77.537e-102 302
LLPS-Gaga-1480Gallus gallus72.991e-52 175
LLPS-Tag-0640Taeniopygia guttata67.882e-47 161
LLPS-Meg-2434Meleagris gallopavo67.82e-2088.2
LLPS-Pes-0428Pelodiscus sinensis65.591e-33 124
LLPS-Anc-2412Anolis carolinensis64.443e-48 163
LLPS-Fia-1077Ficedula albicollis64.185e-44 152
LLPS-Gog-2768Gorilla gorilla64.147e-79 244
LLPS-Tut-1342Tursiops truncatus63.982e-53 178
LLPS-Lac-1714Latimeria chalumnae59.262e-45 156
LLPS-Leo-2633Lepisosteus oculatus56.31e-34 128
LLPS-Ten-0426Tetraodon nigroviridis55.564e-26 105
LLPS-Xet-0260Xenopus tropicalis54.44e-29 113
LLPS-Tar-2336Takifugu rubripes53.549e-26 104
LLPS-Orl-2411Oryzias latipes51.911e-25 103
LLPS-Orn-1154Oreochromis niloticus51.919e-31 117
LLPS-Xim-2029Xiphophorus maculatus48.483e-28 111
LLPS-Gaa-1326Gasterosteus aculeatus48.094e-25 102
LLPS-Scf-0047Scleropages formosus47.53e-2399.0
LLPS-Pof-2019Poecilia formosa47.333e-28 111
LLPS-Dar-0947Danio rerio43.284e-1986.3
LLPS-Cii-1399Ciona intestinalis41.844e-1780.9
LLPS-Icp-1057Ictalurus punctatus41.734e-2089.0
LLPS-Cis-1062Ciona savignyi40.151e-1576.3
LLPS-Asm-1069Astyanax mexicanus39.062e-1781.6