LLPS-Hos-1136
BTRC
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | F-box/WD repeat-containing protein 1A; E3RSIkappaB; Epididymis tissue protein Li 2a; F-box and WD repeats protein beta-TrCP; pIkappaBalpha-E3 receptor subunit |
| Gene Name: | BTRC, BTRCP, FBW1A, FBXW1A |
| Ensembl Gene: | ENSG00000166167.17 |
| Ensembl Protein: | ENSP00000385339.2 |
| Organism: | Homo sapiens |
| Taxa ID: | 9606 |
| LLPS Type: | Regulator |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| PML nuclear body | "...The F-box protein β-TrCP promotes ubiquitination of TRF1 and regulates the ALT-associated PML bodies formation in U2OS cells." | U2OS cells | 23583392 |
| PML nuclear body | "...These results reveal that β-TrCP1 is involved in the negative regulation of TRF1 and represents a new pathway for APB formation in telomerase-negative cells." | U2OS cells | 23583392 |
| P-body | "...β-TrCP modulates P-body formation." | HeLa Flp-In T-REx cells | 25900982 |
▼ FUNCTION
| Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins (PubMed:10066435, PubMed:10497169, PubMed:10644755, PubMed:10835356, PubMed:11238952, PubMed:11359933, PubMed:11994270, PubMed:12791267, PubMed:12902344, PubMed:14603323, PubMed:14681206, PubMed:14988407, PubMed:15448698, PubMed:15917222, PubMed:16371461, PubMed:25503564, PubMed:25704143, PubMed:9859996, PubMed:22087322). SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling (PubMed:12077367, PubMed:12820959). SCF(BTRC) mediates the ubiquitination of phosphorylated NFKB1, ATF4, CDC25A, DLG1, FBXO5, PER1, SMAD3, SMAD4, SNAI1 and probably NFKB2 (PubMed:10835356, PubMed:11238952, PubMed:14681206, PubMed:14603323). SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription (PubMed:10066435, PubMed:10497169, PubMed:10644755). Ubiquitination of NFKBIA occurs at 'Lys-21' and 'Lys-22' (PubMed:10066435). SCF(BTRC) mediates the ubiquitination of CEP68; this is required for centriole separation during mitosis (PubMed:25704143, PubMed:25503564). SCF(BTRC) mediates the ubiquitination and subsequent degradation of nuclear NFE2L1 (By similarity). Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and PER2 (PubMed:15917222). May be involved in ubiquitination and subsequent proteasomal degradation through a DBB1-CUL4 E3 ubiquitin-protein ligase. Required for activation of NFKB-mediated transcription by IL1B, MAP3K14, MAP3K1, IKBKB and TNF. Required for proteolytic processing of GLI3 (PubMed:16371461). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENST00000408038.6 | ENSP00000385339.2 |
| Ensembl | ENST00000393441.8 | ENSP00000377088.5 |
| Ensembl | ENST00000370187.7 | ENSP00000359206.3 |
| Ensembl | ENST00000370183.2 | ENSP00000359202.2 |
| UniProt | Q9Y297, FBW1A_HUMAN, B5MD49, Q5W141, Q5W142, Q9Y213 | |
| GeneBank | CH471066, GU727631, BC027994, AL627424, AL445463, AF101784, AK313353, AF129530, Y14153, AL133387 | CAA74572.1, ADU87633.1, EAW49772.1, EAW49774.1, BAG36155.1, AAF04464.1, AAH27994.1, AAD08702.1 |
| RefSeq | NM_003939.4, NM_033637.3 | NP_003930.1, NP_378663.1 |
| Entrez | 8945 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDPAEAVLQE KALKFMCSMP RSLWLGCSSL ADSMPSLRCL YNPGTGALTA FQNSSEREDC 60 61 NNGEPPRKII PEKNSLRQTY NSCARLCLNQ ETVCLASTAM KTENCVAKTK LANGTSSMIV 120 121 PKQRKLSASY EKEKELCVKY FEQWSESDQV EFVEHLISQM CHYQHGHINS YLKPMLQRDF 180 181 ITALPARGLD HIAENILSYL DAKSLCAAEL VCKEWYRVTS DGMLWKKLIE RMVRTDSLWR 240 241 GLAERRGWGQ YLFKNKPPDG NAPPNSFYRA LYPKIIQDIE TIESNWRCGR HSLQRIHCRS 300 301 ETSKGVYCLQ YDDQKIVSGL RDNTIKIWDK NTLECKRILT GHTGSVLCLQ YDERVIITGS 360 361 SDSTVRVWDV NTGEMLNTLI HHCEAVLHLR FNNGMMVTCS KDRSIAVWDM ASPTDITLRR 420 421 VLVGHRAAVN VVDFDDKYIV SASGDRTIKV WNTSTCEFVR TLNGHKRGIA CLQYRDRLVV 480 481 SGSSDNTIRL WDIECGACLR VLEGHEELVR CIRFDNKRIV SGAYDGKIKV WDLVAALDPR 540 541 APAGTLCLRT LVEHSGRVFR LQFDEFQIVS SSHDDTILIW DFLNDPAAQA EPPRSPSRTY 600 601 TYISR 605 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGACCCGG CCGAGGCGGT GCTGCAAGAG AAGGCACTCA AGTTTATGTG CTCTATGCCC 60 61 AGGTCTCTGT GGCTGGGCTG CTCCAGCCTG GCGGACAGCA TGCCTTCGCT GCGATGCCTG 120 121 TATAACCCAG GGACTGGCGC ACTCACAGCT TTCCAGACAT ACAACAGCTG TGCCAGACTC 180 181 TGCTTAAACC AAGAAACAGT ATGTTTAGCA AGCACTGCTA TGAAGACTGA GAATTGTGTG 240 241 GCCAAAACAA AACTTGCCAA TGGCACTTCC AGTATGATTG TGCCCAAGCA ACGGAAACTC 300 301 TCAGCAAGCT ATGAAAAGGA AAAGGAACTG TGTGTCAAAT ACTTTGAGCA GTGGTCAGAG 360 361 TCAGATCAAG TGGAATTTGT GGAACATCTT ATATCCCAAA TGTGTCATTA CCAACATGGG 420 421 CACATAAACT CGTATCTTAA ACCTATGTTG CAGAGAGATT TCATAACTGC TCTGCCAGCT 480 481 CGGGGATTGG ATCATATTGC TGAGAACATT CTGTCATACC TGGATGCCAA ATCACTATGT 540 541 GCTGCTGAAC TTGTGTGCAA GGAATGGTAC CGAGTGACCT CTGATGGCAT GCTGTGGAAG 600 601 AAGCTTATCG AGAGAATGGT CAGGACAGAT TCTCTGTGGA GAGGCCTGGC AGAACGAAGA 660 661 GGATGGGGAC AGTATTTATT CAAAAACAAA CCTCCTGACG GGAATGCTCC TCCCAACTCT 720 721 TTTTATAGAG CACTTTATCC TAAAATTATA CAAGACATTG AGACAATAGA ATCTAATTGG 780 781 AGATGTGGAA GACATAGTTT ACAGAGAATT CACTGCCGAA GTGAAACAAG CAAAGGAGTT 840 841 TACTGTTTAC AGTATGATGA TCAGAAAATA GTAAGCGGCC TTCGAGACAA CACAATCAAG 900 901 ATCTGGGATA AAAACACATT GGAATGCAAG CGAATTCTCA CAGGCCATAC AGGTTCAGTC 960 961 CTCTGTCTCC AGTATGATGA GAGAGTGATC ATAACAGGAT CATCGGATTC CACGGTCAGA 1020 1021 GTGTGGGATG TAAATACAGG TGAAATGCTA AACACGTTGA TTCACCATTG TGAAGCAGTT 1080 1081 CTGCACTTGC GTTTCAATAA TGGCATGATG GTGACCTGCT CCAAAGATCG TTCCATTGCT 1140 1141 GTATGGGATA TGGCCTCCCC AACTGACATT ACCCTCCGGA GGGTGCTGGT CGGACACCGA 1200 1201 GCTGCTGTCA ATGTTGTAGA CTTTGATGAC AAGTACATTG TTTCTGCATC TGGGGATAGA 1260 1261 ACTATAAAGG TATGGAACAC AAGTACTTGT GAATTTGTAA GGACCTTAAA TGGACACAAA 1320 1321 CGAGGCATTG CCTGTTTGCA GTACAGGGAC AGGCTGGTAG TGAGTGGCTC ATCTGACAAC 1380 1381 ACTATCAGAT TATGGGACAT AGAATGTGGT GCATGTTTAC GAGTGTTAGA AGGCCATGAG 1440 1441 GAATTGGTGC GTTGTATTCG ATTTGATAAC AAGAGGATAG TCAGTGGGGC CTATGATGGA 1500 1501 AAAATTAAAG TGTGGGATCT TGTGGCTGCT TTGGACCCCC GTGCTCCTGC AGGGACACTC 1560 1561 TGTCTACGGA CCCTTGTGGA GCATTCCGGA AGAGTTTTTC GACTACAGTT TGATGAATTC 1620 1621 CAGATTGTCA GTAGTTCACA TGATGACACA ATCCTCATCT GGGACTTCCT AAATGATCCA 1680 1681 GCTGCCCAAG CTGAACCCCC CCGTTCCCCT TCTCGAACAT ACACCTACAT CTCCAGATAA 1740 |
▼ KEYWORD
ID | Family |
3D-structure | |
Alternative splicing | |
Biological rhythms | |
Complete proteome | |
Cytoplasm | |
Host-virus interaction | |
Ligase | |
Nucleus | |
Polymorphism | |
Reference proteome | |
Repeat | |
Ubl conjugation pathway | |
WD repeat | |
Wnt signaling pathway
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Nucleoplasm | |
Cellular Component | Pwp2p-containing subcomplex of 90S preribosome | |
Cellular Component | SCF ubiquitin ligase complex | |
Cellular Component | Small-subunit processome | |
Molecular Function | Beta-catenin binding | |
Molecular Function | Ligase activity | |
Molecular Function | Protein dimerization activity | |
Molecular Function | Protein phosphorylated amino acid binding | |
Molecular Function | Ubiquitin protein ligase activity | |
Molecular Function | Ubiquitin-protein transferase activity | |
Biological Process | Branching involved in mammary gland duct morphogenesis | |
Biological Process | Cellular response to organic cyclic compound | |
Biological Process | G2/M transition of mitotic cell cycle | |
Biological Process | Interleukin-1-mediated signaling pathway | |
Biological Process | Mammary gland epithelial cell proliferation | |
Biological Process | Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
Biological Process | Negative regulation of DNA-binding transcription factor activity | |
Biological Process | Negative regulation of smoothened signaling pathway | |
Biological Process | Negative regulation of transcription, DNA-templated | |
Biological Process | NIK/NF-kappaB signaling | |
Biological Process | Positive regulation of circadian rhythm | |
Biological Process | Positive regulation of proteolysis | |
Biological Process | Positive regulation of transcription, DNA-templated | |
Biological Process | Post-translational protein modification | |
Biological Process | Proteasome-mediated ubiquitin-dependent protein catabolic process | |
Biological Process | Protein dephosphorylation | |
Biological Process | Protein destabilization | |
Biological Process | Protein polyubiquitination | |
Biological Process | Protein ubiquitination | |
Biological Process | Regulation of canonical Wnt signaling pathway | |
Biological Process | Regulation of circadian rhythm | |
Biological Process | Regulation of I-kappaB kinase/NF-kappaB signaling | |
Biological Process | Regulation of mitotic cell cycle phase transition | |
Biological Process | Regulation of proteasomal protein catabolic process | |
Biological Process | Rhythmic process | |
Biological Process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | |
Biological Process | Signal transduction | |
Biological Process | Stress-activated MAPK cascade | |
Biological Process | Ubiquitin-dependent protein catabolic process | |
Biological Process | Viral process | |
Biological Process | Wnt signaling pathway |
▼ ANNOTATION
| Drug | ||||
| CTD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Localization | ||||
| COMPARTMENTS | ||||
| Methylation | ||||
| TCGA | ICGC | MethyCancer | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Cea-2546 | Cercocebus atys | 100.0 | 0.0 | 1263 |
| LLPS-Maf-1434 | Macaca fascicularis | 100.0 | 0.0 | 1263 |
| LLPS-Chs-2823 | Chlorocebus sabaeus | 100.0 | 0.0 | 1263 |
| LLPS-Mal-0236 | Mandrillus leucophaeus | 100.0 | 0.0 | 1263 |
| LLPS-Paa-1891 | Papio anubis | 100.0 | 0.0 | 1263 |
| LLPS-Rhb-1818 | Rhinopithecus bieti | 100.0 | 0.0 | 1263 |
| LLPS-Man-2309 | Macaca nemestrina | 100.0 | 0.0 | 1263 |
| LLPS-Mam-1957 | Macaca mulatta | 100.0 | 0.0 | 1226 |
| LLPS-Gog-3113 | Gorilla gorilla | 99.83 | 0.0 | 1261 |
| LLPS-Orc-1962 | Oryctolagus cuniculus | 99.83 | 0.0 | 1261 |
| LLPS-Pap-2798 | Pan paniscus | 99.83 | 0.0 | 1261 |
| LLPS-Pat-2791 | Pan troglodytes | 99.83 | 0.0 | 1261 |
| LLPS-Fec-2751 | Felis catus | 99.83 | 0.0 | 1261 |
| LLPS-Nol-1361 | Nomascus leucogenys | 99.83 | 0.0 | 1261 |
| LLPS-Caf-2082 | Canis familiaris | 99.83 | 0.0 | 1261 |
| LLPS-Caj-2279 | Callithrix jacchus | 99.67 | 0.0 | 1258 |
| LLPS-Aim-2167 | Ailuropoda melanoleuca | 99.67 | 0.0 | 1260 |
| LLPS-Mup-3849 | Mustela putorius furo | 99.64 | 0.0 | 1149 |
| LLPS-Otg-0320 | Otolemur garnettii | 99.6 | 0.0 | 1037 |
| LLPS-Mod-2964 | Monodelphis domestica | 99.34 | 0.0 | 1254 |
| LLPS-Ict-2495 | Ictidomys tridecemlineatus | 99.34 | 0.0 | 1256 |
| LLPS-Eqc-3271 | Equus caballus | 99.34 | 0.0 | 1255 |
| LLPS-Ova-2107 | Ovis aries | 99.02 | 0.0 | 1047 |
| LLPS-Myl-4005 | Myotis lucifugus | 99.01 | 0.0 | 1036 |
| LLPS-Loa-0950 | Loxodonta africana | 98.82 | 0.0 | 1224 |
| LLPS-Cas-0751 | Carlito syrichta | 98.81 | 0.0 | 1221 |
| LLPS-Mum-3482 | Mus musculus | 98.68 | 0.0 | 1249 |
| LLPS-Fia-3433 | Ficedula albicollis | 98.64 | 0.0 | 1212 |
| LLPS-Anp-2231 | Anas platyrhynchos | 98.6 | 0.0 | 1024 |
| LLPS-Aon-3109 | Aotus nancymaae | 98.51 | 0.0 | 1236 |
| LLPS-Tag-1638 | Taeniopygia guttata | 98.51 | 0.0 | 1244 |
| LLPS-Ran-4187 | Rattus norvegicus | 98.47 | 0.0 | 1211 |
| LLPS-Meg-0271 | Meleagris gallopavo | 97.33 | 0.0 | 1217 |
| LLPS-Cap-2526 | Cavia porcellus | 96.43 | 0.0 | 1172 |
| LLPS-Pes-2125 | Pelodiscus sinensis | 95.96 | 0.0 | 1182 |
| LLPS-Ora-3021 | Ornithorhynchus anatinus | 95.67 | 0.0 | 1233 |
| LLPS-Gaga-3936 | Gallus gallus | 95.06 | 0.0 | 1234 |
| LLPS-Sah-3223 | Sarcophilus harrisii | 94.79 | 0.0 | 1239 |
| LLPS-Sus-1854 | Sus scrofa | 94.66 | 0.0 | 1133 |
| LLPS-Bot-4547 | Bos taurus | 93.72 | 0.0 | 1166 |
| LLPS-Lac-3966 | Latimeria chalumnae | 90.18 | 0.0 | 945 |
| LLPS-Dio-3056 | Dipodomys ordii | 88.8 | 0.0 | 1087 |
| LLPS-Urm-1401 | Ursus maritimus | 87.7 | 0.0 | 920 |
| LLPS-Fud-4304 | Fukomys damarensis | 83.74 | 0.0 | 920 |
| LLPS-Tut-2380 | Tursiops truncatus | 83.74 | 0.0 | 922 |
| LLPS-Orn-3736 | Oreochromis niloticus | 81.55 | 0.0 | 875 |
| LLPS-Gaa-3272 | Gasterosteus aculeatus | 80.78 | 0.0 | 865 |
| LLPS-Ten-3633 | Tetraodon nigroviridis | 80.66 | 0.0 | 872 |
| LLPS-Tar-3472 | Takifugu rubripes | 80.46 | 0.0 | 872 |
| LLPS-Mea-1118 | Mesocricetus auratus | 77.36 | 0.0 | 957 |
| LLPS-Orl-1989 | Oryzias latipes | 74.92 | 0.0 | 912 |
| LLPS-Xim-1452 | Xiphophorus maculatus | 74.79 | 0.0 | 909 |
| LLPS-Pof-1710 | Poecilia formosa | 74.79 | 0.0 | 909 |
| LLPS-Scf-1694 | Scleropages formosus | 74.75 | 0.0 | 906 |
| LLPS-Icp-0983 | Ictalurus punctatus | 73.81 | 0.0 | 909 |
| LLPS-Dar-3715 | Danio rerio | 73.76 | 0.0 | 905 |
| LLPS-Asm-1900 | Astyanax mexicanus | 73.75 | 0.0 | 906 |
| LLPS-Scm-2395 | Scophthalmus maximus | 73.1 | 0.0 | 899 |
| LLPS-Cae-1454 | Caenorhabditis elegans | 63.71 | 0.0 | 636 |
| LLPS-Miv-1114 | Microbotryum violaceum | 42.69 | 2e-73 | 258 |
| LLPS-Cii-2308 | Ciona intestinalis | 41.38 | 1e-32 | 132 |
| LLPS-Nec-1031 | Neurospora crassa | 41.37 | 7e-47 | 180 |
| LLPS-Asf-0969 | Aspergillus flavus | 40.51 | 6e-13 | 76.3 |
| LLPS-Tum-1367 | Tuber melanosporum | 39.74 | 3e-53 | 199 |
| LLPS-Asni-0872 | Aspergillus niger | 39.7 | 6e-51 | 192 |
| LLPS-Cis-1737 | Ciona savignyi | 38.67 | 2e-08 | 61.6 |
| LLPS-Map-0765 | Magnaporthe poae | 38.64 | 2e-13 | 77.4 |
| LLPS-Gag-1025 | Gaeumannomyces graminis | 38.64 | 3e-13 | 77.4 |
| LLPS-Fus-0019 | Fusarium solani | 37.77 | 2e-45 | 177 |
| LLPS-Cogr-0656 | Colletotrichum graminicola | 37.29 | 1e-47 | 184 |
| LLPS-Spr-0562 | Sporisorium reilianum | 36.46 | 8e-11 | 69.7 |
| LLPS-Fuv-1255 | Fusarium verticillioides | 36.33 | 1e-43 | 171 |
| LLPS-Fuo-1601 | Fusarium oxysporum | 36.33 | 1e-43 | 171 |
| LLPS-Scj-0289 | Schizosaccharomyces japonicus | 36.21 | 8e-16 | 84.7 |
| LLPS-Asn-0399 | Aspergillus nidulans | 36.07 | 3e-46 | 179 |
| LLPS-Trv-1582 | Trichoderma virens | 36.07 | 8e-36 | 141 |
| LLPS-Mao-1133 | Magnaporthe oryzae | 35.71 | 2e-06 | 55.1 |
| LLPS-Yal-0659 | Yarrowia lipolytica | 35.65 | 1e-09 | 64.7 |
| LLPS-Aso-1287 | Aspergillus oryzae | 35.56 | 7e-15 | 82.4 |
| LLPS-Ast-1180 | Aspergillus terreus | 35.56 | 5e-15 | 83.2 |
| LLPS-Abg-0038 | Absidia glauca | 34.89 | 7e-71 | 244 |
| LLPS-Zyt-0757 | Zymoseptoria tritici | 34.79 | 8e-53 | 197 |
| LLPS-Drm-2193 | Drosophila melanogaster | 34.75 | 4e-67 | 243 |
| LLPS-Ved-0860 | Verticillium dahliae | 33.97 | 1e-46 | 181 |
| LLPS-Php-2319 | Physcomitrella patens | 33.89 | 4e-33 | 133 |
| LLPS-Scs-0583 | Sclerotinia sclerotiorum | 33.51 | 3e-44 | 173 |
| LLPS-Leo-3341 | Lepisosteus oculatus | 33.33 | 1e-37 | 150 |
| LLPS-Usm-1372 | Ustilago maydis | 33.33 | 1e-34 | 144 |
| LLPS-Beb-1554 | Beauveria bassiana | 33.26 | 2e-56 | 208 |
| LLPS-Scc-0494 | Schizosaccharomyces cryophilus | 32.62 | 6e-75 | 254 |
| LLPS-Dos-1439 | Dothistroma septosporum | 32.61 | 4e-50 | 191 |
| LLPS-Scp-1210 | Schizosaccharomyces pombe | 32.08 | 3e-72 | 247 |
| LLPS-Poa-2785 | Pongo abelii | 31.82 | 2e-19 | 94.7 |
| LLPS-Mel-1266 | Melampsora laricipopulina | 31.69 | 2e-17 | 89.4 |
| LLPS-Phn-0838 | Phaeosphaeria nodorum | 31.43 | 1e-17 | 91.3 |
| LLPS-Trr-1556 | Trichoderma reesei | 31.19 | 3e-40 | 162 |
| LLPS-Anc-1312 | Anolis carolinensis | 31.16 | 9e-35 | 140 |
| LLPS-Nef-1276 | Neosartorya fischeri | 30.83 | 2e-12 | 74.7 |
| LLPS-Sac-0645 | Saccharomyces cerevisiae | 30.57 | 3e-18 | 93.2 |
| LLPS-Kop-1485 | Komagataella pastoris | 30.22 | 2e-09 | 64.7 |
| LLPS-Xet-0111 | Xenopus tropicalis | 30.14 | 3e-34 | 139 |
| LLPS-Pug-1052 | Puccinia graminis | 30.11 | 3e-07 | 58.2 |
| LLPS-Chc-0712 | Chondrus crispus | 30.0 | 2e-30 | 132 |
| LLPS-Asfu-0923 | Aspergillus fumigatus | 30.0 | 8e-12 | 72.8 |
| LLPS-Asg-0941 | Ashbya gossypii | 29.89 | 4e-17 | 89.4 |
| LLPS-Asc-1431 | Aspergillus clavatus | 29.69 | 1e-52 | 197 |
| LLPS-Crn-1400 | Cryptococcus neoformans | 29.51 | 1e-15 | 85.1 |
| LLPS-Pyt-0826 | Pyrenophora teres | 29.48 | 4e-42 | 167 |
| LLPS-Blg-1129 | Blumeria graminis | 29.29 | 2e-16 | 87.8 |
| LLPS-Lem-1547 | Leptosphaeria maculans | 29.19 | 1e-41 | 166 |
| LLPS-Pytr-0843 | Pyrenophora triticirepentis | 28.9 | 2e-40 | 162 |
| LLPS-Coo-0092 | Colletotrichum orbiculare | 28.66 | 3e-33 | 140 |
| LLPS-Cog-1425 | Colletotrichum gloeosporioides | 28.66 | 1e-33 | 141 |