LLPS-Hos-0675
RPL9P9

▼ OVERVIEW

Status: Reviewed
Protein Name: 60S ribosomal protein L9; Large ribosomal subunit protein uL6
Gene Name: RPL9P9, OK/SW-cl.103
Ensembl Gene: ENSG00000163682.16
Ensembl Protein: ENSP00000494697.1
Organism: Homo sapiens
Taxa ID: 9606
LLPS Type: LLPS regulator
PDB: 2CQL (A) More


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...SILAC-based approaches identified 351 proteins with 24 proteins showing at least a 2-fold change after infection."
HeLa cells19812395
Nucleolus
"...As a first step in elucidating these mechanisms we have carried out a proteomic analysis to draw up a list of proteins present within nucleoli of HeLa cells. This analysis allowed the identification of 213 different nucleolar proteins."
HeLa cells12429849
Nucleolus
"...The data set from all our nucleolar mass spectrometry analyses defines an updated group of 692 proteins that reproducibly copurify with human nucleoli."
HeLa cells15635413
Postsynaptic density
"...We report the first direct comparison of the proteome of triplicate isolates of mouse and human cortical postsynaptic densities. The mouse postsynaptic density comprised 1556 proteins and the human one 1461."
Human cortex23071613

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKTILSNQTV  DIPENGMRLD  VFYLHLYCTF  QALCGLTSVF  SLLVDITLKG  RTVIVKGPRG  60
61    TLRRDFNHIN  VELSLLGKKK  KRLRVDKWWG  NRKELATVRT  ICSHVQNMIK  GVTLGFRYKM  120
121   RSVYAHFPIN  VVIQENGSLV  EIRNFLGEKY  IRRVRMRPGV  ACSVSQAQKD  ELILEGNDIE  180
181   LVSNSAALIQ  QATTVKNKDI  RKFLDGIYVS  EKGTVQQADE  220
Nucleotide CDS Sequence (FASTA)
1     ATGAAGACTA  TTCTCAGCAA  TCAGACTGTC  GACATTCCAG  AAAATGTCGA  CATTACTCTG  60
61    AAGGGACGCA  CAGTTATCGT  GAAGGGCCCC  AGAGGAACCC  TGCGGAGGGA  CTTCAATCAC  120
121   ATCAATGTAG  AACTCAGCCT  TCTTGGAAAG  AAAAAAAAGA  GGCTCCGGGT  TGACAAATGG  180
181   TGGGGTAACA  GAAAGGAACT  GGCTACCGTT  CGGACTATTT  GTAGTCATGT  ACAGAACATG  240
241   ATCAAGGGTG  TTACACTGGG  CTTCCGTTAC  AAGATGAGGT  CTGTGTATGC  TCACTTCCCC  300
301   ATCAACGTTG  TTATCCAGGA  GAATGGGTCT  CTTGTTGAAA  TCCGAAATTT  CTTGGGTGAA  360
361   AAATATATCC  GCAGGGTTCG  GATGAGACCA  GGTGTTGCTT  GTTCAGTATC  TCAAGCCCAG  420
421   AAAGATGAAT  TAATCCTTGA  AGGAAATGAC  ATTGAGCTTG  TTTCAAATTC  AGCGGCTTTG  480
481   ATTCAGCAAG  CCACAACAGT  TAAAAACAAG  GATATCAGGA  AATTTTTGGA  TGGTATCTAT  540
541   GTCTCTGAAA  AAGGAACTGT  TCAGCAGGCT  GATGAATAA  579

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anp-0293Anas platyrhynchos96.01e-112 327
LLPS-Chs-0779Chlorocebus sabaeus94.715e-120 346
LLPS-Tar-0303Takifugu rubripes88.72e-102 301
LLPS-Paa-0958Papio anubis87.273e-122 352
LLPS-Mal-1493Mandrillus leucophaeus87.273e-122 352
LLPS-Cea-2115Cercocebus atys87.273e-122 352
LLPS-Aon-1319Aotus nancymaae87.273e-122 352
LLPS-Sus-0105Sus scrofa87.273e-122 352
LLPS-Gog-1285Gorilla gorilla87.273e-122 352
LLPS-Caj-0245Callithrix jacchus87.277e-122 352
LLPS-Caf-1419Canis familiaris87.273e-122 352
LLPS-Poa-0373Pongo abelii87.273e-122 352
LLPS-Eqc-0056Equus caballus87.273e-122 352
LLPS-Nol-0231Nomascus leucogenys87.273e-122 352
LLPS-Pap-0163Pan paniscus87.273e-122 352
LLPS-Pat-1535Pan troglodytes87.273e-122 352
LLPS-Fec-0648Felis catus87.273e-122 352
LLPS-Man-1172Macaca nemestrina87.273e-122 352
LLPS-Dio-2406Dipodomys ordii86.824e-121 349
LLPS-Bot-0029Bos taurus86.822e-121 350
LLPS-Myl-0927Myotis lucifugus86.824e-121 349
LLPS-Ova-0643Ovis aries86.822e-121 350
LLPS-Aim-1979Ailuropoda melanoleuca86.821e-120 348
LLPS-Ict-3206Ictidomys tridecemlineatus86.824e-121 349
LLPS-Urm-0209Ursus maritimus86.822e-121 350
LLPS-Loa-1518Loxodonta africana86.821e-121 350
LLPS-Otg-1399Otolemur garnettii86.823e-121 349
LLPS-Rhb-0324Rhinopithecus bieti86.821e-119 345
LLPS-Ran-0433Rattus norvegicus86.365e-120 346
LLPS-Mum-0180Mus musculus86.362e-120 347
LLPS-Cap-0751Cavia porcellus86.364e-120 346
LLPS-Cas-0394Carlito syrichta86.363e-121 349
LLPS-Orc-0811Oryctolagus cuniculus86.361e-121 350
LLPS-Mea-1696Mesocricetus auratus85.913e-120 347
LLPS-Maf-2338Macaca fascicularis85.913e-122 352
LLPS-Fud-0812Fukomys damarensis85.912e-119 345
LLPS-Mod-1039Monodelphis domestica85.912e-120 347
LLPS-Tut-0592Tursiops truncatus85.587e-114 330
LLPS-Sah-0529Sarcophilus harrisii85.452e-120 347
LLPS-Mam-1120Macaca mulatta85.01e-118 343
LLPS-Pes-0765Pelodiscus sinensis84.552e-119 345
LLPS-Ora-0005Ornithorhynchus anatinus84.095e-118 341
LLPS-Ere-0269Erinaceus europaeus83.243e-93 277
LLPS-Fia-0001Ficedula albicollis83.181e-117 340
LLPS-Mup-0395Mustela putorius furo82.733e-114 332
LLPS-Gaga-0407Gallus gallus82.733e-118 342
LLPS-Anc-0008Anolis carolinensis82.733e-116 337
LLPS-Tag-0457Taeniopygia guttata82.333e-111 323
LLPS-Meg-1465Meleagris gallopavo82.272e-117 340
LLPS-Xet-2050Xenopus tropicalis80.916e-114 331
LLPS-Lac-0170Latimeria chalumnae80.06e-110 321
LLPS-Leo-1217Lepisosteus oculatus79.095e-112 326
LLPS-Dar-1461Danio rerio79.01e-110 322
LLPS-Scf-0830Scleropages formosus78.646e-111 323
LLPS-Icp-1724Ictalurus punctatus78.081e-109 320
LLPS-Pof-0798Poecilia formosa77.273e-109 319
LLPS-Orl-1084Oryzias latipes76.362e-106 313
LLPS-Orn-1252Oreochromis niloticus76.361e-106 312
LLPS-Asm-2255Astyanax mexicanus75.127e-106 310
LLPS-Ten-0205Tetraodon nigroviridis75.06e-105 308
LLPS-Xim-0012Xiphophorus maculatus74.556e-104 305
LLPS-Gaa-1018Gasterosteus aculeatus74.091e-102 302
LLPS-Scm-0991Scophthalmus maximus71.811e-81 250
LLPS-Mua-0250Musa acuminata69.391e-37 132
LLPS-Cii-0584Ciona intestinalis68.022e-76 236
LLPS-Cis-0510Ciona savignyi63.843e-72 224
LLPS-Orgl-0851Oryza glumaepatula61.958e-38 144
LLPS-Cae-0083Caenorhabditis elegans61.755e-73 226
LLPS-Chr-0473Chlamydomonas reinhardtii60.236e-60 193
LLPS-Orb-2283Oryza barthii58.935e-60 194
LLPS-Gas-0286Galdieria sulphuraria57.395e-64 204
LLPS-Phn-1149Phaeosphaeria nodorum57.352e-45 155
LLPS-Scj-1480Schizosaccharomyces japonicus56.49e-57 185
LLPS-Drm-0705Drosophila melanogaster56.282e-76 235
LLPS-Abg-1259Absidia glauca56.252e-55 181
LLPS-Trv-0711Trichoderma virens55.112e-54 179
LLPS-Mel-0468Melampsora laricipopulina54.914e-53 176
LLPS-Coc-1251Corchorus capsularis54.757e-59 190
LLPS-Scp-0389Schizosaccharomyces pombe54.248e-59 190
LLPS-Gag-0309Gaeumannomyces graminis54.242e-54 179
LLPS-Map-0295Magnaporthe poae54.244e-54 178
LLPS-Osl-0303Ostreococcus lucimarinus54.171e-53 177
LLPS-Scc-0050Schizosaccharomyces cryophilus53.984e-55 181
LLPS-Put-0537Puccinia triticina53.711e-53 177
LLPS-Lem-0408Leptosphaeria maculans53.376e-54 177
LLPS-Mao-0507Magnaporthe oryzae53.373e-57 186
LLPS-Ved-0849Verticillium dahliae53.331e-52 174
LLPS-Pug-0290Puccinia graminis53.113e-54 179
LLPS-Blg-0102Blumeria graminis53.071e-52 174
LLPS-Aso-0788Aspergillus oryzae52.843e-50 168
LLPS-Asf-0257Aspergillus flavus52.843e-50 168
LLPS-Cogr-0750Colletotrichum graminicola52.811e-52 175
LLPS-Fus-0161Fusarium solani52.783e-54 179
LLPS-Scs-0615Sclerotinia sclerotiorum52.573e-50 168
LLPS-Asc-0045Aspergillus clavatus52.273e-48 163
LLPS-Asni-1041Aspergillus niger52.271e-50 169
LLPS-Asfu-0891Aspergillus fumigatus52.279e-51 169
LLPS-Ast-0419Aspergillus terreus52.279e-50 167
LLPS-Nef-0485Neosartorya fischeri52.272e-50 169
LLPS-Tum-0249Tuber melanosporum52.254e-56 183
LLPS-Usm-0641Ustilago maydis51.812e-51 171
LLPS-Spr-0425Sporisorium reilianum51.814e-51 171
LLPS-Fuv-0211Fusarium verticillioides51.674e-53 176
LLPS-Php-0565Physcomitrella patens51.631e-63 202
LLPS-Sac-1325Saccharomyces cerevisiae51.162e-48 163
LLPS-Yal-0351Yarrowia lipolytica51.167e-52 172
LLPS-Zem-0538Zea mays51.161e-63 202
LLPS-Pyt-0947Pyrenophora teres51.142e-50 169
LLPS-Crn-0727Cryptococcus neoformans51.056e-51 170
LLPS-Dac-1046Daucus carota50.924e-63 201
LLPS-Amt-1993Amborella trichopoda50.914e-64 204
LLPS-Beb-0487Beauveria bassiana50.763e-53 176
LLPS-Via-0589Vigna angularis50.697e-62 198
LLPS-Vir-0161Vigna radiata50.697e-62 198
LLPS-Glm-0453Glycine max50.691e-61 197
LLPS-Sob-0059Sorghum bicolor50.691e-64 205
LLPS-Met-0012Medicago truncatula50.681e-61 197
LLPS-Phv-1016Phaseolus vulgaris50.466e-62 198
LLPS-Sot-0916Solanum tuberosum50.455e-63 201
LLPS-Hea-1479Helianthus annuus50.451e-64 205
LLPS-Trr-1074Trichoderma reesei50.255e-53 175
LLPS-Sei-1959Setaria italica50.233e-59 191
LLPS-Sem-1123Selaginella moellendorffii50.235e-65 206
LLPS-Pot-1918Populus trichocarpa50.233e-63 202
LLPS-Orbr-0654Oryza brachyantha50.231e-62 202
LLPS-Cus-0528Cucumis sativus50.01e-62 200
LLPS-Sol-0219Solanum lycopersicum50.08e-62 198
LLPS-Brn-0748Brassica napus50.01e-60 195
LLPS-Pytr-1326Pyrenophora triticirepentis50.01e-44 154
LLPS-Bro-0384Brassica oleracea50.04e-61 196
LLPS-Brr-0130Brassica rapa50.04e-61 196
LLPS-Lep-2235Leersia perrieri49.772e-63 202
LLPS-Hov-0192Hordeum vulgare49.771e-62 201
LLPS-Tra-2330Triticum aestivum49.777e-63 201
LLPS-Ori-0456Oryza indica49.772e-63 202
LLPS-Orni-0728Oryza nivara49.772e-63 202
LLPS-Orr-0224Oryza rufipogon49.772e-63 202
LLPS-Tru-0005Triticum urartu49.771e-62 200
LLPS-Viv-1948Vitis vinifera49.773e-64 204
LLPS-Ors-0887Oryza sativa49.772e-63 202
LLPS-Orp-0663Oryza punctata49.772e-63 202
LLPS-Miv-0405Microbotryum violaceum49.732e-52 174
LLPS-Mae-0408Manihot esculenta49.554e-63 201
LLPS-Nia-0590Nicotiana attenuata49.552e-62 200
LLPS-Arl-0251Arabidopsis lyrata49.541e-60 195
LLPS-Art-1334Arabidopsis thaliana49.541e-60 195
LLPS-Brd-0054Brachypodium distachyon49.316e-63 201
LLPS-Org-0435Oryza glaberrima49.311e-62 200
LLPS-Prp-0210Prunus persica49.18e-62 198
LLPS-Gor-0225Gossypium raimondii49.14e-62 199
LLPS-Coo-0224Colletotrichum orbiculare48.178e-56 182
LLPS-Nec-0583Neurospora crassa47.954e-56 183
LLPS-Chc-0221Chondrus crispus47.492e-58 189
LLPS-Kop-0409Komagataella pastoris47.066e-54 177
LLPS-Asn-0389Aspergillus nidulans47.034e-52 173
LLPS-Orm-0410Oryza meridionalis46.552e-59 192
LLPS-Cog-0407Colletotrichum gloeosporioides46.122e-53 178
LLPS-Dos-1046Dothistroma septosporum45.215e-49 165
LLPS-Cym-0131Cyanidioschyzon merolae44.811e-48 164
LLPS-Asg-0052Ashbya gossypii44.292e-50 169
LLPS-Zyt-0345Zymoseptoria tritici43.895e-52 173
LLPS-Thc-0115Theobroma cacao39.852e-51 173