LLPS-Hos-0252
MRPS15

▼ OVERVIEW

Status: Reviewed
Protein Name: 28S ribosomal protein S15, mitochondrial
Gene Name: MRPS15, RPMS15, DC37
Ensembl Gene: ENSG00000116898.11
Ensembl Protein: ENSP00000362208.5
Organism: Homo sapiens
Taxa ID: 9606
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...In total, we identified 325 proteins localized to distinct nuclear bodies, including nucleoli, promyelocytic leukemia nuclear bodies, nuclear speckles, paraspeckles, Cajal bodies, Sam68 nuclear bodies, Polycomb bodies, and uncharacterized nuclear bodies."
HeLa cells24127217

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLRVAWRTLS  LIRTRAVTQV  LVPGLPGGGS  AKFPFNQWGL  QPRSLLLQAA  RGYVVRKPAQ  60
61    SRLDDDPPPS  TLLKDYQNVP  GIEKVDDVVK  RLLSLEMANK  KEMLKIKQEQ  FMKKIVANPE  120
121   DTRSLEARII  ALSVKIRSYE  EHLEKHRKDK  AHKRYLLMSI  DQRKKMLKNL  RNTNYDVFEK  180
181   ICWGLGIEYT  FPPLYYRRAH  RRFVTKKALC  IRVFQETQKL  KKRRRALKAA  AAAQKQAKRR  240
241   NPDSPAKAIP  KTLKDSQ  257
Nucleotide CDS Sequence (FASTA)
1     ATGCTGAGGG  TCGCGTGGAG  GACGCTGAGT  TTGATTCGGA  CCCGGGCAGT  TACCCAGGTC  60
61    CTAGTACCCG  GGCTGCCGGG  CGGTGGGAGC  GCCAAGTTTC  CTTTCAACCA  GTGGGGCCTG  120
121   CAGCCTCGAA  GTCTCCTCCT  CCAGGCCGCG  CGCGGATATG  TCGTCCGGAA  ACCAGCCCAG  180
181   TCTAGGCTGG  ATGATGACCC  ACCTCCCTCT  ACGCTGCTCA  AAGACTACCA  GAATGTCCCT  240
241   GGAATTGAGA  AGGTTGATGA  TGTCGTGAAA  AGACTCTTGT  CTTTGGAAAT  GGCCAACAAG  300
301   AAGGAGATGC  TAAAAATCAA  GCAAGAACAG  TTTATGAAGA  AGATTGTTGC  AAACCCAGAG  360
361   GACACCAGAT  CCCTGGAGGC  TCGAATTATT  GCCTTGTCTG  TCAAGATCCG  CAGTTATGAA  420
421   GAACACTTGG  AGAAACATCG  AAAGGACAAA  GCCCACAAAC  GCTATCTGCT  AATGAGCATT  480
481   GACCAGAGGA  AAAAGATGCT  CAAAAACCTC  CGTAACACCA  ACTATGATGT  CTTTGAGAAG  540
541   ATATGCTGGG  GGCTGGGAAT  TGAGTACACC  TTCCCCCCTC  TGTATTACCG  AAGAGCCCAC  600
601   CGCCGATTCG  TGACCAAGAA  GGCTCTGTGC  ATTCGGGTTT  TCCAGGAGAC  TCAAAAGCTG  660
661   AAGAAGCGAA  GAAGAGCCTT  AAAGGCTGCA  GCAGCAGCCC  AAAAACAAGC  AAAGCGGAGG  720
721   AACCCAGACA  GCCCTGCCAA  AGCCATACCA  AAGACACTCA  AAGACAGCCA  ATAA  774

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pap-2725Pan paniscus98.441e-165 466
LLPS-Pat-2165Pan troglodytes98.054e-164 462
LLPS-Gog-3614Gorilla gorilla97.283e-164 462
LLPS-Nol-1638Nomascus leucogenys93.394e-154 437
LLPS-Chs-4534Chlorocebus sabaeus87.942e-143 409
LLPS-Rhb-0010Rhinopithecus bieti87.167e-141 403
LLPS-Cea-0354Cercocebus atys87.165e-142 406
LLPS-Mal-2363Mandrillus leucophaeus86.772e-141 404
LLPS-Maf-3201Macaca fascicularis86.778e-141 403
LLPS-Mam-3967Macaca mulatta85.991e-135 390
LLPS-Paa-1910Papio anubis85.68e-139 398
LLPS-Aon-2991Aotus nancymaae83.271e-135 390
LLPS-Caj-3703Callithrix jacchus82.954e-133 384
LLPS-Man-2823Macaca nemestrina80.936e-123 357
LLPS-Otg-1590Otolemur garnettii76.653e-127 369
LLPS-Cas-0667Carlito syrichta76.261e-123 359
LLPS-Ora-1915Ornithorhynchus anatinus75.823e-79 244
LLPS-Cap-2445Cavia porcellus74.653e-117 343
LLPS-Orc-2825Oryctolagus cuniculus73.932e-119 349
LLPS-Ova-2006Ovis aries72.592e-120 352
LLPS-Caf-3191Canis familiaris72.191e-87 265
LLPS-Loa-4575Loxodonta africana71.884e-115 338
LLPS-Ict-4104Ictidomys tridecemlineatus71.543e-119 348
LLPS-Bot-2285Bos taurus70.666e-116 340
LLPS-Fec-4765Felis catus70.274e-116 340
LLPS-Ere-0996Erinaceus europaeus69.942e-67 213
LLPS-Sah-1805Sarcophilus harrisii69.893e-81 251
LLPS-Eqc-1581Equus caballus69.887e-119 347
LLPS-Dio-3380Dipodomys ordii69.236e-37 134
LLPS-Sus-2854Sus scrofa67.653e-105 313
LLPS-Fud-1077Fukomys damarensis67.589e-109 322
LLPS-Tut-2139Tursiops truncatus66.84e-112 330
LLPS-Urm-2946Ursus maritimus66.674e-92 280
LLPS-Mea-0130Mesocricetus auratus65.69e-102 304
LLPS-Mum-4636Mus musculus64.683e-95 287
LLPS-Aim-0678Ailuropoda melanoleuca64.345e-108 320
LLPS-Myl-1436Myotis lucifugus63.954e-103 307
LLPS-Ran-0173Rattus norvegicus63.183e-97 292
LLPS-Mod-3183Monodelphis domestica58.61e-77 242
LLPS-Xet-2856Xenopus tropicalis58.243e-58 192
LLPS-Gaa-1786Gasterosteus aculeatus58.05e-55 181
LLPS-Pes-3568Pelodiscus sinensis55.561e-51 173
LLPS-Leo-2755Lepisosteus oculatus55.063e-55 183
LLPS-Orn-1353Oreochromis niloticus54.788e-51 173
LLPS-Lac-4096Latimeria chalumnae54.366e-62 202
LLPS-Anc-3122Anolis carolinensis53.411e-54 182
LLPS-Pof-4176Poecilia formosa53.165e-48 166
LLPS-Tar-1145Takifugu rubripes52.873e-44 155
LLPS-Xim-3102Xiphophorus maculatus52.872e-50 172
LLPS-Ten-2867Tetraodon nigroviridis52.633e-43 153
LLPS-Icp-3132Ictalurus punctatus52.543e-53 179
LLPS-Scm-2629Scophthalmus maximus51.855e-51 174
LLPS-Asm-2830Astyanax mexicanus51.144e-50 171
LLPS-Fia-2047Ficedula albicollis50.572e-50 171
LLPS-Meg-0460Meleagris gallopavo49.441e-50 172
LLPS-Scf-3592Scleropages formosus48.117e-47 163
LLPS-Anp-2413Anas platyrhynchos46.36e-52 176
LLPS-Gaga-0130Gallus gallus45.762e-29 114
LLPS-Orl-1355Oryzias latipes44.551e-48 167
LLPS-Dar-1209Danio rerio41.942e-50 172
LLPS-Drm-2038Drosophila melanogaster34.093e-1371.2
LLPS-Cis-0976Ciona savignyi25.62e-0754.3