LLPS-Gog-a366
CNN3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Calponin |
| Gene Name: | CNN3 |
| Ensembl Gene: | ENSGGOG00000013870.3 |
| Ensembl Protein: | ENSGGOP00000036016.1 |
| Organism: | Gorilla gorilla |
| Taxa ID: | 9595 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSGGOT00000053809.1 | ENSGGOP00000036016.1 |
| Ensembl | ENSGGOT00000029128.2 | ENSGGOP00000022268.2 |
| Ensembl | ENSGGOT00000013915.3 | ENSGGOP00000013526.2 |
| UniProt | G3RDC6, G3RDC6_GORGO | |
| GeneBank | CABD030004664 | |
| RefSeq | XM_004026169.2 | XP_004026218.1 |
| Entrez | 101135340 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTHFNKGPSY GLSAEVKNKI ASKYDHQAEE DLRNWIEEVT GMSIGTNFQL GLKDGIILCE 60 61 LINKLQPGSV KKVNESSLNW PQLENIGNFI KAIQAYGMKP HDIFEANDLF ENGNMTQVQT 120 121 TLVALAGLAK TKGFHTTIDI GVKYAEKQTR RFDEGKLKAG QSVIGLQMGT NKCASQAGMT 180 181 AYGTRRHLYD PKMQTDKPFD QTTISLQMGT NKGASQAGML APGTRRDIYD QKLTLQPVDN 240 241 STISLQMGTN KVASQKGMSV YGLGRQVYDP KYCAAPTEPV IHNGSQGTGT NGSEISDSDY 300 301 QAEYPDEYHG EYQDDYPRDY QYSDQGIDY 329 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACCCACT TCAACAAGGG CCCTTCCTAC GGGCTCTCGG CCGAAGTCAA GAACAAGATT 60 61 GCTTCCAAGT ATGATCATCA GGCAGAAGAA GATCTTCGCA ATTGGATAGA AGAGGTGACA 120 121 GGCATGAGCA TTGGCACCAA CTTCCAGCTG GGCTTAAAGG ATGGCATCAT CCTCTGCGAA 180 181 CTTATAAACA AGCTACAGCC AGGCTCAGTG AAGAAGGTCA ACGAGTCCTC ACTGAACTGG 240 241 CCTCAGTTGG AGAATATTGG CAACTTTATT AAAGCTATTC AGGCTTATGG TATGAAGCCA 300 301 CATGACATAT TCGAAGCAAA TGATCTTTTT GAGAATGGAA ACATGACCCA GGTTCAGACT 360 361 ACTCTGGTGG CTCTAGCAGG TCTGGCTAAA ACAAAAGGAT TCCATACAAC CATTGACATT 420 421 GGAGTTAAGT ATGCAGAAAA ACAAACAAGA CGTTTTGATG AAGGAAAATT AAAAGCTGGC 480 481 CAAAGTGTAA TTGGTCTGCA GATGGGAACC AACAAATGTG CCAGCCAGGC AGGTATGACA 540 541 GCTTACGGGA CTAGGAGGCA TCTTTATGAT CCCAAAATGC AAACTGACAA ACCTTTTGAC 600 601 CAGACCACAA TTAGTCTGCA GATGGGCACT AATAAAGGAG CCAGCCAGGC AGGGATGTTA 660 661 GCACCAGGTA CCAGAAGAGA CATCTATGAT CAGAAGCTAA CATTACAGCC GGTGGACAAC 720 721 TCGACAATTT CCCTACAGAT GGGTACCAAC AAAGTTGCTT CCCAGAAAGG AATGAGTGTG 780 781 TATGGGCTTG GGCGGCAAGT ATATGATCCC AAATACTGTG CTGCTCCTAC AGAACCTGTC 840 841 ATTCACAACG GAAGCCAAGG AACAGGAACA AATGGTTCGG AAATCAGTGA TAGTGATTAT 900 901 CAGGCAGAAT ACCCTGATGA GTATCATGGC GAGTACCAGG ATGACTACCC CAGAGATTAC 960 961 CAATATAGCG ACCAAGGCAT TGATTATTAG 990 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Actin cytoskeleton | |
Cellular Component | Cytosol | |
Molecular Function | Actin binding | |
Molecular Function | Calmodulin binding | |
Biological Process | Actomyosin structure organization | |
Biological Process | Epithelial cell differentiation |