LLPS-Gog-a1016
NDUFA12
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Complex I-B17.2; CI-B17.2; CIB17.2; NADH-ubiquinone oxidoreductase subunit B17.2 |
| Gene Name: | NDUFA12 |
| Ensembl Gene: | ENSGGOG00000012880.3 |
| Ensembl Protein: | ENSGGOP00000012562.3 |
| Organism: | Gorilla gorilla |
| Taxa ID: | 9595 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSGGOT00000012924.3 | ENSGGOP00000012562.3 |
| Ensembl | ENSGGOT00000059449.1 | ENSGGOP00000038433.1 |
| UniProt | Q0MQ86, NDUAC_GORGO | |
| GeneBank | DQ885748 | ABH12257.1 |
| RefSeq | NM_001279616.1 | NP_001266545.1 |
| Entrez | 101148753 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MELVQVLKRG LQQITGHGGL RGYLRVFFRT NDAKVGTLVG EDKYGNKYYE DNKQFFGRHR 60 61 WVVYTTEMNG KNTFWDVDGS MVPPEWHRWL HSMTDDPPTT KPLTARKFIW TNHKFNMTGT 120 121 PEQYVPYSTT RKKIQEWIPP STPYK 145 |
| Nucleotide CDS Sequence (FASTA) |
1 CAGCGGGGCA AGATGGAGTT AGTGCAGGTC CTGAAACGCG GGCTGCAGCA GATCACCGGC 60 61 CACGGCGGTC TCCGAGGCTA TCTACGGGTT TTTTTCAGGA CAAATGATGC GAAGGTTGGT 120 121 ACATTAGTGG GGGAAGACAA ATATGGAAAC AAATACTATG AAGACAACAA GCAATTTTTT 180 181 GGCCGTCACC GATGGGTTGT ATATACTACT GAAATGAATG GCAAAAACAC ATTCTGGGAT 240 241 GTGGATGGAA GCATGGTGCC TCCTGAATGG CATCGTTGGC TTCACAGTAT GACTGATGAT 300 301 CCTCCAACGA CAAAACCACT TACTGCTCGT AAATTCATTT GGACAAACCA TAAATTCAAC 360 361 ATGACTGGCA CCCCAGAACA ATATGTACCT TATTCTACCA CTAGAAAGAA GATTCAGGAG 420 421 TGGATCCCAC CTTCAACACC TTACAAGTAA 450 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Mitochondrial respiratory chain complex I | |
Molecular Function | Electron transfer activity | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Biological Process | Mitochondrial ATP synthesis coupled electron transport | |
Biological Process | Response to oxidative stress |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mum-a1030 | Mus musculus | 7e-95 | 279 | undefined |
| LLPS-Hos-a1045 | Homo sapiens | 2e-103 | 301 | undefined |