LLPS-Gog-a002
HECW1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| Gene Name: | HECW1 |
| Ensembl Gene: | ENSGGOG00000024448.2 |
| Ensembl Protein: | ENSGGOP00000018999.2 |
| Organism: | Gorilla gorilla |
| Taxa ID: | 9595 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSGGOT00000026678.2 | ENSGGOP00000018999.2 |
| Ensembl | ENSGGOT00000045201.1 | ENSGGOP00000033196.1 |
| UniProt | A0A2I2YE72, A0A2I2YE72_GORGO | |
| GeneBank | CABD030050988, CABD030050984, CABD030050981, CABD030050982, CABD030050987, CABD030050980, CABD030050986, CABD030050985, CABD030050983 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 FLLYLCSHHN LYQNRFLGLA AMASPSRNSQ SRRRCKEPLR YSYNPDQFHN MDLRGGPHDG 60 61 VTIPRSTSDT DLVTSDSRST LMVSSSYYSI GHSQDLVIHW DIKEEVDAGD WIGMYLIDEV 120 121 LSENFLDYKN RGVNGSHRGQ IIWKIDASSY FVEPETKICF KYYHGVSGAL RATTPSVTVK 180 181 NSAAPIFKSI GADETVQGQG SRRLISFSLS DFQAMGLKKG MFFNPDPYLK ISIQPGKHSI 240 241 FPALPHHGQE RRSKIIGNTV NPIWQAEQFS FVSLPTDVLE IEVKDKFAKS RPIIKRFLGK 300 301 LSMPVQRLLE RHAIGDRVVS YTLGRRLPTD HVSGQLQFRF EITSSIHPDD EEISLSTEPE 360 361 SAQIQDSPMN NLMESSSGEP RSEAPESSES WKPEQLGEGS VPDGPGNQSM ELSRPAEEAA 420 421 VITEAGDQGM VSVGPEEAGE LLAQVQKDIQ PAPSAEELAE QLDLGEEASA LLLEDGEAPA 480 481 STKEEPLEEE AMTQSRAGRE EEEKEQEEEG DVSTLEQGEG RLQLRASVKR KSRPCSLPVS 540 541 ELETVIASAC GDPETPRTHY IRIHTLLHSM PSAQGGSAAE EEDGAEEEST LKDSSEKDGL 600 601 SEVDTVAADP SALEEDREEP EGATPGTAHP GHSGGHFPSL ANGAAQDGDT HPSTGSESDS 660 661 SPRQGGDHSC EGCDASCCSP SCYSSSCYST SCYSSSCYSA SCYSPSCYNG NRFASHTRFS 720 721 SVDSAKISES TVFSSQDDEE EENSAFESVP DSMQSPELDP ESTNGAGPWQ DELAAPSGHV 780 781 ERSPEGLESP VAGPSNRREG ECPILHNSQP VSQLPSLRPE HHHYPTIDEP LPPKILVLLI 840 841 VLAILQFFTD FSNYLIQSFG PQGRTIATER SEEDSGSQSC EQAPAGGGGG GGSDSEAESS 900 901 QSSLDLRREG SLSPVNSQKI TLLLQSPAVK FITNPEFFTV LHANYSAYRV FTSSTCLKHM 960 961 ILKVRRDARN FERYQHNRDL VNFINMFADT RLELPRGWEI KTDQQGKSFF VDHNSRATTF 1020 1021 IDPRIPLQNG RLPNHLTHRQ HLQRLRSYSA GEASEVSRNR GASLLARPGH SLVAAIRSQH 1080 1081 QHESLPLAYN DKIVAFLRQP NIFEMLQERQ PSLARNHTLR EKIHYIRTEG NHGLEKLSCD 1140 1141 ADLVILLSLF EEEIMSYVPL QAAFHPGYSF SPRCSPCSSP QNSPGLQRAS ARAPSPYRRD 1200 1201 FEAKLRNFYR KLEAKGFGQG PGKIKLIIRR DHLLEGTFNQ VMAYSRKELQ RNKLYVTFVG 1260 1261 EEGLDYSGPS REFFFLLSQE LFNPYYGLFE YSANDTYTVQ ISPMSAFVEN HLEWFRFSGR 1320 1321 ILGLALIHQY LLDAFFTRPF YKALLRLPCF QPSPEFHQSL QWMKDNNITD ILDLTFTVNE 1380 1381 EVFGQVTERE LKSGGANTQV TEKNKKEYIE RMVKWRVERG VVQQTEALVR GFYEVVDSRL 1440 1441 VSVFDARELE LVIAGTAEID LNDWRNNTEY RGGYHDGHLV IRWFWAAVER FNNEQRLRLL 1500 1501 QFVTGTSSVP YEGFAALRGS NGLRRFCIEK WGKITSLPRA HTCFNRLDLP PYPSYSMLYE 1560 1561 KLLTAVEETS TFGLE 1575 |
| Nucleotide CDS Sequence (FASTA) |
1 GATTTCCAAG CCATGGGGTT GAAGAAAGGG ATGTTTTTCA ACCCAGACCC TTATCTGAAG 60 61 ATTTCCATTC AGCCTGGGAA ACACAGCATC TTCCCCGCCC TCCCTCACCA TGGGCAGGAG 120 121 AGGAGATCCA AGATCATAGG CAACACCGTG AACCCCATCT GGCAGGCCGA GCAATTCAGT 180 181 TTTGTGTCCT TGCCCACTGA CGTGCTGGAA ATTGAGGTGA AGGACAAGTT TGCCAAGAGC 240 241 CGCCCCATCA TCAAGCGCTT CTTGGGAAAG CTGTCGATGC CCGTTCAAAG ACTCCTGGAG 300 301 AGACACGCCA TAGGGGATAG GGTGGTCAGC TACACACTTG GCCGCAGGCT TCCAACAGAT 360 361 CATGTGAGTG GACAGCTGCA ATTCCGATTT GAGATCACTT CCTCCATCCA CCCAGTGACT 420 421 TGCACTAATG CATTTGAAAT GGGGAATTTC ACATCTGTCA GGAATCCAGT AGAACAGCTG 480 481 CAGGAAGCAG ATGATGAGGA GATTTCCCTG AGTACCGAGC CTGAGTCAGC CCAAATTCAG 540 541 GACAGCCCCA TGAACAACCT GATGGAAAGC AGCAGTGGGG AACCTCGGTC TGAGGCACCA 600 601 GAGTCCTCTG AGAGCTGGAA GCCAGAGCAG CTGGGTGAGG GCAGTGTCCC CGATGGTCCA 660 661 GGGAACCAAA GCATGGAGCT TTCCAGACCA GCTGAGGAAG CAGCAGTCAT CACGGAGGCA 720 721 GGAGACCAGG GCATGGTCTC TGTGGGACCT GAAGAGGCTG GGGAGCTCCT GGCCCAGGTG 780 781 CAAAAGGACA TCCAGCCTGC CCCCAGTGCA GAAGAGCTGG CCGAGCAGCT GGACCTGGGT 840 841 GAGGAGGCGT CAGCACTGCT GCTGGAAGAC GGTGAAGCCC CAGCCAGCAC CAAGGAGGAG 900 901 CCCTTGGAGG AGGAAGCAAT GACCCAGAGC CGGGCTGGCA TCCACACCCT GCTGCACAGC 960 961 ATGCCCTCCG CCCAGGGCGG CAGCGCGGCA GAGGAGGAGG ACGGCGCGGA GGAGGAGTCC 1020 1021 ACCCTCAAGG ACTCCTCGGA GAAGGATGGG CTCAGCGAGG TGGACACGGT GGCCGCTGAC 1080 1081 CCGTCTGCCC TGGAAGAGGA CAGAGAAGAG CCCGAGGGGG CTACTCCAGG CACGGCGCAC 1140 1141 CCTGGCCACT CCGGGGGCCA CTTCCCCAGC CTGGCCAATG GCGCGGCCCA GGATGGCGAC 1200 1201 ACGCACCCCA GCACCGGGAG CGAGAGCGAC TCCAGCCCCA GGCAAGGCGG GGACCACAGT 1260 1261 TGCGAGGGCT GTGACGCGTC CTGCTGCAGC CCCTCGTGCT ACAGCTCCTC GTGCTACAAC 1320 1321 ACGCGCTTCT CCTCCGTGGA CAGCGCCAAG ATCTCCGAGA GCACGGTCTT CTCCTCGCAA 1380 1381 GACGACGAGG AGGAGGAGAA CAGCGCGTTC GAGTCGGTAC CCGACTCCAT GCAGAGCCCT 1440 1441 GAGCTGGACC CGGAGTCCAC GAACGGCGCT GGGCCGTGGC CAGATGTAAT GCACTGGGCG 1500 1501 CAGGAAGAGG GAGTGGCATC AGACAAAAAA CTCACATCCT TGCCCTTTAG AGGCCAACAG 1560 1561 TCTAGCAGGT GGAAGAGCAG GAAGTGTTTC AGGGTCACAG TGGACATCTC TGCATTGGCA 1620 1621 CTGGCAGTTT CTAAAGAAAT GTCTAAGTTC CTGAACTCTG CAGAGTGTAA ACCACCAAGT 1680 1681 GAGGGTTCTT CCAGGCAGAC AAGCAGTGAG GGTGAATGTC CTATACTCCA TAATTCCCAG 1740 1741 CCAGTAAGCC AGCTTCCTTC CCTGAGGCCT GAACATCATC ACTACCCAAC AATCGATGAG 1800 1801 CCTCTTCCAC CAACTTGGGA AGCAATCACC CACTCAAAAG GAAAGAATTT TTATATTCGT 1860 1861 CACACCATCA CATCACAAAA AGTCTCCAGC CACCCATCAC CAAGAGTTTT GGCCCCCAAG 1920 1921 GAGCAAACCA AATCTTTCCA TTTTCTAATG CAAAGGTATC AAAACATTCA GCGAACCATT 1980 1981 GCAACAGAGA GGTCCGAAGA AGATTCTGGC AGCCAAAGAG AGGAACCTGG GAGTGAAGAG 2040 2041 GTTTTCCAGC ATGCCACAGG AGATCTAAGG AGAGAAGGGT CACTTTCTCC AGTGAACTCA 2100 2101 CAAAAAATCA CCTTGCTGCT GCAGTCCCCA GCGGTCAAGT TCATCACCAA CCCTGAGTTC 2160 2161 TTCACTGTGC TGCACGCCAA TTATAGTGCC TACCGAGTCT TCACCAGTAG CACCTGCTTA 2220 2221 AAGCACATGA TTCTGAAAGT CCGACGGGAT GCTCGCAATT TTGAACGCTA CCAGCACAAC 2280 2281 CGGGACTTGG TGAATTTCAT CAATATGTTC GCAGACACTC GGCTGGAACT GCCCCGGGGC 2340 2341 TGGGAGATCA AAACGGACCA GCAGGGAAAG TCTTTTTTCG TGGACCACAA CAGTCGAGCT 2400 2401 ACCACTTTCA TTGACCCCCG AATCCCTCTT CAGAACGGTC GTCTTCCCAA TCATCTAACT 2460 2461 CACCGACAGC ACCTCCAGAG GCTCCGAAGT TACAGCGCTG GAGAGGCCTC AGAAGTTTCT 2520 2521 AGAAACAGAG GAGCCTCTTT ACTGGCCAGG CCAGGACACA GCTTAGTAGC TGCTATTCGA 2580 2581 AGCCAACATC AACATGAGTC ATTGCCACTG GCATATAATG ACAAGATTGT GGCATTTCTT 2640 2641 CGCCAGCCAA ACATTTTTGA AATGCTGCAA GAGCGTCAGC CAAGCTTAGC AAGAAACCAC 2700 2701 ACACTCAGGG AGAAAATCCA TTACATTCGG ACTGAGGGTA ATCACGGGCT TGAGAAGTTG 2760 2761 TCCTGTGATG CGGATCTGGT CATTTTGCTG AGATGCAGTC TCTTTGAAGA AGAGATTATG 2820 2821 TCCTACGTCC CCCTGCAGGC TGCCTTCCAC CCTGGGTATA GCTTCTCTCC CCGCTGTTCA 2880 2881 CCCTGTTCTT CACCTCAGAA CTCCCCAGCA GGTTTACAGA GAGCCAGTGC AAGAGCCCCT 2940 2941 TCCCCCTACC GGAGAGACTT TGAGGCCAAG CTCCGCAATT TCTACAGAAA ACTGGAAGCC 3000 3001 AAAGGATTTG GTCAGGGTCC GGGGAAAATT AAGCTCATTA TTCGCCGGGA TCATTTGTTG 3060 3061 GAGGGAACCT TCAATCAGGT GATGGCCTAT TCGCGGAAAG AGCTCCAGCG AAACAAGCTC 3120 3121 TACGTCACCT TTGTTGGAGA GGAGGGCCTG GACTACAGTG GCCCCTCGCG GGAGTTCTTC 3180 3181 TTCCTTCTGT CTCAGGAGCT CTTCAACCCT TATTATGGAC TCTTTGAGTA CTCGGCAAAT 3240 3241 GATACTTACA CGGTGCAGAT CAGCCCCATG TCCGCATTTG TAGAAAACCA TCTTGAGTGG 3300 3301 TTCAGGTTTA GCGGTCGCAT CCTGGGCCTG GCTCTGATCC ATCAGTACCT TCTTGATGCT 3360 3361 TTCTTCACGA GGCCCTTCTA CAAGGCACTC CTGAGACTGC CCTGTGATTT GAGTGACCTG 3420 3421 GAATATTTGG ATGAGGAATT CCACCAGAGT TTGCAGTGGA TGAAGGACAA CAACATCACA 3480 3481 GACATCTTAG ACCTCACTTT CACTGTTAAT GAAGAGGTTT TTGGACAGGT CACGGAAAGG 3540 3541 GAGTTGAAGT CTGGAGGAGC CAACACACAG GTGACGGAGA AGAACAAGAA GGAGTACATC 3600 3601 GAGCGCATGG TGAAGTGGCG GGTGGAGCGC GGCGTGGTAC AGCAAACCGA GGCGCTGGTG 3660 3661 CGCGGCTTCT ACGAGGTTGT AGACTCGAGG CTGGTGTCCG TGTTTGATGC CAGGGAGCTG 3720 3721 GAGCTGGTGA TAGCTGGCAC CGCGGAAATC GACCTAAATG ACTGGCGGAA TAACACCGAG 3780 3781 TACCGGGGAG GTTACCACGA TGGGCATCTC GTGATCCGCT GGTTCTGGGC TGCGGTGGAG 3840 3841 CGCTTCAATA ATGAGCAGAG GCTGAGATTA CTGCAGTTTG TCACGGGAAC ATCCAGCGTG 3900 3901 CCCTATGAAG GCTTCGCAGC CCTCCGTGGG AGCAATGGGC TTCGGCGCTT CTGCATAGAG 3960 3961 AAATGGGGGA AAATTACTTC TCTCCCCAGG GCACACACAT GCTTCAACCG ACTGGATCTT 4020 4021 CCACCGTATC CCTCGTACTC CATGTTGTAT GAAAAGCTGT TAACAGCAGT AGAGGAAACC 4080 4081 AGCACCTTTG GACTTGAGTG A 4101 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a003 | Homo sapiens | 0.0 | 3139 | undefined |
| LLPS-Mum-a004 | Mus musculus | 0.0 | 2740 | undefined |