LLPS-Gaga-a918
APOOL
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | MICOS complex subunit MIC27; Apolipoprotein O-like; Protein FAM121A |
| Gene Name: | APOOL, FAM121A, MIC27, RCJMB04_13b18 |
| Ensembl Gene: | ENSGALG00000016345.6 |
| Ensembl Protein: | ENSGALP00000026316.6 |
| Organism: | Gallus gallus |
| Taxa ID: | 9031 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSGALT00000026366.6 | ENSGALP00000026316.6 |
| Ensembl | ENSGALT00000087005.2 | ENSGALP00000063958.1 |
| Ensembl | ENSGALT00000087393.2 | ENSGALP00000063301.1 |
| UniProt | Q5ZK55, MIC27_CHICK | |
| GeneBank | AJ720229 | CAG31888.1 |
| RefSeq | NM_001006434.2 | NP_001006434.1 |
| Entrez | 418598 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MLKVIRLGAT PVSLSLLSIQ VYAASSEKET SKKELLKIDE LSLYSSPARE TKYVENPQTQ 60 61 LEEGVSQLRH AMEPYTAWCQ DLYAKAMPKL EKAVEHGREG CEFLQNPPAG FYPRLGVIGF 120 121 AGILGLFLAR GSKIKKLVYP AGFMSIGASM YYPQQAVAIA KVAGTQLYDW SLQGYIAVES 180 181 LWKDNPKKKK SGKKGDKGEV EGDKPLEIHA ASNEEKALK 219 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCAGGGG ACGTGGAAGG GTTTAGCTCC TCCATCCATG ACACCAGTGT CTCTGCTGGA 60 61 TTCAGAGCAC TGTATGAGGA GGGATTGCTT CTTGATGTCA CACTTGTCAT TGAAGACCAC 120 121 CAATTTCAGG CCCATAAAGC ACTGCTTGCC ACCCAGAGTG ATTACTTCAG GATTATGTTC 180 181 ACAGCTGACA TGCGAGAACG AGATCAGGAC AAAATCCATT TGAAAGGTCT GACAGCTACA 240 241 GGCTTCAGTC ATGTCCTCCA ATTCATGTAT TATGGAACTA TTGAACTGAG TATGAACACT 300 301 GTTCATGAAA TCCTTCAGGC TGCCATGTAC GTCCAGCTTA TAGAGGTGGT AAAGTTTTGC 360 361 TGCTCTTTTC TCTTAGCTAA AATCTGCCTA GAAAACTGTG CGGAAATTAT GAGACTTCTG 420 421 GATGATTTTG GTGTAAACAT CGAAGGAGTC AGGGAAAAAT TGGACTCTTT CCTGCTAGAG 480 481 AATTTTGTGC CGCTCATGTC CAGACCTGAT TTCCTTTCGT ATCTGAGCTT TGAAAAGCTC 540 541 ATGTCTTACT TGGATAATGA TCATCTGAGC AGGTTTCCAG AGATAGAGCT GTATGAAGCT 600 601 GTTCAGGCCT GGCTGCGCCA TGATAGAAGA CGCTGGAGGC ATACGGACAC CATCATTCAG 660 661 AACATCAGGT TTTGTTTGAT GACACCATCC AGTGTTTTTG AGAAGGTAAA AACATCAGAG 720 721 TTTTACCGAT ACTCCCGGCA GCTGCGACAT GAGGTTGACC AAGCCATGAA TTACTTTCAT 780 781 AGCGTTCACC AGCAGCCTTT GATGGAAATG AAATCGAACA AAATTCGTTC TGCCAAACCC 840 841 CAGACTGCCG TGTTTAGAGG AATGATAGGA CACAGTATGG TAAACAGTAA AATTCTTCTC 900 901 TTGCACAAAC CGAGGGTCTG GTGGGAACTA GAGGGTCCTC AAGTACCTTT ACGACCAGAC 960 961 TGCCTTGCCA TTGTGAATAA CTTTGTGTTC CTGTTAGGTG GGGAAGAACT GGGGCCAGAC 1020 1021 GGTGAGTTTC ATGCTTCATC CAAAGTGTTT AGATATGACC CAAGACAGAA CACTTGGTTA 1080 1081 CGAATGGCAG ACATGTCTGT CCCGCGTTCT GAGTTTGCTG TTGGAGTTAT TGGGAGGTAC 1140 1141 GTTTATGCAG TGGCTGGGAG AACCAGGGAT GAAACCTTTT ATTCAACTGA ACGGTATGAT 1200 1201 ATCACTGAAG ATAAATGGGA ATTTGTAGAT CCCTATCCAG TCAATAAATA CGGACATGAA 1260 1261 GGAACTGTGC TGGGTAACAA GTTGTATATC ACTGGTGGAA TTACATCGTC TTCAACTTCT 1320 1321 AAGCAAGTGT GCGTATTCGA TCCCAGTAAA GAGGGGACAG TAGAGCAGCG AACAAGGAGA 1380 1381 ACTCAAGTGG CCACTAACTG TTGGGAGAAC AAATGCAAAA TGAATTATGC AAGATGCTTT 1440 1441 CACAAAATGA TTTCTTATAA TGCCTGA 1467 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | MICOS complex | |
Cellular Component | Mitochondrion | |
Biological Process | Cristae formation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mum-a1031 | Mus musculus | 3e-73 | 230 | undefined |
| LLPS-Hos-a1046 | Homo sapiens | 5e-75 | 234 | undefined |