• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gaga-0609
MDH1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Malate dehydrogenase, cytoplasmic; Cytosolic malate dehydrogenase
Gene Name: MDH1, RCJMB04_2g5
Ensembl Gene: ENSGALG00000008858.7
Ensembl Protein: ENSGALP00000051015.2
Organism: Gallus gallus
Taxa ID: 9031
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGATRGLART  PLPLQRHLAT  SEAPLPAHAQ  QPRGARCPPP  SFLSGRRRLL  PSRACARLAA  60
61    LEFNARPDRP  LSDACANRKA  NAVLTFIFQE  RVRSARSRSS  SPSGSREADG  CNESARGAGR  120
121   RDNGANSVRG  RGVRAPGHSG  TCSSAAATTT  QGGATRDYSS  HAAARCGAPR  PSAVPQRNAA  180
181   GGRSRAVEVT  SRLLLGPLLP  AMGEPIRVLV  TGAAGQIAYS  LLYSIAKGDV  FGKEQPLVLV  240
241   LLDITPMMTV  LEGVVMELQD  CALPLLREVI  PTDKEEVAFK  DLDIAILVGS  MPRREGMERK  300
301   DLLKANVKIF  KSQGAALDKY  AKKTVKVVVV  GNPANTNCLI  ASKSAPSIPK  ENFSCLTRLD  360
361   HNRAKSQIAL  KLGVTSNDVK  NVIIWGNHSS  TQYPDVNHAK  VNVKGKEVGV  YEAIKDDSWL  420
421   KGDFILTVQQ  RGAAVIKARK  LSSAMSAAKA  ICDHVRDIWF  GTPAGEFVSM  GVISDGNSYG  480
481   VPEDLLYSFP  VVIKDKTWKF  VEGLPINDFS  REKMDLTAKE  LTEEKETAVE  FLSSA  535
Nucleotide CDS Sequence (FASTA)
1     ATGGGCGCAA  CCCGGGGTCT  TGCGCGCACG  CCGCTCCCGC  TGCAGCGTCA  CCTAGCAACC  60
61    AGCGAAGCAC  CGCTACCTGC  GCACGCGCAG  CAGCCACGCG  GCGCGCGATG  TCCTCCTCCT  120
121   TCCTTCCTCT  CCGGACGGCG  CCGACTCCTC  CCCTCGCGCG  CATGCGCACG  GCTGGCTGCT  180
181   CTTGAGTTCA  ACGCGCGCCC  CGACCGCCCT  CTGTCTGACG  CATGCGCAAA  CCGAAAAGCC  240
241   AACGCCGTTT  TAACCTTCAT  CTTTCAGGAG  CGCGTGCGCA  GCGCTCGGAG  CCGCTCATCG  300
301   TCCCCTAGCG  GCTCTCGGGA  GGCGGACGGT  TGCAATGAAT  CGGCCAGAGG  GGCGGGGCGT  360
361   CGGGACAACG  GCGCCAATAG  CGTGCGGGGG  CGCGGCGTGC  GTGCCCCGGG  GCACTCTGGG  420
421   ACCTGTAGTT  CGGCCGCCGC  CACAACAACG  CAGGGCGGCG  CGACTCGCGA  CTACAGTTCC  480
481   CATGCAGCTG  CGCGCTGCGG  CGCGCCCCGC  CCCTCCGCGG  TGCCTCAGCG  CAACGCCGCC  540
541   GGCGGTCGCA  GTCGCGCCGT  AGAGGTGACC  TCGAGGCTGC  TGCTCGGCCC  GCTGCTCCCA  600
601   GCCATGGGTG  AACCCATCAG  AGTCCTGGTG  ACCGGAGCTG  CCGGGCAAAT  TGCTTACTCC  660
661   CTGCTCTACA  GCATCGCCAA  GGGAGATGTC  TTTGGCAAAG  AGCAGCCTCT  TGTGCTTGTG  720
721   CTGCTGGATA  TCACCCCTAT  GATGACTGTT  TTGGAAGGCG  TAGTGATGGA  GCTGCAAGAC  780
781   TGTGCCCTGC  CACTGCTGAG  AGAGGTCATT  CCAACAGACA  AGGAGGAAGT  TGCATTCAAA  840
841   GACCTTGACA  TAGCAATTCT  GGTTGGCTCC  ATGCCGAGGA  GAGAAGGCAT  GGAGAGGAAG  900
901   GATTTGCTCA  AAGCAAATGT  GAAAATTTTC  AAGTCTCAGG  GTGCAGCTTT  GGACAAATAT  960
961   GCCAAAAAGA  CTGTGAAGGT  GGTAGTAGTT  GGGAATCCAG  CAAATACTAA  CTGTTTGATT  1020
1021  GCATCAAAGT  CAGCCCCATC  AATACCAAAG  GAAAACTTCA  GCTGCTTGAC  TCGCTTGGAT  1080
1081  CACAACAGAG  CTAAATCTCA  GATTGCTCTG  AAGCTTGGTG  TGACTTCTAA  CGATGTGAAG  1140
1141  AATGTCATCA  TTTGGGGCAA  CCACTCCTCC  ACTCAGTATC  CAGATGTTAA  CCATGCAAAG  1200
1201  GTGAATGTGA  AAGGAAAGGA  AGTCGGAGTT  TATGAAGCTA  TAAAAGATGA  CAGCTGGCTG  1260
1261  AAGGGAGACT  TTATCCTGAC  TGTTCAGCAA  CGTGGAGCAG  CTGTTATTAA  GGCTAGGAAG  1320
1321  CTGTCCAGTG  CGATGTCAGC  TGCCAAAGCT  ATCTGTGATC  ATGTGAGAGA  CATCTGGTTT  1380
1381  GGCACTCCAG  CGGGAGAATT  TGTTTCCATG  GGAGTCATTT  CTGATGGCAA  TTCTTACGGC  1440
1441  GTTCCTGAAG  ACCTGCTATA  TTCATTCCCT  GTTGTGATCA  AGGACAAGAC  CTGGAAGTTT  1500
1501  GTTGAGGGTC  TTCCTATTAA  TGACTTTTCT  CGTGAGAAGA  TGGATCTGAC  TGCTAAGGAG  1560
1561  TTAACCGAAG  AGAAGGAGAC  AGCTGTGGAA  TTCCTCTCCA  GTGCATGA  1608

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Meg-2923Meleagris gallopavo100.00.0 635
LLPS-Anp-0106Anas platyrhynchos99.70.0 634
LLPS-Fia-3017Ficedula albicollis98.20.0 632
LLPS-Cea-3342Cercocebus atys92.911e-166 480
LLPS-Ora-2975Ornithorhynchus anatinus92.220.0 602
LLPS-Pes-2237Pelodiscus sinensis91.920.0 597
LLPS-Sah-2734Sarcophilus harrisii91.320.0 595
LLPS-Anc-2906Anolis carolinensis91.320.0 588
LLPS-Mal-2280Mandrillus leucophaeus91.270.0 590
LLPS-Paa-3993Papio anubis91.270.0 589
LLPS-Maf-3783Macaca fascicularis91.270.0 590
LLPS-Man-1053Macaca nemestrina91.270.0 591
LLPS-Mod-2924Monodelphis domestica91.240.0 588
LLPS-Aon-1581Aotus nancymaae90.960.0 589
LLPS-Nol-1611Nomascus leucogenys90.960.0 590
LLPS-Pat-4359Pan troglodytes90.960.0 590
LLPS-Pap-4223Pan paniscus90.850.0 583
LLPS-Chs-3026Chlorocebus sabaeus90.720.0 594
LLPS-Poa-1224Pongo abelii90.720.0 593
LLPS-Gog-0564Gorilla gorilla90.660.0 590
LLPS-Hos-3373Homo sapiens90.660.0 588
LLPS-Ran-2915Rattus norvegicus90.120.0 587
LLPS-Caj-4110Callithrix jacchus90.120.0 588
LLPS-Orc-3918Oryctolagus cuniculus90.120.0 588
LLPS-Fud-3111Fukomys damarensis89.820.0 590
LLPS-Cap-3928Cavia porcellus89.820.0 588
LLPS-Mam-3193Macaca mulatta89.610.0 588
LLPS-Mum-3564Mus musculus89.520.0 586
LLPS-Rhb-1541Rhinopithecus bieti89.460.0 573
LLPS-Sus-3527Sus scrofa89.220.0 584
LLPS-Ova-3459Ovis aries89.160.0 581
LLPS-Otg-1006Otolemur garnettii89.160.0 582
LLPS-Bot-1537Bos taurus88.920.0 584
LLPS-Eqc-4685Equus caballus88.920.0 583
LLPS-Myl-0953Myotis lucifugus88.860.0 579
LLPS-Mea-2907Mesocricetus auratus88.860.0 580
LLPS-Dio-4119Dipodomys ordii88.620.0 575
LLPS-Tut-1927Tursiops truncatus88.550.0 573
LLPS-Cas-1716Carlito syrichta88.550.0 573
LLPS-Ict-4545Ictidomys tridecemlineatus88.320.0 583
LLPS-Aim-2384Ailuropoda melanoleuca87.950.0 572
LLPS-Mup-1879Mustela putorius furo87.720.0 575
LLPS-Urm-3514Ursus maritimus87.720.0 575
LLPS-Caf-2799Canis familiaris87.650.0 568
LLPS-Fec-4070Felis catus87.130.0 567
LLPS-Lac-3514Latimeria chalumnae87.130.0 563
LLPS-Loa-2913Loxodonta africana87.050.0 562
LLPS-Leo-1013Lepisosteus oculatus85.710.0 555
LLPS-Asm-3627Astyanax mexicanus83.730.0 546
LLPS-Ten-3370Tetraodon nigroviridis82.530.0 546
LLPS-Scm-3983Scophthalmus maximus82.480.0 538
LLPS-Icp-3428Ictalurus punctatus82.440.0 549
LLPS-Orn-2752Oreochromis niloticus82.230.0 543
LLPS-Scf-3005Scleropages formosus81.520.0 537
LLPS-Dar-3425Danio rerio81.140.0 535
LLPS-Gaa-4015Gasterosteus aculeatus80.850.0 532
LLPS-Pof-3720Poecilia formosa80.720.0 533
LLPS-Orl-1482Oryzias latipes78.550.0 537
LLPS-Tar-2630Takifugu rubripes78.312e-178 513
LLPS-Xim-2030Xiphophorus maculatus78.260.0 535
LLPS-Drm-1019Drosophila melanogaster68.373e-135 403
LLPS-Cae-1444Caenorhabditis elegans63.064e-123 372
LLPS-Met-1229Medicago truncatula60.584e-118 359
LLPS-Arl-0504Arabidopsis lyrata60.262e-118 360
LLPS-Sem-2245Selaginella moellendorffii60.268e-114 348
LLPS-Art-1156Arabidopsis thaliana60.262e-118 360
LLPS-Cus-1089Cucumis sativus60.064e-116 354
LLPS-Glm-1074Glycine max59.942e-115 352
LLPS-Brn-3007Brassica napus59.622e-116 354
LLPS-Mae-1764Manihot esculenta59.623e-116 354
LLPS-Prp-2029Prunus persica59.295e-113 347
LLPS-Brr-0198Brassica rapa59.296e-116 353
LLPS-Bro-2948Brassica oleracea58.973e-116 354
LLPS-Gor-2699Gossypium raimondii58.792e-112 344
LLPS-Tra-1920Triticum aestivum58.735e-115 351
LLPS-Sot-2284Solanum tuberosum58.651e-115 352
LLPS-Mua-0830Musa acuminata58.659e-114 348
LLPS-Nia-1685Nicotiana attenuata58.653e-115 352
LLPS-Zem-2094Zea mays58.424e-110 338
LLPS-Hea-0474Helianthus annuus58.366e-117 358
LLPS-Dac-2163Daucus carota58.042e-99 310
LLPS-Orni-1088Oryza nivara57.752e-111 342
LLPS-Sol-1530Solanum lycopersicum57.685e-114 348
LLPS-Php-2047Physcomitrella patens57.376e-111 340
LLPS-Orb-1627Oryza barthii57.142e-110 340
LLPS-Orr-2373Oryza rufipogon57.142e-110 340
LLPS-Ors-0607Oryza sativa57.142e-110 340
LLPS-Brd-2071Brachypodium distachyon56.734e-110 339
LLPS-Lep-0777Leersia perrieri56.731e-109 338
LLPS-Orm-1808Oryza meridionalis56.538e-109 335
LLPS-Orp-0091Oryza punctata56.237e-109 336
LLPS-Orbr-1696Oryza brachyantha56.091e-108 335
LLPS-Sei-2292Setaria italica55.221e-106 330
LLPS-Sob-2072Sorghum bicolor54.986e-109 336
LLPS-Orgl-0369Oryza glumaepatula50.49e-101 317
LLPS-Vir-0288Vigna radiata50.05e-76 252
LLPS-Coc-2028Corchorus capsularis47.715e-77 256
LLPS-Via-1645Vigna angularis47.596e-78 258
LLPS-Ori-1844Oryza indica47.427e-79 261
LLPS-Viv-0001Vitis vinifera47.395e-75 251
LLPS-Phv-1826Phaseolus vulgaris47.271e-77 258
LLPS-Hov-1051Hordeum vulgare47.216e-78 258
LLPS-Pot-0384Populus trichocarpa46.733e-74 249
LLPS-Chc-1233Chondrus crispus46.32e-70 236
LLPS-Thc-0325Theobroma cacao46.083e-73 246
LLPS-Tru-0620Triticum urartu45.427e-61 211
LLPS-Org-0858Oryza glaberrima32.329e-0755.1
LLPS-Tag-1974Taeniopygia guttata27.965e-31 129
LLPS-Amt-2136Amborella trichopoda27.684e-0963.2
LLPS-Cis-1122Ciona savignyi26.366e-26 114