DrLLPS - Data resource of LLPS

LLPS-Fuv-1287
FVEG_06148

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Acyl-CoA desaturase
Gene Name:	FVEG_06148
Ensembl Gene:	FVEG_06148
Ensembl Protein:	FVEG_06148T0
Organism:	Fusarium verticillioides
Taxa ID:	334819
LLPS Type:	LLPS regulator

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0745	O00767	Regulator	Stress granule	38.35	2e-55	194

▼ FUNCTION

Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	FVEG_06148T0	FVEG_06148T0
UniProt		W7M162, W7M162_GIBM7
GeneBank	DS022248	EWG45323.1
RefSeq	XM_018894431.1	XP_018751514.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MATATAAGKN AQPFPDGTKD YVPLRAGGAK KDINKVHIAD TPMTWSNWPQ HINWLNTTLV 60 61 IFVPLAGFIS AYWVPLQLKT ALWAVFYYVH TGLGITAGYH RLWSHSAYKG TTPLKIYLAA 120 121 VGAGAVQGSI RWWSYGHRVH HRYTDTDKDP YSVRKGLMYS HMGWMILKQN PKRQGRTDIT 180 181 DLNEDAVVVW QHKNYIKCVL FMALAFPALV AGLGWGDWWG GLVYAGILRV CFVQQATFCV 240 241 NSLAHWLGDQ PFDDRNSPRD HVITALVTLG EGYHNFHHEF PSDYRNAIEW WQYDPTKWSI 300 301 WCWKQLGLAY ELKEFRANEI EKGRVQQLQK KLDQKRATLD WGIPLEQLPV VDWDDFVAQA 360 361 KAGKGLVAIA GVIHDVTDFI KDHPGGKALI NSAIGKDATA IFNGGVYLHS NAAHNLLSTM 420 421 RVGVLRGGCE VEIWKRAQFE NKDITYMNDS AGQRIIRAGS QVTKIVQPAA SADAA 475

Protein Sequence (FASTA)

1     MATATAAGKN  AQPFPDGTKD  YVPLRAGGAK  KDINKVHIAD  TPMTWSNWPQ  HINWLNTTLV  60
61    IFVPLAGFIS  AYWVPLQLKT  ALWAVFYYVH  TGLGITAGYH  RLWSHSAYKG  TTPLKIYLAA  120
121   VGAGAVQGSI  RWWSYGHRVH  HRYTDTDKDP  YSVRKGLMYS  HMGWMILKQN  PKRQGRTDIT  180
181   DLNEDAVVVW  QHKNYIKCVL  FMALAFPALV  AGLGWGDWWG  GLVYAGILRV  CFVQQATFCV  240
241   NSLAHWLGDQ  PFDDRNSPRD  HVITALVTLG  EGYHNFHHEF  PSDYRNAIEW  WQYDPTKWSI  300
301   WCWKQLGLAY  ELKEFRANEI  EKGRVQQLQK  KLDQKRATLD  WGIPLEQLPV  VDWDDFVAQA  360
361   KAGKGLVAIA  GVIHDVTDFI  KDHPGGKALI  NSAIGKDATA  IFNGGVYLHS  NAAHNLLSTM  420
421   RVGVLRGGCE  VEIWKRAQFE  NKDITYMNDS  AGQRIIRAGS  QVTKIVQPAA  SADAA  475

▼ KEYWORD

ID	Family
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-0249	Electron transport
KW-0275	Fatty acid biosynthesis
KW-0276	Fatty acid metabolism
KW-0349	Heme
KW-0408	Iron
KW-0444	Lipid biosynthesis
KW-0443	Lipid metabolism
KW-0472	Membrane
KW-0479	Metal-binding
KW-0560	Oxidoreductase
KW-1185	Reference proteome
KW-0812	Transmembrane
KW-1133	Transmembrane helix
KW-0813	Transport

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0016021	Cellular Component	Integral component of membrane
GO:0020037	Molecular Function	Heme binding
GO:0046872	Molecular Function	Metal ion binding
GO:0004768	Molecular Function	Stearoyl-CoA 9-desaturase activity
GO:0006636	Biological Process	Unsaturated fatty acid biosynthetic process

▼ KEGG

fvr:FVEG_06148

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Fuo-0831	Fusarium oxysporum	99.79	0.0	947
LLPS-Fus-1437	Fusarium solani	90.74	0.0	879
LLPS-Trr-0428	Trichoderma reesei	82.68	0.0	800
LLPS-Beb-0846	Beauveria bassiana	82.25	0.0	762
LLPS-Ast-1573	Aspergillus terreus	79.41	0.0	713
LLPS-Asn-0314	Aspergillus nidulans	78.83	0.0	711
LLPS-Asc-1400	Aspergillus clavatus	78.83	0.0	715
LLPS-Nef-1564	Neosartorya fischeri	78.83	0.0	712
LLPS-Asfu-0715	Aspergillus fumigatus	78.83	0.0	708
LLPS-Gag-0452	Gaeumannomyces graminis	78.06	0.0	746
LLPS-Ved-1127	Verticillium dahliae	77.89	0.0	761
LLPS-Phn-1280	Phaeosphaeria nodorum	76.29	0.0	702
LLPS-Tum-1332	Tuber melanosporum	75.0	0.0	658
LLPS-Zyt-1125	Zymoseptoria tritici	74.1	0.0	660
LLPS-Asf-1067	Aspergillus flavus	73.86	0.0	684
LLPS-Aso-0130	Aspergillus oryzae	73.86	0.0	684
LLPS-Dos-0580	Dothistroma septosporum	72.85	0.0	662
LLPS-Asni-0718	Aspergillus niger	69.02	0.0	581
LLPS-Pytr-0299	Pyrenophora triticirepentis	68.83	0.0	618
LLPS-Lem-0474	Leptosphaeria maculans	66.04	0.0	564
LLPS-Scj-1086	Schizosaccharomyces japonicus	58.68	4e-177	513
LLPS-Asg-0518	Ashbya gossypii	57.87	3e-152	449
LLPS-Scp-1343	Schizosaccharomyces pombe	57.14	1e-169	494
LLPS-Scc-0955	Schizosaccharomyces cryophilus	56.62	3e-162	475
LLPS-Kop-1275	Komagataella pastoris	56.54	4e-166	486
LLPS-Pug-1119	Puccinia graminis	56.53	5e-146	434
LLPS-Put-1039	Puccinia triticina	56.53	1e-145	434
LLPS-Crn-1127	Cryptococcus neoformans	55.04	3e-147	441
LLPS-Sac-1292	Saccharomyces cerevisiae	54.82	2e-148	441
LLPS-Mel-1194	Melampsora laricipopulina	54.77	3e-147	438
LLPS-Abg-0979	Absidia glauca	52.66	2e-141	421
LLPS-Miv-0767	Microbotryum violaceum	50.12	2e-139	419
LLPS-Cae-0334	Caenorhabditis elegans	40.17	4e-55	193
LLPS-Bot-1918	Bos taurus	40.14	9e-56	195
LLPS-Caj-0372	Callithrix jacchus	40.07	4e-53	187
LLPS-Cis-0232	Ciona savignyi	40.0	2e-59	203
LLPS-Eqc-0676	Equus caballus	39.79	3e-55	193
LLPS-Mod-3899	Monodelphis domestica	39.71	2e-55	194
LLPS-Pes-1081	Pelodiscus sinensis	39.67	1e-48	174
LLPS-Gaga-3324	Gallus gallus	39.63	1e-54	191
LLPS-Sus-3673	Sus scrofa	39.57	5e-41	155
LLPS-Maf-1759	Macaca fascicularis	39.08	3e-54	191
LLPS-Cea-4430	Cercocebus atys	39.08	3e-54	191
LLPS-Sah-4038	Sarcophilus harrisii	38.83	3e-55	194
LLPS-Paa-1978	Papio anubis	38.73	1e-53	189
LLPS-Loa-0366	Loxodonta africana	38.72	4e-55	194
LLPS-Tag-3300	Taeniopygia guttata	38.43	2e-52	185
LLPS-Gog-0399	Gorilla gorilla	38.35	6e-53	188
LLPS-Chs-4176	Chlorocebus sabaeus	38.35	7e-54	191
LLPS-Ora-1581	Ornithorhynchus anatinus	38.35	1e-53	189
LLPS-Mal-2212	Mandrillus leucophaeus	38.35	8e-54	190
LLPS-Hos-0745	Homo sapiens	38.35	6e-53	188
LLPS-Pap-4475	Pan paniscus	38.35	5e-53	188
LLPS-Pat-2730	Pan troglodytes	38.35	5e-53	188
LLPS-Ict-0404	Ictidomys tridecemlineatus	38.35	3e-52	186
LLPS-Poa-2153	Pongo abelii	38.35	5e-53	188
LLPS-Mam-4458	Macaca mulatta	38.35	8e-54	190
LLPS-Rhb-4670	Rhinopithecus bieti	38.3	6e-53	187
LLPS-Mup-4348	Mustela putorius furo	38.16	7e-48	174
LLPS-Orn-3829	Oreochromis niloticus	38.1	1e-43	162
LLPS-Caf-1029	Canis familiaris	38.08	5e-55	192
LLPS-Fec-1344	Felis catus	37.71	3e-47	173
LLPS-Aon-3620	Aotus nancymaae	37.59	1e-54	193
LLPS-Ova-4197	Ovis aries	37.59	2e-53	189
LLPS-Myl-4124	Myotis lucifugus	37.59	6e-55	194
LLPS-Orc-0652	Oryctolagus cuniculus	37.59	4e-53	189
LLPS-Nol-1048	Nomascus leucogenys	37.59	2e-52	187
LLPS-Fud-1090	Fukomys damarensis	37.22	8e-52	185
LLPS-Mea-3369	Mesocricetus auratus	37.22	4e-50	180
LLPS-Aim-3206	Ailuropoda melanoleuca	36.84	1e-53	190
LLPS-Otg-3241	Otolemur garnettii	36.84	1e-51	184
LLPS-Cap-2547	Cavia porcellus	36.84	1e-51	184
LLPS-Tut-0419	Tursiops truncatus	36.59	6e-55	192
LLPS-Dio-0553	Dipodomys ordii	36.47	5e-50	180
LLPS-Urm-1997	Ursus maritimus	36.47	2e-52	187
LLPS-Cii-0827	Ciona intestinalis	36.39	2e-54	190
LLPS-Anc-3374	Anolis carolinensis	36.36	4e-50	181
LLPS-Icp-3141	Ictalurus punctatus	36.16	4e-48	174
LLPS-Mum-3711	Mus musculus	36.09	1e-50	182
LLPS-Anp-3354	Anas platyrhynchos	35.79	3e-51	184
LLPS-Asm-0021	Astyanax mexicanus	35.56	1e-49	179
LLPS-Man-0913	Macaca nemestrina	35.47	3e-42	159
LLPS-Fia-2064	Ficedula albicollis	35.42	1e-51	185
LLPS-Ten-3488	Tetraodon nigroviridis	35.4	9e-47	171
LLPS-Ran-0093	Rattus norvegicus	35.34	1e-49	179
LLPS-Orl-0420	Oryzias latipes	35.21	6e-46	169
LLPS-Scf-3550	Scleropages formosus	35.21	4e-50	180
LLPS-Meg-1985	Meleagris gallopavo	35.06	6e-52	185
LLPS-Pof-2373	Poecilia formosa	34.86	1e-48	176
LLPS-Drm-1630	Drosophila melanogaster	34.66	2e-45	167
LLPS-Gaa-3343	Gasterosteus aculeatus	34.51	7e-48	174
LLPS-Sem-1598	Selaginella moellendorffii	34.35	1e-27	116
LLPS-Tar-0630	Takifugu rubripes	33.8	1e-48	176
LLPS-Xim-2150	Xiphophorus maculatus	33.8	2e-47	172
LLPS-Leo-2413	Lepisosteus oculatus	33.45	2e-41	162
LLPS-Prp-0984	Prunus persica	32.96	3e-30	123
LLPS-Nia-1389	Nicotiana attenuata	32.77	1e-26	114
LLPS-Brn-0967	Brassica napus	32.37	5e-24	107
LLPS-Met-2483	Medicago truncatula	32.2	6e-29	121
LLPS-Via-2169	Vigna angularis	32.12	2e-28	119
LLPS-Osl-0179	Ostreococcus lucimarinus	31.87	2e-27	117
LLPS-Bro-1879	Brassica oleracea	31.82	2e-24	108
LLPS-Gor-1714	Gossypium raimondii	31.62	1e-25	112
LLPS-Sol-0875	Solanum lycopersicum	31.49	1e-24	108
LLPS-Sot-1992	Solanum tuberosum	31.49	2e-25	110
LLPS-Glm-0153	Glycine max	31.44	5e-28	118
LLPS-Hea-1958	Helianthus annuus	31.4	1e-25	111
LLPS-Chr-0280	Chlamydomonas reinhardtii	30.52	9e-26	112
LLPS-Gas-1299	Galdieria sulphuraria	29.96	5e-29	120
LLPS-Art-3041	Arabidopsis thaliana	29.52	1e-23	105
LLPS-Arl-2280	Arabidopsis lyrata	29.02	4e-24	106
LLPS-Cym-1099	Cyanidioschyzon merolae	28.8	3e-31	128
LLPS-Cus-1622	Cucumis sativus	28.28	6e-26	111
LLPS-Pot-2530	Populus trichocarpa	28.26	8e-25	109
LLPS-Mae-2507	Manihot esculenta	26.8	5e-25	109

LLPS-Fuv-1287FVEG_06148

Protein Sequence

Nucleotide Sequence

LLPS-Fuv-1287
FVEG_06148