• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Fud-3150
H920_03584

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Thyroid hormone receptor alpha
Gene Name: H920_03584
Ensembl Gene: ENSFDAG00000014894.1
Ensembl Protein: ENSFDAP00000006025.1
Organism: Fukomys damarensis
Taxa ID: 885580
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, PML nuclear body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEQKPSKVEC  GSDPEENSAR  SPDGKRKRKN  GQCSLKTSMS  GYIPSYLDKD  EQCVVCGDRA  60
61    TGYHYRCITC  EGCKGFFRRT  IQKNLHPTYS  CKYDSCCVID  KITRNQCQLC  RFKKCIGVGM  120
121   AMDLVLDDSK  RVAKRKLIEQ  NRERRRKEEM  IRSLQQRPEP  TPEEWDLIHV  ATEAHRSTNA  180
181   QGSHWKQRRK  FLPDDIGQSP  IVSMPDGDKV  DLEAFSEFTK  IITPAITRVV  DFAKKLPMFS  240
241   ELPCEDQIIL  LKGCCMEIMS  LRAAVRYDPD  SDTLTLSGEM  AVKREQLKNG  GLGVVSDAIF  300
301   ELGKSLSAFN  LDDTEVALLQ  AVLLMSTDRS  GLLCVDKIEK  SQEAYLLAFE  HYVNHRKHNI  360
361   PHFWPKLLMK  EREVQSSILY  KGAAAEGRPG  GSLGVHPEGQ  QLLGMHVVQG  PQVRQLEQQL  420
421   GEAGSLRGPV  LQHQSPKSPQ  QRLLEVLHRS  GILHSRTVCG  NEDSSETGSL  SSEEEEEEEQ  480
481   EEEQEEEEEQ  EKKKKKEEEE  EEDPGADLPG  TSASP  515
Nucleotide CDS Sequence (FASTA)
1     ATGGAACAGA  AGCCAAGCAA  AGTGGAGTGT  GGGTCGGACC  CGGAGGAGAA  CAGTGCCAGG  60
61    TCACCAGATG  GAAAGCGAAA  AAGAAAGAAC  GGCCAATGTT  CCCTGAAAAC  CAGCATGTCA  120
121   GGGTATATCC  CTAGTTACCT  GGACAAAGAC  GAGCAGTGTG  TCGTGTGTGG  GGACAGGGCC  180
181   ACCGGTTATC  ACTACCGTTG  TATCACCTGT  GAGGGCTGCA  AGGGCTTCTT  TCGCCGCACA  240
241   ATCCAGAAGA  ACCTCCATCC  CACCTATTCT  TGCAAATATG  ACAGCTGCTG  CGTCATCGAC  300
301   AAAATCACCC  GCAACCAGTG  CCAGCTGTGC  CGCTTCAAGA  AGTGCATCGG  CGTGGGCATG  360
361   GCCATGGACC  TGGTTCTTGA  TGACTCAAAG  CGCGTAGCCA  AGCGCAAGCT  GATCGAGCAG  420
421   AACCGGGAGC  GGCGGCGGAA  GGAGGAGATG  ATCCGGTCCC  TGCAGCAGCG  GCCGGAGCCC  480
481   ACTCCCGAGG  AGTGGGACCT  GATCCACGTG  GCCACGGAGG  CCCATCGCAG  CACCAATGCC  540
541   CAGGGCAGCC  ATTGGAAGCA  GAGGAGGAAA  TTCCTGCCGG  ATGACATTGG  CCAGTCGCCC  600
601   ATCGTCTCCA  TGCCGGACGG  AGACAAGGTG  GACCTCGAGG  CCTTCAGCGA  GTTTACCAAG  660
661   ATCATCACAC  CGGCCATCAC  CCGCGTGGTG  GACTTTGCCA  AAAAACTGCC  CATGTTCTCC  720
721   GAGCTGCCTT  GTGAAGACCA  GATCATCCTC  CTGAAGGGGT  GCTGCATGGA  GATCATGTCT  780
781   CTGCGGGCGG  CCGTGCGCTA  TGACCCTGAC  AGCGACACCC  TGACGCTGAG  CGGGGAGATG  840
841   GCTGTCAAGC  GGGAGCAGCT  CAAGAACGGC  GGCCTGGGCG  TGGTCTCTGA  CGCCATCTTT  900
901   GAACTGGGCA  AGTCACTCTC  TGCCTTTAAC  CTGGATGACA  CGGAAGTGGC  TCTCCTGCAG  960
961   GCTGTGCTGC  TAATGTCAAC  AGACCGCTCG  GGCCTGCTGT  GTGTGGACAA  GATCGAGAAG  1020
1021  AGTCAGGAGG  CGTACCTGCT  GGCGTTCGAG  CACTACGTCA  ACCACCGCAA  ACACAACATT  1080
1081  CCGCACTTCT  GGCCCAAGCT  GCTGATGAAG  GAAAGAGAAG  TGCAGAGTTC  GATTCTGTAC  1140
1141  AAGGGGGCAG  CGGCGGAAGG  CCGGCCGGGC  GGGTCACTGG  GCGTCCACCC  GGAAGGACAG  1200
1201  CAGCTTCTCG  GAATGCATGT  TGTTCAGGGT  CCGCAGGTCC  GGCAGCTTGA  GCAGCAGCTT  1260
1261  GGTGAAGCGG  GAAGTCTCCG  AGGGCCGGTT  CTTCAGCACC  AGAGCCCGAA  GAGCCCGCAG  1320
1321  CAGCGTCTCC  TGGAGGTGCT  CCACCGAAGC  GGGATCCTCC  ATTCCAGAAC  GGTCTGTGGA  1380
1381  AATGAGGACA  GCAGTGAGAC  AGGCTCCCTG  AGCTCCGAGG  AGGAGGAGGA  GGAGGAGCAG  1440
1441  GAGGAGGAGC  AGGAGGAGGA  GGAGGAGCAG  GAGAAGAAGA  AGAAGAAGGA  GGAGGAGGAG  1500
1501  GAGGAGGACC  CTGGTGCAGA  CCTGCCAGGC  ACATCAGCCT  CTCCCTGA  1548

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Otg-2333Otolemur garnettii99.190.0 770
LLPS-Orc-0325Oryctolagus cuniculus98.70.0 946
LLPS-Mea-2434Mesocricetus auratus98.520.0 967
LLPS-Dio-3717Dipodomys ordii98.490.0 950
LLPS-Mum-0117Mus musculus98.480.0 945
LLPS-Mup-0678Mustela putorius furo98.270.0 949
LLPS-Fec-0472Felis catus98.270.0 950
LLPS-Ran-1993Rattus norvegicus98.260.0 944
LLPS-Chs-1139Chlorocebus sabaeus98.260.0 945
LLPS-Hos-0464Homo sapiens98.260.0 945
LLPS-Mal-0187Mandrillus leucophaeus98.250.0 939
LLPS-Paa-2324Papio anubis98.250.0 939
LLPS-Gog-0734Gorilla gorilla98.250.0 938
LLPS-Maf-2427Macaca fascicularis98.250.0 939
LLPS-Cea-0356Cercocebus atys98.250.0 939
LLPS-Pap-3217Pan paniscus98.250.0 938
LLPS-Pat-0048Pan troglodytes98.250.0 938
LLPS-Aim-2987Ailuropoda melanoleuca98.090.0 964
LLPS-Ict-0671Ictidomys tridecemlineatus98.090.0 964
LLPS-Eqc-0414Equus caballus98.090.0 964
LLPS-Urm-0240Ursus maritimus98.090.0 963
LLPS-Caf-0734Canis familiaris98.060.0 949
LLPS-Loa-1051Loxodonta africana98.040.0 938
LLPS-Rhb-1566Rhinopithecus bieti98.030.0 938
LLPS-Sus-2853Sus scrofa97.880.0 963
LLPS-Bot-3394Bos taurus97.840.0 942
LLPS-Cas-2339Carlito syrichta97.840.0 944
LLPS-Aon-1890Aotus nancymaae97.820.0 937
LLPS-Cap-1413Cavia porcellus97.460.0 959
LLPS-Ova-1125Ovis aries97.170.0 915
LLPS-Man-2892Macaca nemestrina96.415e-176 509
LLPS-Caj-3972Callithrix jacchus95.760.0 937
LLPS-Nol-4553Nomascus leucogenys95.057e-138 408
LLPS-Myl-0004Myotis lucifugus93.621e-50 176
LLPS-Sah-1354Sarcophilus harrisii92.970.0 695
LLPS-Anc-1763Anolis carolinensis90.30.0 687
LLPS-Mam-3666Macaca mulatta88.70.0 828
LLPS-Lac-3807Latimeria chalumnae87.570.0 660
LLPS-Fia-2291Ficedula albicollis87.20.0 665
LLPS-Mod-0565Monodelphis domestica86.290.0 793
LLPS-Gaa-0014Gasterosteus aculeatus85.550.0 635
LLPS-Leo-1165Lepisosteus oculatus85.470.0 639
LLPS-Scf-1205Scleropages formosus85.230.0 642
LLPS-Gaga-0114Gallus gallus84.95e-105 328
LLPS-Xet-0402Xenopus tropicalis83.380.0 652
LLPS-Dar-0395Danio rerio82.890.0 648
LLPS-Orn-3710Oreochromis niloticus82.70.0 645
LLPS-Tag-2107Taeniopygia guttata82.420.0 567
LLPS-Meg-1645Meleagris gallopavo82.420.0 568
LLPS-Scm-0119Scophthalmus maximus82.260.0 640
LLPS-Poa-4135Pongo abelii82.120.0 561
LLPS-Orl-2517Oryzias latipes81.990.0 646
LLPS-Xim-0347Xiphophorus maculatus81.890.0 639
LLPS-Tut-2376Tursiops truncatus81.820.0 550
LLPS-Ora-3265Ornithorhynchus anatinus81.198e-112 341
LLPS-Pof-0241Poecilia formosa78.740.0 622
LLPS-Ten-0246Tetraodon nigroviridis78.250.0 545
LLPS-Tar-3868Takifugu rubripes77.650.0 543
LLPS-Asm-1601Astyanax mexicanus76.020.0 526
LLPS-Icp-3634Ictalurus punctatus74.790.0 537
LLPS-Pes-1684Pelodiscus sinensis73.440.0 541
LLPS-Cis-0179Ciona savignyi41.265e-86 283
LLPS-Cii-1392Ciona intestinalis39.143e-83 276
LLPS-Anp-1677Anas platyrhynchos31.22e-49 181
LLPS-Drm-2076Drosophila melanogaster30.854e-45 174