• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Fud-3018
H920_08990

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: NAD-dependent protein deacetylase
Gene Name: H920_08990
Ensembl Gene: ENSFDAG00000011389.1
Ensembl Protein: ENSFDAP00000001384.1
Organism: Fukomys damarensis
Taxa ID: 885580
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

NAD-dependent protein deacetylase.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDFLRNLFSQ  TLGLGSQKER  LLDELTLEGV  VRYMQSERCC  RVICLVGAGI  STSAGIPDFR  60
61    SPTTGLYANL  EKYHLPYPEA  IFEIGYFKKH  PEPFFALAKE  LYPGQFKPTV  CHYFIRLLKE  120
121   KGLLLRCYTQ  NIDTLERVAG  LEPEDLVEAH  GTFYTSHCTS  QLCRREYTLG  WMKEKLFSEV  180
181   TPKCEKCQSV  VKPDIIFFGE  NLPARFFSCL  QSDFRKVDLL  IIMGTSLQVQ  PFASLIGKAP  240
241   LSTPRLLINK  EKTGHMDPFL  GMMMGLGGGM  DFDSKKAYRD  VAWLGDCDQG  CLALADLLGW  300
301   KKELEDLVRK  EHASIDAQSG  PSTPNPTTAA  SPRTSPPPAK  AEAKTTEGEK  SQ  352
Nucleotide CDS Sequence (FASTA)
1     ATGGACTTCC  TGAGGAATCT  CTTCTCCCAG  ACCCTGGGCC  TGGGCTCCCA  GAAGGAGCGT  60
61    CTGCTGGATG  AGCTAACTCT  GGAAGGGGTG  GTCCGCTACA  TGCAGAGCGA  GCGCTGTTGC  120
121   AGGGTCATCT  GCTTGGTCGG  AGCTGGAATC  TCTACATCGG  CGGGCATCCC  TGACTTCCGT  180
181   TCTCCAACCA  CTGGCCTTTA  CGCCAACCTG  GAGAAGTACC  ATCTTCCCTA  CCCAGAGGCC  240
241   ATCTTTGAGA  TTGGCTATTT  CAAGAAACAT  CCGGAACCCT  TCTTTGCCCT  TGCCAAGGAA  300
301   CTGTATCCTG  GGCAGTTCAA  GCCGACCGTC  TGTCACTACT  TCATCCGCCT  GCTGAAGGAG  360
361   AAGGGGCTGC  TCCTGCGCTG  CTACACACAG  AACATTGACA  CCCTGGAGCG  CGTGGCCGGG  420
421   CTGGAGCCCG  AGGACCTGGT  GGAGGCCCAC  GGCACCTTCT  ACACATCACA  CTGCACCAGC  480
481   CAGCTCTGCC  GGCGCGAGTA  CACCCTGGGC  TGGATGAAAG  AGAAGCTCTT  CTCGGAGGTG  540
541   ACCCCCAAGT  GCGAGAAATG  TCAGAGTGTG  GTGAAGCCTG  ACATCATCTT  TTTTGGCGAG  600
601   AACCTCCCGG  CACGGTTCTT  CTCCTGCTTG  CAGTCAGACT  TCCGGAAGGT  GGACCTGCTC  660
661   ATCATCATGG  GCACCTCGCT  GCAGGTGCAG  CCCTTCGCCT  CTCTCATTGG  CAAGGCACCG  720
721   CTGTCCACCC  CGCGCCTGCT  TATCAACAAG  GAGAAGACTG  GCCATATGGA  CCCCTTCCTC  780
781   GGAATGATGA  TGGGCCTGGG  AGGAGGCATG  GACTTTGACT  CGAAGAAGGC  CTACAGGGAC  840
841   GTAGCCTGGC  TGGGTGACTG  TGACCAGGGA  TGCCTGGCCC  TCGCTGACCT  CCTTGGATGG  900
901   AAGAAAGAGC  TGGAGGACCT  GGTCAGGAAG  GAGCACGCCA  GCATAGATGC  CCAATCGGGG  960
961   CCCAGCACTC  CCAACCCCAC  CACTGCAGCT  TCCCCCAGGA  CGTCCCCACC  TCCTGCCAAG  1020
1021  GCGGAGGCCA  AGACCACAGA  GGGGGAGAAG  TCCCAGTGA  1059

▼ KEYWORD

ID
Family
Complete proteome
Hydrolase
Metal-binding
NAD
Reference proteome
Zinc

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
NAD+ binding
Molecular Function
NAD-dependent histone deacetylase activity
Molecular Function
Zinc ion binding

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sus-1792Sus scrofa92.330.0 607
LLPS-Cap-2916Cavia porcellus92.050.0 600
LLPS-Dio-1587Dipodomys ordii91.820.0 583
LLPS-Fec-2835Felis catus91.220.0 609
LLPS-Eqc-1659Equus caballus91.190.0 605
LLPS-Ran-2654Rattus norvegicus91.190.0 592
LLPS-Loa-0523Loxodonta africana90.650.0 602
LLPS-Ict-3110Ictidomys tridecemlineatus90.340.0 602
LLPS-Myl-0676Myotis lucifugus90.340.0 599
LLPS-Urm-0351Ursus maritimus90.164e-113 344
LLPS-Aim-0808Ailuropoda melanoleuca90.140.0 597
LLPS-Orc-1409Oryctolagus cuniculus90.060.0 602
LLPS-Caf-2053Canis familiaris90.00.0 532
LLPS-Caj-2406Callithrix jacchus89.620.0 570
LLPS-Aon-0302Aotus nancymaae89.310.0 570
LLPS-Otg-1341Otolemur garnettii89.030.0 579
LLPS-Cas-0352Carlito syrichta88.640.0 578
LLPS-Bot-1905Bos taurus88.390.0 602
LLPS-Mup-1437Mustela putorius furo87.850.0 599
LLPS-Poa-3600Pongo abelii87.780.0 585
LLPS-Mum-2012Mus musculus87.780.0 596
LLPS-Man-0487Macaca nemestrina87.50.0 585
LLPS-Pap-3213Pan paniscus87.50.0 585
LLPS-Mam-4002Macaca mulatta87.50.0 586
LLPS-Cea-1913Cercocebus atys87.50.0 585
LLPS-Chs-0438Chlorocebus sabaeus87.50.0 585
LLPS-Maf-0726Macaca fascicularis87.50.0 585
LLPS-Pat-3223Pan troglodytes87.220.0 583
LLPS-Hos-0599Homo sapiens87.220.0 583
LLPS-Gog-2407Gorilla gorilla87.220.0 583
LLPS-Ova-2291Ovis aries87.010.0 584
LLPS-Paa-0919Papio anubis84.380.0 550
LLPS-Mal-0192Mandrillus leucophaeus82.950.0 540
LLPS-Sah-1307Sarcophilus harrisii82.556e-130 378
LLPS-Nol-0838Nomascus leucogenys82.540.0 533
LLPS-Pes-3336Pelodiscus sinensis78.620.0 519
LLPS-Anc-2671Anolis carolinensis78.370.0 518
LLPS-Rhb-0173Rhinopithecus bieti78.165e-178 506
LLPS-Gaga-0340Gallus gallus77.671e-179 514
LLPS-Leo-2538Lepisosteus oculatus77.125e-176 501
LLPS-Orl-0218Oryzias latipes74.847e-171 488
LLPS-Scf-0525Scleropages formosus74.533e-170 487
LLPS-Asm-1623Astyanax mexicanus74.294e-167 479
LLPS-Icp-2097Ictalurus punctatus73.99e-170 486
LLPS-Xet-1699Xenopus tropicalis73.874e-169 484
LLPS-Pof-0636Poecilia formosa73.581e-170 489
LLPS-Tar-2274Takifugu rubripes72.966e-168 481
LLPS-Orn-0192Oreochromis niloticus72.643e-161 464
LLPS-Scm-1270Scophthalmus maximus72.011e-165 475
LLPS-Xim-1129Xiphophorus maculatus71.073e-164 473
LLPS-Dar-0251Danio rerio70.441e-162 467
LLPS-Mea-4089Mesocricetus auratus68.653e-135 396
LLPS-Gaa-2441Gasterosteus aculeatus67.44e-154 446
LLPS-Mod-0983Monodelphis domestica63.396e-85 265
LLPS-Cii-1000Ciona intestinalis60.85e-136 398
LLPS-Cis-1170Ciona savignyi60.744e-136 399
LLPS-Abg-0803Absidia glauca53.563e-99 305
LLPS-Mel-0939Melampsora laricipopulina53.283e-86 268
LLPS-Pug-0398Puccinia graminis52.354e-85 271
LLPS-Drm-0750Drosophila melanogaster51.984e-116 348
LLPS-Miv-1436Microbotryum violaceum49.837e-91 285
LLPS-Fuv-0504Fusarium verticillioides49.832e-88 280
LLPS-Crn-0340Cryptococcus neoformans49.334e-85 270
LLPS-Trv-0640Trichoderma virens49.136e-86 271
LLPS-Ved-0450Verticillium dahliae48.866e-63 210
LLPS-Fuo-0778Fusarium oxysporum48.661e-87 278
LLPS-Pytr-0357Pyrenophora triticirepentis48.623e-78 254
LLPS-Usm-1245Ustilago maydis48.69e-89 280
LLPS-Spr-0189Sporisorium reilianum48.333e-82 263
LLPS-Fus-1158Fusarium solani48.292e-85 271
LLPS-Zyt-0654Zymoseptoria tritici48.213e-86 269
LLPS-Trr-0565Trichoderma reesei48.11e-83 263
LLPS-Dos-0200Dothistroma septosporum47.873e-87 275
LLPS-Gag-1218Gaeumannomyces graminis47.712e-83 269
LLPS-Coo-0428Colletotrichum orbiculare47.62e-83 269
LLPS-Pyt-0305Pyrenophora teres47.593e-83 267
LLPS-Scs-0276Sclerotinia sclerotiorum47.549e-80 257
LLPS-Mao-0429Magnaporthe oryzae47.517e-84 268
LLPS-Cogr-1166Colletotrichum graminicola47.211e-85 275
LLPS-Lem-0743Leptosphaeria maculans47.211e-78 256
LLPS-Asn-1007Aspergillus nidulans47.041e-83 265
LLPS-Asfu-0515Aspergillus fumigatus46.951e-78 254
LLPS-Asc-0158Aspergillus clavatus46.867e-86 273
LLPS-Ast-0065Aspergillus terreus46.695e-86 271
LLPS-Cog-1211Colletotrichum gloeosporioides46.62e-84 270
LLPS-Asni-0922Aspergillus niger46.582e-83 265
LLPS-Lac-3338Latimeria chalumnae46.52e-80 255
LLPS-Blg-1279Blumeria graminis46.139e-77 248
LLPS-Osl-0677Ostreococcus lucimarinus46.068e-85 266
LLPS-Nec-0584Neurospora crassa45.763e-81 259
LLPS-Beb-0901Beauveria bassiana45.62e-82 263
LLPS-Scj-0147Schizosaccharomyces japonicus45.522e-84 267
LLPS-Nef-0682Neosartorya fischeri45.422e-78 253
LLPS-Aso-0178Aspergillus oryzae45.212e-84 267
LLPS-Asf-0437Aspergillus flavus45.212e-84 267
LLPS-Scp-0985Schizosaccharomyces pombe45.048e-82 259
LLPS-Kop-0979Komagataella pastoris44.732e-73 238
LLPS-Gas-1315Galdieria sulphuraria42.237e-75 245
LLPS-Scc-0941Schizosaccharomyces cryophilus41.671e-63 212
LLPS-Asg-0022Ashbya gossypii41.027e-71 231
LLPS-Ten-0311Tetraodon nigroviridis40.613e-66 224
LLPS-Meg-0424Meleagris gallopavo40.341e-64 221
LLPS-Cym-0011Cyanidioschyzon merolae40.287e-61 204
LLPS-Sac-0170Saccharomyces cerevisiae40.21e-65 218
LLPS-Fia-0351Ficedula albicollis40.02e-63 219
LLPS-Anp-0792Anas platyrhynchos39.272e-64 221
LLPS-Tag-3327Taeniopygia guttata39.271e-63 218
LLPS-Yal-0904Yarrowia lipolytica37.279e-50 175
LLPS-Phn-0500Phaeosphaeria nodorum33.021e-44 165