• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Fia-3018
RPGR

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Retinitis pigmentosa GTPase regulator
Gene Name: RPGR
Ensembl Gene: ENSFALG00000001581.1
Ensembl Protein: ENSFALP00000001649.1
Organism: Ficedula albicollis
Taxa ID: 59894
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSFALT00000001658.1ENSFALP00000001649.1
UniProtU3JFU5, U3JFU5_FICAL
GeneBankAGTO01011224, AGTO01001104

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVTECRGSAR  ESGAVFTFGK  SKFAEDIPSK  FWFKNDKPVL  ISCGDEHTAI  ITGKGKLYMF  60
61    GSNDWGQLGL  GSKNTVSKPT  CVKALKPEKP  KLAVCGRNHT  LVYTEKGNVY  AAGGNSEGQL  120
121   GLGDTEERTT  FHLISFFTNQ  HKIKQLSAGS  YTSAAVTEDG  QLFVWGDNSE  GQIGLASEAS  180
181   VSIPCKVDIG  KPIAFVSCGY  YHSALITGDG  ELYTFGEPVN  GKLGLFPEQL  KNNRVPQPVL  240
241   GIMEKVKKVA  CGGEHTVVLT  EKAVYTFGLG  QYGQLGHGTF  VFESSVPKPV  KHLKRHKICN  300
301   IACGENHTAV  IAENGLMFTF  GDGRHGKLGF  GEESFTNLFD  PTLCYNFLKF  TVLLVACGGC  360
361   HMLVFAAPRP  KGSEVLLEDL  FEPRLTATIP  QSSGDFVLAN  TLQLSAARMR  RRERERSPEQ  420
421   FARMAQTLPP  MGESFLKSSL  PVTSNTSPFW  FSATSRPKSE  SGRDGDHEKE  NNHQKDKPGE  480
481   VSSEQDSDNE  NTDRNLGDTT  DILNVTHAMK  LNPGDWSLKL  SPLQKQKEQN  LSGDEEIDDD  540
541   DDEEEEETEE  EEEEEEEEEE  EEEEEEEEEE  EEEEEEEEEE  EEEEEEEEEE  EEEEEEEEEE  600
601   EEEEEEEEEE  EEENVKEEEN  IEEEVEEKEE  TSKKKKT  637
Nucleotide CDS Sequence (FASTA)
1     ATGGTTACTG  AGTGTCGCGG  TTCGGCCCGC  GAATCAGGTG  CTGTTTTCAC  ATTCGGGAAA  60
61    AGCAAATTTG  CAGAAGATAT  TCCTAGCAAG  TTCTGGTTCA  AAAATGACAA  GCCTGTACTT  120
121   ATATCATGTG  GAGATGAACA  TACAGCTATT  ATTACAGGAA  AAGGCAAACT  CTATATGTTT  180
181   GGCAGTAATG  ACTGGGGCCA  GTTAGGACTA  GGATCGAAGA  ACACTGTCAG  CAAACCAACG  240
241   TGTGTTAAAG  CTTTAAAACC  AGAAAAACCA  AAACTTGCTG  TTTGTGGAAG  AAACCACACT  300
301   TTAGTTTACA  CAGAAAAAGG  AAATGTCTAT  GCTGCTGGAG  GAAACAGTGA  AGGCCAGTTG  360
361   GGATTAGGTG  ACACAGAGGA  AAGGACCACA  TTTCATTTAA  TTAGTTTTTT  TACCAACCAG  420
421   CACAAGATCA  AGCAACTATC  AGCTGGATCA  TACACCTCAG  CAGCAGTAAC  TGAGGATGGG  480
481   CAGCTCTTTG  TATGGGGTGA  TAATTCAGAA  GGTCAGATTG  GTCTGGCCAG  TGAAGCCTCT  540
541   GTCAGTATCC  CCTGTAAAGT  GGATATTGGA  AAACCTATTG  CCTTTGTATC  CTGTGGATAT  600
601   TATCATTCTG  CCCTGATTAC  AGGAGATGGT  GAGCTCTATA  CTTTTGGAGA  ACCTGTGAAT  660
661   GGGAAACTGG  GATTATTCCC  TGAACAGCTC  AAGAACAATA  GAGTCCCACA  GCCTGTCCTG  720
721   GGAATTATGG  AAAAGGTTAA  AAAAGTTGCT  TGTGGTGGAG  AACACACTGT  GGTGCTGACA  780
781   GAGAAAGCTG  TTTATACTTT  TGGCCTTGGA  CAATATGGAC  AGCTGGGACA  TGGAACTTTT  840
841   GTGTTTGAAA  GTTCAGTACC  GAAGCCTGTG  AAACATTTGA  AGAGGCATAA  AATATGTAAC  900
901   ATTGCATGTG  GGGAAAATCA  CACTGCTGTG  ATAGCAGAGA  ATGGCCTCAT  GTTTACTTTT  960
961   GGAGATGGAC  GACATGGCAA  GTTAGGATTT  GGAGAAGAGA  GTTTTACAAA  TTTGTTTGAT  1020
1021  CCCACTCTGT  GTTACAATTT  CTTGAAGTTC  ACAGTCCTTT  TGGTTGCTTG  TGGTGGTTGT  1080
1081  CACATGCTGG  TTTTTGCTGC  TCCAAGACCT  AAAGGATCTG  AAGTACTCTT  GGAAGATTTA  1140
1141  TTTGAGCCTC  GTTTGACTGC  TACAATCCCT  CAATCCAGTG  GGGACTTTGT  ACTAGCAAAC  1200
1201  ACTTTGCAAC  TATCAGCAGC  ACGAATGCGA  CGTCGAGAGA  GGGAAAGATC  ACCAGAGCAA  1260
1261  TTTGCTAGAA  TGGCACAAAC  TCTGCCTCCA  ATGGGGGAAA  GCTTCTTAAA  ATCTTCATTG  1320
1321  CCTGTGACAA  GCAACACCAG  CCCATTCTGG  TTTTCTGCAA  CAAGTCGTCC  TAAATCTGAA  1380
1381  TCTGGGAGGG  ATGGAGACCA  TGAAAAAGAA  AACAATCATC  AAAAAGATAA  ACCTGGTGAA  1440
1441  GTCTCTTCAG  AACAAGATTC  AGATAATGAA  AATACTGACA  GAAACCTTGG  GGATACAACT  1500
1501  GACATCCTAA  ATGTGACACA  TGCAATGAAG  TTGAATCCTG  GTGACTGGTC  CTTAAAATTA  1560
1561  TCACCACTCC  AAAAACAGAA  GGAACAAAAC  TTGTCTGGAG  ATGAAGAAAT  AGATGATGAT  1620
1621  GATGATGAGG  AAGAAGAAGA  AACAGAAGAA  GAAGAAGAAG  AAGAAGAAGA  AGAAGAAGAA  1680
1681  GAAGAAGAAG  AAGAAGAAGA  AGAAGAAGAA  GAAGAAGAAG  AAGAAGAAGA  AGAAGAAGAA  1740
1741  GAAGAAGAAG  AAGAAGAAGA  AGAAGAAGAA  GAAGAAGAAG  AAGAAGAAGA  AGAAGAAGAA  1800
1801  GAAGAAGAAG  AAGAAGAAGA  AGAAGAAGAA  GAAGAAGAAA  ACGTCAAAGA  AGAAGAAAAC  1860
1861  ATAGAAGAAG  AAGTAGAAGA  AAAAGAAGAA  ACATCGAAGA  AGAAGAAAAC  GTAG  1914

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anp-2435Anas platyrhynchos81.920.0 858
LLPS-Gaga-1177Gallus gallus80.650.0 838
LLPS-Anc-3994Anolis carolinensis79.330.0 599
LLPS-Ora-2469Ornithorhynchus anatinus65.410.0 667
LLPS-Tar-4003Takifugu rubripes64.743e-174 525
LLPS-Mod-1864Monodelphis domestica64.70.0 671
LLPS-Mup-2874Mustela putorius furo63.480.0 629
LLPS-Aim-4373Ailuropoda melanoleuca63.230.0 617
LLPS-Fec-0551Felis catus62.860.0 629
LLPS-Urm-3683Ursus maritimus62.840.0 598
LLPS-Ict-4297Ictidomys tridecemlineatus62.710.0 612
LLPS-Nol-2671Nomascus leucogenys62.240.0 607
LLPS-Aon-4454Aotus nancymaae62.170.0 593
LLPS-Pap-2684Pan paniscus62.120.0 617
LLPS-Mam-3062Macaca mulatta62.080.0 613
LLPS-Pat-0719Pan troglodytes62.050.0 619
LLPS-Hos-2617Homo sapiens61.860.0 614
LLPS-Caf-1392Canis familiaris61.640.0 615
LLPS-Ten-0241Tetraodon nigroviridis61.649e-163 482
LLPS-Sus-1013Sus scrofa61.480.0 603
LLPS-Caj-3626Callithrix jacchus61.410.0 593
LLPS-Ova-2052Ovis aries59.920.0 598
LLPS-Bot-2335Bos taurus59.920.0 592
LLPS-Myl-1421Myotis lucifugus59.850.0 606
LLPS-Ran-1772Rattus norvegicus59.760.0 577
LLPS-Loa-3352Loxodonta africana59.010.0 581
LLPS-Eqc-3995Equus caballus58.980.0 565
LLPS-Mea-4482Mesocricetus auratus58.820.0 588
LLPS-Dio-2960Dipodomys ordii58.730.0 601
LLPS-Rhb-4188Rhinopithecus bieti58.670.0 567
LLPS-Orn-1116Oreochromis niloticus58.650.0 594
LLPS-Mum-4479Mus musculus58.610.0 604
LLPS-Cap-4065Cavia porcellus58.580.0 592
LLPS-Scf-1654Scleropages formosus58.320.0 600
LLPS-Leo-1333Lepisosteus oculatus58.240.0 617
LLPS-Asm-1053Astyanax mexicanus57.730.0 606
LLPS-Orc-3552Oryctolagus cuniculus57.550.0 582
LLPS-Fud-2467Fukomys damarensis57.50.0 558
LLPS-Gaa-2935Gasterosteus aculeatus56.750.0 570
LLPS-Dar-3293Danio rerio55.680.0 573
LLPS-Icp-3529Ictalurus punctatus55.580.0 569
LLPS-Pof-3288Poecilia formosa54.380.0 537
LLPS-Maf-0441Macaca fascicularis54.082e-89 301
LLPS-Orl-2209Oryzias latipes53.579e-89 307
LLPS-Xet-3804Xenopus tropicalis53.361e-180 537
LLPS-Poa-3991Pongo abelii52.83e-90 290
LLPS-Xim-0673Xiphophorus maculatus52.072e-162 485
LLPS-Scm-2637Scophthalmus maximus51.326e-144 441
LLPS-Man-1247Macaca nemestrina48.584e-122 388
LLPS-Cas-3217Carlito syrichta47.272e-75 263
LLPS-Cii-1067Ciona intestinalis41.534e-1479.3
LLPS-Brd-1375Brachypodium distachyon37.412e-1273.9
LLPS-Sah-4068Sarcophilus harrisii37.182e-40 162
LLPS-Met-2113Medicago truncatula36.723e-1376.3
LLPS-Bro-2902Brassica oleracea36.59e-1375.1
LLPS-Hov-0479Hordeum vulgare36.53e-1376.3
LLPS-Tra-2082Triticum aestivum36.53e-1376.6
LLPS-Lep-1041Leersia perrieri36.58e-1478.2
LLPS-Nia-1177Nicotiana attenuata36.222e-1170.9
LLPS-Otg-1785Otolemur garnettii36.228e-40 160
LLPS-Cea-0179Cercocebus atys36.224e-40 161
LLPS-Chs-2052Chlorocebus sabaeus36.224e-40 161
LLPS-Mal-2500Mandrillus leucophaeus36.224e-40 161
LLPS-Paa-3359Papio anubis36.224e-40 161
LLPS-Art-2726Arabidopsis thaliana36.173e-1376.3
LLPS-Arl-1629Arabidopsis lyrata36.173e-1376.3
LLPS-Lac-2218Latimeria chalumnae36.134e-40 161
LLPS-Zem-2489Zea mays35.972e-1376.6
LLPS-Gog-2442Gorilla gorilla35.98e-40 160
LLPS-Ors-0355Oryza sativa35.774e-1376.3
LLPS-Org-1310Oryza glaberrima35.774e-1376.3
LLPS-Orr-1091Oryza rufipogon35.774e-1376.3
LLPS-Orni-2312Oryza nivara35.774e-1376.3
LLPS-Mua-2482Musa acuminata35.772e-1480.5
LLPS-Orb-0597Oryza barthii35.774e-1376.3
LLPS-Ori-1213Oryza indica35.774e-1376.3
LLPS-Orgl-1973Oryza glumaepatula35.774e-1376.3
LLPS-Meg-0260Meleagris gallopavo35.587e-39 157
LLPS-Tag-3324Taeniopygia guttata35.585e-39 158
LLPS-Vir-1677Vigna radiata35.343e-33 136
LLPS-Pes-2420Pelodiscus sinensis35.268e-38 154
LLPS-Sob-2022Sorghum bicolor35.26e-40 156
LLPS-Gas-1265Galdieria sulphuraria35.029e-25 111
LLPS-Drm-2256Drosophila melanogaster34.982e-37 154
LLPS-Brn-3408Brassica napus34.754e-1272.8
LLPS-Sei-0110Setaria italica34.754e-1376.3
LLPS-Glm-1099Glycine max34.561e-39 155
LLPS-Thc-2288Theobroma cacao34.22e-40 157
LLPS-Pot-1563Populus trichocarpa34.14e-42 162
LLPS-Cus-2234Cucumis sativus34.11e-41 161
LLPS-Viv-0380Vitis vinifera34.044e-1169.7
LLPS-Via-1846Vigna angularis33.893e-38 151
LLPS-Php-1416Physcomitrella patens33.873e-1067.8
LLPS-Phv-2244Phaseolus vulgaris33.673e-38 151
LLPS-Brr-1185Brassica rapa33.613e-25 115
LLPS-Mae-1975Manihot esculenta33.553e-39 154
LLPS-Dac-0973Daucus carota33.334e-0963.2
LLPS-Prp-1112Prunus persica33.231e-39 155
LLPS-Orbr-2335Oryza brachyantha33.114e-39 153
LLPS-Sol-1716Solanum lycopersicum33.13e-31 134
LLPS-Orp-1921Oryza punctata32.933e-1273.6
LLPS-Cae-0461Caenorhabditis elegans32.671e-27 123
LLPS-Hea-1521Helianthus annuus32.626e-1065.9
LLPS-Coc-1146Corchorus capsularis32.269e-39 152
LLPS-Gor-0345Gossypium raimondii32.132e-35 143
LLPS-Orm-1818Oryza meridionalis32.034e-28 121
LLPS-Amt-1412Amborella trichopoda31.162e-31 134
LLPS-Tru-1457Triticum urartu31.078e-32 136
LLPS-Cis-0140Ciona savignyi27.814e-28 121