LLPS-Fec-a101
PANX
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pannexin |
| Gene Name: | PANX, PANX2 |
| Ensembl Gene: | ENSFCAG00000024028.3 |
| Ensembl Protein: | ENSFCAP00000019781.3 |
| Organism: | Felis catus |
| Taxa ID: | 9685 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Structural component of the gap junctions and the hemichannels. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSFCAT00000028272.3 | ENSFCAP00000019781.3 |
| UniProt | M3WZJ0, M3WZJ0_FELCA | |
| GeneBank | AANG04003413 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MHHLLQQSAD MATALLAGEK LRELILPGAQ DDKAGALAAL LLQLKLELPF DRVVTIGTVL 60 61 VPILLVTLVF TKNFAEEPIY CYTPHNFTRD QALYARGYCW TELRDALPGV DASLWPSLFE 120 121 HKLLPYSLLA FAAIMYVPAL GWEFLASTRL TSELNFLLQE IDNCYHRAAE GRAPKIEKQI 180 181 QSKGPGITER ERREIIENAE KEKSPEQNLF EKYLERRGRS NFLAKLYLAR HLLILLLSVA 240 241 PISYLCTYYA TQKQNEFTCA LGASPDGPAG GAAAGAAAVR VSCKLPSVQL QRIVAGVDIV 300 301 LLCAMNLIIL VNLIHLFIFR KSNFIFDKLH KVGIKTRRQW RRSQFCDINI LAMFCNENRD 360 361 HIKSLNRLDF ITNESDLMYD NVVRQLLAAL AQSNHDATPT VRDAGVQTVD PSANPAEPEG 420 421 SAEPPVVKRP RKKMKWIPTS NPLPQPFKEP LAIMRVENSK AEKPKPVRRK TATDTLIAPL 480 481 LDAGARAAHH YKGGGGDAGP APDKKHARHF SLDVHPYILG TKKAKPEAVP AAALPASRSQ 540 541 EGGFLSQAEE CALGLAAAPT KDAPLPEKEI LYPAEPARAT LPPGGPFHVC SPPAAPATAP 600 601 LSPASLGKPD PLAILSRNAT HPLLHISTLY EAREEEDGGP RAPPDVGSLI AIPPPQQMLI 660 661 ATFDEPRTVV STVEF 675 |
| Nucleotide CDS Sequence (FASTA) |
1 CCCATTTACT GCTACACGCC GCACAACTTC ACTCGCGACC AGGCGCTGTA CGCTCGCGGC 60 61 TACTGCTGGA CGGAGCTGCG GGACGCACTG CCCGGCGTGG ACGCCAGCCT GTGGCCGTCG 120 121 CTGTTTGAGC ACAAGCTGCT GCCCTACTCG CTGCTGGCCT TCGCGGCCAT CATGTACGTC 180 181 CCTGCGCTGG GCTGGGAGTT CCTGGCCTCC ACCCGCCTCA CCTCGGAGCT CAACTTCCTG 240 241 CTGCAGGAGA TCGACAACTG CTACCACCGC GCCGCCGAGG GCCGCGCCCC CAAGATCGAG 300 301 AAGCAGATCC AGTCCAAGGG GCCCGGCATC ACGGAGCGCG AGAGGCGCGA GATCATCGAG 360 361 AACGCCGAGA AGGAGAAGAG CCCGGAGCAG AACCTGTTCG AGAAGTACCT GGAGCGCCGC 420 421 GGCCGCAGCA ACTTCCTGGC CAAGCTGTAC CTGGCGCGGC ACCTGCTGAT CCTGCTGCTC 480 481 AGCGTGGCGC CCATCTCCTA CCTGTGCACC TACTACGCCA CGCAGAAGCA GAACGAGTTC 540 541 ACGTGCGCGC TGGGCGCGTC CCCGGACGGG CCGGCAGGGG GCGCGGCGGC GGGGGCGGCC 600 601 GCCGTGCGCG TCAGCTGCAA GCTGCCGTCC GTGCAGCTGC AGCGCATCGT GGCGGGCGTG 660 661 GACATCGTGC TGCTGTGCGC CATGAACCTC ATCATCCTCG TCAACCTCAT CCACCTCTTC 720 721 ATCTTCCGCA AGAGCAACTT CATCTTCGAC AAGCTGCACA AGGTGGGCAT CAAGACGCGC 780 781 CGGCAGTGGC GCCGCTCGCA GTTCTGCGAC ATCAACATCC TGGCCATGTT CTGCAACGAG 840 841 AACCGCGACC ACATCAAGTC GCTCAACCGG CTGGACTTCA TCACCAACGA GAGCGACCTC 900 901 ATCGCCCCCG ACAAGAAGCA TGCGCGCCAC TTTTCCCTGG ACGTGCACCC CTACATCCTG 960 961 GGCACCAAGA AGGCCAAGCC CGAGGCCGTG CCCGCCGCCG CCCTGCCCGC CTCCCGG 1017 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Gap junction | |
Cellular Component | Integral component of membrane | |
Cellular Component | Plasma membrane | |
Molecular Function | Wide pore channel activity | |
Biological Process | Cation transport | |
Biological Process | Cell-cell signaling | |
Biological Process | Positive regulation of interleukin-1 secretion | |
Biological Process | Response to ischemia |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a099 | Homo sapiens | 0.0 | 1160 | undefined |
| LLPS-Mum-a102 | Mus musculus | 0.0 | 1167 | undefined |