• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Ere-0985
PFN2

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Profilin
Gene Name: PFN2
Ensembl Gene: ENSEEUG00000012801.1
Ensembl Protein: ENSEEUP00000011650.1
Organism: Erinaceus europaeus
Taxa ID: 9365
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MAGWQSYVDN  LMCDGCCQEA  AIVGYCDAYV  WAATAGGVFQ  SITPVEIDMI  VGKDREGFFT  60
61    NGLTLGAKKC  SVIRDSLYVD  GDCTMDIRTK  SQGGEPTYNV  AVGRAGRVLV  FVMGKEGVHG  120
121   GGLNKKAYSM  AKYLRDSGF  139
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGGGT  GGCAGAGCTA  CGTGGACAAC  CTGATGTGCG  ATGGCTGCTG  TCAGGAGGCC  60
61    GCCATTGTCG  GCTACTGCGA  CGCCTACGTG  TGGGCCGCCA  CGGCGGGGGG  CGTCTTCCAG  120
121   AGCATCACGC  CAGTAGAAAT  AGATATGATT  GTAGGAAAAG  ATCGGGAAGG  CTTCTTTACC  180
181   AATGGCTTGA  CTCTTGGCGC  CAAGAAGTGC  TCGGTGATCA  GAGATAGTCT  GTACGTCGAC  240
241   GGCGACTGCA  CAATGGACAT  TCGGACAAAG  AGTCAAGGTG  GGGAGCCAAC  GTACAACGTC  300
301   GCCGTGGGCA  GAGCTGGCAG  AGTCTTGGTC  TTTGTAATGG  GAAAAGAAGG  GGTCCATGGA  360
361   GGCGGATTGA  ATAAGAAGGC  ATACTCAATG  GCAAAATACT  TGAGAGACTC  TGGGTTCTAG  420

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Meg-2419Meleagris gallopavo100.06e-64 197
LLPS-Pap-4564Pan paniscus100.01e-59 186
LLPS-Anp-0960Anas platyrhynchos100.05e-64 197
LLPS-Caf-2341Canis familiaris100.01e-59 186
LLPS-Fud-2974Fukomys damarensis100.01e-59 186
LLPS-Aim-2969Ailuropoda melanoleuca100.05e-64 197
LLPS-Mum-3201Mus musculus99.291e-96 281
LLPS-Sus-2228Sus scrofa99.291e-96 281
LLPS-Bot-1375Bos taurus99.291e-96 281
LLPS-Fia-2006Ficedula albicollis98.961e-62 194
LLPS-Otg-1910Otolemur garnettii98.572e-96 281
LLPS-Cap-3839Cavia porcellus98.572e-96 281
LLPS-Gaga-0486Gallus gallus98.572e-96 281
LLPS-Chs-4100Chlorocebus sabaeus98.571e-97 293
LLPS-Caj-1196Callithrix jacchus98.572e-95 284
LLPS-Poa-0049Pongo abelii98.453e-87 257
LLPS-Mod-0302Monodelphis domestica97.863e-96 280
LLPS-Anc-0597Anolis carolinensis97.865e-96 280
LLPS-Ran-1665Rattus norvegicus95.623e-91 268
LLPS-Fec-2862Felis catus94.856e-88 261
LLPS-Ora-3516Ornithorhynchus anatinus94.291e-92 271
LLPS-Hos-1182Homo sapiens94.127e-88 261
LLPS-Pat-1137Pan troglodytes94.127e-88 261
LLPS-Man-1804Macaca nemestrina94.127e-88 261
LLPS-Eqc-2752Equus caballus94.121e-87 260
LLPS-Mam-0737Macaca mulatta94.127e-88 261
LLPS-Nol-4632Nomascus leucogenys94.128e-88 261
LLPS-Maf-1804Macaca fascicularis94.127e-88 261
LLPS-Aon-0652Aotus nancymaae94.127e-88 261
LLPS-Gog-0587Gorilla gorilla94.127e-88 261
LLPS-Paa-0362Papio anubis94.124e-88 261
LLPS-Cea-4258Cercocebus atys93.482e-88 263
LLPS-Myl-4089Myotis lucifugus93.483e-55 176
LLPS-Mup-0484Mustela putorius furo92.811e-85 255
LLPS-Tag-1571Taeniopygia guttata90.431e-54 173
LLPS-Mal-2855Mandrillus leucophaeus86.139e-78 234
LLPS-Leo-2036Lepisosteus oculatus85.44e-81 243
LLPS-Icp-1995Ictalurus punctatus83.942e-77 234
LLPS-Scf-3411Scleropages formosus83.942e-79 238
LLPS-Orc-0517Oryctolagus cuniculus83.331e-57 181
LLPS-Orn-3612Oreochromis niloticus82.486e-78 234
LLPS-Scm-4035Scophthalmus maximus81.028e-77 234
LLPS-Pof-2594Poecilia formosa80.66e-74 223
LLPS-Ten-3575Tetraodon nigroviridis80.299e-76 228
LLPS-Rhb-3474Rhinopithecus bieti79.371e-62 196
LLPS-Xet-1275Xenopus tropicalis79.291e-77 233
LLPS-Gaa-0407Gasterosteus aculeatus78.838e-74 224
LLPS-Orl-0871Oryzias latipes78.13e-74 224
LLPS-Asm-0736Astyanax mexicanus78.13e-73 222
LLPS-Lac-2481Latimeria chalumnae77.863e-74 224
LLPS-Dar-4087Danio rerio77.371e-72 221
LLPS-Cas-1360Carlito syrichta77.312e-55 177
LLPS-Tar-3778Takifugu rubripes75.181e-71 218
LLPS-Ova-2982Ovis aries71.531e-58 190
LLPS-Xim-2892Xiphophorus maculatus70.84e-68 209
LLPS-Ict-0098Ictidomys tridecemlineatus62.144e-58 183
LLPS-Sah-1243Sarcophilus harrisii62.143e-59 186
LLPS-Urm-3174Ursus maritimus61.462e-37 129
LLPS-Mea-2437Mesocricetus auratus61.439e-57 180
LLPS-Dio-3594Dipodomys ordii61.433e-57 181
LLPS-Loa-0614Loxodonta africana60.711e-56 180
LLPS-Pes-1002Pelodiscus sinensis60.01e-55 177
LLPS-Tut-0716Tursiops truncatus51.433e-41 140
LLPS-Arl-2737Arabidopsis lyrata33.571e-0648.1
LLPS-Glm-2392Glycine max33.332e-0750.1