LLPS-Eqc-a103
PANX2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pannexin |
| Gene Name: | PANX2, PANX |
| Ensembl Gene: | ENSECAG00000021702.2 |
| Ensembl Protein: | ENSECAP00000019108.2 |
| Organism: | Equus caballus |
| Taxa ID: | 9796 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Structural component of the gap junctions and the hemichannels. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSECAT00000023085.2 | ENSECAP00000019108.2 |
| UniProt | F6WMB5, F6WMB5_HORSE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MHHLLEQSAD MATALLAGEK LRELILPGAQ DDKAGALAAL LLQLKLELPF DRVVTIGTVL 60 61 VPILLVTLVF TKNFAEEPIY CYTPHNFTRD QALYARGYCW TELRDALPGV DASLWPSLFE 120 121 HKLLPYSLLA FAAIMYVPAL GWEFLASTRL TSELNFLLQE IDNCYHRAAE GRAPKIEKQI 180 181 QSKGPGITER ERREIIENAE KEKSPEQNLF EKYLERRGRS NFLAKLYLAR HLLILLLSVA 240 241 PISYLCTYYA TQKQNEFTCA LGASPDGPAG GGGPAVRVSC KLPSVQLQRI VAGVDIVLLC 300 301 AMNLIILVNL IHLFIFRKSN FIFDKLHKVG IKTRRQWRRS QFCDINILAM FCNENRDHIK 360 361 SLNRLDFITN ESDLMYDNVV RQLLAALAQS NHDATPTVRD TGVQTVDPSA NPAEPEGSAE 420 421 PPVVKRPRKK MKWIPTSNPL PQPFKEQLAI MRVENSKAEK PKPVRRKTAT DTLIAPLLDA 480 481 GARATHYKGG PTPGPGAAPD KKHARHFSLD VHPYILGTKK AKPEAVPTAL PASRSQEGGF 540 541 LSQAEECGLA LAAAPTKDAS LPEKEILYTG EPARGSLPPG GPFHVCSPPT APATAPLSPA 600 601 SLGKADPLAI LSRNATHPLL HISTLYEARE EEDGGPRVPP DVGSLIAIPP PQQILIATFD 660 661 EPRTVVSTVE F 671 |
| Nucleotide CDS Sequence (FASTA) |
1 GCAGAGGAGC CCATTTACTG CTACACGCCA CACAACTTCA CCCGCGACCA GGCGCTGTAT 60 61 GCTCGCGGCT ACTGCTGGAC GGAGCTGCGG GATGCGCTGC CCGGTGTGGA CGCCAGCCTG 120 121 TGGCCGTCGC TGTTTGAGCA CAAGCTGCTG CCCTACTCGC TGCTGGCCTT CGCGGCCATC 180 181 ATGTACGTCC CCGCGCTGGG CTGGGAGTTC CTGGCCTCCA CCCGCCTCAC CTCGGAGCTC 240 241 AACTTCCTGC TGCAAGAGAT CGATAACTGC TACCACCGGG CCGCCGAGGG CCGCGCTCCC 300 301 AAGATCGAGA AGCAGATCCA GTCCAAGGGC CCCGGCATCA CAGAGCGCGA GAGGCGCGAG 360 361 ATCATCGAGA ATGCGGAGAA GGAGAAGAGC CCAGAGCAGA ACCTGTTCGA GAAGTACCTG 420 421 GAGCGCCGCG GCCGCAGCAA CTTCCTGGCC AAGCTGTACC TGGCGCGGCA CCTGCTCATC 480 481 CTGCTGCTCA GTGTGGCGCC CATCTCCTAC CTGTGCACCT ACTACGCCAC CCAGAAGCAG 540 541 AACGAGTTCA CCTGCGCGCT GGGCGCATCC CCGGACGGGC CTGCGGGCGG CGGGGGCCCA 600 601 GCCGTGCGCG TCAGCTGCAA GCTGCCGTCA GTGCAGCTGC AGCGCATCGT GGCGGGCGTC 660 661 GACATCGTGC TGCTCTGCGC CATGAACCTC ATCATCCTCG TCAACCTCAT CCACCTCTTC 720 721 ATCTTCCGCA AGAGCAACTT CATCTTCGAC AAGCTGCACA AGGTGGGCAT CAAGACGCGC 780 781 CGGCAGTGGC GCCGCTCGCA GTTCTGCGAC ATCAACATCC TGGCCATGTT CTGCAACGAG 840 841 AACCGCGACC ACATCAAGTC GCTCAACCGG CTGGACTTCA TCACCAACGA GAGCGACCTC 900 901 ATGTACGACA ACGTGGTGCG GCAGCTGCTG GCCGCCCTGG CCCAGTCCAA CCACGACGCC 960 961 ACGCCCACCG TGCGTGACAC GGGCGTGCAG ACCGTGGACC CCAGCGCCAA CCCCGCCGAG 1020 1021 CCCGAGGGCT CCGCCGAGCC GCCCGTGGTC AAGCGGCCCC GCAAGAAGAT GAAGTGGATC 1080 1081 CCCACCAGCA ACCCGCTGCC CCAGCCCTTC AAGGAGCAGC TGGCCATCAT GCGCGTGGAG 1140 1141 AACAGCAAGG CCGAGAAGCC CAAGCCCGTG CGCCGCAAGA CGGCCACGGA CACGCTGATC 1200 1201 GCGCCGCTGC TGGACGCGGG TGCGCGCGCA ACGCACTACA AGGGCGGCCC CACCCCGGGC 1260 1261 CCGGGCGCCG CCCCCGACAA GAAGCATGCC CGCCACTTCT CCCTGGACGT GCACCCCTAC 1320 1321 ATCCTGGGCA CCAAGAAGGC CAAGCCCGAG GCCGTGCCCA CCGCCCTGCC CGCCTCCCGG 1380 1381 AGCCAGGAAG GGGGCTTCCT GTCCCAGGCG GAGGAGTGCG GGCTGGCCCT GGCCGCTGCA 1440 1441 CCCACCAAAG ATGCTTCGCT CCCTGAGAAG GAAATCCTGT ACACAGGAGA GCCGGCTCGG 1500 1501 GGCTCGCTTC CCCCCGGGGG CCCGTTTCAC GTCTGTTCAC CCCCGACAGC CCCCGCCACC 1560 1561 GCTCCTCTGT CACCAGCCAG CCTGGGCAAG GCTGACCCCC TCGCCATCCT GAGCCGCAAT 1620 1621 GCCACCCACC CACTGCTGCA CATCAGCACC CTGTACGAGG CCCGGGAGGA GGAGGACGGG 1680 1681 GGTCCCCGTG TGCCCCCGGA CGTGGGCAGC CTCATTGCCA TCCCCCCGCC ACAGCAGATC 1740 1741 CTCATTGCCA CTTTTGACGA GCCGAGGACA GTAGTGAGCA CTGTGGAGTT CTGA 1794 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Gap junction | |
Cellular Component | Integral component of membrane | |
Cellular Component | Plasma membrane | |
Molecular Function | Wide pore channel activity | |
Biological Process | Cation transport | |
Biological Process | Cell-cell signaling | |
Biological Process | Positive regulation of interleukin-1 secretion | |
Biological Process | Response to ischemia |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a099 | Homo sapiens | 0.0 | 1196 | undefined |
| LLPS-Mum-a102 | Mus musculus | 0.0 | 1198 | undefined |