• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-3609
RIOK2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: RIO kinase 2
Gene Name: RIOK2
Ensembl Gene: ENSECAG00000018441.2
Ensembl Protein: ENSECAP00000027873.1
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGKVNVAKLR  YMSRDDFRVL  TAVEMGMKNH  EIVPCSLVAS  IASLKHGGCN  KVLRELVKHK  60
61    LIAWERTKTV  QGYRLTNAGY  DYLALKTLSS  RQVVESVGNQ  MGVGKESDIY  IVANEEGQQF  120
121   ALKLHRLGRT  SFRNLKNKRD  YHKHRRNMSW  LYLSRLSAMK  EFAYMKALYE  RKFPVPKPID  180
181   YNRHAVVMEL  INGYPLCQIH  HVEDPASVYD  EAMELIVRLA  NHGLIHGDFN  EFNLILDKDD  240
241   HITMIDFPQM  VSTSHPNAEW  YFDRDVKCIR  DFFMKRFSYE  SELYPSFSDV  RREDCLDVEV  300
301   CASGCAEEMQ  AGDELLPPLG  PDDENTETEE  RSECSSDEEV  SEKAKVCRSE  NESERNSGDE  360
361   LVACCCRSAG  DLEQIKEDNL  SEGSADAHNF  EMTELSQALE  EIKGQVVENN  SVTEFSGETN  420
421   RTENDTRQDG  KTGRGGVPTG  SAEGEDECPL  LIALSSLNRG  FRPFRDEENI  EDIKQRRTRT  480
481   LSVTSAGSVV  SCSTIPPELV  KQKVKRQLTK  QQKSAVRRRL  QKGEANIFTK  QQRENMQNIK  540
541   SSLEAASLWG  E  551
Nucleotide CDS Sequence (FASTA)
1     ATGGGGAAGG  TGAACGTGGC  CAAGTTGCGT  TACATGAGTC  GGGATGATTT  CAGGGTCCTG  60
61    ACCGCGGTTG  AGATGGGCAT  GAAGAACCAT  GAGATAGTGC  CCTGCAGTTT  GGTTGCGTCC  120
121   ATAGCCAGCC  TTAAACATGG  TGGCTGCAAT  AAAGTGTTAA  GAGAATTAGT  GAAACATAAG  180
181   CTCATAGCTT  GGGAGCGTAC  CAAAACTGTC  CAGGGCTATC  GGTTGACAAA  TGCAGGCTAT  240
241   GATTACCTGG  CTTTGAAAAC  ACTTTCTTCT  AGACAGGTAG  TTGAGTCTGT  CGGAAACCAG  300
301   ATGGGTGTTG  GCAAAGAATC  TGATATTTAC  ATTGTTGCAA  ATGAAGAAGG  GCAGCAGTTT  360
361   GCATTGAAGC  TTCACAGACT  GGGAAGAACC  TCCTTTCGAA  ATCTGAAGAA  CAAGCGTGAT  420
421   TACCATAAAC  ACAGGCGTAA  CATGTCATGG  CTTTATTTAT  CTCGTCTCTC  TGCCATGAAA  480
481   GAATTTGCCT  ACATGAAGGC  ATTGTATGAG  AGGAAATTTC  CAGTTCCAAA  GCCAATTGAT  540
541   TATAATCGCC  ATGCAGTAGT  CATGGAACTC  ATAAATGGCT  ATCCTCTATG  TCAGATACAC  600
601   CACGTTGAAG  ATCCTGCATC  AGTATATGAT  GAAGCTATGG  AACTAATTGT  CAGACTTGCA  660
661   AATCATGGAC  TGATTCATGG  AGATTTCAAT  GAATTCAATC  TCATTTTGGA  TAAAGATGAC  720
721   CACATCACCA  TGATTGATTT  TCCACAAATG  GTTTCAACTT  CTCATCCCAA  TGCCGAATGG  780
781   TATTTTGACA  GAGATGTTAA  ATGCATTAGA  GATTTCTTCA  TGAAACGTTT  CAGCTATGAA  840
841   AGTGAGCTTT  ATCCATCCTT  TAGTGATGTC  AGGAGGGAGG  ACTGTCTTGA  TGTGGAGGTT  900
901   TGTGCCAGCG  GCTGCGCCGA  GGAGATGCAG  GCAGGCGATG  AGCTGCTTCC  TCCACTGGGT  960
961   CCGGATGATG  AAAACACTGA  AACAGAGGAG  CGCTCTGAAT  GCTCGTCTGA  TGAAGAGGTG  1020
1021  TCAGAGAAAG  CAAAGGTTTG  CAGATCAGAA  AATGAAAGTG  AACGGAACTC  TGGAGATGAA  1080
1081  TTAGTTGCCT  GCTGTTGCAG  ATCAGCTGGA  GACCTTGAAC  AAATAAAGGA  AGACAATTTG  1140
1141  TCAGAGGGCA  GTGCTGATGC  ACACAATTTT  GAAATGACTG  AACTCAGTCA  AGCTTTAGAA  1200
1201  GAAATAAAAG  GGCAGGTTGT  TGAAAACAAT  TCTGTAACTG  AGTTTTCTGG  GGAGACAAAC  1260
1261  AGAACTGAAA  ATGACACCAG  GCAAGACGGT  AAGACAGGTC  GCGGAGGAGT  GCCCACGGGC  1320
1321  TCTGCAGAGG  GTGAAGATGA  GTGCCCTCTT  CTGATTGCCT  TGTCGTCGCT  GAACAGAGGC  1380
1381  TTCAGGCCTT  TCAGAGATGA  AGAAAATATT  GAAGATATTA  AGCAACGTAG  AACAAGAACA  1440
1441  CTGAGCGTTA  CTTCTGCGGG  CAGTGTTGTA  AGCTGTTCAA  CAATTCCTCC  GGAACTGGTG  1500
1501  AAGCAGAAGG  TGAAACGTCA  ATTGACAAAA  CAGCAAAAGT  CAGCTGTCAG  ACGTCGATTG  1560
1561  CAGAAAGGAG  AAGCAAATAT  ATTTACCAAG  CAGCAGAGGG  AAAACATGCA  AAATATTAAA  1620
1621  TCCAGCTTGG  AAGCAGCCAG  CTTGTGGGGA  GAGTAA  1656

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sus-2293Sus scrofa99.457e-129 382
LLPS-Mea-3151Mesocricetus auratus95.561e-2098.2
LLPS-Myl-4354Myotis lucifugus90.220.01023
LLPS-Anp-0315Anas platyrhynchos89.691e-53 182
LLPS-Urm-3495Ursus maritimus88.040.01009
LLPS-Mup-1066Mustela putorius furo87.680.0 998
LLPS-Poa-2975Pongo abelii87.50.0 992
LLPS-Rhb-1500Rhinopithecus bieti87.50.0 995
LLPS-Hos-4867Homo sapiens87.50.0 993
LLPS-Ova-0494Ovis aries87.320.0 987
LLPS-Aim-2258Ailuropoda melanoleuca87.320.0 996
LLPS-Gog-3345Gorilla gorilla87.320.0 993
LLPS-Nol-4219Nomascus leucogenys87.160.0 989
LLPS-Mam-4107Macaca mulatta87.140.0 986
LLPS-Man-1181Macaca nemestrina87.140.0 986
LLPS-Paa-4120Papio anubis87.140.0 990
LLPS-Bot-3320Bos taurus87.140.0 992
LLPS-Cea-3629Cercocebus atys87.140.0 989
LLPS-Pat-2832Pan troglodytes86.960.0 989
LLPS-Maf-3910Macaca fascicularis86.780.0 983
LLPS-Mal-2180Mandrillus leucophaeus86.090.0 865
LLPS-Ict-0760Ictidomys tridecemlineatus86.050.0 974
LLPS-Orc-1619Oryctolagus cuniculus86.050.0 976
LLPS-Loa-2925Loxodonta africana86.050.0 988
LLPS-Cas-0201Carlito syrichta85.690.0 983
LLPS-Aon-2096Aotus nancymaae85.690.0 976
LLPS-Caf-4488Canis familiaris85.330.0 967
LLPS-Fec-2610Felis catus85.140.0 978
LLPS-Caj-2491Callithrix jacchus84.420.0 952
LLPS-Chs-3455Chlorocebus sabaeus83.510.0 642
LLPS-Pap-3098Pan paniscus83.330.0 919
LLPS-Dio-3830Dipodomys ordii83.150.0 929
LLPS-Cap-3166Cavia porcellus82.790.0 942
LLPS-Fud-3284Fukomys damarensis82.580.0 935
LLPS-Scf-2695Scleropages formosus82.240.0 578
LLPS-Ran-4668Rattus norvegicus81.160.0 936
LLPS-Mum-4302Mus musculus80.80.0 915
LLPS-Scm-3493Scophthalmus maximus80.690.0 570
LLPS-Otg-3792Otolemur garnettii80.110.0 894
LLPS-Tar-0600Takifugu rubripes79.440.0 566
LLPS-Orl-1385Oryzias latipes79.130.0 560
LLPS-Gaa-0636Gasterosteus aculeatus77.950.0 550
LLPS-Mod-3819Monodelphis domestica73.930.0 811
LLPS-Sah-2810Sarcophilus harrisii73.350.0 798
LLPS-Ora-2380Ornithorhynchus anatinus70.280.0 744
LLPS-Cii-0676Ciona intestinalis68.892e-149 446
LLPS-Spr-1452Sporisorium reilianum68.092e-0963.9
LLPS-Anc-2847Anolis carolinensis67.50.0 767
LLPS-Pes-3181Pelodiscus sinensis66.960.0 776
LLPS-Tag-2140Taeniopygia guttata65.190.0 728
LLPS-Gaga-0616Gallus gallus65.00.0 730
LLPS-Leo-3036Lepisosteus oculatus64.980.0 719
LLPS-Fia-3093Ficedula albicollis64.220.0 684
LLPS-Asm-0970Astyanax mexicanus64.180.0 706
LLPS-Xet-2473Xenopus tropicalis63.960.0 715
LLPS-Usm-0612Ustilago maydis63.835e-0860.1
LLPS-Dar-2102Danio rerio63.540.0 712
LLPS-Meg-3090Meleagris gallopavo63.210.0 693
LLPS-Icp-3826Ictalurus punctatus61.870.0 689
LLPS-Php-0716Physcomitrella patens61.737e-122 374
LLPS-Lac-2396Latimeria chalumnae61.060.0 671
LLPS-Cae-0503Caenorhabditis elegans59.875e-134 407
LLPS-Met-0815Medicago truncatula59.781e-111 347
LLPS-Orn-0790Oreochromis niloticus59.610.0 669
LLPS-Mel-0152Melampsora laricipopulina58.284e-128 387
LLPS-Xim-1501Xiphophorus maculatus58.230.0 627
LLPS-Gor-0417Gossypium raimondii57.647e-124 379
LLPS-Sob-0339Sorghum bicolor57.548e-124 380
LLPS-Lep-1816Leersia perrieri57.541e-124 383
LLPS-Thc-2366Theobroma cacao57.543e-116 359
LLPS-Zem-2619Zea mays57.411e-123 379
LLPS-Sem-1723Selaginella moellendorffii57.362e-127 383
LLPS-Orbr-0095Oryza brachyantha57.231e-122 377
LLPS-Sei-0223Setaria italica57.231e-123 379
LLPS-Pug-1395Puccinia graminis57.143e-124 381
LLPS-Crn-1226Cryptococcus neoformans57.045e-106 335
LLPS-Brd-2209Brachypodium distachyon56.971e-122 376
LLPS-Hea-2728Helianthus annuus56.971e-118 361
LLPS-Abg-1667Absidia glauca56.98e-108 339
LLPS-Bro-2670Brassica oleracea56.661e-116 360
LLPS-Brr-1684Brassica rapa56.625e-117 361
LLPS-Brn-3326Brassica napus56.629e-117 360
LLPS-Dac-1138Daucus carota56.531e-124 383
LLPS-Ten-0526Tetraodon nigroviridis56.312e-165 483
LLPS-Chr-1489Chlamydomonas reinhardtii56.01e-86 281
LLPS-Art-3056Arabidopsis thaliana55.861e-114 355
LLPS-Phv-2363Phaseolus vulgaris55.493e-111 346
LLPS-Cus-2297Cucumis sativus55.383e-112 349
LLPS-Scc-1646Schizosaccharomyces cryophilus55.371e-120 367
LLPS-Nia-0514Nicotiana attenuata54.777e-119 366
LLPS-Vir-1126Vigna radiata54.632e-109 341
LLPS-Arl-2757Arabidopsis lyrata54.352e-119 367
LLPS-Mae-0616Manihot esculenta54.23e-116 360
LLPS-Scp-1276Schizosaccharomyces pombe54.076e-120 365
LLPS-Org-2030Oryza glaberrima54.061e-123 379
LLPS-Orm-2110Oryza meridionalis54.061e-123 379
LLPS-Orgl-1582Oryza glumaepatula54.063e-122 378
LLPS-Orb-2050Oryza barthii54.065e-122 378
LLPS-Orr-1772Oryza rufipogon53.782e-123 379
LLPS-Ors-0794Oryza sativa53.782e-123 379
LLPS-Ori-2423Oryza indica53.782e-123 379
LLPS-Scj-1325Schizosaccharomyces japonicus53.753e-114 350
LLPS-Tru-1199Triticum urartu53.691e-122 377
LLPS-Tra-2254Triticum aestivum53.691e-122 377
LLPS-Orni-1960Oryza nivara53.55e-123 378
LLPS-Pof-3851Poecilia formosa53.330.0 579
LLPS-Osl-1170Ostreococcus lucimarinus53.028e-107 330
LLPS-Pot-2582Populus trichocarpa52.463e-121 372
LLPS-Tum-1128Tuber melanosporum52.284e-111 343
LLPS-Via-1528Vigna angularis52.152e-109 341
LLPS-Prp-0905Prunus persica51.944e-117 362
LLPS-Phn-0191Phaeosphaeria nodorum51.725e-107 334
LLPS-Mua-2388Musa acuminata51.594e-121 372
LLPS-Nec-1039Neurospora crassa51.524e-103 324
LLPS-Hov-0720Hordeum vulgare51.472e-120 371
LLPS-Lem-0389Leptosphaeria maculans51.411e-106 334
LLPS-Pytr-1199Pyrenophora triticirepentis51.381e-104 328
LLPS-Nef-1606Neosartorya fischeri51.322e-81 266
LLPS-Amt-0969Amborella trichopoda51.13e-123 379
LLPS-Trv-0926Trichoderma virens50.614e-105 329
LLPS-Fus-1002Fusarium solani50.613e-103 323
LLPS-Cis-1189Ciona savignyi50.554e-162 478
LLPS-Coc-1922Corchorus capsularis50.479e-99 313
LLPS-Beb-0442Beauveria bassiana50.462e-103 324
LLPS-Asni-0994Aspergillus niger50.455e-107 333
LLPS-Fuo-0947Fusarium oxysporum50.332e-93 297
LLPS-Sot-1506Solanum tuberosum50.08e-122 374
LLPS-Fuv-1333Fusarium verticillioides50.07e-93 296
LLPS-Orp-0254Oryza punctata49.881e-124 382
LLPS-Viv-1641Vitis vinifera49.884e-113 352
LLPS-Trr-0930Trichoderma reesei49.73e-102 321
LLPS-Zyt-0017Zymoseptoria tritici49.682e-96 306
LLPS-Sol-1032Solanum lycopersicum49.351e-120 370
LLPS-Ast-1210Aspergillus terreus49.256e-105 328
LLPS-Asc-0602Aspergillus clavatus48.815e-103 324
LLPS-Coo-1262Colletotrichum orbiculare48.797e-102 320
LLPS-Blg-0970Blumeria graminis48.737e-108 335
LLPS-Pyt-1500Pyrenophora teres48.634e-105 330
LLPS-Gas-1108Galdieria sulphuraria48.542e-89 288
LLPS-Mao-0611Magnaporthe oryzae48.542e-100 317
LLPS-Cog-0189Colletotrichum gloeosporioides48.483e-99 313
LLPS-Miv-1385Microbotryum violaceum48.042e-112 351
LLPS-Scs-0433Sclerotinia sclerotiorum47.852e-103 325
LLPS-Ved-1547Verticillium dahliae47.768e-95 302
LLPS-Chc-1024Chondrus crispus47.686e-106 332
LLPS-Cogr-0060Colletotrichum graminicola47.582e-100 317
LLPS-Glm-0936Glycine max47.492e-111 347
LLPS-Yal-1111Yarrowia lipolytica47.244e-107 334
LLPS-Asn-0354Aspergillus nidulans47.018e-108 335
LLPS-Asfu-0501Aspergillus fumigatus46.921e-96 307
LLPS-Map-1343Magnaporthe poae46.843e-95 304
LLPS-Cym-0756Cyanidioschyzon merolae46.152e-21 102
LLPS-Dos-0543Dothistroma septosporum45.974e-103 325
LLPS-Gag-1153Gaeumannomyces graminis45.743e-94 302
LLPS-Aso-1316Aspergillus oryzae45.642e-106 332
LLPS-Kop-0880Komagataella pastoris43.285e-88 284
LLPS-Drm-1380Drosophila melanogaster43.269e-149 446
LLPS-Asg-0626Ashbya gossypii41.62e-87 283
LLPS-Sac-0441Saccharomyces cerevisiae41.434e-89 288
LLPS-Put-0118Puccinia triticina25.229e-0859.3