• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-3454
EHD4

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: EH domain containing 4
Gene Name: EHD4
Ensembl Gene: ENSECAG00000017216.2
Ensembl Protein: ENSECAP00000015087.2
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSECAT00000018492.2ENSECAP00000015087.2
UniProtF6SZJ2, F6SZJ2_HORSE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFSWMGRQAG  GRERAGGMDA  VQTVTGGLRS  LYLRKVLPLE  EAYRFHEFHS  PALEDADFEN  60
61    KPMILLVGQY  STGKTTFIRY  LLEQDFPGMR  IGPEPTTDSF  IAVMYGETEG  STPGNALVVD  120
121   PKKPFRKLSR  FGNAFLNRFM  CSQLPNQVLK  SISIIDSPGI  LSGEKQRISR  GYDFCQVLQW  180
181   FAERVDRIIL  LFDAHKLDIS  DEFSEAIKAF  RGQDDKIRVV  LNKADQVDTQ  QLMRVYGALM  240
241   WSLGKVINTP  EVLRVYIGSF  WAQPLQNTDN  RRLFEAEAQD  LFRDIQSLPQ  KAAVRKLNDL  300
301   IKRARLAKVH  AYIISYLKKE  MPSVFGKENK  KRELISRLPE  IYIQLQREYQ  ISAGDFPEVK  360
361   AMQEQLENYD  FTKFHSLKPK  LIEAVDNMLS  NKISSLMSLI  SQEEMSMPTQ  LVQGGAFDGT  420
421   AEGPFNQGYG  EGAKEGADEE  EWVVAKDKPI  YDELFYTLSP  INGKISGVNA  KKEMVTSKLP  480
481   NSVLGKIWKL  ADCDCDGMLD  EEEFALAKHL  IKIKLDGYEL  PNSLPPHLVP  PSHRKSLP  538
Nucleotide CDS Sequence (FASTA)
1     ATGTTCAGCT  GGATGGGGCG  GCAGGCGGGC  GGGCGCGAGC  GCGCAGGCGG  CATGGACGCC  60
61    GTGCAGACCG  TGACGGGCGG  CCTGCGCTCG  CTCTACCTGC  GCAAGGTGCT  GCCGCTGGAG  120
121   GAGGCGTACC  GCTTCCACGA  GTTCCACTCG  CCTGCGCTGG  AGGACGCCGA  CTTCGAAAAC  180
181   AAGCCCATGA  TCCTCCTGGT  GGGCCAGTAC  AGCACAGGCA  AGACCACCTT  CATCAGATAC  240
241   TTATTGGAGC  AAGATTTCCC  CGGCATGAGG  ATTGGTCCAG  AGCCCACCAC  CGATTCCTTC  300
301   ATCGCCGTGA  TGTACGGGGA  GACGGAGGGC  AGCACCCCAG  GGAATGCTCT  AGTCGTGGAC  360
361   CCCAAAAAGC  CGTTTCGAAA  GCTTAGTCGC  TTTGGAAATG  CTTTCCTGAA  TCGATTCATG  420
421   TGCTCCCAGC  TGCCCAATCA  GGTCTTGAAG  AGCATCAGCA  TCATCGACAG  CCCTGGGATC  480
481   CTGTCTGGGG  AGAAGCAGCG  CATCAGCCGA  GGGTACGACT  TCTGCCAGGT  CCTGCAGTGG  540
541   TTCGCTGAAC  GGGTCGACAG  GATCATCTTG  CTCTTCGATG  CTCACAAACT  GGACATCTCG  600
601   GACGAGTTCT  CGGAGGCCAT  CAAGGCCTTC  CGGGGCCAGG  ACGACAAGAT  CCGCGTGGTG  660
661   CTGAACAAGG  CCGACCAGGT  GGACACGCAG  CAGCTGATGC  GGGTCTACGG  GGCCCTCATG  720
721   TGGTCCCTGG  GCAAGGTCAT  CAACACGCCC  GAGGTGCTGC  GCGTCTACAT  TGGCTCCTTC  780
781   TGGGCGCAGC  CCCTGCAGAA  CACTGACAAC  CGCCGGCTCT  TCGAGGCCGA  GGCCCAGGAC  840
841   CTCTTCAGGG  ACATCCAGAG  CCTTCCTCAG  AAGGCGGCGG  TGCGCAAACT  CAATGACCTC  900
901   ATCAAGCGAG  CGAGGCTGGC  CAAGGTACAT  GCCTACATCA  TCAGCTACCT  GAAGAAGGAG  960
961   ATGCCCAGCG  TATTTGGAAA  GGAAAACAAG  AAGAGAGAGC  TCATCAGCAG  GTTGCCAGAA  1020
1021  ATCTACATCC  AGCTGCAGCG  GGAGTACCAG  ATTTCCGCCG  GGGACTTCCC  CGAGGTCAAG  1080
1081  GCCATGCAGG  AACAGCTTGA  GAACTACGAC  TTCACCAAAT  TCCACTCGCT  GAAGCCCAAG  1140
1141  CTGATCGAGG  CCGTGGACAA  CATGCTGAGC  AACAAGATCT  CGTCCCTGAT  GAGCCTCATC  1200
1201  AGCCAGGAGG  AGATGAGCAT  GCCCACGCAG  CTCGTGCAGG  GCGGTGCCTT  CGACGGCACC  1260
1261  GCCGAGGGCC  CCTTCAACCA  AGGCTACGGG  GAGGGCGCCA  AGGAGGGCGC  CGACGAGGAG  1320
1321  GAGTGGGTGG  TGGCCAAAGA  CAAGCCCATC  TACGACGAGC  TCTTCTACAC  CCTGTCGCCC  1380
1381  ATCAATGGCA  AGATATCGGG  CGTCAACGCC  AAGAAGGAGA  TGGTGACCTC  CAAGCTGCCC  1440
1441  AACAGCGTCC  TGGGCAAGAT  CTGGAAGCTG  GCCGACTGTG  ACTGTGATGG  CATGCTGGAC  1500
1501  GAGGAGGAGT  TCGCACTGGC  CAAGCACCTC  ATCAAGATCA  AGCTCGACGG  CTACGAGCTG  1560
1561  CCCAACAGCC  TGCCCCCCCA  CCTCGTGCCT  CCCTCTCACA  GGAAGTCCCT  GCCCTGA  1617

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sus-0839Sus scrofa99.260.01041
LLPS-Ict-2981Ictidomys tridecemlineatus98.880.01041
LLPS-Paa-1299Papio anubis98.70.01037
LLPS-Aim-4102Ailuropoda melanoleuca98.70.01038
LLPS-Dio-1492Dipodomys ordii98.70.0 908
LLPS-Caj-3218Callithrix jacchus98.70.01037
LLPS-Cea-3128Cercocebus atys98.70.01037
LLPS-Maf-4006Macaca fascicularis98.70.01037
LLPS-Chs-1584Chlorocebus sabaeus98.70.01035
LLPS-Mam-1584Macaca mulatta98.70.01037
LLPS-Man-0537Macaca nemestrina98.70.01037
LLPS-Mal-2831Mandrillus leucophaeus98.690.0 902
LLPS-Tut-2501Tursiops truncatus98.510.01036
LLPS-Gog-3527Gorilla gorilla98.510.01035
LLPS-Aon-3334Aotus nancymaae98.510.01036
LLPS-Rhb-3147Rhinopithecus bieti98.510.01035
LLPS-Pat-4233Pan troglodytes98.510.01035
LLPS-Poa-3301Pongo abelii98.330.01033
LLPS-Caf-0219Canis familiaris98.330.01037
LLPS-Hos-1679Homo sapiens98.330.01035
LLPS-Fec-0821Felis catus98.330.01036
LLPS-Mup-2916Mustela putorius furo98.140.01034
LLPS-Ran-3848Rattus norvegicus98.140.01037
LLPS-Mea-3229Mesocricetus auratus98.140.01034
LLPS-Otg-4439Otolemur garnettii98.140.01030
LLPS-Pap-0679Pan paniscus98.140.01030
LLPS-Urm-4007Ursus maritimus97.960.01026
LLPS-Mum-3742Mus musculus97.770.01035
LLPS-Ere-0188Erinaceus europaeus97.40.01027
LLPS-Fud-3785Fukomys damarensis97.270.0 929
LLPS-Orc-1182Oryctolagus cuniculus97.210.01029
LLPS-Cap-2998Cavia porcellus97.170.0 894
LLPS-Myl-3716Myotis lucifugus96.830.01020
LLPS-Loa-3425Loxodonta africana96.520.0 890
LLPS-Mod-3946Monodelphis domestica96.090.01013
LLPS-Ova-3432Ovis aries94.970.0 998
LLPS-Bot-2004Bos taurus94.970.0 999
LLPS-Ora-0972Ornithorhynchus anatinus93.260.0 853
LLPS-Meg-1345Meleagris gallopavo92.590.0 853
LLPS-Gaga-0258Gallus gallus91.080.0 967
LLPS-Tag-0396Taeniopygia guttata90.650.0 957
LLPS-Pes-2192Pelodiscus sinensis90.460.0 840
LLPS-Anp-0568Anas platyrhynchos90.330.0 962
LLPS-Nol-1066Nomascus leucogenys90.170.0 918
LLPS-Xet-2328Xenopus tropicalis84.860.0 918
LLPS-Lac-1080Latimeria chalumnae81.750.0 891
LLPS-Asm-1158Astyanax mexicanus80.040.0 869
LLPS-Leo-2467Lepisosteus oculatus79.890.0 872
LLPS-Icp-4109Ictalurus punctatus78.920.0 853
LLPS-Scf-1661Scleropages formosus78.030.0 774
LLPS-Orn-1854Oreochromis niloticus77.990.0 850
LLPS-Xim-2763Xiphophorus maculatus77.610.0 851
LLPS-Pof-3957Poecilia formosa77.610.0 850
LLPS-Ten-2641Tetraodon nigroviridis77.550.0 843
LLPS-Tar-0067Takifugu rubripes77.430.0 848
LLPS-Orl-4056Oryzias latipes77.240.0 844
LLPS-Scm-1056Scophthalmus maximus76.820.0 840
LLPS-Gaa-1798Gasterosteus aculeatus75.830.0 801
LLPS-Dar-2625Danio rerio75.290.0 791
LLPS-Sah-2835Sarcophilus harrisii74.950.0 795
LLPS-Cas-1197Carlito syrichta74.950.0 796
LLPS-Fia-0924Ficedula albicollis74.580.0 796
LLPS-Anc-1480Anolis carolinensis72.90.0 790
LLPS-Cis-2069Ciona savignyi64.330.0 691
LLPS-Cii-0223Ciona intestinalis63.380.0 690
LLPS-Mae-0420Manihot esculenta57.075e-155 461
LLPS-Gor-2372Gossypium raimondii56.282e-148 444
LLPS-Arl-1091Arabidopsis lyrata56.022e-151 452
LLPS-Nia-2183Nicotiana attenuata55.911e-145 437
LLPS-Orp-1977Oryza punctata55.733e-153 457
LLPS-Art-1442Arabidopsis thaliana55.649e-151 451
LLPS-Sol-1360Solanum lycopersicum55.52e-138 430
LLPS-Lep-1725Leersia perrieri55.476e-153 457
LLPS-Orbr-0494Oryza brachyantha55.475e-153 456
LLPS-Coc-1537Corchorus capsularis55.248e-149 446
LLPS-Orgl-0630Oryza glumaepatula55.211e-151 455
LLPS-Orni-2397Oryza nivara55.211e-151 455
LLPS-Ori-0921Oryza indica55.211e-152 455
LLPS-Orr-2093Oryza rufipogon55.212e-151 454
LLPS-Orm-1854Oryza meridionalis55.211e-151 454
LLPS-Viv-2269Vitis vinifera55.216e-151 451
LLPS-Ors-1559Oryza sativa55.211e-152 455
LLPS-Met-1472Medicago truncatula54.973e-150 449
LLPS-Prp-1265Prunus persica54.971e-150 450
LLPS-Orb-0239Oryza barthii54.951e-150 452
LLPS-Org-2111Oryza glaberrima54.958e-152 453
LLPS-Phv-0838Phaseolus vulgaris54.952e-151 452
LLPS-Brn-0194Brassica napus54.862e-149 447
LLPS-Bro-1762Brassica oleracea54.868e-149 447
LLPS-Brr-1741Brassica rapa54.862e-149 447
LLPS-Glm-2778Glycine max54.696e-150 448
LLPS-Vir-1378Vigna radiata53.891e-121 368
LLPS-Sem-2317Selaginella moellendorffii53.793e-143 431
LLPS-Tra-2736Triticum aestivum53.653e-147 441
LLPS-Thc-2124Theobroma cacao52.86e-145 437
LLPS-Mua-2380Musa acuminata51.927e-143 433
LLPS-Via-1825Vigna angularis44.623e-107 334