• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-2712
ASL

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Argininosuccinate lyase
Gene Name: ASL
Ensembl Gene: ENSECAG00000012730.2
Ensembl Protein: ENSECAP00000011055.2
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNDPACLFTL  FISCARQAWP  DVFVSTSSPS  LQCPVLGPLP  PRHHPHCPHS  CPGAARPKAP  60
61    LETAPPRAGV  GGRRQRPPRR  PPGIGGAAAR  RRGQSQAAAD  ALRARKAPPG  GWRETTARRA  120
121   VVSVPRRDER  DRGTQGAPRT  VARWALPTSA  SPWAALRPAP  CPARSPCLPG  AGKVVSPILS  180
181   SRRGGPRLPE  DEEPPNMASE  SGKLWGGRFV  GTVDPIMEKF  NSSITYDRHL  WEVDVQGSKA  240
241   YSRGLEKAGL  LTKAEVDQIH  HGLDKVAEEW  AQDTFKLNPN  DEDIHTANER  RLKELIGETA  300
301   GKLHTGRSRN  DQVVTDLRLW  MRQNCWTLSA  LLWGLIRTMV  DRAEAERDIL  FPGYTHLQRA  360
361   QPIRWSHWIL  SHAVALTRDS  ERLLEVQKRI  NVLPLGSGAI  AGNPLGVDRE  LLRAELNFGA  420
421   ITLNSMDATS  ERDFVAEFLF  WASLCMTHLS  RMAEDLILYS  TKEFSFVQLS  DAYSTGSSLM  480
481   PQKKNPDSLE  LIRSKAGRVF  GRCAGLLMTL  KGLPSTYNKD  LQEDKEAVFE  VSDTMSAVLQ  540
541   VATGIISTLQ  IHPENMARAL  SPDMLATDLA  YYLVRKGMPF  RQAHEASGKA  VFMAETKGVA  600
601   LNQLSLQELQ  TISPLFSGDV  SHVWDYGHSV  EQYAALGGTA  RSSVDWQISQ  VRALLRAQQA  660
Nucleotide CDS Sequence (FASTA)
1     ATGGCATCAG  AGAGCGGGAA  GCTGTGGGGT  GGCCGGTTTG  TGGGCACGGT  GGACCCCATC  60
61    ATGGAGAAGT  TCAACTCATC  CATCACCTAT  GACCGGCACC  TGTGGGAGGT  GGACGTGCAG  120
121   GGCAGCAAGG  CCTACAGCCG  GGGCCTGGAG  AAGGCGGGCC  TCCTCACCAA  GGCTGAGGTG  180
181   GACCAGATAC  ACCATGGCCT  AGACAAGGTG  GCTGAGGAGT  GGGCCCAGGA  CACCTTCAAA  240
241   CTAAACCCCA  ATGATGAGGA  CATCCACACG  GCCAATGAGC  GGCGTCTGAA  GGAGCTCATC  300
301   GGAGAAACCG  CAGGGAAGCT  GCATACAGGA  CGAAGTCGAA  ACGACCAGGT  GGTCACAGAC  360
361   CTCAGGTTGT  GGATGCGGCA  GAACTGCTGG  ACGCTCTCTG  CCCTCCTCTG  GGGGCTCATC  420
421   AGAACGATGG  TGGATCGGGC  AGAGGCGGAA  CGTGACATCC  TCTTCCCAGG  GTACACACAC  480
481   CTACAGAGGG  CTCAGCCCAT  CCGCTGGAGC  CATTGGATCC  TGAGCCATGC  CGTGGCACTG  540
541   ACCAGAGACT  CTGAGAGGCT  GCTGGAGGTG  CAGAAGCGGA  TCAACGTCCT  GCCCCTGGGG  600
601   AGCGGGGCCA  TTGCAGGCAA  TCCTCTGGGT  GTGGACCGGG  AGCTGCTCCG  AGCAGAACTG  660
661   AACTTTGGGG  CTATCACTCT  CAACAGCATG  GATGCTACCA  GTGAGCGAGA  CTTTGTGGCT  720
721   GAGTTCCTGT  TCTGGGCTTC  ACTGTGCATG  ACCCATCTTA  GCAGGATGGC  TGAGGATCTC  780
781   ATCCTCTACA  GCACCAAGGA  ATTCAGCTTT  GTGCAGCTCT  CAGATGCGTA  CAGCACTGGA  840
841   AGCAGCCTGA  TGCCCCAGAA  GAAAAACCCA  GATAGCCTGG  AGCTGATCCG  GAGCAAGGCG  900
901   GGGCGAGTGT  TTGGGCGGTG  TGCTGGGCTC  CTGATGACAC  TGAAAGGACT  TCCGAGCACC  960
961   TACAACAAGG  ACTTACAGGA  GGACAAGGAA  GCCGTGTTTG  AAGTGTCAGA  CACCATGAGC  1020
1021  GCCGTCCTCC  AAGTGGCCAC  TGGTATCATC  TCTACACTGC  AGATTCATCC  TGAGAACATG  1080
1081  GCACGGGCTC  TTAGTCCTGA  CATGCTGGCC  ACTGACCTTG  CCTACTACCT  GGTCCGCAAA  1140
1141  GGGATGCCAT  TCCGCCAGGC  CCACGAGGCC  TCTGGCAAAG  CCGTGTTCAT  GGCTGAGACC  1200
1201  AAGGGGGTTG  CCCTTAACCA  GCTGTCGCTG  CAGGAGCTAC  AGACCATCAG  CCCCCTGTTC  1260
1261  TCGGGTGACG  TGAGCCACGT  TTGGGACTAC  GGGCACAGCG  TTGAGCAGTA  TGCTGCCCTG  1320
1321  GGTGGCACGG  CGCGCTCCAG  TGTTGACTGG  CAGATCAGCC  AGGGGAAGCT  GGCATAG  1377

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Caj-4590Callithrix jacchus98.973e-58 199
LLPS-Fec-4079Felis catus95.910.0 918
LLPS-Ova-2240Ovis aries95.880.0 896
LLPS-Cas-2899Carlito syrichta95.870.0 907
LLPS-Mup-0187Mustela putorius furo95.690.0 915
LLPS-Urm-1876Ursus maritimus95.470.0 911
LLPS-Pap-3923Pan paniscus95.260.0 908
LLPS-Pat-3790Pan troglodytes95.260.0 908
LLPS-Poa-2403Pongo abelii95.050.0 868
LLPS-Sus-1814Sus scrofa95.040.0 908
LLPS-Myl-2017Myotis lucifugus95.040.0 906
LLPS-Aim-4241Ailuropoda melanoleuca95.020.0 897
LLPS-Gog-0561Gorilla gorilla94.830.0 904
LLPS-Hos-4204Homo sapiens94.830.0 904
LLPS-Rhb-4141Rhinopithecus bieti94.830.0 903
LLPS-Paa-2381Papio anubis94.610.0 903
LLPS-Ict-4634Ictidomys tridecemlineatus94.610.0 907
LLPS-Otg-4167Otolemur garnettii94.580.0 894
LLPS-Dio-4066Dipodomys ordii94.40.0 902
LLPS-Man-1480Macaca nemestrina94.40.0 900
LLPS-Chs-1174Chlorocebus sabaeus94.180.0 900
LLPS-Cea-4571Cercocebus atys93.710.0 887
LLPS-Mum-3149Mus musculus93.30.0 887
LLPS-Caf-3252Canis familiaris93.010.0 877
LLPS-Mea-0651Mesocricetus auratus92.460.0 885
LLPS-Loa-2526Loxodonta africana92.140.0 890
LLPS-Cap-4479Cavia porcellus91.360.0 874
LLPS-Tut-0062Tursiops truncatus91.30.0 946
LLPS-Nol-2130Nomascus leucogenys90.780.0 546
LLPS-Bot-0758Bos taurus90.540.0 904
LLPS-Fud-4085Fukomys damarensis90.340.0 708
LLPS-Ran-3299Rattus norvegicus89.350.0 845
LLPS-Mam-0193Macaca mulatta87.740.0 808
LLPS-Sah-2662Sarcophilus harrisii85.430.0 821
LLPS-Orc-3825Oryctolagus cuniculus85.310.0 895
LLPS-Maf-0358Macaca fascicularis85.250.0 781
LLPS-Mod-0314Monodelphis domestica79.190.0 811
LLPS-Mal-4451Mandrillus leucophaeus76.940.0 701
LLPS-Pes-1280Pelodiscus sinensis74.950.0 737
LLPS-Asm-3538Astyanax mexicanus72.330.0 702
LLPS-Icp-3047Ictalurus punctatus71.80.0 704
LLPS-Gaa-3167Gasterosteus aculeatus71.770.0 692
LLPS-Orl-0408Oryzias latipes71.520.0 693
LLPS-Ten-2384Tetraodon nigroviridis70.870.0 685
LLPS-Scm-1220Scophthalmus maximus70.780.0 691
LLPS-Tag-1248Taeniopygia guttata70.520.0 686
LLPS-Scf-0916Scleropages formosus70.350.0 688
LLPS-Xim-3731Xiphophorus maculatus70.220.0 683
LLPS-Orn-3720Oreochromis niloticus70.150.0 684
LLPS-Tar-1831Takifugu rubripes69.930.0 674
LLPS-Dar-3023Danio rerio69.70.0 692
LLPS-Meg-2127Meleagris gallopavo69.410.0 681
LLPS-Pof-3191Poecilia formosa68.760.0 672
LLPS-Gaga-3852Gallus gallus68.550.0 671
LLPS-Fia-2406Ficedula albicollis68.260.0 672
LLPS-Ora-2565Ornithorhynchus anatinus64.562e-126 383
LLPS-Xet-2609Xenopus tropicalis64.010.0 610
LLPS-Anp-1796Anas platyrhynchos60.30.0 573
LLPS-Cii-2083Ciona intestinalis58.70.0 570
LLPS-Mel-0459Melampsora laricipopulina58.120.0 570
LLPS-Abg-1538Absidia glauca57.950.0 560
LLPS-Scj-0225Schizosaccharomyces japonicus57.930.0 573
LLPS-Usm-0956Ustilago maydis57.270.0 548
LLPS-Scc-1204Schizosaccharomyces cryophilus57.170.0 567
LLPS-Tum-0837Tuber melanosporum57.114e-175 514
LLPS-Spr-1256Sporisorium reilianum57.020.0 546
LLPS-Pug-1472Puccinia graminis56.580.0 555
LLPS-Scp-0498Schizosaccharomyces pombe56.520.0 567
LLPS-Crn-0396Cryptococcus neoformans55.970.0 536
LLPS-Ved-0345Verticillium dahliae55.636e-173 509
LLPS-Chr-1118Chlamydomonas reinhardtii55.587e-176 518
LLPS-Aso-0064Aspergillus oryzae55.415e-178 522
LLPS-Asf-0938Aspergillus flavus55.415e-178 522
LLPS-Leo-2265Lepisosteus oculatus55.36e-167 494
LLPS-Blg-1480Blumeria graminis55.243e-175 515
LLPS-Dos-1350Dothistroma septosporum55.02e-180 528
LLPS-Zyt-0524Zymoseptoria tritici54.765e-180 527
LLPS-Ast-1028Aspergillus terreus54.755e-173 509
LLPS-Nef-1287Neosartorya fischeri54.752e-176 518
LLPS-Pytr-0608Pyrenophora triticirepentis54.531e-174 513
LLPS-Sac-0564Saccharomyces cerevisiae54.331e-177 521
LLPS-Asfu-0886Aspergillus fumigatus54.322e-168 496
LLPS-Pyt-1620Pyrenophora teres54.318e-174 511
LLPS-Asn-0554Aspergillus nidulans54.31e-174 513
LLPS-Osl-0916Ostreococcus lucimarinus54.34e-168 496
LLPS-Trr-0129Trichoderma reesei54.251e-177 521
LLPS-Trv-0453Trichoderma virens54.253e-177 520
LLPS-Nec-1428Neurospora crassa54.193e-174 512
LLPS-Yal-0635Yarrowia lipolytica54.051e-178 523
LLPS-Asg-0390Ashbya gossypii54.04e-174 512
LLPS-Phn-1485Phaeosphaeria nodorum53.963e-172 507
LLPS-Lem-0590Leptosphaeria maculans53.882e-171 505
LLPS-Asc-1434Aspergillus clavatus53.869e-175 513
LLPS-Put-0082Puccinia triticina53.831e-177 521
LLPS-Kop-1353Komagataella pastoris53.71e-177 521
LLPS-Cog-0344Colletotrichum gloeosporioides53.639e-173 508
LLPS-Asni-1166Aspergillus niger53.583e-172 507
LLPS-Mao-0109Magnaporthe oryzae53.191e-173 511
LLPS-Fus-0923Fusarium solani53.163e-174 512
LLPS-Cogr-0484Colletotrichum graminicola52.721e-170 503
LLPS-Drm-0636Drosophila melanogaster52.654e-166 492
LLPS-Fuv-1392Fusarium verticillioides52.544e-175 514
LLPS-Coo-1420Colletotrichum orbiculare52.386e-86 291
LLPS-Miv-1113Microbotryum violaceum52.191e-166 493
LLPS-Beb-1341Beauveria bassiana52.167e-173 509
LLPS-Fuo-0800Fusarium oxysporum51.832e-162 482
LLPS-Gag-0116Gaeumannomyces graminis51.612e-166 492
LLPS-Map-1255Magnaporthe poae51.382e-81 265
LLPS-Scs-1113Sclerotinia sclerotiorum49.124e-143 431
LLPS-Ori-1739Oryza indica44.221e-106 353
LLPS-Cym-0737Cyanidioschyzon merolae43.897e-118 367
LLPS-Nia-1527Nicotiana attenuata43.362e-54 192
LLPS-Prp-2488Prunus persica43.337e-119 372
LLPS-Sem-2397Selaginella moellendorffii43.181e-114 359
LLPS-Coc-1044Corchorus capsularis42.953e-111 352
LLPS-Thc-0415Theobroma cacao42.732e-116 365
LLPS-Dac-1152Daucus carota42.515e-115 360
LLPS-Brr-0310Brassica rapa42.512e-114 372
LLPS-Sei-1294Setaria italica42.424e-113 357
LLPS-Pot-0911Populus trichocarpa42.383e-116 365
LLPS-Bro-2772Brassica oleracea42.293e-118 370
LLPS-Mua-1725Musa acuminata42.262e-116 364
LLPS-Amt-2256Amborella trichopoda42.194e-116 365
LLPS-Sob-0213Sorghum bicolor42.161e-113 358
LLPS-Orb-2012Oryza barthii42.071e-111 362
LLPS-Brn-2443Brassica napus42.073e-117 367
LLPS-Orgl-1920Oryza glumaepatula42.079e-114 358
LLPS-Php-0806Physcomitrella patens42.061e-112 356
LLPS-Gor-2112Gossypium raimondii42.062e-116 366
LLPS-Viv-2179Vitis vinifera42.019e-119 370
LLPS-Lep-1604Leersia perrieri41.859e-110 359
LLPS-Met-2572Medicago truncatula41.789e-115 361
LLPS-Sol-2115Solanum lycopersicum41.748e-117 367
LLPS-Orp-0774Oryza punctata41.634e-110 351
LLPS-Glm-2833Glycine max41.333e-114 360
LLPS-Brd-0460Brachypodium distachyon41.281e-111 353
LLPS-Art-2777Arabidopsis thaliana41.287e-116 364
LLPS-Gas-1152Galdieria sulphuraria41.261e-118 369
LLPS-Phv-1339Phaseolus vulgaris41.264e-113 357
LLPS-Vir-0271Vigna radiata41.251e-77 261
LLPS-Via-1213Vigna angularis41.241e-113 358
LLPS-Tra-0463Triticum aestivum41.192e-113 357
LLPS-Mae-1275Manihot esculenta41.051e-117 369
LLPS-Hov-0867Hordeum vulgare40.896e-100 328
LLPS-Ors-1130Oryza sativa40.895e-101 332
LLPS-Arl-0931Arabidopsis lyrata40.812e-110 350
LLPS-Orr-0379Oryza rufipogon40.434e-114 359
LLPS-Org-1803Oryza glaberrima40.434e-114 359
LLPS-Sot-1890Solanum tuberosum40.424e-112 355
LLPS-Chc-1021Chondrus crispus40.362e-113 355
LLPS-Cus-0410Cucumis sativus40.082e-117 368
LLPS-Orbr-1506Oryza brachyantha40.088e-113 356
LLPS-Orni-1294Oryza nivara39.591e-111 363
LLPS-Zem-1571Zea mays38.858e-103 340
LLPS-Tru-1702Triticum urartu37.679e-94 304
LLPS-Hea-1377Helianthus annuus36.076e-67 240