• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-2635
GMPPB

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: GDP-mannose pyrophosphorylase B
Gene Name: GMPPB
Ensembl Gene: ENSECAG00000019354.2
Ensembl Protein: ENSECAP00000016915.2
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSECAT00000020595.2ENSECAP00000016915.2
UniProtF6VTV5, F6VTV5_HORSE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLGRRRPCHV  HASRLARPDS  RHCRPEFGTS  RPPSGVAYWF  VAAWNPALGK  TERTRQRQSW  60
61    SVWQVKGAGP  GTTAGVRGGS  RPGGPQTPRS  PGLTLQPPAG  AMKALILVGG  YGTRLRPLTL  120
121   SIPKPLVDFC  NKPILLHQVE  ALAAAGVDHV  ILAVSYMSQV  LEKEMKAQEQ  RLGIRISLSH  180
181   EEEPLGTAGP  LALARDLLSE  TADPFFVLNS  DVICDFPFQA  MVQFHQHHGQ  EGSILVTKVE  240
241   EPSKYGVVVC  EADTGRIHRF  VEKPQVFVSN  KINAGMYILS  PAVLRRIQLQ  PTSIEKEIFP  300
301   VMAKEGQLYA  MELQGFWMDI  GQPKDFLTGM  CLFLQSLRQK  QPEQLCSGPG  IVGNVLVDPS  360
361   ASIGQNCSIG  PNVSLGPGVV  VEDGVCIRRC  TVLRDAHIRS  HSWLESCIVG  WRCRVGQWVR  420
421   MENVTVLGED  VIVNDELYLN  GASVLPHKSI  GESVPEPRII  M  461
Nucleotide CDS Sequence (FASTA)
1     ATGCTCGGAC  GCCGGCGGCC  GTGCCACGTA  CACGCCAGCC  GATTGGCCCG  CCCAGATTCA  60
61    CGTCACTGTC  GGCCTGAGTT  CGGGACCAGC  CGCCCTCCGT  CCGGCGTCGC  GTACTGGTTT  120
121   GTGGCGGCCT  GGAATCCGGC  GTTAGGGAAG  ACTGAGCGGA  CACGGCAGAG  ACAGAGCTGG  180
181   TCAGTCTGGC  AGGTGAAAGG  CGCGGGGCCG  GGCACGACTG  CGGGAGTGCG  CGGCGGGAGT  240
241   CGGCCAGGCG  GGCCGCAGAC  ACCTCGGAGC  CCGGGACTCA  CTCTCCAGCC  GCCCGCCGGC  300
301   GCGATGAAGG  CACTGATCTT  GGTGGGCGGC  TATGGGACGC  GCCTGCGGCC  GCTGACGTTA  360
361   AGCATCCCGA  AGCCACTGGT  GGACTTCTGC  AATAAGCCCA  TCTTGCTGCA  CCAAGTGGAG  420
421   GCGCTGGCCG  CGGCCGGCGT  GGACCACGTG  ATTCTGGCCG  TAAGCTACAT  GTCTCAGGTG  480
481   CTGGAGAAGG  AAATGAAGGC  GCAGGAGCAA  AGGCTAGGAA  TCCGAATCTC  CTTGTCCCAT  540
541   GAAGAGGAGC  CTTTGGGGAC  AGCTGGGCCC  CTGGCACTAG  CTCGTGACCT  GCTTTCTGAG  600
601   ACTGCAGACC  CTTTCTTCGT  CCTCAATAGT  GATGTGATCT  GTGATTTCCC  CTTCCAAGCC  660
661   ATGGTGCAGT  TCCACCAGCA  CCACGGCCAG  GAAGGCTCCA  TCCTGGTGAC  CAAAGTGGAG  720
721   GAACCTTCTA  AGTACGGTGT  GGTGGTGTGT  GAGGCTGATA  CAGGCCGCAT  TCACCGGTTT  780
781   GTGGAGAAGC  CGCAGGTGTT  TGTGTCCAAC  AAGATCAATG  CAGGCATGTA  CATCCTGAGC  840
841   CCTGCAGTGC  TGCGGCGCAT  CCAGCTGCAG  CCTACGTCCA  TTGAGAAGGA  GATCTTCCCT  900
901   GTCATGGCCA  AGGAAGGACA  GCTATATGCC  ATGGAGCTGC  AGGGCTTCTG  GATGGACATT  960
961   GGGCAGCCCA  AGGATTTCCT  CACTGGAATG  TGCCTCTTCC  TACAGTCACT  GCGACAGAAG  1020
1021  CAGCCTGAGC  AACTGTGCTC  AGGCCCTGGC  ATTGTGGGCA  ACGTGCTGGT  GGACCCAAGT  1080
1081  GCCAGCATTG  GCCAGAACTG  CAGCATTGGC  CCCAACGTGA  GCCTGGGTCC  TGGTGTGGTG  1140
1141  GTGGAGGATG  GTGTGTGTAT  CCGACGGTGC  ACAGTGCTGC  GAGACGCCCA  CATTCGCTCC  1200
1201  CACTCCTGGC  TTGAGTCCTG  CATTGTGGGT  TGGCGCTGCC  GTGTGGGCCA  GTGGGTGCGC  1260
1261  ATGGAGAATG  TGACAGTGCT  GGGTGAGGAC  GTCATAGTTA  ACGACGAGCT  CTACCTCAAC  1320
1321  GGGGCCAGTG  TCCTGCCCCA  CAAGTCTATT  GGCGAGTCGG  TGCCGGAGCC  TCGCATCATC  1380
1381  ATGTGA  1386

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fec-0312Felis catus98.610.0 727
LLPS-Urm-2445Ursus maritimus98.360.0 618
LLPS-Otg-3346Otolemur garnettii97.780.0 723
LLPS-Poa-2292Pongo abelii97.780.0 723
LLPS-Nol-1325Nomascus leucogenys97.780.0 723
LLPS-Ict-3611Ictidomys tridecemlineatus97.780.0 724
LLPS-Mup-3250Mustela putorius furo97.780.0 717
LLPS-Cas-0544Carlito syrichta97.50.0 720
LLPS-Mal-2370Mandrillus leucophaeus97.50.0 719
LLPS-Ova-0905Ovis aries97.50.0 721
LLPS-Orc-0543Oryctolagus cuniculus97.220.0 721
LLPS-Rhb-4206Rhinopithecus bieti97.220.0 717
LLPS-Mum-4576Mus musculus97.220.0 717
LLPS-Fud-3332Fukomys damarensis96.940.0 715
LLPS-Dio-1390Dipodomys ordii96.940.0 719
LLPS-Bot-1856Bos taurus96.940.0 718
LLPS-Ran-0083Rattus norvegicus96.940.0 716
LLPS-Cap-0464Cavia porcellus96.390.0 709
LLPS-Mea-3274Mesocricetus auratus96.390.0 715
LLPS-Tut-1269Tursiops truncatus92.210.0 710
LLPS-Aim-0315Ailuropoda melanoleuca91.730.0 713
LLPS-Caf-2999Canis familiaris91.470.0 710
LLPS-Caj-0603Callithrix jacchus91.210.0 707
LLPS-Pat-1523Pan troglodytes90.960.0 706
LLPS-Pap-2042Pan paniscus90.960.0 706
LLPS-Aon-4166Aotus nancymaae90.960.0 705
LLPS-Gog-0501Gorilla gorilla90.960.0 706
LLPS-Hos-4237Homo sapiens90.70.0 704
LLPS-Chs-1004Chlorocebus sabaeus90.70.0 702
LLPS-Paa-2195Papio anubis90.70.0 702
LLPS-Man-0814Macaca nemestrina90.440.0 699
LLPS-Mam-0562Macaca mulatta90.440.0 699
LLPS-Cea-1222Cercocebus atys90.440.0 700
LLPS-Maf-4219Macaca fascicularis90.440.0 699
LLPS-Mod-2074Monodelphis domestica88.590.0 662
LLPS-Loa-1597Loxodonta africana88.080.0 646
LLPS-Anc-2552Anolis carolinensis84.720.0 634
LLPS-Anp-2243Anas platyrhynchos84.487e-102 308
LLPS-Ere-0591Erinaceus europaeus83.731e-113 340
LLPS-Dar-0929Danio rerio82.780.0 634
LLPS-Lac-2636Latimeria chalumnae82.780.0 634
LLPS-Asm-0425Astyanax mexicanus82.780.0 631
LLPS-Scm-2282Scophthalmus maximus82.220.0 627
LLPS-Leo-1644Lepisosteus oculatus82.220.0 627
LLPS-Pes-2446Pelodiscus sinensis82.096e-119 354
LLPS-Orn-2303Oreochromis niloticus81.940.0 628
LLPS-Xet-0551Xenopus tropicalis81.940.0 624
LLPS-Icp-1434Ictalurus punctatus81.670.0 626
LLPS-Gaa-0958Gasterosteus aculeatus81.390.0 621
LLPS-Scf-1120Scleropages formosus81.390.0 620
LLPS-Tag-1082Taeniopygia guttata81.039e-175 499
LLPS-Fia-0207Ficedula albicollis80.770.0 532
LLPS-Pof-0465Poecilia formosa80.560.0 616
LLPS-Gaga-2596Gallus gallus80.280.0 605
LLPS-Xim-1069Xiphophorus maculatus80.280.0 612
LLPS-Ten-3393Tetraodon nigroviridis79.780.0 597
LLPS-Orl-2257Oryzias latipes77.740.0 535
LLPS-Cis-0710Ciona savignyi70.280.0 533
LLPS-Drm-1676Drosophila melanogaster69.640.0 535
LLPS-Cii-1035Ciona intestinalis68.232e-90 280
LLPS-Hea-0918Helianthus annuus63.432e-165 481
LLPS-Cae-0104Caenorhabditis elegans63.115e-162 470
LLPS-Sem-1590Selaginella moellendorffii62.337e-167 482
LLPS-Mae-0996Manihot esculenta62.051e-164 476
LLPS-Gor-1336Gossypium raimondii61.52e-163 473
LLPS-Art-0554Arabidopsis thaliana61.53e-163 473
LLPS-Nia-0021Nicotiana attenuata61.51e-163 473
LLPS-Met-0384Medicago truncatula61.51e-163 474
LLPS-Gas-0127Galdieria sulphuraria61.399e-166 479
LLPS-Dos-0820Dothistroma septosporum61.263e-160 465
LLPS-Zyt-0618Zymoseptoria tritici61.263e-162 470
LLPS-Coc-0968Corchorus capsularis61.224e-162 469
LLPS-Sot-0649Solanum tuberosum61.227e-162 469
LLPS-Tra-0041Triticum aestivum61.221e-160 466
LLPS-Thc-1433Theobroma cacao61.054e-160 465
LLPS-Amt-2064Amborella trichopoda60.949e-159 461
LLPS-Zem-1449Zea mays60.946e-161 467
LLPS-Brn-2218Brassica napus60.949e-162 469
LLPS-Sol-1130Solanum lycopersicum60.941e-161 469
LLPS-Arl-2012Arabidopsis lyrata60.942e-162 470
LLPS-Cus-1423Cucumis sativus60.948e-162 469
LLPS-Brd-1537Brachypodium distachyon60.941e-160 466
LLPS-Ved-0433Verticillium dahliae60.712e-164 476
LLPS-Pot-0798Populus trichocarpa60.663e-161 468
LLPS-Ors-0788Oryza sativa60.665e-160 464
LLPS-Brr-2667Brassica rapa60.665e-161 467
LLPS-Sob-0268Sorghum bicolor60.662e-159 463
LLPS-Orbr-1557Oryza brachyantha60.662e-160 465
LLPS-Orr-1172Oryza rufipogon60.665e-160 464
LLPS-Orm-0535Oryza meridionalis60.664e-160 465
LLPS-Org-1456Oryza glaberrima60.664e-160 465
LLPS-Bro-0053Brassica oleracea60.667e-161 466
LLPS-Orb-2015Oryza barthii60.664e-160 465
LLPS-Ori-0788Oryza indica60.666e-160 464
LLPS-Glm-1187Glycine max60.662e-163 473
LLPS-Orni-1941Oryza nivara60.664e-160 465
LLPS-Via-1298Vigna angularis60.667e-162 469
LLPS-Orgl-0135Oryza glumaepatula60.664e-160 465
LLPS-Vir-2075Vigna radiata60.665e-162 469
LLPS-Sei-0955Setaria italica60.663e-159 462
LLPS-Tum-0443Tuber melanosporum60.51e-156 456
LLPS-Gag-0160Gaeumannomyces graminis60.442e-159 463
LLPS-Map-1393Magnaporthe poae60.449e-160 464
LLPS-Mua-0015Musa acuminata60.221e-157 462
LLPS-Scj-0623Schizosaccharomyces japonicus60.226e-164 474
LLPS-Prp-0105Prunus persica60.112e-162 470
LLPS-Asc-0936Aspergillus clavatus59.941e-155 454
LLPS-Scc-0782Schizosaccharomyces cryophilus59.676e-165 477
LLPS-Coo-0430Colletotrichum orbiculare59.624e-159 462
LLPS-Nec-0837Neurospora crassa59.625e-159 462
LLPS-Dac-1424Daucus carota59.571e-140 414
LLPS-Orp-0152Oryza punctata59.563e-158 460
LLPS-Cog-0102Colletotrichum gloeosporioides59.56e-158 459
LLPS-Scp-0476Schizosaccharomyces pombe59.392e-162 471
LLPS-Scs-0258Sclerotinia sclerotiorum59.331e-105 322
LLPS-Php-1959Physcomitrella patens59.286e-158 459
LLPS-Nef-1418Neosartorya fischeri59.16e-156 454
LLPS-Trr-1133Trichoderma reesei59.075e-158 459
LLPS-Asni-1250Aspergillus niger59.075e-159 462
LLPS-Blg-0706Blumeria graminis59.071e-158 461
LLPS-Aso-0627Aspergillus oryzae59.075e-158 459
LLPS-Asf-0597Aspergillus flavus59.075e-158 459
LLPS-Hov-1505Hordeum vulgare59.059e-143 421
LLPS-Phv-0373Phaseolus vulgaris59.03e-159 462
LLPS-Asn-0076Aspergillus nidulans58.797e-160 464
LLPS-Lem-0693Leptosphaeria maculans58.796e-161 467
LLPS-Asfu-0288Aspergillus fumigatus58.713e-154 452
LLPS-Crn-0476Cryptococcus neoformans58.631e-150 440
LLPS-Fuo-1121Fusarium oxysporum58.525e-156 454
LLPS-Fuv-0276Fusarium verticillioides58.525e-156 454
LLPS-Chr-1136Chlamydomonas reinhardtii58.457e-151 441
LLPS-Mao-0402Magnaporthe oryzae58.242e-156 455
LLPS-Cogr-1303Colletotrichum graminicola58.211e-146 430
LLPS-Fus-0670Fusarium solani57.974e-154 449
LLPS-Trv-0442Trichoderma virens57.972e-154 451
LLPS-Mel-0977Melampsora laricipopulina57.975e-153 446
LLPS-Abg-0543Absidia glauca57.817e-157 456
LLPS-Lep-0542Leersia perrieri57.729e-134 400
LLPS-Sac-0980Saccharomyces cerevisiae57.623e-155 452
LLPS-Put-0182Puccinia triticina57.429e-153 446
LLPS-Miv-0833Microbotryum violaceum57.146e-147 431
LLPS-Kop-0914Komagataella pastoris57.143e-153 447
LLPS-Ast-0979Aspergillus terreus56.925e-135 399
LLPS-Pug-0075Puccinia graminis56.796e-152 444
LLPS-Asg-0350Ashbya gossypii56.795e-151 441
LLPS-Yal-0846Yarrowia lipolytica56.476e-150 439
LLPS-Pyt-0346Pyrenophora teres55.722e-155 464
LLPS-Cym-0349Cyanidioschyzon merolae55.562e-147 432
LLPS-Pytr-0916Pyrenophora triticirepentis54.48e-142 417
LLPS-Tru-1495Triticum urartu53.883e-151 444
LLPS-Chc-0148Chondrus crispus53.334e-137 406
LLPS-Myl-1079Myotis lucifugus26.818e-0652.4
LLPS-Sah-4052Sarcophilus harrisii26.432e-0757.4