LLPS-Eqc-2457
OTUD4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | OTU deubiquitinase 4 |
| Gene Name: | OTUD4 |
| Ensembl Gene: | ENSECAG00000023403.2 |
| Ensembl Protein: | ENSECAP00000020939.2 |
| Organism: | Equus caballus |
| Taxa ID: | 9796 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| P-body, Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSECAT00000025178.2 | ENSECAP00000020939.2 |
| Ensembl | ENSECAT00000041285.1 | ENSECAP00000032893.1 |
| Ensembl | ENSECAT00000049696.1 | ENSECAP00000041123.1 |
| UniProt | F6UJR9, F6UJR9_HORSE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEAAVGASDG GEQGGAGPRE DATPMDAYLR KLGLYRKLVA KDGSCLFRAV AEQVLHSQSR 60 61 HVEVRMACIH YLRENREKFE AFIEGSFEEY LKRLENPQEW VGQVEISALS LMYRKDFIIY 120 121 REPNVSPSQV TENNFPEKVL LCFSNGNHYD IVYPIKYKES SAMCQSLLYE LLYEKVFKTD 180 181 VSKILMGLDT SEVADENNSE ISDSEDDSCK SEAAAANDVN GLKALSSDQH LKNNGNSPNL 240 241 RLSRKVLKSL NPAVYRNVEY EIWLKSKQAQ QKRDYSIAAG LQYEVGDKCQ VRLDHNGKFS 300 301 NVDFQGVHSE NGPVLVEELG KKHSPKNLKP PPLESWNTVS GKKMKKPSTS GQNFHPDMDY 360 361 RGPKNPGSPS QKPSSEHKNL SRTPSQIIRK PDRERAEDSD HASRESNYFG LSPEERREKQ 420 421 AIEESRLLYE IQNRDEQAFP ALSSSSVSQS ASQSSNPCVQ RKSSHVGDRK GSRRRGDPEE 480 481 RKDKDSIHGH VHLDKKPEPS TLENISDDKC ARVSSPSKSK KLECPPPAEQ KPAEHVSLSN 540 541 PAPLLVSPEV HLTPAVPSLP ATVPAWPSEP TTFGPTGVPA QIPVLSVTQT LTTGPDSAVS 600 601 QAHLTPSPVP VSIQAVNQPM MPLPQTMSLY QDPLYPGFPY NEKGDRAIAP PYSLCHTGED 660 661 LPKDKNILRF FFNLGVKAYS CPMWAPHSYL YPLHQAYLAA CRMYPKVPVP VYPQNPWFQE 720 721 APSAQNESDC TCTDAHFPMQ TEASVNGQMP QAEIGPPTFS SPLVIPPSQV SESHGQLSYQ 780 781 ADLESENSGQ LLHAEYEESL SGKNMFPQPS FGPNPFLGPV PIAPPFFPHV WYGYPFQGFV 840 841 ENPVMRQNIV LPSDEKGELD LPLENLDLSK ECGSGAAVEE FQEARGEGTH CLPEASVSKH 900 901 EGRVEQSSQT PKADLALASV PPVAEGKAPL PTQILNRERE TVPVELEPKR TIPSLKEKPE 960 961 KVKDPKTAAD VVSGANSVDS RVQRPKEESS EDESEVSNIL RSGRSKQFYN QTYGGRKYKS 1020 1021 DWGYSGRGGY QHARGLFVLA QGILPYAEVK LGPSKLLSSS ILTESEFQKR RPETSSNRHE 1080 1081 VTPRLHSMRK DGWTWLPVSA ENCVGKRQTW ACARLAAGTN ICIKARSTPV KRALTVIVDI 1140 1141 FYRQTSPGLG SRFLQEKKPH NKTLRMLSHL FRFEVQESAS 1180 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAGGCGG CCGTCGGCGC CTCCGACGGC GGGGAGCAGG GCGGCGCGGG GCCCCGCGAG 60 61 GACGCGACGC CCATGGATGC CTATCTGCGG AAGCTGGGCT TGTATCGGAA ACTGGTCGCC 120 121 AAGGACGGGT CGTGTCTGTT CCGGGCCGTG GCGGAGCAGG TCTTGCACTC TCAGTCTCGC 180 181 CATGTTGAAG TCAGAATGGC CTGTATTCAC TATCTTCGAG AGAACAGAGA GAAATTTGAA 240 241 GCGTTTATAG AAGGGTCATT TGAAGAGTAT TTAAAACGTT TGGAAAATCC ACAGGAATGG 300 301 GTTGGACAAG TGGAAATAAG TGCCCTTTCT CTTATGTACA GGAAAGATTT TATAATTTAT 360 361 CGAGAACCAA ATGTTTCTCC TTCACAAGTA ACTGAAAATA ATTTTCCTGA AAAGGTATTA 420 421 CTGTGTTTTT CAAATGGAAA TCATTATGAT ATTGTCTATC CCATAAAGTA TAAAGAGAGC 480 481 TCTGCCATGT GTCAGTCTCT CCTTTATGAA TTGCTCTATG AGAAGGTATT TAAAACTGAT 540 541 GTTAGTAAAA TCTTGATGGG ACTAGACACC TCCGAAGTAG CTGATGAAAA CAACAGTGAA 600 601 ATATCAGATT CAGAGGATGA TAGTTGCAAG AGTGAAGCTG CCGCTGCTAA TGATGTGAAT 660 661 GGGTTGAAAG CTTTGTCGAG TGATCAGCAC CTGAAAAACA ATGGGAACTC TCCTAACCTG 720 721 CGTTTGTCTA GAAAGGTTCT TAAGTCACTC AATCCAGCAG TCTATAGAAA TGTGGAGTAT 780 781 GAAATTTGGC TGAAGTCTAA ACAAGCTCAA CAGAAACGTG ACTATTCCAT TGCTGCTGGC 840 841 TTACAGTATG AAGTTGGAGA TAAATGCCAA GTTAGGTTGG ATCACAATGG AAAATTTTCT 900 901 AATGTAGACT TTCAAGGTGT TCACTCTGAG AACGGACCAG TTTTGGTCGA AGAACTTGGA 960 961 AAGAAACACT CACCGAAGAA TCTCAAACCA CCTCCCTTAG AAAGCTGGAA CACAGTGTCA 1020 1021 GGGAAGAAGA TGAAAAAACC TTCTACTTCC GGACAAAACT TCCATCCTGA CATGGATTAC 1080 1081 AGAGGGCCAA AGAATCCAGG GTCTCCGTCT CAGAAACCCT CCAGTGAGCA CAAAAATCTT 1140 1141 AGCAGGACAC CCTCACAGAT CATAAGAAAA CCTGATCGTG AGAGAGCTGA GGATTCTGAT 1200 1201 CACGCGAGTC GAGAATCGAA CTATTTTGGC CTCTCCCCAG AAGAGCGCAG AGAGAAGCAA 1260 1261 GCTATAGAAG AATCTCGTTT ACTCTATGAG ATTCAGAACA GAGATGAACA GGCTTTCCCA 1320 1321 GCCCTTTCCA GCTCATCAGT TAGTCAGTCA GCTTCTCAGA GCAGCAACCC ATGCGTCCAG 1380 1381 AGAAAATCAT CACATGTGGG TGACAGAAAA GGAAGCAGGC GGAGAGGGGA TCCCGAAGAA 1440 1441 CGAAAAGATA AAGACTCTAT CCATGGGCAT GTTCACTTGG ATAAAAAACC CGAGCCAAGC 1500 1501 ACATTGGAGA ATATTAGTGA TGATAAATGT GCAAGAGTTT CATCACCGTC AAAGTCAAAG 1560 1561 AAATTGGAGT GCCCACCTCC TGCAGAACAA AAGCCAGCAG AACACGTGTC TTTGTCAAAT 1620 1621 CCAGCTCCCC TTCTAGTTTC TCCAGAGGTA CATCTAACTC CTGCGGTGCC TTCTTTACCA 1680 1681 GCCACTGTGC CAGCCTGGCC AAGTGAACCT ACAACTTTTG GACCAACAGG TGTTCCTGCT 1740 1741 CAAATTCCTG TTTTGTCTGT GACACAGACT CTGACCACTG GACCCGATTC TGCTGTGTCC 1800 1801 CAAGCTCATT TAACACCCTC TCCAGTTCCT GTGTCAATAC AGGCAGTTAA CCAGCCCATG 1860 1861 ATGCCTTTGC CTCAGACAAT GAGCCTTTAC CAAGACCCAC TCTATCCTGG GTTTCCTTAT 1920 1921 AATGAAAAGG GAGATCGAGC CATTGCACCA CCTTATTCAC TGTGTCACAC TGGGGAGGAC 1980 1981 CTGCCTAAAG ATAAGAACAT TCTTCGATTC TTCTTCAATC TTGGTGTAAA GGCATATAGT 2040 2041 TGTCCCATGT GGGCCCCGCA CTCTTACCTG TACCCTTTGC ACCAGGCCTA TCTGGCAGCC 2100 2101 TGCAGGATGT ACCCAAAGGT CCCTGTCCCT GTGTATCCTC AAAACCCTTG GTTCCAAGAA 2160 2161 GCTCCTTCTG CTCAGAATGA AAGTGATTGT ACCTGTACCG ATGCACACTT TCCTATGCAG 2220 2221 ACTGAGGCCA GTGTTAATGG TCAGATGCCA CAGGCAGAGA TTGGACCACC AACATTTTCT 2280 2281 TCACCTCTGG TTATCCCTCC ATCTCAGGTG TCTGAAAGTC ATGGACAGTT GTCTTACCAG 2340 2341 GCTGATCTTG AATCTGAAAA CTCTGGACAG CTTCTTCATG CTGAATATGA AGAGTCACTA 2400 2401 AGTGGCAAGA ATATGTTCCC ACAGCCGTCC TTTGGACCCA ATCCATTCTT AGGCCCAGTT 2460 2461 CCCATTGCAC CTCCTTTCTT TCCTCATGTT TGGTATGGGT ACCCTTTTCA GGGATTTGTA 2520 2521 GAAAATCCAG TAATGAGGCA GAATATTGTT TTGCCTTCTG ATGAGAAAGG AGAATTGGAT 2580 2581 CTGCCCCTGG AAAATTTGGA TCTGTCTAAA GAATGTGGTT CAGGTGCAGC AGTAGAGGAG 2640 2641 TTTCAGGAGG CCAGAGGTGA AGGCACACAT TGTCTCCCTG AAGCCAGTGT GAGTAAGCAT 2700 2701 GAAGGCCGGG TGGAGCAGTC GTCCCAGACA CCTAAGGCAG ATCTGGCATT GGCTTCCGTC 2760 2761 CCTCCTGTAG CAGAGGGAAA GGCTCCTCTT CCCACTCAGA TTCTGAACAG AGAGAGAGAA 2820 2821 ACTGTGCCTG TTGAACTTGA GCCTAAAAGG ACCATTCCAA GTCTGAAAGA AAAACCAGAA 2880 2881 AAAGTGAAAG ATCCTAAGAC TGCTGCTGAC GTGGTCAGTG GGGCCAACTC TGTGGATAGC 2940 2941 AGAGTGCAAA GACCAAAAGA AGAGAGTTCA GAAGACGAAA GTGAAGTGTC TAATATTCTG 3000 3001 AGAAGTGGTA GATCCAAGCA GTTCTATAAT CAGACTTATG GAGGCAGGAA GTACAAAAGC 3060 3061 GATTGGGGCT ATTCTGGTAG GGGAGGATAT CAACACGCGA GAGGTTTGTT TGTATTAGCC 3120 3121 CAGGGGATTT TGCCTTATGC TGAGGTCAAA CTAGGGCCAA GCAAGCTTTT GTCGTCCTCC 3180 3181 ATTTTAACTG AATCAGAGTT CCAGAAACGG AGACCAGAAA CCAGTAGCAA TAGACATGAA 3240 3241 GTGACACCAA GGCTGCACTC CATGAGAAAG GATGGATGGA CATGGTTGCC AGTCTCAGCT 3300 3301 GAGAACTGTG TAGACGACAG CACAAGCAAA TCTCTGCAAC TCTCCTCCTG A 3351 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Caf-0326 | Canis familiaris | 91.46 | 0.0 | 1863 |
| LLPS-Fec-1008 | Felis catus | 91.36 | 0.0 | 1849 |
| LLPS-Mam-4261 | Macaca mulatta | 89.53 | 0.0 | 1806 |
| LLPS-Man-4093 | Macaca nemestrina | 89.53 | 0.0 | 1807 |
| LLPS-Maf-0941 | Macaca fascicularis | 89.53 | 0.0 | 1806 |
| LLPS-Cea-3867 | Cercocebus atys | 89.44 | 0.0 | 1805 |
| LLPS-Paa-2651 | Papio anubis | 89.34 | 0.0 | 1802 |
| LLPS-Chs-0613 | Chlorocebus sabaeus | 89.34 | 0.0 | 1803 |
| LLPS-Aon-3848 | Aotus nancymaae | 89.25 | 0.0 | 1794 |
| LLPS-Caj-3841 | Callithrix jacchus | 89.06 | 0.0 | 1786 |
| LLPS-Hos-0897 | Homo sapiens | 88.96 | 0.0 | 1796 |
| LLPS-Pat-3478 | Pan troglodytes | 88.87 | 0.0 | 1792 |
| LLPS-Mal-2706 | Mandrillus leucophaeus | 88.83 | 0.0 | 1704 |
| LLPS-Ict-2665 | Ictidomys tridecemlineatus | 88.82 | 0.0 | 1720 |
| LLPS-Poa-2289 | Pongo abelii | 88.78 | 0.0 | 1787 |
| LLPS-Sus-1860 | Sus scrofa | 88.74 | 0.0 | 1800 |
| LLPS-Myl-4432 | Myotis lucifugus | 87.93 | 0.0 | 1771 |
| LLPS-Otg-0588 | Otolemur garnettii | 87.82 | 0.0 | 1786 |
| LLPS-Urm-0031 | Ursus maritimus | 87.8 | 0.0 | 1665 |
| LLPS-Cas-0835 | Carlito syrichta | 87.72 | 0.0 | 1692 |
| LLPS-Pap-0615 | Pan paniscus | 87.59 | 0.0 | 1690 |
| LLPS-Orc-3195 | Oryctolagus cuniculus | 87.32 | 0.0 | 1065 |
| LLPS-Mup-4395 | Mustela putorius furo | 87.0 | 0.0 | 1740 |
| LLPS-Bot-1378 | Bos taurus | 86.84 | 0.0 | 1729 |
| LLPS-Cap-1258 | Cavia porcellus | 86.38 | 0.0 | 1701 |
| LLPS-Rhb-3945 | Rhinopithecus bieti | 86.34 | 0.0 | 1720 |
| LLPS-Fud-1900 | Fukomys damarensis | 85.8 | 0.0 | 1666 |
| LLPS-Nol-0515 | Nomascus leucogenys | 85.44 | 0.0 | 1688 |
| LLPS-Ova-4118 | Ovis aries | 85.04 | 0.0 | 1653 |
| LLPS-Ran-3836 | Rattus norvegicus | 83.61 | 0.0 | 1658 |
| LLPS-Ere-0518 | Erinaceus europaeus | 83.05 | 0.0 | 1553 |
| LLPS-Loa-3676 | Loxodonta africana | 83.0 | 0.0 | 1491 |
| LLPS-Gog-4309 | Gorilla gorilla | 82.41 | 0.0 | 1614 |
| LLPS-Mod-4176 | Monodelphis domestica | 69.55 | 0.0 | 1371 |
| LLPS-Sah-0131 | Sarcophilus harrisii | 69.09 | 0.0 | 1269 |
| LLPS-Leo-2919 | Lepisosteus oculatus | 65.24 | 2e-67 | 237 |
| LLPS-Ora-2222 | Ornithorhynchus anatinus | 62.61 | 0.0 | 1075 |
| LLPS-Orl-3713 | Oryzias latipes | 62.22 | 2e-23 | 112 |
| LLPS-Dar-1896 | Danio rerio | 60.0 | 3e-20 | 101 |
| LLPS-Scm-1334 | Scophthalmus maximus | 59.74 | 3e-19 | 98.6 |
| LLPS-Pes-3024 | Pelodiscus sinensis | 58.48 | 0.0 | 1112 |
| LLPS-Asm-2050 | Astyanax mexicanus | 58.44 | 1e-18 | 96.3 |
| LLPS-Xim-3163 | Xiphophorus maculatus | 58.06 | 8e-24 | 113 |
| LLPS-Meg-0611 | Meleagris gallopavo | 56.8 | 0.0 | 1038 |
| LLPS-Anp-1661 | Anas platyrhynchos | 56.77 | 0.0 | 1023 |
| LLPS-Gaga-1289 | Gallus gallus | 56.49 | 0.0 | 1053 |
| LLPS-Tag-0710 | Taeniopygia guttata | 56.02 | 0.0 | 1052 |
| LLPS-Fia-2149 | Ficedula albicollis | 55.55 | 0.0 | 1033 |
| LLPS-Anc-3453 | Anolis carolinensis | 49.44 | 0.0 | 875 |
| LLPS-Pof-4192 | Poecilia formosa | 45.93 | 4e-89 | 299 |
| LLPS-Icp-2824 | Ictalurus punctatus | 44.96 | 2e-79 | 285 |
| LLPS-Scf-2841 | Scleropages formosus | 44.93 | 1e-33 | 145 |
| LLPS-Xet-2051 | Xenopus tropicalis | 44.25 | 0.0 | 768 |
| LLPS-Aim-2566 | Ailuropoda melanoleuca | 41.57 | 1e-73 | 270 |
| LLPS-Lac-0809 | Latimeria chalumnae | 39.77 | 9e-66 | 245 |
| LLPS-Drm-1120 | Drosophila melanogaster | 39.39 | 2e-32 | 140 |
| LLPS-Sem-1533 | Selaginella moellendorffii | 37.25 | 4e-08 | 59.3 |
| LLPS-Orn-2830 | Oreochromis niloticus | 35.92 | 4e-33 | 142 |
| LLPS-Tra-2873 | Triticum aestivum | 35.78 | 7e-08 | 60.1 |
| LLPS-Tru-0481 | Triticum urartu | 34.86 | 2e-07 | 58.5 |
| LLPS-Hov-0028 | Hordeum vulgare | 34.86 | 2e-07 | 58.9 |
| LLPS-Thc-2334 | Theobroma cacao | 34.68 | 1e-12 | 76.6 |
| LLPS-Sob-0069 | Sorghum bicolor | 33.94 | 3e-06 | 54.7 |
| LLPS-Beb-0349 | Beauveria bassiana | 31.78 | 4e-06 | 54.3 |
| LLPS-Tar-1885 | Takifugu rubripes | 31.34 | 5e-11 | 70.9 |
| LLPS-Ten-3225 | Tetraodon nigroviridis | 31.01 | 2e-11 | 72.0 |
| LLPS-Tum-0552 | Tuber melanosporum | 30.0 | 4e-10 | 66.6 |
| LLPS-Fuo-1188 | Fusarium oxysporum | 29.63 | 2e-07 | 58.2 |
| LLPS-Fus-1379 | Fusarium solani | 29.36 | 7e-07 | 56.6 |
| LLPS-Brd-1467 | Brachypodium distachyon | 28.75 | 5e-08 | 60.5 |
| LLPS-Put-1348 | Puccinia triticina | 28.43 | 5e-08 | 61.6 |
| LLPS-Sei-0702 | Setaria italica | 28.12 | 5e-06 | 54.3 |
| LLPS-Cae-1536 | Caenorhabditis elegans | 27.74 | 1e-06 | 56.2 |
| LLPS-Mel-1143 | Melampsora laricipopulina | 27.73 | 9e-09 | 62.0 |
| LLPS-Fuv-1355 | Fusarium verticillioides | 26.76 | 2e-07 | 58.2 |