LLPS-Eqc-2158
CYFIP2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Cytoplasmic FMR1-interacting protein |
| Gene Name: | CYFIP2 |
| Ensembl Gene: | ENSECAG00000011994.2 |
| Ensembl Protein: | ENSECAP00000010838.1 |
| Organism: | Equus caballus |
| Taxa ID: | 9796 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSECAT00000013636.2 | ENSECAP00000010838.1 |
| Ensembl | ENSECAT00000062752.1 | ENSECAP00000033790.1 |
| UniProt | F6RGZ9, F6RGZ9_HORSE | |
| RefSeq | XM_001500928.5, XM_014730547.1, XM_014730548.1 | XP_001500978.2, XP_014586033.1, XP_014586034.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTTHVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSIMYQA NFDTNFEDRN AFVTGIARYI 60 61 EQATVHSSMN EMLEEGHEYA VMLYTWRSCS RAIPQVKCNE QPNRVEIYEK TVEVLEPEVT 120 121 KLMKFMYFQR KAIERFCSEV KRLCHAERRK DFVSEAYLLT LGKFINMFAV LDELKNMKCS 180 181 VKNDHSAYKR AAQFLRKMAD PQSIQESQNL SMFLANHNRI TQCLHQQLEV IPGYEELLAD 240 241 IVNICVDYYE NKMYLTPSEK HMLLKVMGFG LYLMDGNVSN IYKLDAKKRI NLSKIDKFFK 300 301 QLQVVPLFGD MQIELARYIK TSAHYEENKS KWTCTQSSIS PQYNICEQMV QIRDDHIRFI 360 361 SELARYSNSE VVTGSGLDSQ KSDEEYRELF DLALRGLQLL SKWSAHVMEV YSWKLVHPTD 420 421 KFCNKDCPGT AEEYERATRY NYTSEEKFAF VEVIAMIKGL QVLMGRMESV FNQAIRNTIY 480 481 AALQDFAQVT LREPLRQAVR KKKNVLISVL QAIRKTICDW EGGREPPNDP CLRGEKDPKG 540 541 GFDIKVPRRA VGPSSTQACQ WSPRALFHPT GGTQGRRGCR SLLYMVRTML ESLIADKSGS 600 601 KKTLRSSLDG PIVLAIEDFH KQSFFFTHLL NISEALQQCC DLSQLWFREF FLELTMGRRI 660 661 QFPIEMSMPW ILTDHILETK EPSMMEYVLY PLDLYNDSAY YALTKFKKQF LYDEIEAEVN 720 721 LCFDQFVYKL ADQIFAYYKA MAGSVLLDKR FRAECKNYGV IIPYPPSNRY ETLLKQRHVQ 780 781 LLGRSIDLNR LITQRISAAM YKSLDQAISR FESEDLTSIV ELEWLLEINR LTHRLLCKHM 840 841 TLDSFDAMFR EANHNVSAPY GRITLHVFWE LNFDFLPNYC YNGSTNRFVR TAIPFTQEPQ 900 901 RDKPANVQPY YLYGSKPLNI AYSHIYSSYR NFVGPPHFKT ICRLLGYQGI AVVMEELLKI 960 961 VKSLLQGTIL QYVKTLIEVM PKICRLPRHE YGSPGILEFF HHQLKDIIEY AELKTDVFQS 1020 1021 LREVGNAILF CLLIEQALSQ EEVCDLLHAA PFQNILPRVY IKEGERLEVR MKRLEAKYAP 1080 1081 LHLVPLIERL GTPQQIAIAR EGDLLTKERL CCGLSMFEVI LTRIRSYLQD PIWRGPPPTN 1140 1141 GVMHVDECVE FHRLWSAMQF VYCIPVGTNE FTAEQCFGDG LNWAGCSIIV LLGQQRRFDL 1200 1201 FDFCYHLLKV QRQDGKDEII KNVPLKKMAD RIRKYQILNN EVFAILNKYM KSVETDSSTV 1260 1261 EHVRCFQPPI HQSLATTC 1278 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACCACCC ACGTCACCCT GGAAGATGCC CTGTCCAACG TGGACCTGCT GGAAGAGCTG 60 61 CCCCTCCCTG ACCAGCAGCC ATGCATCGAG CCCCCACCTT CCTCCATCAT GTACCAGGCT 120 121 AACTTTGACA CAAACTTCGA GGACAGGAAT GCATTTGTCA CAGGCATTGC AAGGTACATT 180 181 GAGCAGGCTA CGGTCCACTC CAGCATGAAT GAAATGCTGG AGGAAGGGCA CGAGTATGCC 240 241 GTCATGCTGT ACACCTGGCG TAGCTGTTCC AGGGCCATCC CCCAGGTGAA ATGCAACGAG 300 301 CAGCCCAACC GAGTGGAGAT CTATGAGAAG ACAGTGGAGG TGCTGGAGCC AGAGGTGACC 360 361 AAGCTCATGA AGTTCATGTA CTTTCAGCGC AAAGCCATCG AGCGGTTCTG CAGCGAGGTG 420 421 AAGCGGCTGT GCCACGCCGA GCGGAGGAAG GACTTTGTCT CCGAGGCCTA CCTCCTGACC 480 481 CTGGGCAAGT TCATCAACAT GTTCGCTGTC TTGGACGAGC TGAAGAATAT GAAGTGCAGC 540 541 GTCAAGAACG ACCACTCTGC CTACAAGAGG GCGGCACAGT TCCTGAGGAA GATGGCGGAC 600 601 CCCCAGTCTA TCCAGGAGTC ACAGAACCTT TCCATGTTCC TGGCCAACCA CAACAGGATC 660 661 ACCCAGTGTC TCCATCAGCA ACTGGAAGTG ATCCCGGGCT ATGAGGAGCT GCTGGCCGAC 720 721 ATCGTCAACA TCTGCGTGGA TTACTACGAG AACAAGATGT ACCTGACCCC CAGTGAGAAG 780 781 CACATGCTCC TCAAGGTAAT GGGTTTTGGT CTCTACCTGA TGGATGGAAA TGTCAGTAAC 840 841 ATTTACAAAC TGGATGCCAA GAAGAGAATC AACCTCAGCA AAATTGATAA GTTCTTTAAG 900 901 CAGCTGCAGG TGGTGCCCCT TTTCGGCGAC ATGCAGATAG AGCTGGCCAG ATACATTAAG 960 961 ACCAGTGCTC ACTATGAAGA GAACAAGTCC AAGTGGACGT GCACCCAGAG CAGCATCAGC 1020 1021 CCCCAGTACA ACATCTGCGA GCAGATGGTT CAGATCCGGG ATGACCACAT CCGCTTCATC 1080 1081 TCCGAACTTG CTCGCTACAG CAACAGTGAG GTGGTGACAG GCTCCGGGCT GGACAGCCAG 1140 1141 AAGTCGGACG AGGAGTACCG CGAGCTCTTC GACCTGGCCC TGCGGGGCCT GCAGCTTTTA 1200 1201 TCCAAGTGGA GCGCCCACGT CATGGAGGTG TACTCCTGGA AGCTGGTTCA CCCCACCGAC 1260 1261 AAGTTCTGCA ACAAGGACTG CCCCGGCACG GCAGAGGAGT ACGAGCGAGC CACGCGCTAC 1320 1321 AACTACACCA GCGAGGAGAA GTTTGCCTTT GTCGAGGTGA TCGCCATGAT CAAAGGCCTG 1380 1381 CAGGTGCTCA TGGGCAGGAT GGAGAGTGTC TTCAACCAGG CCATCAGGAA CACCATCTAC 1440 1441 GCGGCTCTGC AGGACTTTGC CCAGGTGACC CTGCGCGAGC CCCTGAGGCA GGCAGTGCGA 1500 1501 AAGAAAAAGA ACGTCCTCAT CAGTGTCCTG CAGGCAATTC GGAAAACCAT CTGTGACTGG 1560 1561 GAGGGGGGCC GAGAGCCCCC CAATGACCCG TGCTTGAGAG GGGAGAAGGA TCCCAAAGGT 1620 1621 GGCTTTGACA TCAAGGTGCC CCGGCGTGCT GTGGGGCCCT CCAGCACACA GCTGTACATG 1680 1681 GTGCGGACCA TGCTTGAGTC ACTCATCGCA GACAAAAGTG GCTCCAAGAA GACTCTGAGG 1740 1741 AGCAGCCTGG ACGGACCCAT TGTCCTCGCC ATAGAGGACT TCCACAAGCA GTCATTCTTC 1800 1801 TTCACGCACC TGCTCAACAT CAGTGAAGCC CTGCAGCAGT GTTGCGACCT CTCCCAGCTC 1860 1861 TGGTTCCGAG AATTCTTCCT GGAGTTAACC ATGGGTCGGC GAATCCAGTT TCCCATTGAG 1920 1921 ATGTCCATGC CCTGGATTCT AACAGACCAT ATCCTGGAAA CCAAAGAACC TTCCATGATG 1980 1981 GAGTACGTCC TGTACCCTTT GGATCTGTAC AACGACAGCG CCTACTATGC TCTGACCAAG 2040 2041 TTCAAAAAGC AGTTCCTGTA CGATGAGATC GAAGCCGAGG TGAACCTGTG CTTTGATCAG 2100 2101 TTTGTCTACA AGCTGGCGGA CCAGATCTTC GCTTACTACA AAGCCATGGC CGGCAGTGTC 2160 2161 CTGTTGGATA AACGTTTTAG GGCCGAATGT AAGAATTATG GAGTCATCAT TCCGTACCCA 2220 2221 CCGTCCAACC GCTATGAAAC GCTACTGAAG CAGAGACACG TGCAGCTGTT AGGTAGATCT 2280 2281 ATTGACTTGA ACAGACTCAT TACCCAGCGC ATCTCTGCCG CCATGTATAA ATCCTTGGAC 2340 2341 CAGGCCATCA GCCGCTTTGA GAGTGAGGAC CTGACCTCCA TCGTGGAGCT GGAGTGGTTG 2400 2401 CTGGAGATCA ACCGGCTCAC ACACCGGCTG CTGTGTAAGC ACATGACCCT GGACAGCTTC 2460 2461 GATGCCATGT TCCGGGAGGC CAATCACAAC GTGTCTGCCC CCTACGGACG CATCACCCTG 2520 2521 CACGTCTTCT GGGAGCTGAA CTTCGACTTC CTCCCTAACT ACTGCTACAA TGGGTCCACC 2580 2581 AACCGTTTTG TCCGAACTGC CATTCCTTTT ACCCAAGAGC CACAAAGAGA TAAACCTGCC 2640 2641 AACGTCCAGC CTTATTACCT CTATGGGTCC AAGCCTCTCA ACATTGCCTA CAGCCACATC 2700 2701 TACAGCTCCT ACAGAAACTT CGTGGGGCCT CCTCATTTCA AGACCATCTG CAGGCTCCTG 2760 2761 GGTTACCAGG GCATCGCTGT GGTCATGGAA GAACTGCTGA AGATCGTCAA GAGCTTGCTC 2820 2821 CAGGGCACCA TTCTCCAGTA CGTGAAAACG CTGATCGAGG TGATGCCCAA GATATGCCGC 2880 2881 TTGCCCCGGC ACGAGTACGG CTCCCCAGGG ATCCTGGAGT TCTTCCACCA CCAGCTGAAG 2940 2941 GACATCATTG AGTACGCAGA GCTCAAAACA GACGTGTTCC AGAGCCTGAG GGAGGTGGGC 3000 3001 AATGCCATCC TGTTCTGCCT GCTTATAGAG CAAGCTCTGT CTCAGGAGGA AGTCTGTGAT 3060 3061 TTGCTCCATG CTGCACCCTT CCAGAACATC CTGCCTCGAG TCTACATCAA AGAGGGGGAG 3120 3121 CGTCTGGAGG TCCGGATGAA ACGCCTGGAA GCCAAGTACG CCCCGCTTCA CCTGGTCCCT 3180 3181 CTGATCGAGC GGCTGGGGAC CCCTCAGCAA ATCGCCATCG CTCGAGAGGG TGACCTGCTG 3240 3241 ACCAAGGAGC GGCTATGCTG CGGCCTGTCC ATGTTCGAGG TCATCCTGAC CCGCATCCGG 3300 3301 AGCTACCTGC AGGACCCCAT CTGGCGGGGC CCACCGCCCA CCAACGGCGT CATGCACGTT 3360 3361 GACGAGTGCG TGGAGTTCCA CCGGCTCTGG AGTGCCATGC AGTTTGTCTA CTGCATCCCC 3420 3421 GTGGGGACCA ACGAGTTCAC AGCTGAGCAG TGTTTCGGTG ATGGCTTGAA CTGGGCTGGC 3480 3481 TGCTCCATCA TCGTCCTGCT GGGCCAGCAG CGTCGCTTCG ACCTGTTTGA CTTCTGTTAC 3540 3541 CACCTGCTAA AAGTACAGAG GCAGGACGGG AAGGATGAAA TCATTAAGAA TGTGCCCCTG 3600 3601 AAGAAGATGG CAGACAGAAT TAGGAAGTAC CAGATTTTGA ACAATGAGGT TTTTGCCATC 3660 3661 CTGAATAAGT ACATGAAGTC CGTGGAGACA GACAGTTCCA CCGTGGAGCA TGTGCGCTGC 3720 3721 TTCCAGCCCC CCATCCACCA GTCCTTGGCC ACCACCTGCT AG 3762 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mam-4030 | Macaca mulatta | 100.0 | 0.0 | 2640 |
| LLPS-Nol-1987 | Nomascus leucogenys | 100.0 | 0.0 | 2640 |
| LLPS-Pat-1067 | Pan troglodytes | 100.0 | 0.0 | 2640 |
| LLPS-Pap-3410 | Pan paniscus | 100.0 | 0.0 | 2640 |
| LLPS-Hos-1701 | Homo sapiens | 100.0 | 0.0 | 2640 |
| LLPS-Rhb-3169 | Rhinopithecus bieti | 100.0 | 0.0 | 2640 |
| LLPS-Paa-1075 | Papio anubis | 100.0 | 0.0 | 2640 |
| LLPS-Mal-0882 | Mandrillus leucophaeus | 100.0 | 0.0 | 2640 |
| LLPS-Maf-1302 | Macaca fascicularis | 100.0 | 0.0 | 2640 |
| LLPS-Cea-2249 | Cercocebus atys | 100.0 | 0.0 | 2640 |
| LLPS-Gog-3053 | Gorilla gorilla | 100.0 | 0.0 | 2640 |
| LLPS-Caj-0154 | Callithrix jacchus | 100.0 | 0.0 | 2640 |
| LLPS-Fud-2962 | Fukomys damarensis | 100.0 | 0.0 | 2640 |
| LLPS-Cas-1709 | Carlito syrichta | 99.92 | 0.0 | 2638 |
| LLPS-Ict-0581 | Ictidomys tridecemlineatus | 99.92 | 0.0 | 2640 |
| LLPS-Fec-1401 | Felis catus | 99.92 | 0.0 | 2640 |
| LLPS-Man-4827 | Macaca nemestrina | 99.92 | 0.0 | 2639 |
| LLPS-Aim-2092 | Ailuropoda melanoleuca | 99.84 | 0.0 | 2638 |
| LLPS-Mea-0999 | Mesocricetus auratus | 98.36 | 0.0 | 2583 |
| LLPS-Meg-3033 | Meleagris gallopavo | 98.28 | 0.0 | 2582 |
| LLPS-Orc-3265 | Oryctolagus cuniculus | 98.04 | 0.0 | 2570 |
| LLPS-Chs-3585 | Chlorocebus sabaeus | 98.04 | 0.0 | 2570 |
| LLPS-Sus-3211 | Sus scrofa | 98.04 | 0.0 | 2570 |
| LLPS-Caf-0560 | Canis familiaris | 97.97 | 0.0 | 2568 |
| LLPS-Mup-4111 | Mustela putorius furo | 97.97 | 0.0 | 2569 |
| LLPS-Mum-3830 | Mus musculus | 97.97 | 0.0 | 2568 |
| LLPS-Gaga-2152 | Gallus gallus | 97.89 | 0.0 | 2570 |
| LLPS-Tag-0771 | Taeniopygia guttata | 97.89 | 0.0 | 2568 |
| LLPS-Bot-1576 | Bos taurus | 97.89 | 0.0 | 2568 |
| LLPS-Ova-3975 | Ovis aries | 97.89 | 0.0 | 2563 |
| LLPS-Ora-0284 | Ornithorhynchus anatinus | 97.89 | 0.0 | 2576 |
| LLPS-Anc-0301 | Anolis carolinensis | 97.81 | 0.0 | 2569 |
| LLPS-Fia-3400 | Ficedula albicollis | 97.81 | 0.0 | 2562 |
| LLPS-Poa-1716 | Pongo abelii | 97.73 | 0.0 | 2561 |
| LLPS-Sah-2465 | Sarcophilus harrisii | 97.73 | 0.0 | 2568 |
| LLPS-Urm-1963 | Ursus maritimus | 97.5 | 0.0 | 2191 |
| LLPS-Cap-3297 | Cavia porcellus | 97.27 | 0.0 | 2545 |
| LLPS-Myl-0987 | Myotis lucifugus | 97.03 | 0.0 | 2538 |
| LLPS-Pes-3224 | Pelodiscus sinensis | 96.64 | 0.0 | 2532 |
| LLPS-Leo-3634 | Lepisosteus oculatus | 96.57 | 0.0 | 2538 |
| LLPS-Xet-2132 | Xenopus tropicalis | 96.48 | 0.0 | 2538 |
| LLPS-Orl-2277 | Oryzias latipes | 96.4 | 0.0 | 2533 |
| LLPS-Pof-2280 | Poecilia formosa | 96.32 | 0.0 | 2530 |
| LLPS-Dar-2607 | Danio rerio | 96.24 | 0.0 | 2527 |
| LLPS-Orn-2404 | Oreochromis niloticus | 96.17 | 0.0 | 2524 |
| LLPS-Scm-3800 | Scophthalmus maximus | 96.09 | 0.0 | 2525 |
| LLPS-Ten-1582 | Tetraodon nigroviridis | 95.94 | 0.0 | 2528 |
| LLPS-Icp-0890 | Ictalurus punctatus | 95.63 | 0.0 | 2506 |
| LLPS-Gaa-3633 | Gasterosteus aculeatus | 95.18 | 0.0 | 2506 |
| LLPS-Dio-1625 | Dipodomys ordii | 94.32 | 0.0 | 2356 |
| LLPS-Otg-0732 | Otolemur garnettii | 94.29 | 0.0 | 2452 |
| LLPS-Loa-0937 | Loxodonta africana | 90.53 | 0.0 | 2349 |
| LLPS-Lac-0449 | Latimeria chalumnae | 86.31 | 0.0 | 2211 |
| LLPS-Cis-1345 | Ciona savignyi | 72.21 | 0.0 | 625 |
| LLPS-Amt-0884 | Amborella trichopoda | 33.66 | 4e-139 | 454 |
| LLPS-Mua-2579 | Musa acuminata | 33.06 | 2e-113 | 379 |
| LLPS-Orp-2193 | Oryza punctata | 31.73 | 2e-125 | 423 |
| LLPS-Sei-1441 | Setaria italica | 31.17 | 1e-109 | 370 |
| LLPS-Orm-1496 | Oryza meridionalis | 31.12 | 6e-123 | 417 |
| LLPS-Via-1811 | Vigna angularis | 30.92 | 7e-157 | 512 |
| LLPS-Orr-1415 | Oryza rufipogon | 30.86 | 2e-119 | 408 |
| LLPS-Zem-2325 | Zea mays | 30.56 | 1e-134 | 446 |
| LLPS-Glm-1866 | Glycine max | 30.35 | 8e-154 | 503 |
| LLPS-Brr-2297 | Brassica rapa | 30.26 | 3e-157 | 513 |
| LLPS-Ors-1687 | Oryza sativa | 30.24 | 9e-164 | 530 |
| LLPS-Ori-0433 | Oryza indica | 30.21 | 3e-163 | 529 |
| LLPS-Bro-2171 | Brassica oleracea | 30.2 | 1e-158 | 516 |
| LLPS-Nia-2321 | Nicotiana attenuata | 30.17 | 1e-152 | 500 |
| LLPS-Brn-0579 | Brassica napus | 30.15 | 2e-158 | 516 |
| LLPS-Met-1868 | Medicago truncatula | 30.1 | 1e-151 | 498 |
| LLPS-Pot-0095 | Populus trichocarpa | 30.09 | 6e-156 | 509 |
| LLPS-Mae-2230 | Manihot esculenta | 30.08 | 5e-148 | 486 |
| LLPS-Orni-0091 | Oryza nivara | 29.98 | 2e-114 | 395 |
| LLPS-Brd-0157 | Brachypodium distachyon | 29.93 | 9e-160 | 520 |
| LLPS-Thc-1028 | Theobroma cacao | 29.91 | 4e-153 | 503 |
| LLPS-Art-2139 | Arabidopsis thaliana | 29.85 | 3e-153 | 502 |
| LLPS-Tra-0919 | Triticum aestivum | 29.84 | 2e-155 | 508 |
| LLPS-Sob-0715 | Sorghum bicolor | 29.8 | 7e-158 | 514 |
| LLPS-Arl-2691 | Arabidopsis lyrata | 29.62 | 6e-153 | 501 |
| LLPS-Coc-0051 | Corchorus capsularis | 29.61 | 1e-148 | 488 |
| LLPS-Php-1784 | Physcomitrella patens | 29.57 | 2e-157 | 514 |
| LLPS-Orbr-1003 | Oryza brachyantha | 29.48 | 2e-158 | 516 |
| LLPS-Org-0744 | Oryza glaberrima | 29.28 | 8e-154 | 503 |
| LLPS-Hov-1984 | Hordeum vulgare | 28.98 | 2e-146 | 486 |
| LLPS-Lep-1013 | Leersia perrieri | 28.61 | 5e-144 | 476 |
| LLPS-Vir-0299 | Vigna radiata | 28.23 | 1e-131 | 443 |
| LLPS-Orb-1784 | Oryza barthii | 27.99 | 5e-128 | 436 |
| LLPS-Orgl-2300 | Oryza glumaepatula | 27.93 | 8e-126 | 429 |