• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-2142
CTSC

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Cathepsin C
Gene Name: CTSC
Ensembl Gene: ENSECAG00000020881.2
Ensembl Protein: ENSECAP00000040651.1
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSVSLSLSDL  WRYHPPPAPQ  ISLFLSVTSP  GAKSGSRAGP  LWLFNPILRR  PLAMEPVPGI  60
61    SPGSRSGQSQ  VRGNEHSQSP  PPPAPQPRSS  PAHRFPSLEA  PGRPAPRDPA  PAARRVSGPA  120
121   GYFRAREVQV  VLLPACRPPV  LLPLPPPLRA  PATMGPWSGS  FLAAFLVLLS  TVGPARCDTP  180
181   ANCTYPDLLG  TWVFQVGRSG  SQRDVNCSVV  GPPEKKVVVH  LEKLDTAYDD  LGNSGHFTIV  240
241   YNQGFEIVLN  DYKWFAFFKY  EEEGIQVTSY  CNETMPGWVH  DVLGRNWACF  TGSKVGTTSE  300
301   TMSKKTANLK  SLSEKHSNRL  YKYNHDFVKA  INAAQKSWTA  TTYMEYETLT  LKEMVRRGGG  360
361   HSRRIPRPKP  APLTAEIQEK  ILHLPTSWDW  RNVHGINYVA  PVRNQASCGS  CYSFASMGML  420
421   EARIRILTNN  SQTPILSPQE  VVSCSQYAQG  CEGGFPYLIA  GKYAQDFGVV  EEGCFPYTGT  480
481   DSPCKLKKDC  FRYYSSDYYY  VGGFYGGCNE  ALMKLELVHH  GPMAVAFEVY  NDFLHYHDGI  540
541   YHHTGLRDPF  NPFELTNHAV  LLVGYGTDSA  SGQDYWIVKN  SWGTSWGEDG  YFRIRRGTDE  600
601   CAIESIAMAA  TPIPKL  616
Nucleotide CDS Sequence (FASTA)
1     ATGTCTGTCT  CTCTCTCTCT  CTCTGACCTT  TGGCGGTACC  ACCCCCCCCC  CGCCCCCCAA  60
61    ATTTCTCTCT  TTCTCTCCGT  TACTTCTCCA  GGAGCGAAGT  CTGGGTCGCG  TGCGGGCCCA  120
121   CTGTGGCTCT  TTAATCCTAT  TTTGAGACGT  CCCTTGGCAA  TGGAACCGGT  CCCTGGGATC  180
181   TCCCCAGGTT  CAAGGTCGGG  CCAAAGCCAG  GTGAGGGGCA  ACGAGCACTC  CCAGTCTCCA  240
241   CCTCCCCCCG  CCCCCCAGCC  CCGCAGCTCT  CCAGCTCACC  GGTTCCCCAG  CCTGGAGGCG  300
301   CCCGGACGCC  CCGCCCCCCG  AGACCCCGCC  CCCGCCGCGC  GGCGGGTTTC  CGGCCCAGCT  360
361   GGCTATTTCA  GGGCGCGCGA  GGTGCAGGTC  GTCTTGCTCC  CAGCCTGCCG  CCCTCCGGTT  420
421   CTGCTGCCTC  TCCCACCTCC  CCTCCGGGCC  CCGGCCACCA  TGGGTCCCTG  GTCCGGCTCG  480
481   TTCCTCGCCG  CCTTCCTGGT  GCTCCTCTCC  ACCGTGGGCC  CCGCGCGCTG  CGACACACCT  540
541   GCCAACTGCA  CCTACCCTGA  CCTGCTGGGC  ACCTGGGTCT  TCCAGGTGGG  CCGCAGCGGT  600
601   TCCCAACGCG  ACGTCAACTG  CTCCGTTGTG  GGACCACCAG  AAAAAAAAGT  AGTGGTGCAC  660
661   CTTGAGAAGT  TGGATACAGC  GTATGATGAC  TTAGGCAATT  CTGGCCATTT  CACCATCGTT  720
721   TACAATCAAG  GCTTTGAGAT  TGTGTTGAAT  GACTACAAGT  GGTTTGCCTT  TTTTAAGTAT  780
781   GAAGAAGAGG  GCATCCAGGT  AACCAGTTAC  TGCAATGAGA  CGATGCCTGG  CTGGGTGCAT  840
841   GATGTGCTGG  GCCGAAACTG  GGCTTGTTTC  ACTGGAAGCA  AGGTGGGGAC  CACCTCTGAG  900
901   ACCATGAGCA  AGAAGACAGC  AAACCTTAAG  AGTCTCTCGG  AAAAGCATTC  TAATAGGCTC  960
961   TACAAATATA  ACCACGATTT  TGTGAAAGCC  ATCAATGCTG  CTCAGAAGTC  TTGGACTGCA  1020
1021  ACCACATACA  TGGAGTATGA  GACCCTTACC  CTGAAAGAGA  TGGTTAGGAG  AGGTGGTGGC  1080
1081  CACAGCCGGA  GAATCCCAAG  GCCCAAACCT  GCACCACTGA  CTGCTGAAAT  ACAGGAAAAG  1140
1141  ATTTTACATT  TGCCGACATC  TTGGGACTGG  AGAAATGTTC  ACGGTATCAA  TTATGTTGCC  1200
1201  CCTGTTCGAA  ACCAAGCATC  TTGTGGAAGC  TGCTACTCAT  TTGCTTCTAT  GGGTATGCTG  1260
1261  GAAGCACGAA  TCCGTATCCT  CACCAACAAC  TCTCAGACCC  CAATCTTGAG  TCCTCAGGAG  1320
1321  GTTGTGTCTT  GCAGCCAGTA  TGCTCAAGGT  TGTGAAGGTG  GCTTCCCATA  CCTCATCGCA  1380
1381  GGAAAGTACG  CCCAAGATTT  TGGGGTGGTG  GAAGAGGGGT  GCTTCCCCTA  CACAGGCACC  1440
1441  GATTCGCCAT  GCAAACTGAA  AAAGGACTGC  TTTCGTTACT  ACTCCTCCGA  TTACTACTAT  1500
1501  GTGGGAGGTT  TCTATGGGGG  CTGCAATGAA  GCCCTGATGA  AGCTTGAGCT  GGTCCATCAT  1560
1561  GGGCCCATGG  CAGTTGCTTT  TGAAGTCTAT  AATGACTTCC  TCCACTACCA  TGACGGGATC  1620
1621  TACCACCACA  CTGGTCTGAG  AGACCCTTTC  AACCCGTTTG  AGCTGACTAA  TCATGCTGTT  1680
1681  CTGCTGGTGG  GCTATGGTAC  TGACTCAGCC  TCCGGGCAGG  ATTACTGGAT  TGTTAAAAAC  1740
1741  AGCTGGGGCA  CCAGCTGGGG  CGAGGACGGT  TACTTCCGGA  TCCGCAGAGG  AACTGACGAG  1800
1801  TGTGCAATCG  AAAGCATAGC  CATGGCAGCC  ACGCCAATTC  CTAAATTGTA  G  1851

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Paa-4150Papio anubis88.910.0 849
LLPS-Mal-4374Mandrillus leucophaeus88.910.0 849
LLPS-Gog-1181Gorilla gorilla88.910.0 847
LLPS-Poa-1648Pongo abelii88.910.0 845
LLPS-Pat-0398Pan troglodytes88.910.0 847
LLPS-Pap-3130Pan paniscus88.910.0 847
LLPS-Cea-1347Cercocebus atys88.690.0 847
LLPS-Maf-4647Macaca fascicularis88.690.0 845
LLPS-Chs-3591Chlorocebus sabaeus88.690.0 847
LLPS-Hos-0409Homo sapiens88.510.0 847
LLPS-Man-1338Macaca nemestrina88.460.0 844
LLPS-Aon-3876Aotus nancymaae88.240.0 835
LLPS-Mam-3127Macaca mulatta88.240.0 841
LLPS-Nol-3782Nomascus leucogenys88.240.0 836
LLPS-Caj-3922Callithrix jacchus87.690.0 847
LLPS-Ova-3555Ovis aries87.640.0 835
LLPS-Rhb-4794Rhinopithecus bieti86.630.0 669
LLPS-Bot-3663Bos taurus86.390.0 860
LLPS-Fec-1617Felis catus86.180.0 837
LLPS-Tut-0206Tursiops truncatus85.530.0 836
LLPS-Otg-3997Otolemur garnettii85.230.0 822
LLPS-Myl-3607Myotis lucifugus84.960.0 666
LLPS-Sus-1059Sus scrofa84.670.0 823
LLPS-Cas-2636Carlito syrichta84.230.0 817
LLPS-Fud-0313Fukomys damarensis83.170.0 726
LLPS-Aim-2623Ailuropoda melanoleuca83.150.0 812
LLPS-Loa-0408Loxodonta africana83.150.0 826
LLPS-Orc-3147Oryctolagus cuniculus83.150.0 788
LLPS-Cap-1129Cavia porcellus82.540.0 787
LLPS-Ict-3121Ictidomys tridecemlineatus82.081e-49 174
LLPS-Mup-1375Mustela putorius furo81.470.0 785
LLPS-Caf-2063Canis familiaris80.180.0 753
LLPS-Dio-3208Dipodomys ordii79.910.0 800
LLPS-Mea-2052Mesocricetus auratus77.20.0 731
LLPS-Mum-3053Mus musculus76.240.0 731
LLPS-Ran-3587Rattus norvegicus76.030.0 718
LLPS-Ten-1208Tetraodon nigroviridis74.853e-84 268
LLPS-Ora-2159Ornithorhynchus anatinus74.820.0 657
LLPS-Fia-0490Ficedula albicollis72.170.0 638
LLPS-Anp-2532Anas platyrhynchos72.060.0 636
LLPS-Sah-0708Sarcophilus harrisii71.310.0 696
LLPS-Tag-3120Taeniopygia guttata71.080.0 633
LLPS-Anc-1030Anolis carolinensis70.460.0 657
LLPS-Pes-3005Pelodiscus sinensis70.320.0 691
LLPS-Meg-2114Meleagris gallopavo70.210.0 643
LLPS-Mod-0098Monodelphis domestica69.040.0 663
LLPS-Gaga-2592Gallus gallus69.030.0 681
LLPS-Lac-4034Latimeria chalumnae67.040.0 657
LLPS-Leo-3182Lepisosteus oculatus66.520.0 665
LLPS-Scf-0560Scleropages formosus66.450.0 634
LLPS-Gaa-1738Gasterosteus aculeatus65.390.0 578
LLPS-Asm-2978Astyanax mexicanus65.040.0 630
LLPS-Icp-3187Ictalurus punctatus64.490.0 624
LLPS-Pof-0280Poecilia formosa63.640.0 571
LLPS-Xim-1642Xiphophorus maculatus63.410.0 566
LLPS-Orn-2790Oreochromis niloticus63.160.0 609
LLPS-Scm-2643Scophthalmus maximus63.040.0 611
LLPS-Orl-1886Oryzias latipes62.830.0 610
LLPS-Xet-0520Xenopus tropicalis62.450.0 605
LLPS-Dar-0476Danio rerio62.420.0 607
LLPS-Tar-0721Takifugu rubripes61.870.0 595
LLPS-Cii-1343Ciona intestinalis61.784e-81 261
LLPS-Cis-0809Ciona savignyi49.165e-154 459
LLPS-Chr-1672Chlamydomonas reinhardtii38.264e-29 125
LLPS-Sob-0890Sorghum bicolor38.182e-26 117
LLPS-Php-2083Physcomitrella patens38.053e-32 132
LLPS-Orbr-1046Oryza brachyantha37.734e-26 115
LLPS-Hea-2339Helianthus annuus37.242e-27 119
LLPS-Cae-0273Caenorhabditis elegans37.234e-30 125
LLPS-Sol-0896Solanum lycopersicum36.845e-34 137
LLPS-Zem-1154Zea mays36.822e-25 114
LLPS-Brd-1197Brachypodium distachyon36.652e-24 110
LLPS-Brr-0991Brassica rapa36.482e-26 116
LLPS-Bro-2962Brassica oleracea36.452e-26 117
LLPS-Amt-1969Amborella trichopoda36.332e-25 114
LLPS-Sot-1254Solanum tuberosum36.01e-29 122
LLPS-Thc-0125Theobroma cacao35.921e-25 114
LLPS-Lep-1368Leersia perrieri35.911e-24 111
LLPS-Gor-2382Gossypium raimondii35.781e-25 114
LLPS-Arl-2940Arabidopsis lyrata35.022e-24 110
LLPS-Orb-1387Oryza barthii34.172e-25 112
LLPS-Orni-2302Oryza nivara34.172e-25 112
LLPS-Orr-0916Oryza rufipogon34.172e-25 112
LLPS-Viv-2158Vitis vinifera33.912e-28 121
LLPS-Mua-1788Musa acuminata33.653e-27 119
LLPS-Urm-2222Ursus maritimus33.337e-28 119
LLPS-Art-2536Arabidopsis thaliana33.333e-36 143
LLPS-Ere-0455Erinaceus europaeus33.191e-25 112
LLPS-Via-0196Vigna angularis33.112e-29 125
LLPS-Met-2649Medicago truncatula33.061e-26 115
LLPS-Phv-1276Phaseolus vulgaris32.899e-28 120
LLPS-Prp-2103Prunus persica32.792e-35 141
LLPS-Vir-1967Vigna radiata32.442e-36 144
LLPS-Brn-1288Brassica napus32.333e-28 122
LLPS-Sem-1761Selaginella moellendorffii32.331e-35 141
LLPS-Glm-2281Glycine max32.258e-36 142
LLPS-Dac-2443Daucus carota32.122e-39 152
LLPS-Sei-1110Setaria italica32.097e-26 115
LLPS-Orgl-1777Oryza glumaepatula31.873e-32 132
LLPS-Coc-1967Corchorus capsularis31.723e-30 126
LLPS-Pot-2451Populus trichocarpa31.511e-25 114
LLPS-Nia-1091Nicotiana attenuata31.482e-34 138
LLPS-Cus-2120Cucumis sativus31.195e-32 131
LLPS-Mae-1585Manihot esculenta31.152e-31 130
LLPS-Drm-0936Drosophila melanogaster30.597e-26 114
LLPS-Hov-1319Hordeum vulgare30.482e-32 132
LLPS-Tra-0847Triticum aestivum30.284e-34 137
LLPS-Tru-1918Triticum urartu30.223e-29 123
LLPS-Ori-1742Oryza indica30.092e-35 141
LLPS-Orp-1183Oryza punctata29.512e-34 138