LLPS-Eqc-1778
TSFM
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Elongation factor Ts, mitochondrial |
| Gene Name: | TSFM |
| Ensembl Gene: | ENSECAG00000010520.2 |
| Ensembl Protein: | ENSECAP00000008458.2 |
| Organism: | Equus caballus |
| Taxa ID: | 9796 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSECAT00000010899.2 | ENSECAP00000008458.2 |
| UniProt | F6SMB0, F6SMB0_HORSE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSLLRALRLC LVARPRRCPR RGLGPSSDLP FSVMHLPLPP TPIRLHPSPP PPSLPLRGPA 60 61 LEGPLLLQSP EPWHSFHAGR WLSSSASSKE LLMKLRRKTG YAFVNCKKAL EACGGDLKKA 120 121 ESWLHKQAQK EGWSKAAKLH GRKTKEGLIG LLQEGNTTVL VEVNCETDFV SRNLKFQQLV 180 181 QQVALGTMLH CQSLKDQLSS YSKGFLNSSE LSELPAGPET EGFLKDQLAL AIGKLGENMS 240 241 LKRAAWVKVP AGFFVGSYVH GAMHSPSLHN LVLGKYGALV VCETSEQRAD LEDLGRRLGQ 300 301 HVVGMAPLSV GSLDDEPGGE AETKMLSQPY LLDPSITLGQ YVEPHGVSVV DFVRFECGEG 360 361 EEAAEAE 367 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCGCTGC TGCGAGCTCT GCGCCTCTGC CTGGTCGCGC GGCCCCGGCG CTGCCCGCGG 60 61 AGGGGGCTTG GCCCCAGCAG CGACCTGCCT TTCTCTGTGA TGCACCTTCC CCTTCCTCCA 120 121 ACCCCCATTC GACTCCATCC CTCCCCTCCC CCGCCCTCAT TGCCTCTGCG AGGTCCAGCC 180 181 CTGGAGGGGC CTCTTTTGCT TCAGTCGCCC GAGCCATGGC ACTCATTTCA TGCCGGGCGC 240 241 TGGCTGTCTT CCTCGGCCTC CAGCAAGGAG CTCCTCATGA AGCTGCGGCG AAAAACGGGC 300 301 TACGCCTTTG TAAACTGCAA GAAAGCTCTG GAGGCTTGTG GCGGGGATCT CAAAAAGGCA 360 361 GAGAGCTGGC TCCATAAGCA GGCCCAGAAG GAGGGCTGGA GCAAAGCTGC CAAGCTCCAT 420 421 GGGAGAAAGA CTAAAGAAGG GCTGATTGGG CTGCTGCAGG AAGGAAACAC GACAGTGCTA 480 481 GTAGAGGTAA ACTGTGAGAC AGATTTTGTT TCCAGAAATT TGAAATTTCA GCAGTTGGTC 540 541 CAGCAAGTAG CCCTTGGAAC CATGTTGCAT TGTCAGAGCC TAAAGGATCA ACTCTCCTCG 600 601 TACAGTAAAG GTTTCTTGAA TTCCTCTGAG CTCTCTGAAC TTCCAGCTGG CCCTGAGACG 660 661 GAAGGCTTTC TCAAGGATCA GCTGGCCTTA GCAATCGGGA AACTGGGAGA AAACATGAGT 720 721 CTTAAACGAG CTGCATGGGT GAAGGTGCCA GCTGGGTTCT TTGTTGGCTC TTATGTCCAC 780 781 GGAGCGATGC ACAGTCCCTC ACTCCACAAC CTGGTGCTGG GGAAGTACGG GGCGCTGGTC 840 841 GTCTGCGAGA CGTCGGAGCA GAGGGCAGAC CTGGAGGACC TTGGCCGCCG CCTTGGGCAG 900 901 CATGTGGTGG GCATGGCCCC GCTCTCTGTT GGCTCCCTGG ATGATGAGCC TGGGGGAGAG 960 961 GCGGAAACCA AGATGCTGTC CCAGCCATAT TTGCTGGATC CTTCCATCAC ATTGGGACAG 1020 1021 TATGTGGAGC CCCACGGGGT GTCTGTGGTA GACTTTGTGC GGTTTGAATG TGGAGAAGGC 1080 1081 GAAGAGGCAG CAGAAGCTGA ATAG 1104 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mitochondrial matrix | |
Cellular Component | Nucleus | |
Molecular Function | Translation elongation factor activity | |
Biological Process | Mitochondrial translational elongation | |
Biological Process | Regulation of mitochondrial translation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Aim-0042 | Ailuropoda melanoleuca | 93.17 | 0.0 | 564 |
| LLPS-Tut-2438 | Tursiops truncatus | 92.83 | 0.0 | 565 |
| LLPS-Urm-2429 | Ursus maritimus | 92.15 | 0.0 | 557 |
| LLPS-Mup-1679 | Mustela putorius furo | 91.81 | 0.0 | 558 |
| LLPS-Fec-3325 | Felis catus | 90.78 | 0.0 | 551 |
| LLPS-Caf-4274 | Canis familiaris | 90.71 | 0.0 | 522 |
| LLPS-Ova-2313 | Ovis aries | 90.69 | 0.0 | 526 |
| LLPS-Bot-3501 | Bos taurus | 90.69 | 0.0 | 525 |
| LLPS-Sus-2193 | Sus scrofa | 90.44 | 0.0 | 539 |
| LLPS-Ict-0859 | Ictidomys tridecemlineatus | 89.76 | 0.0 | 527 |
| LLPS-Dio-3234 | Dipodomys ordii | 89.41 | 3e-153 | 439 |
| LLPS-Myl-4176 | Myotis lucifugus | 89.4 | 0.0 | 525 |
| LLPS-Chs-2991 | Chlorocebus sabaeus | 89.08 | 0.0 | 540 |
| LLPS-Loa-2612 | Loxodonta africana | 88.74 | 0.0 | 540 |
| LLPS-Poa-1337 | Pongo abelii | 88.4 | 0.0 | 532 |
| LLPS-Otg-0035 | Otolemur garnettii | 87.29 | 0.0 | 525 |
| LLPS-Cap-0860 | Cavia porcellus | 86.73 | 0.0 | 524 |
| LLPS-Cas-1044 | Carlito syrichta | 86.29 | 3e-149 | 430 |
| LLPS-Mum-4756 | Mus musculus | 85.57 | 0.0 | 516 |
| LLPS-Fud-1945 | Fukomys damarensis | 85.32 | 0.0 | 519 |
| LLPS-Mea-3399 | Mesocricetus auratus | 84.83 | 3e-176 | 500 |
| LLPS-Caj-1850 | Callithrix jacchus | 84.46 | 3e-178 | 506 |
| LLPS-Rhb-4754 | Rhinopithecus bieti | 83.44 | 0.0 | 529 |
| LLPS-Nol-1549 | Nomascus leucogenys | 83.44 | 0.0 | 527 |
| LLPS-Aon-3919 | Aotus nancymaae | 82.8 | 0.0 | 522 |
| LLPS-Man-2079 | Macaca nemestrina | 82.48 | 0.0 | 525 |
| LLPS-Mam-2501 | Macaca mulatta | 82.48 | 0.0 | 525 |
| LLPS-Cea-3466 | Cercocebus atys | 82.48 | 0.0 | 525 |
| LLPS-Maf-3806 | Macaca fascicularis | 82.48 | 0.0 | 525 |
| LLPS-Mal-1014 | Mandrillus leucophaeus | 82.48 | 0.0 | 525 |
| LLPS-Gog-3197 | Gorilla gorilla | 82.17 | 0.0 | 518 |
| LLPS-Paa-1274 | Papio anubis | 82.17 | 0.0 | 523 |
| LLPS-Hos-1095 | Homo sapiens | 81.85 | 0.0 | 516 |
| LLPS-Pat-2073 | Pan troglodytes | 81.85 | 0.0 | 517 |
| LLPS-Pap-2554 | Pan paniscus | 81.85 | 0.0 | 517 |
| LLPS-Mod-1883 | Monodelphis domestica | 80.74 | 1e-161 | 464 |
| LLPS-Orc-3647 | Oryctolagus cuniculus | 80.2 | 9e-167 | 480 |
| LLPS-Ere-0988 | Erinaceus europaeus | 78.44 | 4e-84 | 260 |
| LLPS-Ran-4593 | Rattus norvegicus | 78.12 | 2e-144 | 419 |
| LLPS-Sah-3620 | Sarcophilus harrisii | 76.61 | 4e-164 | 470 |
| LLPS-Pes-0623 | Pelodiscus sinensis | 70.5 | 9e-96 | 291 |
| LLPS-Anc-3619 | Anolis carolinensis | 65.38 | 5e-127 | 375 |
| LLPS-Xet-3696 | Xenopus tropicalis | 64.23 | 3e-129 | 379 |
| LLPS-Lac-2856 | Latimeria chalumnae | 62.91 | 5e-124 | 368 |
| LLPS-Tar-3396 | Takifugu rubripes | 54.96 | 6e-92 | 285 |
| LLPS-Ten-3407 | Tetraodon nigroviridis | 54.44 | 1e-89 | 279 |
| LLPS-Scf-3547 | Scleropages formosus | 54.41 | 1e-94 | 291 |
| LLPS-Gaga-2355 | Gallus gallus | 54.05 | 3e-16 | 84.0 |
| LLPS-Scm-2819 | Scophthalmus maximus | 53.19 | 6e-93 | 287 |
| LLPS-Orl-1332 | Oryzias latipes | 53.0 | 7e-89 | 277 |
| LLPS-Pof-0531 | Poecilia formosa | 52.69 | 5e-84 | 265 |
| LLPS-Asm-2332 | Astyanax mexicanus | 52.38 | 8e-90 | 279 |
| LLPS-Xim-0068 | Xiphophorus maculatus | 52.28 | 1e-91 | 284 |
| LLPS-Dar-1663 | Danio rerio | 51.09 | 6e-88 | 275 |
| LLPS-Gaa-1916 | Gasterosteus aculeatus | 50.0 | 2e-88 | 276 |
| LLPS-Orn-0993 | Oreochromis niloticus | 48.07 | 5e-81 | 257 |
| LLPS-Cus-0369 | Cucumis sativus | 47.31 | 5e-15 | 80.9 |
| LLPS-Thc-1722 | Theobroma cacao | 46.88 | 7e-16 | 83.2 |
| LLPS-Hea-0826 | Helianthus annuus | 45.83 | 1e-14 | 79.7 |
| LLPS-Lep-0575 | Leersia perrieri | 45.83 | 5e-16 | 84.0 |
| LLPS-Coc-1063 | Corchorus capsularis | 45.54 | 5e-15 | 80.9 |
| LLPS-Glm-2242 | Glycine max | 45.54 | 2e-15 | 81.6 |
| LLPS-Via-1162 | Vigna angularis | 45.54 | 3e-15 | 81.3 |
| LLPS-Mae-1062 | Manihot esculenta | 45.45 | 1e-14 | 79.7 |
| LLPS-Pot-2022 | Populus trichocarpa | 45.45 | 5e-16 | 84.0 |
| LLPS-Viv-2487 | Vitis vinifera | 45.45 | 1e-14 | 79.7 |
| LLPS-Met-2306 | Medicago truncatula | 45.45 | 3e-16 | 84.3 |
| LLPS-Sei-1371 | Setaria italica | 45.45 | 2e-16 | 85.1 |
| LLPS-Phv-0241 | Phaseolus vulgaris | 45.19 | 1e-15 | 82.8 |
| LLPS-Gor-0972 | Gossypium raimondii | 44.79 | 3e-15 | 81.3 |
| LLPS-Orbr-1918 | Oryza brachyantha | 44.55 | 2e-14 | 79.3 |
| LLPS-Orp-1179 | Oryza punctata | 44.23 | 3e-16 | 84.3 |
| LLPS-Sot-0655 | Solanum tuberosum | 44.12 | 1e-15 | 82.4 |
| LLPS-Bro-0418 | Brassica oleracea | 43.69 | 1e-16 | 85.5 |
| LLPS-Brn-1634 | Brassica napus | 43.69 | 2e-16 | 85.1 |
| LLPS-Amt-1012 | Amborella trichopoda | 43.56 | 2e-13 | 75.5 |
| LLPS-Ors-0552 | Oryza sativa | 43.27 | 8e-15 | 80.1 |
| LLPS-Orm-1521 | Oryza meridionalis | 43.27 | 6e-15 | 80.5 |
| LLPS-Orr-1873 | Oryza rufipogon | 43.27 | 8e-15 | 80.1 |
| LLPS-Orni-0086 | Oryza nivara | 43.27 | 8e-15 | 80.1 |
| LLPS-Dac-1536 | Daucus carota | 43.27 | 3e-14 | 78.2 |
| LLPS-Orb-1164 | Oryza barthii | 43.27 | 9e-15 | 80.1 |
| LLPS-Ori-0332 | Oryza indica | 43.27 | 8e-15 | 80.1 |
| LLPS-Orgl-0672 | Oryza glumaepatula | 43.27 | 8e-15 | 80.1 |
| LLPS-Sol-0618 | Solanum lycopersicum | 43.14 | 7e-15 | 80.1 |
| LLPS-Chr-1629 | Chlamydomonas reinhardtii | 42.99 | 8e-13 | 73.9 |
| LLPS-Art-1437 | Arabidopsis thaliana | 42.73 | 6e-17 | 86.7 |
| LLPS-Prp-2018 | Prunus persica | 42.71 | 3e-14 | 78.6 |
| LLPS-Mua-0208 | Musa acuminata | 42.71 | 6e-13 | 74.3 |
| LLPS-Nia-1611 | Nicotiana attenuata | 42.59 | 2e-15 | 82.0 |
| LLPS-Php-1962 | Physcomitrella patens | 42.57 | 5e-14 | 77.8 |
| LLPS-Tru-1284 | Triticum urartu | 42.42 | 2e-14 | 78.6 |
| LLPS-Tra-2689 | Triticum aestivum | 42.42 | 2e-14 | 78.6 |
| LLPS-Zem-2029 | Zea mays | 42.31 | 7e-16 | 83.2 |
| LLPS-Leo-3636 | Lepisosteus oculatus | 41.84 | 3e-53 | 184 |
| LLPS-Chc-0081 | Chondrus crispus | 41.49 | 8e-11 | 65.1 |
| LLPS-Brd-0188 | Brachypodium distachyon | 40.38 | 2e-14 | 79.0 |
| LLPS-Sem-2042 | Selaginella moellendorffii | 40.19 | 5e-14 | 77.4 |
| LLPS-Drm-2179 | Drosophila melanogaster | 40.07 | 2e-50 | 177 |
| LLPS-Hov-0480 | Hordeum vulgare | 40.0 | 9e-15 | 80.1 |
| LLPS-Icp-3930 | Ictalurus punctatus | 39.73 | 2e-50 | 176 |
| LLPS-Sob-0447 | Sorghum bicolor | 39.32 | 2e-15 | 81.6 |
| LLPS-Osl-0732 | Ostreococcus lucimarinus | 38.82 | 7e-09 | 61.2 |
| LLPS-Cis-1285 | Ciona savignyi | 34.09 | 9e-30 | 119 |
| LLPS-Cae-0900 | Caenorhabditis elegans | 33.67 | 1e-43 | 159 |
| LLPS-Cii-0372 | Ciona intestinalis | 32.79 | 3e-45 | 164 |
| LLPS-Abg-0637 | Absidia glauca | 31.63 | 2e-27 | 115 |
| LLPS-Cym-0158 | Cyanidioschyzon merolae | 29.23 | 1e-10 | 64.3 |
| LLPS-Gas-0001 | Galdieria sulphuraria | 28.23 | 6e-12 | 70.1 |
| LLPS-Vir-0485 | Vigna radiata | 28.21 | 5e-12 | 70.1 |
| LLPS-Org-2082 | Oryza glaberrima | 28.0 | 4e-14 | 76.6 |
| LLPS-Crn-0957 | Cryptococcus neoformans | 27.15 | 9e-15 | 79.0 |
| LLPS-Scj-1513 | Schizosaccharomyces japonicus | 27.03 | 7e-12 | 69.7 |
| LLPS-Arl-1068 | Arabidopsis lyrata | 26.69 | 1e-11 | 69.7 |
| LLPS-Miv-1414 | Microbotryum violaceum | 26.54 | 1e-16 | 84.7 |
| LLPS-Brr-2111 | Brassica rapa | 26.46 | 3e-10 | 65.1 |
| LLPS-Scc-0950 | Schizosaccharomyces cryophilus | 26.43 | 1e-16 | 83.2 |
| LLPS-Scp-0542 | Schizosaccharomyces pombe | 25.6 | 5e-11 | 67.0 |