• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-1491
PRPF6

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Pre-mRNA processing factor 6
Gene Name: PRPF6
Ensembl Gene: ENSECAG00000013983.2
Ensembl Protein: ENSECAP00000012194.2
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, NucleolusPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSECAT00000015195.2ENSECAP00000012194.2
UniProtF7C1V1, F7C1V1_HORSE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNKKKKPFLG  MPAPLGYVPG  LGRGATGFTT  RSDIGPARDA  NDPVDDRHAP  PGKRTVGDQM  60
61    KKSQAADDDD  EDLNDTNYDE  FNGYAGSLFS  SGPYEKDDEE  ADAIYAALDK  RMDERRKERR  120
121   EQREKEEIEK  YRMERPKIQQ  QFSDLKRKLA  EVTEEEWLSI  PEVGDARNKR  QRNPRYEKLT  180
181   PVPDSFFAKH  LQTGENHTSV  DPRQTQFGGL  NTPYPGGLNT  PYPGGMTPGL  MTPGTGELDM  240
241   RKIGQARNTL  MDMRLSQVSD  SVSGQTVVDP  KGYLTDLNSM  IPTHGGDIND  IKKARLLLKS  300
301   VRETNPHHPP  AWIASARLEE  VTGKLQVARN  LIMKGTEMCP  KSEDVWLEAA  RLQPGDTAKA  360
361   VVAQAVRHLP  QSVRIYIRAA  ELETDIRAKK  RVLRKALEHV  PNSVRLWKAA  VELEEPEDAR  420
421   IMLSRAVECC  PTSVELWLAL  ARLETYENAR  KVLNKARENI  PTDRHIWITA  AKLEEANGNT  480
481   QMVEKIIDRA  ITSLRANGVE  INREQWIQDA  EECDKAGSVA  TCQAVMRAVI  GIGIEEEDRK  540
541   HTWMEDADSC  VAHNALECAR  AIYAYALQVF  PSKKSVWLRA  AYFEKNHGTR  ESLEALLQRA  600
601   VAHCPKAEVL  WLMGAKSKWL  AGDVPAARSI  LALAFQVFMK  SVKLEWVLGN  IAAAQELCEE  660
661   ALKHYEDFPK  LWMMKGQIEE  QEELTEKARE  AYNQGLKKCP  HSTPLWLLLS  RLEEKIGQLT  720
721   RARAILEKSR  LKNPKNPGLW  LESVRLEYRA  GLKNIANTLM  AKALQECPSS  GVLWSEAIFL  780
781   EARPQRKTKS  VDALKKCEHD  PHVLLAVAKL  FWSERKITKA  REWFLRTVKI  DSDLGDAWAL  840
841   FYKFELQHGT  EEQREEVRRR  CENAEPRHGE  LWCAVSKDIA  NWQRKIGEIL  VLVAARIKNT  900
901   F  901
Nucleotide CDS Sequence (FASTA)
1     ATGAACAAGA  AGAAGAAGCC  GTTCCTGGGC  ATGCCCGCGC  CGCTCGGCTA  CGTGCCGGGC  60
61    CTGGGCCGGG  GTGCCACTGG  CTTTACCACC  CGGTCGGACA  TTGGGCCTGC  CCGGGATGCA  120
121   AATGATCCTG  TGGATGACCG  CCATGCACCC  CCCGGCAAGA  GAACTGTCGG  GGACCAGATG  180
181   AAGAAAAGCC  AGGCTGCGGA  TGATGACGAC  GAGGATCTGA  ATGACACCAA  CTATGACGAG  240
241   TTTAATGGCT  ATGCCGGGAG  CCTCTTCTCA  AGTGGGCCCT  ACGAGAAAGA  TGATGAGGAA  300
301   GCAGATGCTA  TTTATGCAGC  TCTGGATAAA  AGGATGGATG  AAAGAAGAAA  AGAAAGAAGG  360
361   GAGCAAAGGG  AGAAAGAAGA  AATTGAGAAA  TACCGCATGG  AACGCCCCAA  AATCCAACAA  420
421   CAGTTTTCAG  ATCTCAAAAG  GAAGTTGGCA  GAAGTCACAG  AAGAAGAGTG  GCTTAGCATC  480
481   CCTGAGGTTG  GCGATGCCAG  AAACAAACGC  CAGCGGAACC  CGCGCTATGA  GAAGCTGACC  540
541   CCTGTTCCTG  ACAGTTTCTT  TGCCAAACAT  TTACAGACTG  GAGAGAACCA  TACTTCAGTG  600
601   GATCCTCGAC  AAACTCAATT  TGGAGGTCTT  AACACACCCT  ATCCAGGTGG  ACTGAATACT  660
661   CCATACCCAG  GTGGAATGAC  ACCTGGATTG  ATGACACCTG  GCACAGGTGA  GCTGGACATG  720
721   AGGAAGATCG  GCCAAGCGAG  AAACACTTTG  ATGGACATGA  GGCTGAGCCA  GGTGTCTGAC  780
781   TCGGTGAGTG  GACAGACTGT  GGTCGACCCC  AAAGGCTATC  TGACGGATTT  AAATTCCATG  840
841   ATCCCAACCC  ATGGAGGGGA  CATCAATGAT  ATCAAGAAGG  CACGACTGCT  CCTCAAGTCT  900
901   GTTCGGGAGA  CAAACCCTCA  TCACCCACCA  GCCTGGATTG  CATCAGCCCG  CCTGGAGGAA  960
961   GTCACTGGGA  AGCTGCAAGT  AGCTAGAAAC  CTTATTATGA  AGGGGACGGA  GATGTGCCCC  1020
1021  AAGAGTGAAG  ATGTCTGGCT  AGAAGCAGCC  AGGTTGCAGC  CTGGGGATAC  GGCCAAGGCC  1080
1081  GTGGTGGCCC  AAGCGGTTCG  TCACCTCCCA  CAGTCTGTTA  GGATTTACAT  CAGAGCAGCA  1140
1141  GAGCTGGAAA  CGGACATCCG  AGCCAAGAAG  CGGGTGCTTC  GGAAGGCCCT  TGAGCATGTT  1200
1201  CCAAACTCGG  TTCGCTTGTG  GAAGGCGGCT  GTTGAGCTGG  AAGAGCCCGA  AGACGCTAGA  1260
1261  ATCATGCTTA  GCCGAGCTGT  GGAGTGCTGC  CCCACCAGCG  TGGAGCTCTG  GCTTGCTCTG  1320
1321  GCGAGGCTGG  AGACCTACGA  AAATGCCCGC  AAGGTCTTAA  ATAAGGCCCG  TGAGAACATC  1380
1381  CCTACAGACC  GGCACATCTG  GATCACGGCT  GCCAAGCTGG  AGGAAGCCAA  TGGAAATACG  1440
1441  CAGATGGTGG  AGAAAATCAT  TGATCGTGCC  ATCACTTCCC  TGCGGGCCAA  TGGTGTGGAG  1500
1501  ATCAACCGTG  AGCAGTGGAT  CCAGGATGCC  GAGGAGTGTG  ACAAGGCTGG  GAGTGTGGCC  1560
1561  ACCTGCCAGG  CGGTCATGCG  TGCCGTGATT  GGTATTGGGA  TTGAGGAGGA  GGATCGGAAG  1620
1621  CACACCTGGA  TGGAAGATGC  CGACAGTTGT  GTGGCCCACA  ACGCCCTGGA  GTGTGCGCGA  1680
1681  GCCATCTATG  CCTACGCCCT  GCAAGTGTTC  CCCAGCAAGA  AGAGTGTGTG  GCTGCGGGCT  1740
1741  GCGTACTTCG  AGAAGAACCA  TGGCACCAGG  GAGTCCCTGG  AAGCACTCTT  GCAGAGGGCC  1800
1801  GTGGCCCATT  GTCCCAAAGC  GGAGGTGCTG  TGGCTCATGG  GCGCCAAGTC  CAAGTGGCTG  1860
1861  GCAGGGGATG  TGCCGGCGGC  AAGGAGCATC  CTGGCCCTGG  CCTTCCAGGT  GTTCATGAAG  1920
1921  TCTGTGAAGC  TGGAGTGGGT  GCTTGGGAAC  ATCGCGGCTG  CCCAGGAGCT  GTGTGAGGAG  1980
1981  GCCCTGAAGC  ACTACGAGGA  CTTCCCCAAG  CTGTGGATGA  TGAAAGGGCA  GATCGAGGAG  2040
2041  CAGGAAGAGC  TGACAGAGAA  GGCTCGGGAG  GCCTACAACC  AGGGGTTGAA  GAAATGTCCC  2100
2101  CATTCCACAC  CCCTGTGGCT  TTTGCTTTCC  CGGCTGGAGG  AGAAGATTGG  ACAGCTGACC  2160
2161  CGAGCTCGGG  CCATTTTGGA  GAAGTCTCGC  CTGAAGAACC  CGAAGAACCC  TGGCCTGTGG  2220
2221  TTGGAGTCAG  TGAGGCTGGA  GTACCGTGCG  GGCCTGAAGA  ACATTGCCAA  CACACTCATG  2280
2281  GCCAAGGCGC  TGCAGGAGTG  CCCCAGCTCT  GGTGTCCTGT  GGTCTGAAGC  CATCTTCCTC  2340
2341  GAGGCAAGGC  CCCAGAGGAA  GACCAAGAGT  GTCGATGCCC  TGAAGAAGTG  TGAGCATGAC  2400
2401  CCCCATGTGC  TGCTGGCTGT  GGCCAAGCTG  TTCTGGAGTG  AGCGGAAGAT  CACCAAGGCC  2460
2461  AGGGAGTGGT  TCCTCCGCAC  GGTGAAGATC  GACTCGGACC  TGGGGGACGC  CTGGGCACTC  2520
2521  TTCTACAAGT  TCGAGCTGCA  GCATGGCACG  GAGGAGCAGC  GGGAGGAGGT  GAGGAGGCGC  2580
2581  TGTGAGAACG  CTGAGCCGCG  GCACGGGGAG  CTATGGTGTG  CCGTGTCCAA  GGACATCGCC  2640
2641  AACTGGCAGA  GGAAGATCGG  GGAGATCCTC  GTACTGGTGG  CAGCCCGCAT  CAAGAACACC  2700
2701  TTCTGA  2706

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Caf-2265Canis familiaris94.90.01665
LLPS-Bot-2975Bos taurus94.790.01664
LLPS-Sus-0130Sus scrofa94.790.01664
LLPS-Cap-1708Cavia porcellus94.370.01662
LLPS-Ova-0639Ovis aries94.370.01649
LLPS-Mod-0298Monodelphis domestica94.330.01426
LLPS-Mum-0466Mus musculus94.260.01661
LLPS-Mea-1240Mesocricetus auratus94.260.01660
LLPS-Fud-1694Fukomys damarensis94.220.01610
LLPS-Tut-1550Tursiops truncatus94.160.01652
LLPS-Ran-0261Rattus norvegicus94.160.01659
LLPS-Sah-0957Sarcophilus harrisii94.160.01660
LLPS-Cas-2141Carlito syrichta94.050.01657
LLPS-Mup-0817Mustela putorius furo93.980.01459
LLPS-Ora-2773Ornithorhynchus anatinus93.940.01638
LLPS-Aim-1078Ailuropoda melanoleuca93.840.01633
LLPS-Fec-0699Felis catus93.810.01624
LLPS-Tag-2881Taeniopygia guttata93.620.01652
LLPS-Fia-0672Ficedula albicollis93.520.01650
LLPS-Pes-1762Pelodiscus sinensis93.420.01528
LLPS-Anc-0214Anolis carolinensis93.410.01625
LLPS-Aon-2558Aotus nancymaae93.410.01645
LLPS-Caj-1677Callithrix jacchus93.410.01645
LLPS-Meg-0387Meleagris gallopavo93.350.01597
LLPS-Gaga-0822Gallus gallus93.30.01646
LLPS-Loa-0413Loxodonta africana93.30.01643
LLPS-Hos-1428Homo sapiens93.30.01645
LLPS-Pat-3156Pan troglodytes93.30.01645
LLPS-Pap-0130Pan paniscus93.30.01645
LLPS-Gog-0022Gorilla gorilla93.30.01645
LLPS-Nol-1601Nomascus leucogenys93.20.01644
LLPS-Rhb-2667Rhinopithecus bieti93.20.01644
LLPS-Cea-0072Cercocebus atys93.20.01645
LLPS-Maf-0964Macaca fascicularis93.20.01644
LLPS-Dio-2827Dipodomys ordii92.990.01506
LLPS-Poa-3054Pongo abelii92.770.01631
LLPS-Paa-1808Papio anubis92.670.01635
LLPS-Orc-0552Oryctolagus cuniculus92.60.01607
LLPS-Urm-0232Ursus maritimus92.520.01591
LLPS-Ict-2250Ictidomys tridecemlineatus91.30.01630
LLPS-Xet-0224Xenopus tropicalis90.010.01605
LLPS-Leo-0394Lepisosteus oculatus89.90.01600
LLPS-Anp-0260Anas platyrhynchos89.560.0 967
LLPS-Scf-2266Scleropages formosus89.470.01567
LLPS-Icp-1686Ictalurus punctatus88.950.01576
LLPS-Chs-1180Chlorocebus sabaeus88.170.01525
LLPS-Asm-2025Astyanax mexicanus87.770.01567
LLPS-Dar-2380Danio rerio87.350.01571
LLPS-Mam-2153Macaca mulatta86.840.01472
LLPS-Xim-1857Xiphophorus maculatus86.820.01565
LLPS-Orl-0258Oryzias latipes86.720.01553
LLPS-Otg-0597Otolemur garnettii86.310.01456
LLPS-Scm-1096Scophthalmus maximus86.290.01538
LLPS-Pof-0964Poecilia formosa85.990.01563
LLPS-Orn-2400Oreochromis niloticus85.970.01550
LLPS-Gaa-1159Gasterosteus aculeatus85.840.01539
LLPS-Mal-0583Mandrillus leucophaeus85.770.01176
LLPS-Tar-3136Takifugu rubripes85.330.01546
LLPS-Man-4325Macaca nemestrina78.920.01300
LLPS-Ten-2055Tetraodon nigroviridis78.760.01399
LLPS-Cii-1141Ciona intestinalis70.30.01263
LLPS-Drm-0722Drosophila melanogaster67.060.01208
LLPS-Tru-0397Triticum urartu55.670.0 837
LLPS-Viv-1394Vitis vinifera53.940.0 887
LLPS-Prp-2081Prunus persica53.760.0 895
LLPS-Cus-0666Cucumis sativus53.620.0 892
LLPS-Orbr-0208Oryza brachyantha53.170.0 818
LLPS-Orgl-1990Oryza glumaepatula53.170.0 822
LLPS-Orb-1188Oryza barthii53.170.0 822
LLPS-Mae-0728Manihot esculenta53.030.0 887
LLPS-Sot-0245Solanum tuberosum52.960.0 899
LLPS-Gor-0682Gossypium raimondii52.940.0 875
LLPS-Sol-1111Solanum lycopersicum52.880.0 896
LLPS-Thc-0335Theobroma cacao52.770.0 881
LLPS-Nia-0359Nicotiana attenuata52.680.0 892
LLPS-Vir-0610Vigna radiata52.670.0 811
LLPS-Php-0035Physcomitrella patens52.590.0 880
LLPS-Orp-0894Oryza punctata52.540.0 858
LLPS-Lep-2271Leersia perrieri52.520.0 877
LLPS-Hea-0930Helianthus annuus52.510.0 871
LLPS-Cae-1441Caenorhabditis elegans52.480.0 937
LLPS-Hov-1063Hordeum vulgare52.410.0 865
LLPS-Pot-1150Populus trichocarpa52.390.0 870
LLPS-Zem-0193Zea mays52.320.0 858
LLPS-Sei-1662Setaria italica52.30.0 865
LLPS-Dac-0068Daucus carota52.270.0 872
LLPS-Coc-0982Corchorus capsularis52.220.0 867
LLPS-Orr-0787Oryza rufipogon52.20.0 858
LLPS-Ori-0161Oryza indica52.20.0 858
LLPS-Orm-1340Oryza meridionalis52.090.0 858
LLPS-Brd-0900Brachypodium distachyon52.090.0 858
LLPS-Orni-0182Oryza nivara52.090.0 855
LLPS-Phv-1500Phaseolus vulgaris52.050.0 870
LLPS-Via-0142Vigna angularis51.840.0 859
LLPS-Sob-0864Sorghum bicolor51.770.0 852
LLPS-Glm-2310Glycine max51.590.0 863
LLPS-Amt-1588Amborella trichopoda51.480.0 855
LLPS-Brr-0174Brassica rapa51.030.0 847
LLPS-Bro-0794Brassica oleracea50.920.0 845
LLPS-Art-0877Arabidopsis thaliana50.90.0 854
LLPS-Abg-0291Absidia glauca50.70.0 804
LLPS-Tra-0242Triticum aestivum50.650.0 815
LLPS-Sem-0064Selaginella moellendorffii50.520.0 831
LLPS-Arl-1772Arabidopsis lyrata50.430.0 828
LLPS-Brn-0742Brassica napus50.340.0 785
LLPS-Met-0731Medicago truncatula50.310.0 833
LLPS-Chr-0606Chlamydomonas reinhardtii50.050.0 785
LLPS-Map-0885Magnaporthe poae48.681e-62 216
LLPS-Ved-0999Verticillium dahliae48.578e-172 523
LLPS-Osl-0144Ostreococcus lucimarinus47.450.0 731
LLPS-Ors-0068Oryza sativa47.030.0 599
LLPS-Fuo-0676Fusarium oxysporum46.880.0 578
LLPS-Mua-1796Musa acuminata46.620.0 694
LLPS-Scs-0494Sclerotinia sclerotiorum46.040.0 728
LLPS-Cog-0748Colletotrichum gloeosporioides46.010.0 733
LLPS-Cogr-1014Colletotrichum graminicola45.980.0 731
LLPS-Miv-0934Microbotryum violaceum45.960.0 736
LLPS-Coo-0096Colletotrichum orbiculare45.430.0 718
LLPS-Cis-0933Ciona savignyi45.370.0 567
LLPS-Nef-0809Neosartorya fischeri45.090.0 727
LLPS-Tum-0471Tuber melanosporum45.010.0 646
LLPS-Asc-0463Aspergillus clavatus44.990.0 732
LLPS-Scj-0056Schizosaccharomyces japonicus44.890.0 742
LLPS-Scc-0496Schizosaccharomyces cryophilus44.760.0 746
LLPS-Blg-0125Blumeria graminis44.670.0 720
LLPS-Mel-0164Melampsora laricipopulina44.610.0 743
LLPS-Ast-0226Aspergillus terreus44.580.0 726
LLPS-Asf-0513Aspergillus flavus44.540.0 708
LLPS-Asfu-0401Aspergillus fumigatus44.50.0 698
LLPS-Pug-0765Puccinia graminis44.50.0 724
LLPS-Scp-0886Schizosaccharomyces pombe44.440.0 748
LLPS-Aso-0390Aspergillus oryzae44.430.0 707
LLPS-Fus-0722Fusarium solani44.40.0 678
LLPS-Fuv-0217Fusarium verticillioides44.350.0 684
LLPS-Asn-0708Aspergillus nidulans44.320.0 711
LLPS-Zyt-0634Zymoseptoria tritici44.190.0 717
LLPS-Asni-0278Aspergillus niger44.060.0 716
LLPS-Mao-0550Magnaporthe oryzae44.050.0 695
LLPS-Nec-0709Neurospora crassa43.780.0 658
LLPS-Crn-0931Cryptococcus neoformans43.780.0 709
LLPS-Beb-0783Beauveria bassiana43.590.0 663
LLPS-Trv-0472Trichoderma virens43.570.0 684
LLPS-Trr-0298Trichoderma reesei43.570.0 687
LLPS-Gag-0710Gaeumannomyces graminis43.460.0 692
LLPS-Dos-0851Dothistroma septosporum43.160.0 698
LLPS-Spr-1095Sporisorium reilianum42.280.0 643
LLPS-Gas-0945Galdieria sulphuraria42.010.0 684
LLPS-Usm-0091Ustilago maydis41.650.0 643
LLPS-Put-0456Puccinia triticina40.590.0 578
LLPS-Lem-0194Leptosphaeria maculans39.210.0 600
LLPS-Phn-0201Phaeosphaeria nodorum39.120.0 594
LLPS-Pyt-0556Pyrenophora teres39.060.0 585
LLPS-Pytr-0605Pyrenophora triticirepentis38.950.0 583
LLPS-Yal-0136Yarrowia lipolytica36.442e-155 486
LLPS-Asg-0040Ashbya gossypii27.385e-68 249
LLPS-Sac-1167Saccharomyces cerevisiae27.11e-82 291
LLPS-Kop-0751Komagataella pastoris26.61e-77 277
LLPS-Chc-1156Chondrus crispus24.718e-1892.0
LLPS-Myl-2235Myotis lucifugus23.865e-0757.8
LLPS-Cym-1127Cyanidioschyzon merolae23.122e-1482.0