• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-1411
GTF2H1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: General transcription factor IIH subunit 1
Gene Name: GTF2H1
Ensembl Gene: ENSECAG00000019056.2
Ensembl Protein: ENSECAP00000016804.2
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Cajal body, NucleolusPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKQAGSGGGG  RELAEGVMAA  ALWSHVPRRP  ALVLPVTCPQ  SSRRQRWRRD  PPVTEAVATA  60
61    AAAGFQPLPG  SVSRKRSGTQ  PNPAQFLTPC  PGPLLPPGQK  ISPEGKAKIQ  LQLVLHAGDT  120
121   TNFHFSNEST  AVKERDAVKD  LLQQLLPKFK  RKANKELEEK  NRMLQEDPVL  FQLYKDLVVS  180
181   QVISAEEFWA  NRLNGNAAES  SSTSNHKQDV  GISAAFLADV  RPQTDGCNGL  RYNLTSDIIE  240
241   SIFRTYPAVK  MKYAENVPHN  MTEKEFWTRF  FQSHYFHRDR  LNTGSKDLFA  ECAKIDEKGL  300
301   KTMVSLGVKN  PLLDLTALED  KPLDEGYGIS  SVPSTSNSKS  IKENSNAAII  KRFNHHSAMV  360
361   LAAGLRKQEA  QNEQNGEPSG  IDGNSGDADS  FQPAVKRAKL  QESIEYEDLG  KNNSIKTIAL  420
421   NLKKSDRYYH  GPTPIQSLQY  ATSQDIINSF  QSIRQEMEAY  APKLTQVLSS  SAASSTITAL  480
481   SPGGALMQGG  TQQAINQMVP  NDIQSELKHL  YVAVGELLRH  FWSCFPVNTP  FLEEKVVKMK  540
541   SNLERFQVTK  LCPFQEKIRR  QYLSTNLVSH  IEEMLQTAYN  KLHTWQSRRL  MKKT  594
Nucleotide CDS Sequence (FASTA)
1     ATGGCAACTT  CATCTGAAGA  AGTTCTGCTG  GTTGTGAAGA  AGGTGCGTCA  GAAGAAGCAG  60
61    GATGGAGCTC  TGTACCTCAT  GGCAGAAAGA  ATTGCCTGGG  CACCTGAAGG  CAAAGACAGA  120
121   TTTACAATCA  GCCATATGTA  TGCGGATATT  AAATGCCAGA  AAATCAGTCC  AGAAGGAAAA  180
181   GCTAAAATTC  AGCTTCAGCT  GGTCCTGCAT  GCAGGGGACA  CAACTAACTT  CCATTTTTCC  240
241   AATGAGAGCA  CAGCAGTGAA  AGAGCGGGAT  GCGGTGAAGG  ACCTCCTTCA  GCAGCTGCTG  300
301   CCCAAATTCA  AGAGGAAAGC  AAATAAAGAA  CTGGAGGAGA  AGAACAGAAT  GCTGCAAGAG  360
361   GATCCTGTTC  TGTTTCAGCT  TTATAAAGAC  CTTGTCGTGA  GTCAGGTGAT  CAGTGCTGAG  420
421   GAATTCTGGG  CCAATCGTTT  AAACGGGAAT  GCAGCGGAGA  GTTCTTCCAC  ATCTAATCAT  480
481   AAGCAGGATG  TTGGCATTTC  TGCAGCATTT  CTGGCTGATG  TCCGGCCCCA  AACAGATGGA  540
541   TGTAATGGTC  TGAGATACAA  TTTAACTTCT  GATATAATTG  AGTCCATATT  TAGGACCTAT  600
601   CCAGCAGTAA  AAATGAAATA  TGCAGAAAAT  GTTCCCCACA  ACATGACAGA  AAAGGAATTC  660
661   TGGACACGTT  TTTTTCAGTC  CCATTATTTT  CACAGGGACC  GGCTGAATAC  GGGGTCAAAG  720
721   GACCTCTTTG  CAGAATGTGC  CAAAATAGAT  GAAAAAGGGT  TAAAAACAAT  GGTTTCATTA  780
781   GGAGTGAAAA  ACCCACTACT  TGATTTGACA  GCTTTGGAAG  ATAAACCATT  AGATGAGGGC  840
841   TATGGCATTT  CCTCTGTGCC  ATCCACTTCT  AATTCTAAAT  CCATAAAGGA  GAATAGTAAT  900
901   GCTGCCATCA  TCAAGAGGTT  TAACCATCAC  AGTGCCATGG  TCCTGGCAGC  AGGTCTCAGG  960
961   AAACAAGAAG  CACAAAATGA  ACAAAATGGT  GAGCCCAGCG  GCATCGATGG  AAATTCCGGA  1020
1021  GATGCAGACA  GCTTTCAGCC  AGCAGTCAAA  AGGGCGAAGT  TACAAGAGTC  CATTGAATAT  1080
1081  GAAGACTTGG  GAAAAAATAA  TTCCATAAAA  ACGATTGCAC  TAAACCTCAA  GAAGTCAGAT  1140
1141  AGGTATTATC  ATGGTCCAAC  TCCAATCCAG  TCACTACAGT  ATGCAACAAG  TCAGGACATT  1200
1201  ATTAATTCTT  TTCAAAGTAT  TAGACAAGAA  ATGGAAGCTT  ATGCACCCAA  ATTAACTCAG  1260
1261  GTTCTCTCAA  GTAGCGCTGC  CAGTAGTACC  ATCACAGCCC  TGTCACCTGG  AGGAGCACTT  1320
1321  ATGCAGGGAG  GGACACAGCA  AGCCATAAAC  CAGATGGTGC  CAAATGATAT  TCAGTCTGAA  1380
1381  TTAAAACACC  TGTATGTGGC  TGTTGGGGAA  CTTCTGCGGC  ACTTCTGGTC  CTGCTTTCCC  1440
1441  GTTAATACAC  CATTCCTAGA  AGAAAAGGTA  GTGAAAATGA  AAAGTAATTT  GGAACGATTC  1500
1501  CAAGTTACAA  AGCTCTGCCC  ATTCCAAGAA  AAAATTCGGA  GACAGTATTT  AAGCACAAAT  1560
1561  TTGGTAAGTC  ACATAGAAGA  GATGCTCCAG  ACAGCCTATA  ACAAGCTCCA  CACGTGGCAG  1620
1621  TCACGGCGTC  TGATGAAGAA  AACGTGA  1647

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aim-0472Ailuropoda melanoleuca98.390.0 973
LLPS-Fec-1562Felis catus98.390.0 957
LLPS-Caf-0789Canis familiaris98.390.0 978
LLPS-Tut-1692Tursiops truncatus98.190.0 978
LLPS-Urm-1326Ursus maritimus98.190.0 972
LLPS-Ict-0146Ictidomys tridecemlineatus98.190.0 976
LLPS-Ova-0997Ovis aries97.980.0 975
LLPS-Bot-1909Bos taurus97.980.0 973
LLPS-Cas-3466Carlito syrichta97.980.0 974
LLPS-Caj-0240Callithrix jacchus97.780.0 954
LLPS-Gog-2946Gorilla gorilla97.780.0 954
LLPS-Cea-4532Cercocebus atys97.780.0 974
LLPS-Maf-0720Macaca fascicularis97.780.0 974
LLPS-Chs-3668Chlorocebus sabaeus97.780.0 974
LLPS-Mal-1439Mandrillus leucophaeus97.780.0 974
LLPS-Mup-0360Mustela putorius furo97.780.0 969
LLPS-Myl-2943Myotis lucifugus97.780.0 957
LLPS-Otg-2048Otolemur garnettii97.780.0 975
LLPS-Man-2633Macaca nemestrina97.780.0 974
LLPS-Hos-0215Homo sapiens97.780.0 973
LLPS-Pap-2388Pan paniscus97.780.0 973
LLPS-Nol-2160Nomascus leucogenys97.780.0 973
LLPS-Poa-0083Pongo abelii97.780.0 972
LLPS-Aon-1067Aotus nancymaae97.380.0 949
LLPS-Paa-4442Papio anubis97.380.0 969
LLPS-Rhb-1774Rhinopithecus bieti97.180.0 967
LLPS-Dio-1296Dipodomys ordii96.980.0 972
LLPS-Ran-2006Rattus norvegicus96.370.0 960
LLPS-Orc-0095Oryctolagus cuniculus96.370.0 965
LLPS-Loa-2758Loxodonta africana96.180.0 948
LLPS-Fud-1092Fukomys damarensis96.170.0 956
LLPS-Mum-2301Mus musculus96.170.0 957
LLPS-Mea-0754Mesocricetus auratus95.766e-149 436
LLPS-Cap-0716Cavia porcellus95.740.0 890
LLPS-Ere-0564Erinaceus europaeus95.060.0 793
LLPS-Sah-2956Sarcophilus harrisii93.160.0 925
LLPS-Ora-1946Ornithorhynchus anatinus92.643e-154 452
LLPS-Mod-0705Monodelphis domestica91.950.0 914
LLPS-Mam-2057Macaca mulatta91.530.0 894
LLPS-Sus-2124Sus scrofa91.370.0 957
LLPS-Pat-0144Pan troglodytes90.980.0 882
LLPS-Fia-3044Ficedula albicollis89.340.0 895
LLPS-Pes-1057Pelodiscus sinensis88.930.0 888
LLPS-Anp-2343Anas platyrhynchos88.930.0 893
LLPS-Gaga-1031Gallus gallus88.330.0 888
LLPS-Meg-0378Meleagris gallopavo87.930.0 885
LLPS-Anc-0285Anolis carolinensis87.930.0 858
LLPS-Tag-1400Taeniopygia guttata87.150.0 868
LLPS-Leo-0362Lepisosteus oculatus84.882e-40 150
LLPS-Xet-0736Xenopus tropicalis82.260.0 833
LLPS-Lac-2231Latimeria chalumnae80.120.0 785
LLPS-Icp-0641Ictalurus punctatus77.060.0 786
LLPS-Scf-2901Scleropages formosus77.060.0 790
LLPS-Orn-1226Oreochromis niloticus75.750.0 763
LLPS-Xim-0539Xiphophorus maculatus75.70.0 769
LLPS-Dar-3445Danio rerio75.70.0 769
LLPS-Pof-2209Poecilia formosa75.70.0 769
LLPS-Orl-0317Oryzias latipes75.550.0 762
LLPS-Asm-2308Astyanax mexicanus75.20.0 762
LLPS-Scm-1808Scophthalmus maximus74.90.0 761
LLPS-Tar-2323Takifugu rubripes74.70.0 758
LLPS-Ten-2768Tetraodon nigroviridis73.90.0 746
LLPS-Gaa-0858Gasterosteus aculeatus73.640.0 749
LLPS-Cii-0179Ciona intestinalis47.81e-140 427
LLPS-Cis-1042Ciona savignyi45.692e-132 405
LLPS-Drm-1614Drosophila melanogaster44.244e-142 432
LLPS-Lep-0950Leersia perrieri41.61e-2099.8
LLPS-Orni-0241Oryza nivara38.958e-1168.9
LLPS-Orb-0365Oryza barthii38.958e-1168.9
LLPS-Orgl-2030Oryza glumaepatula38.958e-1168.9
LLPS-Orr-1884Oryza rufipogon38.958e-1168.9
LLPS-Ori-0408Oryza indica38.719e-2097.4
LLPS-Ors-2201Oryza sativa38.718e-2097.4
LLPS-Art-0160Arabidopsis thaliana38.717e-1994.4
LLPS-Org-0287Oryza glaberrima38.718e-2097.4
LLPS-Sem-0747Selaginella moellendorffii37.91e-2098.2
LLPS-Orp-0269Oryza punctata37.93e-1995.5
LLPS-Tru-0230Triticum urartu37.361e-0862.0
LLPS-Sei-0206Setaria italica35.482e-1584.0
LLPS-Sac-1026Saccharomyces cerevisiae34.539e-1375.5
LLPS-Orm-0483Oryza meridionalis33.872e-1377.4
LLPS-Trv-0258Trichoderma virens33.331e-0758.9
LLPS-Brr-0994Brassica rapa33.164e-1789.0
LLPS-Arl-0435Arabidopsis lyrata33.151e-1996.7
LLPS-Brn-2287Brassica napus32.652e-1996.3
LLPS-Bro-2042Brassica oleracea32.317e-1994.7
LLPS-Tum-1517Tuber melanosporum31.825e-0963.5
LLPS-Mao-0180Magnaporthe oryzae31.751e-0655.5
LLPS-Asg-0127Ashbya gossypii31.361e-1171.6
LLPS-Miv-0513Microbotryum violaceum31.331e-1687.4
LLPS-Asc-1378Aspergillus clavatus30.886e-0860.1
LLPS-Pug-1312Puccinia graminis30.411e-1997.1
LLPS-Met-1309Medicago truncatula30.089e-1375.1
LLPS-Put-0795Puccinia triticina30.031e-1894.0
LLPS-Cae-0499Caenorhabditis elegans29.622e-54 199
LLPS-Dac-1560Daucus carota29.263e-1892.8
LLPS-Yal-1030Yarrowia lipolytica29.179e-1375.1
LLPS-Vir-1012Vigna radiata28.574e-0757.4
LLPS-Osl-0613Ostreococcus lucimarinus28.575e-1994.7
LLPS-Chr-0940Chlamydomonas reinhardtii28.473e-0757.4
LLPS-Gas-0329Galdieria sulphuraria27.914e-2097.4
LLPS-Kop-1075Komagataella pastoris27.148e-1168.9
LLPS-Viv-0166Vitis vinifera27.02e-28 124
LLPS-Thc-0950Theobroma cacao26.241e-26 119
LLPS-Gor-0335Gossypium raimondii26.177e-29 125
LLPS-Php-0443Physcomitrella patens26.142e-29 127
LLPS-Spr-0499Sporisorium reilianum26.035e-1892.0
LLPS-Tra-2002Triticum aestivum25.644e-25 114
LLPS-Scs-0600Sclerotinia sclerotiorum25.438e-0859.7
LLPS-Hov-0819Hordeum vulgare25.41e-25 115
LLPS-Orbr-0682Oryza brachyantha25.372e-24 112
LLPS-Mae-2228Manihot esculenta25.361e-31 133
LLPS-Amt-0943Amborella trichopoda25.292e-30 130
LLPS-Prp-0398Prunus persica25.232e-27 120
LLPS-Mua-0339Musa acuminata25.193e-30 129
LLPS-Brd-0430Brachypodium distachyon25.04e-24 110
LLPS-Usm-1297Ustilago maydis24.859e-1581.6
LLPS-Beb-0888Beauveria bassiana24.493e-0654.7
LLPS-Glm-0442Glycine max24.431e-1997.1
LLPS-Hea-0179Helianthus annuus24.132e-24 111
LLPS-Cus-0005Cucumis sativus23.842e-1067.0
LLPS-Sob-0148Sorghum bicolor23.731e-20 100
LLPS-Sol-0418Solanum lycopersicum23.469e-2097.4
LLPS-Phv-0975Phaseolus vulgaris23.331e-1997.1
LLPS-Ved-0002Verticillium dahliae23.253e-1067.0
LLPS-Zem-1227Zea mays23.03e-1789.7
LLPS-Nec-0473Neurospora crassa22.933e-0964.3
LLPS-Pot-0622Populus trichocarpa22.578e-22 103