• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-1319
PRKAA1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Non-specific serine/threonine protein kinase
Gene Name: PRKAA1
Ensembl Gene: ENSECAG00000022617.2
Ensembl Protein: ENSECAP00000020185.2
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSECAT00000024304.2ENSECAP00000020185.2
UniProtF6V6T6, F6V6T6_HORSE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MQGEEGGTGA  PPSDPAPPRQ  GERLRPTARG  GDRAGGAGWR  LGGAVPLPRP  HPLPRRPPAP  60
61    GAALPAPSAP  SRGAMRRLSS  WRKMATAEKQ  KHDGRVKIGH  YILGDTLGVG  TFGKVKVGKH  120
121   ELTGHKVAVK  ILNRQKIRSL  DVVGKIRREI  QNLKLFRHPH  IIKLYQVIST  PSDIFMVMEY  180
181   VSGGELFDYI  CKNGRLDEKE  SRRLFQQILS  GVDYCHRHMV  VHRDLKPENV  LLDAHMNAKI  240
241   ADFGLSNMMS  DGEFLRTSCG  SPNYAAPEVI  SGRLYAGPEV  DIWSSGVILY  ALLCGTLPFD  300
301   DDHVPTLFKK  ICDGIFYTPQ  YLNPSVISLL  KHMLQVDPMK  RATIKDIREH  EWFKQDLPKY  360
361   LFPEDPSYSS  TMIDDEALKE  VCEKFECSEE  EVLSCLYNRN  HQDPLAVAYH  LIIDNRRIMN  420
421   EAKDFYLATS  PPDSFLDDHH  LTRPHPERVP  FLVAETPRAR  HTLDELNPQK  SKHQGVRKAK  480
481   WHLGIRSQSR  PNDIMAEVCR  AIKQLDYEWK  VVNPYYLRVR  RKNPVTSTYS  KMSLQLYQVD  540
541   SRTYLLDFRS  IDDEITEAKS  GTATPQRSGS  VSNYRSCQRS  DSDAEAQGKS  SEASLTSSVT  600
601   SLDSSPVDLT  PRPGSHTIEF  FEMCANLIKI  LAQ  633
Nucleotide CDS Sequence (FASTA)
1     ATGCAGGGCG  AGGAAGGGGG  TACCGGGGCC  CCTCCCAGCG  ACCCCGCCCC  GCCCCGCCAG  60
61    GGGGAGCGTC  TGCGCCCGAC  GGCCCGCGGC  GGGGACCGGG  CGGGCGGCGC  CGGGTGGCGT  120
121   CTCGGCGGCG  CGGTTCCCCT  CCCGCGTCCC  CACCCCCTCC  CTCGCCGGCC  GCCCGCCCCC  180
181   GGCGCGGCCC  TGCCCGCCCC  CTCCGCCCCC  TCCCGCGGCG  CCATGCGCAG  ACTCAGTTCC  240
241   TGGAGAAAGA  TGGCGACAGC  CGAGAAGCAG  AAACACGACG  GGCGGGTGAA  GATCGGCCAC  300
301   TACATCCTGG  GGGACACGCT  GGGGGTCGGC  ACGTTCGGCA  AAGTGAAGGT  TGGCAAACAT  360
361   GAATTGACTG  GGCATAAAGT  TGCTGTGAAG  ATACTCAATC  GCCAGAAGAT  TCGAAGCCTC  420
421   GATGTGGTTG  GAAAAATCCG  CAGAGAAATT  CAGAACCTCA  AGCTTTTCAG  GCATCCTCAT  480
481   ATAATTAAAC  TGTACCAGGT  CATCAGTACA  CCATCTGATA  TTTTCATGGT  GATGGAATAT  540
541   GTCTCAGGAG  GAGAGCTATT  TGATTATATC  TGTAAAAATG  GAAGGCTCGA  TGAAAAAGAA  600
601   AGTCGACGTC  TGTTCCAACA  GATCCTTTCT  GGTGTGGATT  ATTGTCACAG  GCATATGGTG  660
661   GTCCATAGAG  ACTTGAAACC  TGAAAACGTC  CTGCTTGATG  CACACATGAA  TGCAAAGATA  720
721   GCTGATTTTG  GTCTTTCAAA  CATGATGTCA  GATGGTGAAT  TTTTAAGAAC  GAGTTGTGGC  780
781   TCACCCAACT  ATGCTGCCCC  AGAGGTCATT  TCAGGAAGAT  TGTATGCAGG  CCCAGAGGTA  840
841   GACATATGGA  GCAGCGGGGT  TATTCTCTAT  GCTTTATTAT  GTGGAACCCT  TCCATTTGAT  900
901   GATGATCATG  TGCCAACTCT  TTTTAAGAAG  ATATGTGATG  GGATCTTTTA  TACCCCTCAG  960
961   TATTTAAATC  CATCCGTGAT  TAGCCTTTTG  AAACATATGC  TGCAGGTGGA  TCCCATGAAG  1020
1021  CGGGCCACAA  TCAAAGATAT  CAGGGAACAT  GAATGGTTTA  AACAAGACCT  TCCAAAATAT  1080
1081  CTCTTTCCTG  AGGACCCATC  ATATAGTTCA  ACTATGATTG  ATGATGAAGC  CTTAAAAGAA  1140
1141  GTATGTGAAA  AATTTGAATG  CTCAGAAGAG  GAGGTTCTCA  GCTGCCTTTA  TAACCGAAAT  1200
1201  CACCAGGACC  CTTTGGCAGT  GGCCTACCAC  CTCATCATAG  ATAACAGGAG  AATAATGAAT  1260
1261  GAAGCCAAAG  ATTTTTACTT  GGCGACAAGC  CCACCTGATT  CTTTTCTTGA  TGATCACCAT  1320
1321  TTGACTCGGC  CCCATCCTGA  AAGAGTACCA  TTCTTGGTTG  CTGAAACACC  AAGGGCACGC  1380
1381  CATACTCTCG  ATGAATTAAA  TCCACAGAAA  TCCAAACACC  AAGGTGTAAG  AAAAGCCAAA  1440
1441  TGGCATTTGG  GAATTAGAAG  TCAAAGTCGA  CCAAATGATA  TCATGGCAGA  AGTTTGTAGA  1500
1501  GCAATTAAAC  AACTGGATTA  TGAATGGAAG  GTTGTAAACC  CATATTACTT  GCGTGTTCGA  1560
1561  AGGAAGAATC  CTGTGACAAG  TACCTACTCC  AAAATGAGTC  TACAGTTATA  CCAAGTGGAC  1620
1621  AGTAGAACAT  ACTTACTGGA  TTTCCGTAGT  ATTGATGATG  AAATTACTGA  AGCCAAATCC  1680
1681  GGGACTGCTA  CTCCACAAAG  ATCGGGATCC  GTTAGCAACT  ATCGATCTTG  TCAGAGGAGT  1740
1741  GATTCGGATG  CTGAGGCTCA  AGGAAAATCC  TCAGAAGCTT  CTCTTACCTC  ATCGGTGACC  1800
1801  TCACTTGACT  CTTCTCCTGT  TGACTTAACT  CCAAGACCTG  GAAGTCACAC  AATAGAGTTT  1860
1861  TTTGAGATGT  GTGCGAATCT  AATTAAAATT  CTTGCACAGT  AA  1902

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Poa-0829Pongo abelii99.820.01060
LLPS-Caf-0661Canis familiaris99.810.0 997
LLPS-Otg-0541Otolemur garnettii99.640.01059
LLPS-Mal-1551Mandrillus leucophaeus99.640.01059
LLPS-Sus-0549Sus scrofa99.640.01058
LLPS-Mup-2691Mustela putorius furo99.610.0 995
LLPS-Urm-2206Ursus maritimus99.60.0 965
LLPS-Bot-3624Bos taurus99.460.01059
LLPS-Ict-2631Ictidomys tridecemlineatus99.220.0 994
LLPS-Loa-1634Loxodonta africana99.110.01055
LLPS-Dio-2336Dipodomys ordii99.030.0 991
LLPS-Fud-0507Fukomys damarensis99.030.0 991
LLPS-Ran-1325Rattus norvegicus98.930.01055
LLPS-Myl-3350Myotis lucifugus98.640.0 985
LLPS-Mum-0542Mus musculus98.570.01052
LLPS-Cap-0962Cavia porcellus98.030.01040
LLPS-Chs-1597Chlorocebus sabaeus97.510.0 915
LLPS-Mod-2252Monodelphis domestica97.320.01047
LLPS-Nol-0017Nomascus leucogenys97.210.01051
LLPS-Hos-1982Homo sapiens97.210.01052
LLPS-Pat-1224Pan troglodytes97.210.01052
LLPS-Pap-0318Pan paniscus97.210.01052
LLPS-Aon-0958Aotus nancymaae97.210.01051
LLPS-Sah-2103Sarcophilus harrisii97.140.01045
LLPS-Mam-3830Macaca mulatta97.040.01050
LLPS-Rhb-1383Rhinopithecus bieti97.040.01050
LLPS-Man-0262Macaca nemestrina97.040.01050
LLPS-Paa-3057Papio anubis97.040.01050
LLPS-Gog-2182Gorilla gorilla97.040.01050
LLPS-Cea-0925Cercocebus atys97.040.01050
LLPS-Maf-0470Macaca fascicularis97.040.01050
LLPS-Aim-1775Ailuropoda melanoleuca96.860.01046
LLPS-Ova-2169Ovis aries96.860.01050
LLPS-Orc-2025Oryctolagus cuniculus96.450.01026
LLPS-Tut-1256Tursiops truncatus95.820.01044
LLPS-Fec-3621Felis catus94.60.01045
LLPS-Gaga-1516Gallus gallus94.120.01009
LLPS-Fia-1319Ficedula albicollis93.770.01005
LLPS-Pes-2748Pelodiscus sinensis93.580.01004
LLPS-Meg-0474Meleagris gallopavo93.560.0 856
LLPS-Caj-1090Callithrix jacchus93.360.01073
LLPS-Anp-1333Anas platyrhynchos93.310.0 952
LLPS-Tag-2723Taeniopygia guttata93.240.0 998
LLPS-Anc-3459Anolis carolinensis92.930.0 978
LLPS-Mea-0597Mesocricetus auratus91.950.0 956
LLPS-Leo-2665Lepisosteus oculatus90.180.0 902
LLPS-Lac-0992Latimeria chalumnae90.020.0 947
LLPS-Xet-1008Xenopus tropicalis89.130.0 952
LLPS-Ora-0803Ornithorhynchus anatinus88.350.0 964
LLPS-Scf-0077Scleropages formosus85.540.0 928
LLPS-Tar-1430Takifugu rubripes84.470.0 921
LLPS-Orl-0169Oryzias latipes83.830.0 927
LLPS-Ten-1905Tetraodon nigroviridis83.650.0 926
LLPS-Orn-0091Oreochromis niloticus83.60.0 912
LLPS-Icp-0177Ictalurus punctatus83.510.0 912
LLPS-Dar-2834Danio rerio83.450.0 916
LLPS-Gaa-1073Gasterosteus aculeatus83.30.0 922
LLPS-Pof-2600Poecilia formosa83.010.0 909
LLPS-Scm-1640Scophthalmus maximus82.930.0 915
LLPS-Xim-0658Xiphophorus maculatus82.830.0 907
LLPS-Asm-3304Astyanax mexicanus82.580.0 911
LLPS-Cas-1367Carlito syrichta74.230.0 759
LLPS-Via-0585Vigna angularis68.447e-118 361
LLPS-Spr-1292Sporisorium reilianum66.544e-119 381
LLPS-Usm-1351Ustilago maydis66.186e-118 378
LLPS-Dos-1280Dothistroma septosporum62.313e-108 353
LLPS-Miv-1288Microbotryum violaceum62.172e-102 335
LLPS-Asni-0301Aspergillus niger61.186e-105 343
LLPS-Asc-0236Aspergillus clavatus61.181e-103 339
LLPS-Cogr-0633Colletotrichum graminicola61.157e-110 353
LLPS-Coo-1397Colletotrichum orbiculare61.152e-110 355
LLPS-Asfu-1361Aspergillus fumigatus60.782e-103 338
LLPS-Nef-0075Neosartorya fischeri60.789e-104 339
LLPS-Ast-0387Aspergillus terreus60.781e-103 339
LLPS-Pytr-1405Pyrenophora triticirepentis60.56e-109 355
LLPS-Asf-1515Aspergillus flavus60.399e-104 339
LLPS-Aso-1468Aspergillus oryzae60.391e-103 339
LLPS-Pyt-1611Pyrenophora teres60.147e-108 352
LLPS-Trr-1185Trichoderma reesei60.073e-109 350
LLPS-Nec-0056Neurospora crassa60.074e-109 352
LLPS-Cii-0028Ciona intestinalis59.890.0 613
LLPS-Zyt-0896Zymoseptoria tritici59.52e-109 354
LLPS-Crn-0778Cryptococcus neoformans59.484e-107 347
LLPS-Mel-1245Melampsora laricipopulina59.471e-97 317
LLPS-Beb-0941Beauveria bassiana59.448e-110 353
LLPS-Fus-1526Fusarium solani59.353e-102 332
LLPS-Map-1369Magnaporthe poae59.297e-106 343
LLPS-Gag-1166Gaeumannomyces graminis59.296e-106 343
LLPS-Lem-0657Leptosphaeria maculans58.94e-110 358
LLPS-Mao-0805Magnaporthe oryzae58.565e-106 345
LLPS-Cis-0246Ciona savignyi58.320.0 609
LLPS-Blg-0735Blumeria graminis58.273e-103 337
LLPS-Phn-1502Phaeosphaeria nodorum58.083e-113 352
LLPS-Cae-0535Caenorhabditis elegans58.070.0 572
LLPS-Trv-1287Trichoderma virens57.498e-107 345
LLPS-Pug-1511Puccinia graminis57.493e-98 322
LLPS-Scs-0667Sclerotinia sclerotiorum57.341e-105 342
LLPS-Drm-1272Drosophila melanogaster56.380.0 584
LLPS-Phv-2490Phaseolus vulgaris55.437e-93 295
LLPS-Zem-1597Zea mays54.489e-126 395
LLPS-Ved-0725Verticillium dahliae53.961e-85 289
LLPS-Pot-2455Populus trichocarpa53.776e-136 415
LLPS-Mae-2498Manihot esculenta53.13e-135 413
LLPS-Dac-0262Daucus carota52.252e-132 405
LLPS-Tru-0510Triticum urartu52.193e-128 395
LLPS-Amt-0701Amborella trichopoda52.127e-84 274
LLPS-Brn-1105Brassica napus52.011e-133 409
LLPS-Lep-2156Leersia perrieri52.03e-135 412
LLPS-Tra-0651Triticum aestivum51.851e-128 396
LLPS-Vir-1659Vigna radiata51.82e-132 408
LLPS-Bro-2943Brassica oleracea51.774e-133 407
LLPS-Hov-2168Hordeum vulgare51.741e-127 393
LLPS-Mua-2122Musa acuminata51.715e-117 364
LLPS-Ors-0910Oryza sativa51.613e-130 400
LLPS-Ori-0450Oryza indica51.613e-130 400
LLPS-Brd-0942Brachypodium distachyon51.513e-128 395
LLPS-Glm-1082Glycine max51.292e-130 400
LLPS-Php-1689Physcomitrella patens51.262e-133 410
LLPS-Brr-2913Brassica rapa49.772e-128 395
LLPS-Sob-2336Sorghum bicolor49.432e-126 390
LLPS-Sem-0351Selaginella moellendorffii49.431e-130 400
LLPS-Gor-2540Gossypium raimondii49.25e-86 280
LLPS-Sei-1393Setaria italica49.22e-127 392
LLPS-Gas-1092Galdieria sulphuraria49.134e-126 389
LLPS-Abg-1853Absidia glauca48.842e-92 320
LLPS-Hea-0165Helianthus annuus48.559e-135 411
LLPS-Orr-1376Oryza rufipogon48.033e-136 415
LLPS-Orgl-0300Oryza glumaepatula48.036e-135 416
LLPS-Orni-0188Oryza nivara48.036e-135 416
LLPS-Orb-2279Oryza barthii48.037e-136 416
LLPS-Orm-0713Oryza meridionalis47.838e-136 414
LLPS-Orbr-0158Oryza brachyantha47.753e-136 415
LLPS-Met-1164Medicago truncatula47.633e-131 402
LLPS-Orp-0257Oryza punctata47.344e-111 350
LLPS-Chc-1066Chondrus crispus47.052e-125 387
LLPS-Nia-2028Nicotiana attenuata46.789e-128 393
LLPS-Art-2601Arabidopsis thaliana46.532e-128 395
LLPS-Arl-1065Arabidopsis lyrata46.532e-128 395
LLPS-Sol-1999Solanum lycopersicum45.763e-124 384
LLPS-Cym-1130Cyanidioschyzon merolae45.193e-115 362
LLPS-Viv-1220Vitis vinifera44.959e-112 353
LLPS-Coc-1456Corchorus capsularis43.419e-118 367
LLPS-Kop-0972Komagataella pastoris43.394e-128 395
LLPS-Yal-0727Yarrowia lipolytica43.14e-123 384
LLPS-Asg-1203Ashbya gossypii41.767e-120 376
LLPS-Scj-1045Schizosaccharomyces japonicus41.24e-115 363
LLPS-Sac-0308Saccharomyces cerevisiae40.868e-118 372
LLPS-Scp-1189Schizosaccharomyces pombe40.284e-111 352
LLPS-Scc-0225Schizosaccharomyces cryophilus40.083e-107 342