LLPS-Eqc-1308
SYK
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Tyrosine-protein kinase |
| Gene Name: | SYK |
| Ensembl Gene: | ENSECAG00000009488.2 |
| Ensembl Protein: | ENSECAP00000028698.1 |
| Organism: | Equus caballus |
| Taxa ID: | 9796 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle, Centrosome/Spindle pole body, Stress granule, Receptor cluster | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSECAT00000049895.1 | ENSECAP00000028698.1 |
| Ensembl | ENSECAT00000059308.1 | ENSECAP00000036880.1 |
| Ensembl | ENSECAT00000052938.1 | ENSECAP00000040317.1 |
| Ensembl | ENSECAT00000010223.2 | ENSECAP00000007870.2 |
| Ensembl | ENSECAT00000058772.1 | ENSECAP00000029800.1 |
| UniProt | F7BR88, F7BR88_HORSE | |
| RefSeq | XM_001494629.2 | XP_001494679.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAGGTADGAN NLPFFFGNIT REEAEDYLVQ GGMSDGLYLL RQSRNYLGGF ALSVAHGRKA 60 61 HHYTIERELN GTYAIAGGRT HSSPAELCHY HSQESDGLVC LLTKPFNRPP GVQPKTGPFE 120 121 DLKENLIREY VKQTWNLQGE ALEQAIISQK PQLEKLIATT AHEKMPWFHG KISRDESEQV 180 181 VLIGSKINGK FLIRARDNNG SYALCLLHEG KVLHYRIDKD KTGKLSIPDG KKFDTLWQLV 240 241 EHYSYKADGL LRVLTVPCQK IGGQTGNINF GGRPQLPSSH PATWSAGGII SRIKSYSFPK 300 301 PGHRKSSSSQ GNHPESSATS NPYELDRGTS ATERDAQREA MPMDTEVYES PYADPEEIRP 360 361 KEVYLDRNLL TLEDNELGSG NFGTVKKGYY QMKKVVKTVA VKILKNEAND PALKDELLAE 420 421 ANVMQQLDNP YIVRMIGICE AESWMLVMEM AELGPLNKYL QQNRHVKDKN IIELVHQVSM 480 481 GMKYLEESNF VHRDLAARNV LLVTQHYAKI SDFGLSKALR ADESYYKAQT HGKWPVKWYA 540 541 PECINYYKFS SKSDVWSFGV LMWEAFSYGQ KPYRGMKGSE VSAMLEKGER MGCPAGCPRE 600 601 MYELMKLCWT YDSPALGHIP VECQATHSRA AFQPSHGSWP VPVWGLGTGR GIYSPHRGSR 660 661 LTTRFCSRRE RGETAPRMGR RNVLEEEGWT FKAEGGASAN SASQASPVLP LDQALL 716 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTGGAG GCACGGCCGA CGGCGCCAAC AACCTGCCCT TCTTCTTTGG CAACATCACC 60 61 CGGGAGGAGG CAGAAGACTA CCTGGTCCAG GGGGGCATGA GCGATGGGCT CTACCTGCTG 120 121 CGCCAGAGCC GCAATTACCT GGGTGGCTTC GCCCTGTCGG TGGCGCACGG GAGGAAGGCG 180 181 CACCACTACA CCATCGAGCG GGAGCTGAAT GGGACGTACG CCATTGCGGG CGGCAGGACG 240 241 CACAGCAGCC CCGCCGAGCT CTGCCACTAC CACTCCCAGG AGTCGGATGG CCTCGTCTGC 300 301 CTCCTCACGA AGCCCTTCAA CCGGCCGCCC GGGGTGCAGC CCAAGACGGG ACCCTTTGAG 360 361 GACCTGAAGG AGAACCTCAT TAGGGAATAC GTGAAACAGA CATGGAACCT GCAGGGTGAA 420 421 GCTCTGGAGC AGGCCATTAT CAGCCAGAAA CCTCAGCTGG AGAAGCTGAT CGCCACCACG 480 481 GCCCACGAAA AGATGCCCTG GTTCCATGGA AAAATCTCTC GGGATGAATC TGAGCAAGTC 540 541 GTCCTGATAG GATCCAAGAT AAATGGGAAA TTTCTGATCA GGGCCAGGGA CAACAACGGG 600 601 TCTTACGCCC TGTGCCTGCT GCACGAGGGG AAAGTGCTGC ACTACCGAAT CGATAAGGAC 660 661 AAAACGGGGA AGCTGTCCAT CCCGGACGGA AAGAAGTTCG ACACGCTCTG GCAGCTCGTA 720 721 GAGCATTATT CCTATAAAGC AGATGGTTTG TTAAGAGTTC TTACAGTTCC ATGTCAAAAA 780 781 ATTGGCGGAC AGACAGGAAA TATTAATTTT GGAGGTCGTC CACAACTCCC CAGTTCCCAT 840 841 CCTGCGACTT GGTCAGCGGG TGGAATAATC TCAAGAATCA AATCATACTC CTTCCCAAAG 900 901 CCTGGCCACA GAAAGAGCTC CTCTTCCCAA GGGAACCACC CCGAGAGTTC TGCGACGTCC 960 961 AACCCTTATG AGCTAGACCG AGGGACCTCG GCCACCGAAA GAGATGCCCA GAGAGAAGCC 1020 1021 ATGCCCATGG ACACCGAAGT GTACGAAAGC CCCTATGCGG ACCCGGAGGA GATCAGGCCC 1080 1081 AAGGAGGTCT ACCTGGATCG AAACCTGCTG ACCCTGGAGG ACAACGAGCT GGGCTCTGGT 1140 1141 AACTTTGGGA CCGTGAAGAA GGGTTACTAC CAGATGAAAA AGGTCGTGAA AACAGTGGCT 1200 1201 GTGAAAATCC TGAAAAATGA GGCCAATGAC CCTGCTCTTA AAGATGAGTT ATTAGCAGAA 1260 1261 GCCAATGTCA TGCAGCAACT CGACAATCCT TACATCGTGC GTATGATCGG GATCTGTGAA 1320 1321 GCCGAGTCCT GGATGCTGGT CATGGAGATG GCGGAACTGG GTCCACTCAA TAAATATTTA 1380 1381 CAGCAGAACA GGCATGTCAA GGATAAGAAC ATCATCGAGC TGGTTCATCA GGTTTCTATG 1440 1441 GGAATGAAAT ATTTGGAGGA GTCCAATTTT GTGCACAGAG ATCTGGCTGC AAGAAATGTA 1500 1501 TTGCTGGTTA CTCAACATTA TGCCAAGATC AGTGATTTTG GACTTTCCAA AGCACTTCGT 1560 1561 GCTGATGAAA GCTACTACAA GGCCCAGACC CACGGGAAGT GGCCCGTGAA GTGGTATGCT 1620 1621 CCAGAATGCA TCAACTACTA CAAGTTCTCC AGCAAGAGTG ACGTCTGGAG CTTCGGCGTG 1680 1681 TTGATGTGGG AAGCCTTTTC CTATGGGCAG AAGCCGTACC GGGGAATGAA AGGGAGTGAA 1740 1741 GTTTCCGCAA TGCTGGAGAA AGGAGAGAGG ATGGGCTGCC CCGCGGGGTG TCCCAGAGAG 1800 1801 ATGTATGAGC TGATGAAGCT GTGCTGGACC TATGACTCGC CTGCACTTGG GCACATCCCT 1860 1861 GTGGAGTGTC AAGCGACCCA CTCAAGAGCC GCATTCCAGC CCTCTCATGG CAGCTGGCCT 1920 1921 GTCCCTGTGT GGGGACTCGG CACGGGACGT GGTATTTATA GTCCGCATCG CGGGTCCCGC 1980 1981 CTCACCACGC GTTTCTGCAG CAGGAGAGAG CGAGCCACAT GGATCCCGAC CGTGAATGAA 2040 2041 TAA 2043 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Fec-3710 | Felis catus | 93.47 | 0.0 | 1174 |
| LLPS-Sus-2046 | Sus scrofa | 93.41 | 0.0 | 1154 |
| LLPS-Caf-2887 | Canis familiaris | 93.3 | 0.0 | 1170 |
| LLPS-Aim-4158 | Ailuropoda melanoleuca | 93.25 | 0.0 | 1159 |
| LLPS-Myl-4135 | Myotis lucifugus | 92.96 | 0.0 | 1153 |
| LLPS-Bot-0741 | Bos taurus | 92.92 | 0.0 | 1150 |
| LLPS-Paa-1147 | Papio anubis | 92.8 | 0.0 | 1165 |
| LLPS-Gog-1200 | Gorilla gorilla | 92.8 | 0.0 | 1164 |
| LLPS-Chs-0331 | Chlorocebus sabaeus | 92.8 | 0.0 | 1165 |
| LLPS-Maf-1400 | Macaca fascicularis | 92.8 | 0.0 | 1165 |
| LLPS-Pap-3790 | Pan paniscus | 92.8 | 0.0 | 1165 |
| LLPS-Pat-3578 | Pan troglodytes | 92.8 | 0.0 | 1165 |
| LLPS-Hos-1656 | Homo sapiens | 92.8 | 0.0 | 1165 |
| LLPS-Ova-3804 | Ovis aries | 92.45 | 0.0 | 1149 |
| LLPS-Aon-3002 | Aotus nancymaae | 92.31 | 0.0 | 1161 |
| LLPS-Otg-2617 | Otolemur garnettii | 92.16 | 0.0 | 1155 |
| LLPS-Cas-2366 | Carlito syrichta | 91.83 | 0.0 | 1158 |
| LLPS-Loa-3521 | Loxodonta africana | 91.67 | 0.0 | 1133 |
| LLPS-Caj-4018 | Callithrix jacchus | 91.65 | 0.0 | 1155 |
| LLPS-Orc-0904 | Oryctolagus cuniculus | 91.5 | 0.0 | 1136 |
| LLPS-Dio-1231 | Dipodomys ordii | 90.0 | 0.0 | 1118 |
| LLPS-Nol-0340 | Nomascus leucogenys | 89.64 | 0.0 | 944 |
| LLPS-Mam-1408 | Macaca mulatta | 89.27 | 0.0 | 1164 |
| LLPS-Mum-2825 | Mus musculus | 89.05 | 0.0 | 1120 |
| LLPS-Ict-0997 | Ictidomys tridecemlineatus | 88.89 | 0.0 | 1104 |
| LLPS-Ran-2861 | Rattus norvegicus | 88.56 | 0.0 | 1096 |
| LLPS-Mea-1764 | Mesocricetus auratus | 88.56 | 0.0 | 1114 |
| LLPS-Fud-3815 | Fukomys damarensis | 88.42 | 0.0 | 1122 |
| LLPS-Man-0888 | Macaca nemestrina | 88.38 | 0.0 | 1085 |
| LLPS-Cea-1406 | Cercocebus atys | 87.77 | 0.0 | 1087 |
| LLPS-Mal-3612 | Mandrillus leucophaeus | 86.42 | 0.0 | 1056 |
| LLPS-Poa-3147 | Pongo abelii | 85.27 | 0.0 | 1048 |
| LLPS-Sah-2276 | Sarcophilus harrisii | 85.19 | 0.0 | 811 |
| LLPS-Urm-1011 | Ursus maritimus | 84.83 | 0.0 | 1021 |
| LLPS-Mod-2373 | Monodelphis domestica | 81.09 | 0.0 | 1003 |
| LLPS-Cap-0679 | Cavia porcellus | 81.08 | 0.0 | 992 |
| LLPS-Pes-1025 | Pelodiscus sinensis | 79.2 | 0.0 | 700 |
| LLPS-Gaga-1665 | Gallus gallus | 77.42 | 0.0 | 1019 |
| LLPS-Fia-1563 | Ficedula albicollis | 77.42 | 0.0 | 1005 |
| LLPS-Anp-1616 | Anas platyrhynchos | 77.27 | 0.0 | 1020 |
| LLPS-Tag-0823 | Taeniopygia guttata | 77.16 | 0.0 | 985 |
| LLPS-Lac-2552 | Latimeria chalumnae | 74.59 | 0.0 | 948 |
| LLPS-Anc-1081 | Anolis carolinensis | 74.44 | 0.0 | 931 |
| LLPS-Scf-0877 | Scleropages formosus | 71.12 | 0.0 | 898 |
| LLPS-Leo-1935 | Lepisosteus oculatus | 70.87 | 0.0 | 897 |
| LLPS-Orn-0385 | Oreochromis niloticus | 70.2 | 0.0 | 871 |
| LLPS-Orl-1584 | Oryzias latipes | 69.89 | 0.0 | 870 |
| LLPS-Xim-0351 | Xiphophorus maculatus | 69.21 | 0.0 | 861 |
| LLPS-Icp-1610 | Ictalurus punctatus | 69.06 | 0.0 | 853 |
| LLPS-Asm-0585 | Astyanax mexicanus | 68.87 | 0.0 | 848 |
| LLPS-Dar-1032 | Danio rerio | 68.79 | 0.0 | 867 |
| LLPS-Meg-1571 | Meleagris gallopavo | 68.46 | 0.0 | 874 |
| LLPS-Xet-1876 | Xenopus tropicalis | 68.36 | 0.0 | 849 |
| LLPS-Scm-3053 | Scophthalmus maximus | 68.35 | 0.0 | 855 |
| LLPS-Gaa-1109 | Gasterosteus aculeatus | 66.83 | 0.0 | 828 |
| LLPS-Ten-1747 | Tetraodon nigroviridis | 65.49 | 0.0 | 814 |
| LLPS-Tar-0064 | Takifugu rubripes | 65.41 | 0.0 | 813 |
| LLPS-Ora-3295 | Ornithorhynchus anatinus | 43.75 | 7e-53 | 202 |
| LLPS-Pof-3518 | Poecilia formosa | 43.7 | 3e-56 | 213 |
| LLPS-Rhb-1350 | Rhinopithecus bieti | 43.33 | 1e-52 | 202 |
| LLPS-Cii-1016 | Ciona intestinalis | 43.09 | 1e-54 | 205 |
| LLPS-Mup-3931 | Mustela putorius furo | 41.76 | 1e-52 | 202 |