LLPS-Eqc-0816
CRAMP1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Cramped chromatin regulator homolog 1 |
| Gene Name: | CRAMP1 |
| Ensembl Gene: | ENSECAG00000023299.2 |
| Ensembl Protein: | ENSECAP00000020840.2 |
| Organism: | Equus caballus |
| Taxa ID: | 9796 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| PcG body, P-body, Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSECAT00000025061.2 | ENSECAP00000020840.2 |
| UniProt | F6W2R8, F6W2R8_HORSE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTVKLGDGGS GEEGLKRLGK RSADEDALEG EGAGGGDAAE ESGGTKRDGK TPRDGGDGPP 60 61 APSGGPQAPS PPPACPQDQH HFLRSSVRPQ SKRLRKDSSC AGGSSSAGSS GPRGKGADGG 120 121 GSSSGNGSGV APAAPAGGSR SSSRNLGSSG AEKEEGKKVR RQWESWSTED KNTFFEGLYE 180 181 HGKDFEAIQN NIALKYKKKG KPASMVKNKE QVRHFYYRTW HKITKYIDFD NVFSRGLKKS 240 241 SQELYGLICY GELRKKIGGC MDDKNATKLN ELIQVGATTV RYKGRNLRIK APMCRALKKL 300 301 CDPDGLSDEE DQKPVRLPLK VPVELQPRNN HAWARVQRLA QNPRLRMIVE LHRKVSSLIE 360 361 FLKQKWALHE VRIRKTLEER QLQDSFTEPL QEKVALHLFP GENCTLTPLP GVARVVHSKA 420 421 FCTVHWQEGG RCKQSAKDAH TLPPAQILGI QSGQGTARGQ VKCPRGGAEG RVGGRPPPST 480 481 DALQSSGESS PESAPGEGAV PSLSSPEAPD RLPSGAQDTG GRLEKTPVVT PAEGGDGPAQ 540 541 EPGAVTCACS QLPELEDELS LLDPFPRYMK SCQDLIIPEQ CRCADSRPSG RASPETRVPS 600 601 SADTGDLARA RAPSPIRAPP GPEPQPSPGL QPDVCTKDSA DAPVEEPQEQ VSSSDPPPPQ 660 661 GQPAARPLKD VPASRLAQQL REEGWNLQTS ESLTLAEVYL MMGKPNKLQL EYDWLAVLGP 720 721 EGQAPGGQAQ GPRTGSPPTT LHKQRLLSCL LKLISTEVNP RLAPEASAGS TASVRPTQEE 780 781 QSTTPPGKVV TISSRSPRCP RNQSALRNGK TFSPNSAACS SGLRNPPRPL LVAGPSSTGS 840 841 SDSDGGLFAV PTTLPPNSRH GKLFSPSKET ELTFRQHLNS ISMQSDFFLP KPRKLRNRHL 900 901 RKPLVVQRTL LPRPSENQSH NVCSFSILSN SSVTGRGSFR PIQSSLTKAA LSRPIVPKVL 960 961 PPQATGHLAS AIDLAAQSAG IIPGSPLPVL DAEGLPGISP LSADEVTAAA SGRDSTGTHP 1020 1021 NGDPLPAVRG TSDPFISVAS RPEQEPVTDG FQGSPVLSLS ELSKPPLHNG LSTPLPSSEG 1080 1081 SSTRLSPPNV SALLDISLPG PPEDVLSQGE PATQISDSII EIAISSGQYG EGVPLSPAKL 1140 1141 NGSDSSKSLP SPSSSPQPDW IASPTHDPQW CPSDPTDSSL SSLFASFISP EKSRKMLPTP 1200 1201 IGTNSGTSLL GPSLLDGNSR DSFVSRSLAD VAEVVDSQLV CMMNENSIDY ISRFNDLAQE 1260 1261 LSIAEPSRRE VLFDGGGSGP PVGDLSQ 1287 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACAGTGA AGTTGGGAGA CGGCGGCAGC GGGGAGGAAG GGCTCAAGAG GCTGGGCAAG 60 61 AGGTCGGCCG ATGAGGACGC GCTGGAAGGA GAGGGCGCCG GCGGCGGGGA CGCGGCCGAG 120 121 GAGAGCGGCG GCACAAAGAG GGACGGCAAG ACCCCCCGGG ACGGCGGCGA CGGGCCCCCG 180 181 GCCCCCTCGG GCGGCCCGCA GGCCCCGTCC CCGCCGCCCG CCTGCCCCCA GGACCAGCAC 240 241 CACTTCCTCA GGTCCAGCGT GAGGCCGCAG AGCAAGAGGC TCAGGAAGGA CTCGTCCTGC 300 301 GCCGGGGGGA GCAGCAGCGC CGGCAGCTCG GGGCCCCGCG GCAAAGGAGC CGACGGGGGT 360 361 GGATCGTCGT CCGGAAATGG CTCTGGAGTT GCCCCCGCCG CCCCTGCAGG GGGCTCTCGC 420 421 TCCTCCTCCC GGAACTTAGG GTCTTCAGGC GCTGAGAAGG AAGAGGGCAA GAAGGTGCGG 480 481 CGGCAGTGGG AGTCGTGGAG CACCGAGGAC AAGAATACTT TCTTCGAGGG GCTGTACGAG 540 541 CACGGGAAAG ACTTCGAAGC GATTCAGAAC AACATTGCTC TGAAGTACAA GAAGAAAGGC 600 601 AAGCCTGCGA GCATGGTGAA GAACAAGGAG CAGGTCCGCC ACTTCTACTA CCGCACGTGG 660 661 CACAAGATCA CCAAGTACAT TGACTTTGAC AACGTGTTCT CTCGCGGGCT GAAGAAGTCA 720 721 TCCCAGGAGC TGTATGGCCT GATCTGCTAC GGCGAGCTGC GGAAGAAGAT CGGGGGCTGT 780 781 ATGGATGACA AGAACGCGAC CAAGTTGAAC GAGCTCATTC AGGTGGGGGC CACCACGGTA 840 841 CGCTACAAAG GGAGAAACCT GCGGATCAAA GCCCCCATGT GCCGAGCCCT GAAGAAGCTC 900 901 TGTGACCCAG ATGGCTTGAG TGACGAAGAG GACCAGAAAC CAGTGCGCCT GCCCCTGAAA 960 961 GTCCCAGTAG AGCTGCAGCC GCGGAACAAC CATGCCTGGG CCCGAGTGCA GAGGCTGGCC 1020 1021 CAGAACCCGA GGCTCAGGAT GATCGTGGAG CTCCATCGAA AGGTCTCCAG CCTCATCGAG 1080 1081 TTCTTGAAGC AGAAGTGGGC ACTCCATGAA GTGCGAATTA GGAAGACACT TGAGGAGCGG 1140 1141 CAGCTACAGG ACTCGTTCAC AGAGCCGTTG CAGGAGAAGG TGGCGCTGCA CCTCTTCCCG 1200 1201 GGAGAGAACT GCACGCTGAC GCCGCTGCCT GGAGTGGCCC GCGTGGTGCA CTCCAAGGCC 1260 1261 TTCTGCACGG TGCACTGGCA GGAGGGCGGC CGGTGCAAGC AGAGTGCCAA GGATGCCCAC 1320 1321 ACGCTGCCTC CAGCCCAGAT CCTGGGCATC CAGAGCGGGC AGGGCACAGC CAGAGGCCAG 1380 1381 GTCAAGTGCC CACGGGGTGG CGCTGAGGGC AGGGTGGGGG GACGGCCCCC TCCCTCCACC 1440 1441 GATGCTTTGC AGAGCTCTGG AGAGAGTTCT CCTGAAAGTG CCCCTGGGGA GGGTGCTGTT 1500 1501 CCGAGCCTCA GCAGCCCAGA GGCTCCTGAC AGGCTTCCCT CTGGGGCCCA GGACACTGGG 1560 1561 GGACGGCTTG AGAAGACCCC TGTGGTCACT CCTGCAGAGG GAGGGGATGG CCCTGCCCAA 1620 1621 GAGCCCGGGG CTGTGACATG TGCCTGCAGC CAGCTCCCAG AGCTGGAGGA TGAGCTATCC 1680 1681 CTCCTGGACC CCTTCCCCCG CTACATGAAG TCCTGTCAGG ACCTCATCAT CCCCGAGCAG 1740 1741 TGCCGCTGTG CGGACTCACG GCCCTCGGGA CGCGCCTCCC CAGAGACTCG TGTCCCCAGC 1800 1801 AGTGCGGATA CGGGCGACCT CGCCCGGGCC AGGGCACCGT CCCCCATCCG CGCCCCGCCT 1860 1861 GGCCCAGAGC CTCAGCCCAG CCCCGGGCTC CAGCCGGATG TTTGCACTAA AGACTCGGCA 1920 1921 GATGCACCTG TAGAGGAGCC CCAGGAGCAG GTGAGCTCCT CGGACCCTCC GCCACCTCAG 1980 1981 GGACAGCCTG CTGCCAGGCC TCTGAAGGAT GTCCCTGCCA GCCGGCTGGC CCAGCAGCTC 2040 2041 CGTGAGGAGG GCTGGAACCT ACAGACCTCC GAAAGCCTCA CGCTGGCCGA AGTCTACCTC 2100 2101 ATGATGGGCA AGCCGAACAA GCTGCAGTTG GAATATGACT GGCTGGCTGT GCTGGGCCCA 2160 2161 GAGGGCCAGG CCCCTGGCGG GCAGGCCCAG GGCCCCCGCA CCGGCTCCCC ACCCACCACC 2220 2221 CTCCACAAGC AGCGCCTCCT CAGCTGCCTC CTAAAGCTCA TCTCTACCGA AGTCAACCCC 2280 2281 AGGCTGGCTC CAGAAGCGAG CGCCGGCTCC ACGGCTTCAG TGCGGCCCAC CCAGGAGGAG 2340 2341 CAGTCGACGA CCCCCCCAGG CAAGGTGGTG ACCATCAGCT CCCGGAGCCC CCGCTGCCCT 2400 2401 CGAAACCAGT CTGCCCTTCG CAACGGCAAG ACCTTCTCCC CCAACTCGGC AGCTTGCTCC 2460 2461 TCAGGTTTGA GAAACCCTCC AAGACCCCTC TTGGTGGCCG GTCCCTCCAG TACAGGAAGC 2520 2521 AGTGACTCAG ATGGCGGCCT TTTTGCTGTC CCAACAACTC TGCCACCCAA CAGCCGACAC 2580 2581 GGGAAGCTCT TCTCTCCCAG TAAAGAAACA GAATTGACTT TCCGTCAGCA TCTGAACTCC 2640 2641 ATCAGCATGC AGTCGGATTT CTTCTTGCCA AAGCCCAGAA AGTTGAGGAA CCGGCACCTG 2700 2701 CGGAAACCGT TGGTGGTCCA GAGAACACTG CTTCCTAGAC CGTCTGAAAA CCAGTCCCAT 2760 2761 AATGTCTGCT CCTTCTCCAT CCTGTCGAAT TCCTCCGTAA CTGGGAGAGG CTCGTTCCGG 2820 2821 CCCATCCAGT CCTCCCTGAC CAAAGCAGCT CTGTCTCGGC CAATCGTGCC CAAGGTCCTT 2880 2881 CCACCCCAGG CTACAGGCCA CCTGGCCAGC GCTATCGACT TAGCAGCTCA GAGTGCCGGC 2940 2941 ATCATCCCTG GGAGCCCCCT GCCTGTCCTG GATGCCGAGG GTCTGCCTGG CATCTCTCCA 3000 3001 CTGTCTGCAG ATGAAGTCAC AGCTGCTGCC TCGGGGCGGG ACTCCACTGG AACCCACCCC 3060 3061 AATGGAGACC CCCTCCCCGC CGTGCGGGGC ACGAGCGACC CATTCATCAG TGTCGCCTCA 3120 3121 AGGCCTGAGC AGGAGCCGGT GACGGACGGT TTCCAGGGTT CGCCTGTTCT CTCCTTATCT 3180 3181 GAGCTGTCCA AGCCTCCTCT CCACAACGGG CTCTCCACAC CTCTGCCCTC ATCGGAGGGC 3240 3241 TCCAGCACCC GGCTCTCTCC GCCCAACGTC TCTGCTCTGC TGGACATTTC CCTGCCTGGC 3300 3301 CCGCCCGAGG ACGTGCTCTC GCAGGGGGAG CCTGCCACGC AGATCAGTGA CTCCATCATC 3360 3361 GAGATTGCCA TCAGCTCTGG CCAGTATGGT GAAGGAGTCC CTCTTTCTCC AGCAAAACTG 3420 3421 AATGGCAGTG ACAGTTCCAA GAGTCTTCCC TCCCCGTCCA GCAGCCCCCA GCCAGACTGG 3480 3481 ATTGCCTCCC CCACCCACGA CCCCCAGTGG TGCCCCAGTG ACCCCACGGA CTCGTCGCTC 3540 3541 AGCAGCTTGT TTGCGAGCTT CATCTCCCCA GAGAAGAGCC GGAAGATGTT GCCAACTCCC 3600 3601 ATCGGGACCA ACAGTGGCAC CTCCCTGCTG GGCCCCAGCC TGCTGGATGG AAACTCGCGA 3660 3661 GACTCATTTG TGTCCAGGTC CCTGGCCGAT GTCGCAGAGG TCGTGGATTC CCAGCTGGTG 3720 3721 TGTATGATGA ATGAAAACAG CATTGATTAC ATATCTCGGT TCAACGATTT GGCCCAAGAA 3780 3781 CTGTCCATCG CCGAGCCCAG CCGCCGAGAG GTTCTGTTTG ATGGTGGTGG AAGTGGCCCT 3840 3841 CCCGTTGGCG ACCTATCCCA GTGA 3864 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Meg-0974 | Meleagris gallopavo | 90.82 | 5e-40 | 166 |
| LLPS-Aim-0628 | Ailuropoda melanoleuca | 90.78 | 0.0 | 1755 |
| LLPS-Caf-0746 | Canis familiaris | 89.8 | 0.0 | 1758 |
| LLPS-Man-1165 | Macaca nemestrina | 89.09 | 2e-21 | 105 |
| LLPS-Mup-0459 | Mustela putorius furo | 89.01 | 0.0 | 1649 |
| LLPS-Urm-0577 | Ursus maritimus | 88.47 | 0.0 | 1682 |
| LLPS-Bot-0506 | Bos taurus | 88.03 | 0.0 | 1753 |
| LLPS-Sus-0638 | Sus scrofa | 87.59 | 0.0 | 1683 |
| LLPS-Fec-0654 | Felis catus | 87.25 | 0.0 | 1708 |
| LLPS-Mal-2244 | Mandrillus leucophaeus | 86.01 | 0.0 | 1650 |
| LLPS-Cas-2030 | Carlito syrichta | 85.93 | 0.0 | 1656 |
| LLPS-Poa-1972 | Pongo abelii | 85.66 | 0.0 | 1668 |
| LLPS-Mam-1123 | Macaca mulatta | 85.55 | 0.0 | 1697 |
| LLPS-Maf-0365 | Macaca fascicularis | 85.47 | 0.0 | 1696 |
| LLPS-Chs-2323 | Chlorocebus sabaeus | 85.47 | 0.0 | 1727 |
| LLPS-Cea-3671 | Cercocebus atys | 85.47 | 0.0 | 1696 |
| LLPS-Rhb-1905 | Rhinopithecus bieti | 85.47 | 0.0 | 1694 |
| LLPS-Hos-2250 | Homo sapiens | 85.39 | 0.0 | 1696 |
| LLPS-Gog-1410 | Gorilla gorilla | 85.32 | 0.0 | 1688 |
| LLPS-Myl-0517 | Myotis lucifugus | 85.31 | 0.0 | 1704 |
| LLPS-Pat-1286 | Pan troglodytes | 85.16 | 0.0 | 1692 |
| LLPS-Caj-0185 | Callithrix jacchus | 84.23 | 0.0 | 1702 |
| LLPS-Pap-2189 | Pan paniscus | 84.16 | 0.0 | 1679 |
| LLPS-Dio-2698 | Dipodomys ordii | 83.49 | 0.0 | 1594 |
| LLPS-Paa-1003 | Papio anubis | 83.47 | 0.0 | 1652 |
| LLPS-Ora-3581 | Ornithorhynchus anatinus | 83.26 | 0.0 | 627 |
| LLPS-Orc-1708 | Oryctolagus cuniculus | 82.88 | 0.0 | 1604 |
| LLPS-Nol-0418 | Nomascus leucogenys | 82.5 | 0.0 | 1573 |
| LLPS-Fud-2968 | Fukomys damarensis | 82.23 | 0.0 | 1716 |
| LLPS-Aon-0900 | Aotus nancymaae | 82.08 | 0.0 | 1545 |
| LLPS-Ict-1619 | Ictidomys tridecemlineatus | 81.66 | 0.0 | 1664 |
| LLPS-Otg-2067 | Otolemur garnettii | 81.59 | 0.0 | 1674 |
| LLPS-Ran-0155 | Rattus norvegicus | 81.45 | 0.0 | 1652 |
| LLPS-Mum-3490 | Mus musculus | 81.39 | 0.0 | 1655 |
| LLPS-Cap-2664 | Cavia porcellus | 80.96 | 0.0 | 1701 |
| LLPS-Mea-2238 | Mesocricetus auratus | 79.04 | 0.0 | 1602 |
| LLPS-Loa-0615 | Loxodonta africana | 77.85 | 0.0 | 1532 |
| LLPS-Mod-1540 | Monodelphis domestica | 76.59 | 0.0 | 1595 |
| LLPS-Sah-1388 | Sarcophilus harrisii | 75.68 | 0.0 | 1585 |
| LLPS-Icp-0179 | Ictalurus punctatus | 73.01 | 1e-143 | 468 |
| LLPS-Scf-3181 | Scleropages formosus | 72.67 | 3e-141 | 467 |
| LLPS-Lac-1170 | Latimeria chalumnae | 72.65 | 0.0 | 625 |
| LLPS-Gaga-2312 | Gallus gallus | 69.56 | 0.0 | 1486 |
| LLPS-Pes-0423 | Pelodiscus sinensis | 69.55 | 0.0 | 1442 |
| LLPS-Tag-1484 | Taeniopygia guttata | 69.1 | 0.0 | 1442 |
| LLPS-Leo-0841 | Lepisosteus oculatus | 68.66 | 4e-167 | 538 |
| LLPS-Fia-0963 | Ficedula albicollis | 68.59 | 0.0 | 1462 |
| LLPS-Anc-1246 | Anolis carolinensis | 68.51 | 0.0 | 1320 |
| LLPS-Orn-0135 | Oreochromis niloticus | 67.38 | 3e-156 | 506 |
| LLPS-Dar-1641 | Danio rerio | 66.01 | 4e-163 | 521 |
| LLPS-Anp-0108 | Anas platyrhynchos | 65.97 | 0.0 | 1192 |
| LLPS-Gaa-1565 | Gasterosteus aculeatus | 65.7 | 2e-154 | 490 |
| LLPS-Xim-0784 | Xiphophorus maculatus | 65.54 | 6e-151 | 493 |
| LLPS-Scm-0811 | Scophthalmus maximus | 65.17 | 3e-149 | 489 |
| LLPS-Orl-0198 | Oryzias latipes | 64.43 | 2e-151 | 494 |
| LLPS-Pof-1229 | Poecilia formosa | 64.43 | 9e-151 | 493 |
| LLPS-Asm-0730 | Astyanax mexicanus | 64.14 | 7e-147 | 476 |
| LLPS-Tar-2674 | Takifugu rubripes | 62.84 | 4e-153 | 499 |
| LLPS-Xet-3346 | Xenopus tropicalis | 60.44 | 0.0 | 1159 |
| LLPS-Cii-1133 | Ciona intestinalis | 53.06 | 1e-23 | 106 |
| LLPS-Drm-0202 | Drosophila melanogaster | 42.59 | 2e-44 | 179 |
| LLPS-Sem-0781 | Selaginella moellendorffii | 31.73 | 1e-08 | 63.5 |
| LLPS-Orm-1395 | Oryza meridionalis | 29.7 | 5e-07 | 58.9 |
| LLPS-Cae-0249 | Caenorhabditis elegans | 25.98 | 9e-13 | 77.0 |