• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-0255
VDAC1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Voltage dependent anion channel 1
Gene Name: VDAC1
Ensembl Gene: ENSECAG00000012365.2
Ensembl Protein: ENSECAP00000037800.1
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVGMRKTAEK  AEGEATPAQQ  PGAFREESHP  PVLLGGCHLR  SGSGVGSTQP  VVPVHLLCQE  60
61    LCWSRRESLA  LSELPCPWMR  KMAVPPTYAD  LGKSARDVFT  KGYGFGLIKL  DLKTKSENGL  120
121   EFTSSGSANT  ETTKVTGSLE  TKYRWTEYGL  TFTEKWNTDN  TLGTEITVED  QLARGLKLTF  180
181   DSSFSPNTGK  KNAKIKTGYK  REHINLGCDV  DFDIAGPSIR  GALVLGYEGW  LAGYQMNFET  240
241   AKSRVTQSNF  AVGYKTDEFQ  LHTNVNDGTE  FGGSIYQKVN  KKLETAVNLA  WTAGNSNTRF  300
301   GIAAKYQIDP  DACFSVGTGG  ILLDCWSSLL  WLDVFSLWKE  FELSKTIIVT  VLPMGARHCV  360
361   EPIVGGVLYL  ICTQPIWGRC  LFVF  384
Nucleotide CDS Sequence (FASTA)
1     ATGGTGGGGA  TGAGGAAGAC  TGCAGAAAAG  GCAGAAGGGG  AAGCTACACC  CGCACAGCAG  60
61    CCCGGGGCCT  TTAGGGAGGA  GAGTCATCCT  CCTGTTCTCC  TTGGCGGGTG  TCATCTCAGG  120
121   TCTGGGAGTG  GAGTTGGCTC  CACTCAGCCA  GTGGTTCCTG  TGCATCTTCT  CTGCCAGGAG  180
181   CTGTGCTGGA  GTCGCAGGGA  GAGCCTGGCC  TTATCTGAGC  TCCCTTGTCC  TTGGATGCGG  240
241   AAGATGGCTG  TGCCTCCCAC  CTACGCTGAT  CTTGGCAAAT  CCGCCAGGGA  CGTCTTCACC  300
301   AAGGGCTATG  GATTTGGCTT  AATAAAACTT  GATTTGAAAA  CAAAATCTGA  GAATGGACTG  360
361   GAATTTACAA  GCTCAGGTTC  AGCCAACACT  GAGACCACCA  AAGTGACGGG  CAGTCTAGAA  420
421   ACCAAGTACA  GATGGACCGA  ATATGGTCTG  ACGTTTACAG  AGAAATGGAA  CACCGACAAC  480
481   ACACTAGGCA  CGGAGATTAC  TGTGGAAGAC  CAGCTTGCAC  GTGGACTGAA  GCTGACCTTT  540
541   GATTCATCCT  TCTCACCAAA  CACTGGGAAA  AAAAATGCTA  AGATCAAGAC  AGGGTACAAA  600
601   CGAGAGCACA  TCAACCTGGG  CTGCGACGTG  GACTTCGACA  TCGCAGGGCC  TTCAATCCGG  660
661   GGCGCCCTGG  TGCTGGGTTA  TGAGGGTTGG  CTGGCTGGCT  ACCAGATGAA  TTTTGAGACC  720
721   GCGAAGTCTC  GAGTGACCCA  GAGCAACTTT  GCGGTTGGCT  ACAAGACTGA  TGAATTCCAG  780
781   CTTCACACTA  ATGTAAACGA  TGGGACAGAG  TTTGGCGGCT  CCATTTATCA  GAAGGTGAAC  840
841   AAGAAGTTGG  AGACTGCTGT  TAATCTCGCC  TGGACAGCAG  GAAACAGTAA  CACTCGCTTC  900
901   GGAATAGCAG  CCAAGTATCA  GATCGACCCT  GACGCGTGCT  TCTCGGTGGG  TACTGGTGGA  960
961   ATCCTTCTGG  ATTGCTGGAG  TTCCCTGCTT  TGGCTAGATG  TTTTCTCACT  GTGGAAAGAA  1020
1021  TTCGAATTGA  GTAAAACAAT  AATAGTAACG  GTACTTCCTA  TGGGTGCCAG  GCACTGTGTG  1080
1081  GAGCCCATTG  TTGGTGGGGT  ACTCTATTTA  ATTTGTACAC  AACCCATTTG  GGGTAGGTGC  1140
1141  CTTTTTGTTT  TTTAA  1155

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-0222Macaca nemestrina99.583e-169 483
LLPS-Ova-3105Ovis aries99.571e-169 483
LLPS-Orc-2539Oryctolagus cuniculus99.571e-169 483
LLPS-Ict-1134Ictidomys tridecemlineatus99.161e-170 485
LLPS-Tut-2029Tursiops truncatus99.151e-168 480
LLPS-Fec-2475Felis catus99.153e-168 479
LLPS-Hos-1952Homo sapiens99.155e-169 481
LLPS-Chs-3056Chlorocebus sabaeus98.758e-170 483
LLPS-Bot-0102Bos taurus98.741e-170 485
LLPS-Caf-1870Canis familiaris98.746e-171 486
LLPS-Otg-0529Otolemur garnettii98.746e-171 486
LLPS-Dio-0180Dipodomys ordii98.736e-170 484
LLPS-Mal-1430Mandrillus leucophaeus98.732e-169 483
LLPS-Sus-0930Sus scrofa98.733e-170 484
LLPS-Fud-1787Fukomys damarensis98.738e-170 483
LLPS-Mam-1893Macaca mulatta98.738e-169 482
LLPS-Mup-0699Mustela putorius furo98.727e-169 481
LLPS-Caj-2520Callithrix jacchus98.721e-168 480
LLPS-Cap-3918Cavia porcellus98.723e-168 479
LLPS-Nol-4311Nomascus leucogenys98.724e-166 474
LLPS-Urm-0024Ursus maritimus98.726e-169 481
LLPS-Paa-2057Papio anubis98.322e-170 485
LLPS-Maf-2692Macaca fascicularis98.326e-170 484
LLPS-Gog-2824Gorilla gorilla98.322e-170 485
LLPS-Pat-1607Pan troglodytes98.322e-170 485
LLPS-Aon-3200Aotus nancymaae98.312e-169 482
LLPS-Ran-4510Rattus norvegicus98.35e-168 479
LLPS-Cas-0175Carlito syrichta97.912e-168 480
LLPS-Aim-1035Ailuropoda melanoleuca97.519e-170 483
LLPS-Mum-3927Mus musculus97.472e-167 478
LLPS-Loa-0663Loxodonta africana97.072e-166 474
LLPS-Myl-2314Myotis lucifugus96.642e-167 478
LLPS-Cea-3817Cercocebus atys96.585e-161 461
LLPS-Rhb-3566Rhinopithecus bieti95.936e-170 484
LLPS-Mod-2048Monodelphis domestica94.478e-163 465
LLPS-Sah-1479Sarcophilus harrisii94.092e-163 467
LLPS-Pes-0981Pelodiscus sinensis93.624e-160 458
LLPS-Anp-0603Anas platyrhynchos92.837e-161 461
LLPS-Ora-0662Ornithorhynchus anatinus92.771e-159 457
LLPS-Tag-1788Taeniopygia guttata92.413e-161 461
LLPS-Fia-3062Ficedula albicollis91.916e-159 455
LLPS-Gaga-1790Gallus gallus91.432e-162 465
LLPS-Leo-0420Lepisosteus oculatus91.069e-156 448
LLPS-Pap-2449Pan paniscus91.069e-151 434
LLPS-Meg-1865Meleagris gallopavo90.614e-157 451
LLPS-Anc-1957Anolis carolinensis88.713e-159 458
LLPS-Scf-3075Scleropages formosus88.093e-151 436
LLPS-Xet-3349Xenopus tropicalis88.091e-154 444
LLPS-Asm-2611Astyanax mexicanus86.813e-150 433
LLPS-Scm-1771Scophthalmus maximus86.382e-139 406
LLPS-Orn-1664Oreochromis niloticus86.384e-140 408
LLPS-Orl-0029Oryzias latipes85.113e-146 424
LLPS-Ten-0728Tetraodon nigroviridis85.112e-145 422
LLPS-Lac-3373Latimeria chalumnae84.942e-143 417
LLPS-Dar-0424Danio rerio84.264e-146 423
LLPS-Pof-3605Poecilia formosa84.269e-142 412
LLPS-Tar-3281Takifugu rubripes83.671e-115 346
LLPS-Xim-1144Xiphophorus maculatus83.41e-140 409
LLPS-Gaa-3667Gasterosteus aculeatus82.984e-142 413
LLPS-Poa-2197Pongo abelii82.258e-129 377
LLPS-Mea-3376Mesocricetus auratus81.482e-144 420
LLPS-Icp-3550Ictalurus punctatus77.022e-135 395
LLPS-Cii-0513Ciona intestinalis57.875e-97 298
LLPS-Cis-0657Ciona savignyi57.451e-93 289
LLPS-Drm-1166Drosophila melanogaster56.965e-93 287
LLPS-Cae-1315Caenorhabditis elegans39.579e-53 183
LLPS-Fus-1358Fusarium solani35.121e-2198.6
LLPS-Phn-0213Phaeosphaeria nodorum34.593e-1782.4
LLPS-Trr-0003Trichoderma reesei34.54e-28 116
LLPS-Nef-0141Neosartorya fischeri33.762e-30 122
LLPS-Asc-0877Aspergillus clavatus33.333e-1991.7
LLPS-Pyt-0320Pyrenophora teres33.051e-27 115
LLPS-Abg-0293Absidia glauca33.051e-31 126
LLPS-Trv-1496Trichoderma virens32.896e-28 115
LLPS-Cogr-0588Colletotrichum graminicola32.799e-28 115
LLPS-Mao-1510Magnaporthe oryzae32.753e-27 113
LLPS-Mel-0772Melampsora laricipopulina32.674e-31 125
LLPS-Lem-0750Leptosphaeria maculans32.472e-28 117
LLPS-Fuv-0963Fusarium verticillioides32.461e-27 115
LLPS-Fuo-1335Fusarium oxysporum32.461e-27 115
LLPS-Pytr-0247Pyrenophora triticirepentis32.342e-25 108
LLPS-Nec-1159Neurospora crassa32.337e-27 112
LLPS-Gag-1096Gaeumannomyces graminis32.311e-26 112
LLPS-Ved-0911Verticillium dahliae32.311e-27 114
LLPS-Asn-0811Aspergillus nidulans32.224e-31 125
LLPS-Crn-1079Cryptococcus neoformans31.934e-29 119
LLPS-Kop-0934Komagataella pastoris31.785e-25 107
LLPS-Beb-1211Beauveria bassiana31.589e-27 112
LLPS-Aso-0860Aspergillus oryzae31.143e-1991.7
LLPS-Asf-0639Aspergillus flavus31.143e-1991.7
LLPS-Put-1147Puccinia triticina31.111e-31 126
LLPS-Tum-0948Tuber melanosporum30.774e-29 119
LLPS-Blg-0300Blumeria graminis30.71e-25 108
LLPS-Map-0116Magnaporthe poae30.76e-26 110
LLPS-Pug-0838Puccinia graminis30.675e-31 124
LLPS-Miv-0091Microbotryum violaceum30.293e-28 117
LLPS-Spr-0494Sporisorium reilianum29.491e-28 118
LLPS-Prp-2007Prunus persica29.245e-1063.5
LLPS-Usm-1193Ustilago maydis28.933e-29 119
LLPS-Glm-1368Glycine max28.764e-1064.3
LLPS-Coc-0652Corchorus capsularis28.75e-1063.9
LLPS-Chr-1663Chlamydomonas reinhardtii28.572e-1065.1
LLPS-Scc-0749Schizosaccharomyces cryophilus28.577e-26 110
LLPS-Amt-1582Amborella trichopoda28.573e-1270.5
LLPS-Yal-0484Yarrowia lipolytica28.453e-28 116
LLPS-Ast-1093Aspergillus terreus28.364e-2299.4
LLPS-Scp-0851Schizosaccharomyces pombe27.392e-23 102
LLPS-Scj-1294Schizosaccharomyces japonicus27.399e-24 103
LLPS-Coo-0667Colletotrichum orbiculare27.363e-2094.0
LLPS-Gor-2001Gossypium raimondii27.074e-1063.9
LLPS-Cog-0387Colletotrichum gloeosporioides26.873e-1682.4
LLPS-Asg-1348Ashbya gossypii26.691e-1993.2
LLPS-Gas-0374Galdieria sulphuraria26.437e-1167.0
LLPS-Asfu-1319Aspergillus fumigatus26.372e-2197.4
LLPS-Zyt-0537Zymoseptoria tritici25.05e-1579.0
LLPS-Tra-2114Triticum aestivum23.662e-1065.5
LLPS-Dos-1054Dothistroma septosporum23.489e-1475.1
LLPS-Sac-0127Saccharomyces cerevisiae22.981e-1271.6