DrLLPS - Data resource of LLPS

LLPS-Drm-2296
P5cr

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Pyrroline-5-carboxylate reductase
Gene Name:	P5cr, Dmel\CG6009, P5CR, CG6009, Dmel_CG6009
Ensembl Gene:	FBgn0015781
Ensembl Protein:	FBpp0083127
Organism:	Drosophila melanogaster
Taxa ID:	7227
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0471	P32263	Client	Stress granule	46.89	1e-61	233

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	FBtr0083713	FBpp0083127
UniProt		Q9V3F8, Q9V3F8_DROME
GeneBank	AE014297, AF170829	AAF55626.1, AAD49740.1
RefSeq	NM_079676.4	NP_524400.2
Entrez	42284

▼ SEQUENCE

Protein Sequence (FASTA)
1 MAKLDEKIGF IGGGNMAYAI GSGLVRCGIV KASQVQVSGP HIENLQRWRD LGAVTCDDNC 60 61 MVLEHSDIVF ICVKPHMLTP CAAQLKYKHV PSAKDASKLV VSVLAGTSLE TLEEAFSFMG 120 121 SSELKVIRTM PNTSMQVGEG CTVYTGNARV SHHDLEKIHL MLNALGLAQQ VPESMIDAVT 180 181 GVAGCGPAFV YTIIEALADG GVKQGVPRQM ALQFAAQTLL GAAKTVLLTG KHPAVLRDEV 240 241 CSPGGATIVG VHELEKGNLR STLINAVEKS SQRSAELGKK 280
Nucleotide CDS Sequence (FASTA)
1 ATGGCCAAGT TGGACGAAAA GATCGGCTTC ATCGGGGGCG GAAACATGGC CTACGCCATA 60 61 GGATCCGGAC TGGTGCGCTG TGGGATCGTG AAGGCTAGCC AGGTGCAGGT CTCCGGTCCC 120 121 CACATTGAGA ACCTGCAACG GTGGCGGGAT CTGGGAGCTG TGACCTGCGA CGACAACTGC 180 181 ATGGTCCTGG AGCACTCGGA CATAGTTTTC ATCTGCGTAA AGCCACACAT GCTAACGCCG 240 241 TGTGCCGCCC AGCTTAAATA CAAGCACGTG CCGTCGGCCA AGGATGCCAG CAAGCTGGTG 300 301 GTGTCGGTTC TGGCGGGTAC CAGTCTCGAA ACGCTGGAGG AGGCCTTCAG CTTCATGGGC 360 361 AGTTCGGAGC TGAAGGTGAT ACGCACCATG CCCAATACAT CCATGCAGGT GGGCGAGGGC 420 421 TGCACTGTTT ACACTGGCAA CGCACGCGTT TCGCATCACG ACTTGGAAAA GATTCACCTA 480 481 ATGCTCAACG CCCTGGGACT GGCGCAACAG GTGCCCGAGT CCATGATCGA CGCCGTTACC 540 541 GGGGTAGCTG GATGCGGTCC GGCATTTGTT TACACCATCA TAGAGGCACT GGCCGATGGC 600 601 GGCGTCAAAC AGGGCGTTCC GCGTCAGATG GCTCTTCAGT TTGCGGCTCA GACGCTTCTG 660 661 GGAGCGGCCA AAACGGTGCT GCTCACTGGA AAACATCCGG CGGTGCTGCG GGATGAAGTC 720 721 TGTTCTCCCG GTGGCGCCAC CATAGTAGGC GTTCATGAAC TGGAAAAGGG GAACCTCAGG 780 781 TCTACTTTAA TAAACGCCGT GGAAAAGTCG TCACAGCGCT CTGCTGAACT GGGAAAGAAG 840

▼ ANNOTATION

Disorder
D²P²	IUPred2A

Domain
SMART	CDD	Gene3D

PTM
PTMcode

Interaction
HINT	RAIN	Mentha	PINA	IID
iRefIndex	MIST

Physicochemical
AAindex

Localization
COMPARTMENTS

Expression
ArrayExpress

Element
RAID	microRNA.org

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Anp-2422	Anas platyrhynchos	50.98	9e-44	154
LLPS-Mae-2387	Manihot esculenta	50.39	4e-37	134
LLPS-Sot-1551	Solanum tuberosum	43.17	5e-66	214
LLPS-Pes-3432	Pelodiscus sinensis	43.14	3e-58	193
LLPS-Leo-0068	Lepisosteus oculatus	42.75	8e-62	203
LLPS-Asm-3188	Astyanax mexicanus	42.7	1e-60	200
LLPS-Ere-0152	Erinaceus europaeus	42.62	4e-48	166
LLPS-Caj-2991	Callithrix jacchus	42.55	2e-60	199
LLPS-Arl-2104	Arabidopsis lyrata	42.39	1e-63	207
LLPS-Orn-2825	Oreochromis niloticus	42.34	9e-62	203
LLPS-Urm-1235	Ursus maritimus	42.31	2e-52	179
LLPS-Ora-3278	Ornithorhynchus anatinus	42.29	3e-52	177
LLPS-Nia-2158	Nicotiana attenuata	42.18	3e-65	212
LLPS-Hea-2016	Helianthus annuus	42.12	3e-62	204
LLPS-Sol-1855	Solanum lycopersicum	42.12	1e-63	208
LLPS-Prp-2554	Prunus persica	42.12	4e-62	204
LLPS-Coc-0658	Corchorus capsularis	42.03	1e-58	195
LLPS-Art-2757	Arabidopsis thaliana	42.03	5e-63	206
LLPS-Gaa-2991	Gasterosteus aculeatus	41.97	9e-63	210
LLPS-Eqc-3430	Equus caballus	41.61	5e-60	199
LLPS-Vir-2188	Vigna radiata	41.54	2e-60	199
LLPS-Gas-1281	Galdieria sulphuraria	41.54	7e-57	190
LLPS-Lac-2064	Latimeria chalumnae	41.54	5e-61	203
LLPS-Mua-2352	Musa acuminata	41.39	7e-64	208
LLPS-Glm-2509	Glycine max	41.39	5e-60	198
LLPS-Cas-4001	Carlito syrichta	41.37	2e-57	192
LLPS-Hov-0487	Hordeum vulgare	41.3	2e-62	205
LLPS-Thc-0857	Theobroma cacao	41.3	3e-60	199
LLPS-Caf-4099	Canis familiaris	41.3	5e-62	205
LLPS-Ten-2263	Tetraodon nigroviridis	41.24	6e-61	201
LLPS-Anc-3872	Anolis carolinensis	41.22	2e-63	207
LLPS-Via-1876	Vigna angularis	41.18	2e-60	199
LLPS-Cii-0785	Ciona intestinalis	41.18	7e-61	201
LLPS-Chs-3201	Chlorocebus sabaeus	41.09	4e-58	194
LLPS-Rhb-0100	Rhinopithecus bieti	41.09	6e-58	193
LLPS-Pot-0874	Populus trichocarpa	41.09	1e-58	194
LLPS-Dac-0411	Daucus carota	41.03	1e-63	208
LLPS-Gaga-3129	Gallus gallus	41.03	6e-64	208
LLPS-Tra-1230	Triticum aestivum	40.94	6e-62	204
LLPS-Dio-2769	Dipodomys ordii	40.94	1e-56	189
LLPS-Otg-2861	Otolemur garnettii	40.94	2e-62	206
LLPS-Brr-2264	Brassica rapa	40.88	2e-60	199
LLPS-Fia-1393	Ficedula albicollis	40.81	8e-62	203
LLPS-Paa-0907	Papio anubis	40.73	1e-56	189
LLPS-Myl-1697	Myotis lucifugus	40.73	3e-58	194
LLPS-Gog-0328	Gorilla gorilla	40.73	2e-57	192
LLPS-Nol-4523	Nomascus leucogenys	40.73	2e-57	192
LLPS-Hos-3105	Homo sapiens	40.73	2e-57	192
LLPS-Pat-4433	Pan troglodytes	40.73	2e-57	192
LLPS-Sem-1818	Selaginella moellendorffii	40.66	3e-62	204
LLPS-Viv-1678	Vitis vinifera	40.59	8e-60	198
LLPS-Cae-2073	Caenorhabditis elegans	40.58	1e-62	205
LLPS-Fec-2145	Felis catus	40.58	2e-62	206
LLPS-Aim-1994	Ailuropoda melanoleuca	40.51	3e-56	189
LLPS-Gor-0297	Gossypium raimondii	40.43	5e-60	198
LLPS-Brd-0205	Brachypodium distachyon	40.36	5e-61	201
LLPS-Meg-3257	Meleagris gallopavo	40.29	7e-58	193
LLPS-Ova-1448	Ovis aries	40.22	5e-62	205
LLPS-Cus-0967	Cucumis sativus	40.22	2e-57	192
LLPS-Cis-1392	Ciona savignyi	40.22	1e-67	218
LLPS-Aon-0784	Aotus nancymaae	40.22	7e-62	204
LLPS-Ict-0878	Ictidomys tridecemlineatus	40.22	2e-61	203
LLPS-Brn-0171	Brassica napus	40.15	6e-61	201
LLPS-Tru-1537	Triticum urartu	40.15	6e-48	167
LLPS-Bro-0931	Brassica oleracea	40.15	8e-61	200
LLPS-Loa-2877	Loxodonta africana	40.14	9e-59	196
LLPS-Met-1422	Medicago truncatula	40.07	8e-58	192
LLPS-Fud-3311	Fukomys damarensis	40.07	9e-61	201
LLPS-Xet-2320	Xenopus tropicalis	40.07	6e-57	192
LLPS-Phv-1024	Phaseolus vulgaris	40.07	2e-59	197
LLPS-Orc-3656	Oryctolagus cuniculus	40.0	3e-50	174
LLPS-Bot-2404	Bos taurus	39.93	2e-55	189
LLPS-Pap-1261	Pan paniscus	39.92	2e-47	166
LLPS-Mup-2992	Mustela putorius furo	39.86	5e-59	197
LLPS-Mum-3646	Mus musculus	39.86	2e-61	203
LLPS-Mea-1147	Mesocricetus auratus	39.86	3e-61	202
LLPS-Poa-1861	Pongo abelii	39.86	7e-61	202
LLPS-Cap-0640	Cavia porcellus	39.86	2e-61	203
LLPS-Mod-3780	Monodelphis domestica	39.86	3e-62	205
LLPS-Ran-1559	Rattus norvegicus	39.78	1e-60	202
LLPS-Tar-2057	Takifugu rubripes	39.71	1e-58	196
LLPS-Amt-1766	Amborella trichopoda	39.71	1e-55	187
LLPS-Dar-3987	Danio rerio	39.71	1e-57	194
LLPS-Orbr-0885	Oryza brachyantha	39.64	9e-58	193
LLPS-Orp-0459	Oryza punctata	39.64	2e-57	193
LLPS-Ors-2318	Oryza sativa	39.56	9e-57	190
LLPS-Mal-3827	Mandrillus leucophaeus	39.49	2e-58	196
LLPS-Sus-0444	Sus scrofa	39.49	5e-61	202
LLPS-Sah-0865	Sarcophilus harrisii	39.49	2e-60	201
LLPS-Cea-1566	Cercocebus atys	39.49	3e-58	196
LLPS-Maf-3528	Macaca fascicularis	39.49	2e-58	196
LLPS-Mam-2645	Macaca mulatta	39.49	7e-58	195
LLPS-Man-3341	Macaca nemestrina	39.49	7e-58	195
LLPS-Osl-0923	Ostreococcus lucimarinus	39.42	1e-57	192
LLPS-Icp-3526	Ictalurus punctatus	39.34	1e-57	193
LLPS-Org-1728	Oryza glaberrima	39.27	2e-57	192
LLPS-Tut-0088	Tursiops truncatus	39.05	4e-57	192
LLPS-Xim-0811	Xiphophorus maculatus	38.97	4e-57	192
LLPS-Orl-1866	Oryzias latipes	38.97	1e-57	194
LLPS-Pof-0861	Poecilia formosa	38.97	3e-57	192
LLPS-Orr-1343	Oryza rufipogon	38.91	3e-56	191
LLPS-Sei-1266	Setaria italica	38.83	1e-57	193
LLPS-Lep-0418	Leersia perrieri	38.69	1e-54	187
LLPS-Php-2063	Physcomitrella patens	38.69	1e-54	186
LLPS-Scf-1346	Scleropages formosus	38.6	2e-56	191
LLPS-Scm-2016	Scophthalmus maximus	38.6	2e-57	193
LLPS-Zem-0672	Zea mays	38.46	5e-58	193
LLPS-Cym-1125	Cyanidioschyzon merolae	38.27	2e-47	166
LLPS-Mel-0266	Melampsora laricipopulina	38.17	2e-42	153
LLPS-Sob-0175	Sorghum bicolor	38.1	7e-58	193
LLPS-Chr-0842	Chlamydomonas reinhardtii	37.68	2e-56	191
LLPS-Yal-1155	Yarrowia lipolytica	37.56	2e-34	132
LLPS-Tag-2741	Taeniopygia guttata	37.5	3e-50	174
LLPS-Miv-0670	Microbotryum violaceum	37.45	2e-38	143
LLPS-Usm-0988	Ustilago maydis	36.84	2e-37	140
LLPS-Crn-0257	Cryptococcus neoformans	36.65	6e-37	139
LLPS-Spr-0349	Sporisorium reilianum	36.52	1e-37	140
LLPS-Chc-0664	Chondrus crispus	36.07	7e-46	164
LLPS-Scp-0334	Schizosaccharomyces pombe	35.71	4e-40	146
LLPS-Scc-0466	Schizosaccharomyces cryophilus	35.66	2e-40	147
LLPS-Pug-1149	Puccinia graminis	35.54	2e-32	127
LLPS-Tum-0956	Tuber melanosporum	35.35	2e-31	124
LLPS-Beb-0599	Beauveria bassiana	35.19	1e-29	119
LLPS-Orni-1153	Oryza nivara	34.18	3e-38	140
LLPS-Scj-0783	Schizosaccharomyces japonicus	34.16	2e-28	116
LLPS-Asni-1003	Aspergillus niger	33.94	6e-44	157
LLPS-Kop-0304	Komagataella pastoris	33.92	6e-29	116
LLPS-Nec-1518	Neurospora crassa	33.81	6e-25	106
LLPS-Mao-0647	Magnaporthe oryzae	33.62	2e-27	113
LLPS-Fuv-0421	Fusarium verticillioides	33.57	8e-42	151
LLPS-Fuo-0154	Fusarium oxysporum	33.57	2e-41	150
LLPS-Asf-0814	Aspergillus flavus	33.49	2e-25	107
LLPS-Aso-1353	Aspergillus oryzae	33.49	2e-25	107
LLPS-Pyt-1534	Pyrenophora teres	33.48	2e-31	124
LLPS-Coo-0943	Colletotrichum orbiculare	33.47	3e-28	115
LLPS-Ast-0870	Aspergillus terreus	33.45	7e-31	122
LLPS-Asc-1533	Aspergillus clavatus	33.33	1e-38	142
LLPS-Map-1089	Magnaporthe poae	33.19	2e-29	118
LLPS-Gag-1328	Gaeumannomyces graminis	33.19	3e-29	118
LLPS-Asfu-0809	Aspergillus fumigatus	33.09	3e-38	142
LLPS-Nef-1476	Neosartorya fischeri	33.09	5e-38	141
LLPS-Cogr-0682	Colletotrichum graminicola	33.05	4e-26	109
LLPS-Cog-0226	Colletotrichum gloeosporioides	33.05	7e-27	112
LLPS-Pytr-1540	Pyrenophora triticirepentis	33.04	2e-31	124
LLPS-Phn-0422	Phaeosphaeria nodorum	32.26	4e-19	89.0
LLPS-Scs-0934	Sclerotinia sclerotiorum	32.19	4e-37	139
LLPS-Sac-0471	Saccharomyces cerevisiae	31.86	1e-30	121
LLPS-Trr-0988	Trichoderma reesei	31.77	1e-37	140
LLPS-Dos-1467	Dothistroma septosporum	31.53	1e-25	107
LLPS-Zyt-0474	Zymoseptoria tritici	31.42	2e-26	109
LLPS-Abg-1728	Absidia glauca	31.1	2e-29	118
LLPS-Put-0029	Puccinia triticina	31.09	5e-30	120
LLPS-Asn-1303	Aspergillus nidulans	30.97	3e-23	100
LLPS-Trv-1406	Trichoderma virens	30.77	8e-26	108
LLPS-Fus-1491	Fusarium solani	30.58	2e-34	131
LLPS-Asg-0993	Ashbya gossypii	30.09	7e-30	119
LLPS-Lem-0606	Leptosphaeria maculans	29.47	6e-30	120
LLPS-Ved-0652	Verticillium dahliae	29.17	2e-20	92.4
LLPS-Ori-1379	Oryza indica	28.78	7e-21	93.6
LLPS-Blg-1133	Blumeria graminis	28.72	1e-26	110

LLPS-Drm-2296P5cr

Protein Sequence

Nucleotide Sequence

LLPS-Drm-2296
P5cr