LLPS-Drm-2017
PpV

▼ OVERVIEW

Status: Unreviewed
Protein Name: Serine/threonine-protein phosphatase 6 catalytic subunit
Gene Name: PpV, PPPV6A, CG12217
Ensembl Gene: FBgn0003139
Ensembl Protein: FBpp0070883
Organism: Drosophila melanogaster
Taxa ID: 7227
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

May be involved in controlling cellularization or in regulating transcription of the genes involved in this process.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGDVDKWIED  VKKCKYLPEN  ELKKLCEMVC  DILLEETNIL  PVSTPVTVCG  DIHGQFYDLE  60
61    QLFRTGGQVP  HTNYIFMGDF  VDRGYYSLET  FTRLLTLKAR  YPSRITLLRG  NHETRQITKV  120
121   YGFFDECFSK  YGNANGWKYC  CKVFDLLTIA  AIIDEEVLCV  HGGLSPEIIT  LDQIRTIDRN  180
181   GEIPYKGAFC  DLVWSDPEDM  EYWGQSPRGA  GWLFGHNVTK  DFMAINNLNL  ICRAHQLVNE  240
241   GIKYMFDGKL  VTVWSAPNYC  YRCGNVAAIL  SFETAEKRQT  KIFLAVPDAE  RVIPKQNTTP  300
301   YFL  303
Nucleotide CDS Sequence (FASTA)
1     ATGGGCGACG  TGGACAAGTG  GATAGAAGAC  GTGAAGAAAT  GCAAGTACCT  GCCGGAGAAC  60
61    GAGCTGAAGA  AGCTATGCGA  GATGGTCTGC  GATATCCTCC  TGGAGGAGAC  GAACATCCTG  120
121   CCCGTGAGCA  CGCCCGTCAC  CGTTTGCGGT  GACATCCATG  GCCAGTTCTA  CGACCTGGAG  180
181   CAGCTGTTCC  GCACTGGAGG  CCAGGTGCCG  CATACCAACT  ACATATTCAT  GGGCGACTTC  240
241   GTGGACAGGG  GCTACTACTC  GCTGGAGACA  TTCACCAGAC  TGCTCACGCT  GAAGGCGCGC  300
301   TATCCCAGCC  GGATCACCCT  GCTGCGCGGC  AACCACGAAA  CGCGGCAGAT  CACCAAGGTG  360
361   TACGGATTCT  TTGACGAGTG  CTTCAGCAAG  TACGGCAATG  CCAATGGCTG  GAAATACTGC  420
421   TGCAAGGTCT  TCGATTTGCT  TACCATCGCT  GCCATCATCG  ACGAGGAGGT  GTTGTGCGTG  480
481   CACGGTGGCC  TGAGTCCCGA  GATCATTACA  CTGGACCAGA  TCAGGACGAT  CGATCGCAAC  540
541   GGCGAGATAC  CGTACAAGGG  TGCCTTCTGC  GATCTGGTGT  GGTCCGATCC  CGAGGACATG  600
601   GAGTACTGGG  GCCAGAGTCC  GCGCGGCGCT  GGCTGGCTGT  TTGGCCACAA  TGTGACCAAG  660
661   GACTTTATGG  CGATCAATAA  TCTGAACCTC  ATATGCCGAG  CACATCAGCT  GGTCAACGAG  720
721   GGCATCAAGT  ATATGTTTGA  TGGCAAACTG  GTGACCGTGT  GGTCGGCGCC  AAACTATTGC  780
781   TATCGCTGCG  GCAACGTTGC  CGCCATTCTT  AGCTTCGAAA  CGGCGGAGAA  GCGGCAGACG  840
841   AAGATCTTCC  TGGCTGTTCC  GGATGCGGAG  CGTGTGATAC  CCAAGCAGAA  CACAACGCCC  900
901   TACTTCCTG  909

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Hydrolase
Manganese
Metal-binding
Protein phosphatase
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Metal ion binding
Molecular Function
Protein serine/threonine phosphatase activity
Biological Process
G1/S transition of mitotic cell cycle
Biological Process
Mitotic cell cycle
Biological Process
Negative regulation of JNK cascade
Biological Process
Protein dephosphorylation

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fia-2734Ficedula albicollis76.711e-144 414
LLPS-Icp-3322Ictalurus punctatus76.716e-128 371
LLPS-Maf-0631Macaca fascicularis76.163e-165 468
LLPS-Scf-3632Scleropages formosus76.088e-178 501
LLPS-Anc-1734Anolis carolinensis76.072e-162 461
LLPS-Urm-0099Ursus maritimus75.899e-163 462
LLPS-Gaga-0317Gallus gallus75.752e-174 502
LLPS-Orn-3918Oreochromis niloticus75.759e-177 498
LLPS-Lac-1580Latimeria chalumnae75.755e-177 499
LLPS-Scm-1533Scophthalmus maximus75.759e-177 498
LLPS-Meg-0327Meleagris gallopavo75.753e-176 497
LLPS-Tar-3248Takifugu rubripes75.753e-177 499
LLPS-Gaa-0494Gasterosteus aculeatus75.759e-177 498
LLPS-Xet-1126Xenopus tropicalis75.421e-176 498
LLPS-Ict-1475Ictidomys tridecemlineatus75.427e-176 496
LLPS-Eqc-3764Equus caballus75.427e-176 496
LLPS-Cap-0963Cavia porcellus75.427e-176 496
LLPS-Poa-1404Pongo abelii75.427e-176 496
LLPS-Otg-3395Otolemur garnettii75.427e-176 496
LLPS-Rhb-1962Rhinopithecus bieti75.427e-176 496
LLPS-Orc-2948Oryctolagus cuniculus75.427e-176 496
LLPS-Fec-0290Felis catus75.427e-176 496
LLPS-Mod-1734Monodelphis domestica75.427e-176 496
LLPS-Dar-3559Danio rerio75.421e-176 498
LLPS-Loa-1335Loxodonta africana75.427e-176 496
LLPS-Ran-1431Rattus norvegicus75.421e-176 498
LLPS-Mup-4312Mustela putorius furo75.427e-176 496
LLPS-Aim-1915Ailuropoda melanoleuca75.427e-176 496
LLPS-Bot-3122Bos taurus75.427e-176 496
LLPS-Fud-3499Fukomys damarensis75.427e-176 496
LLPS-Ora-3050Ornithorhynchus anatinus75.421e-175 498
LLPS-Chs-2136Chlorocebus sabaeus75.427e-176 496
LLPS-Mum-4285Mus musculus75.421e-176 498
LLPS-Sus-0971Sus scrofa75.427e-176 496
LLPS-Sah-2333Sarcophilus harrisii75.352e-166 471
LLPS-Pes-1796Pelodiscus sinensis75.336e-130 376
LLPS-Tag-0597Taeniopygia guttata75.268e-166 470
LLPS-Leo-1173Lepisosteus oculatus75.174e-175 494
LLPS-Pof-4017Poecilia formosa75.082e-175 494
LLPS-Ova-4227Ovis aries75.086e-174 491
LLPS-Tut-1326Tursiops truncatus75.082e-175 495
LLPS-Xim-0661Xiphophorus maculatus75.082e-175 494
LLPS-Asm-2339Astyanax mexicanus75.083e-176 497
LLPS-Orl-2337Oryzias latipes75.081e-176 498
LLPS-Cii-2352Ciona intestinalis74.752e-172 488
LLPS-Caj-3368Callithrix jacchus74.563e-162 462
LLPS-Ten-0200Tetraodon nigroviridis74.59e-172 486
LLPS-Caf-3433Canis familiaris74.426e-173 488
LLPS-Mea-0090Mesocricetus auratus74.425e-172 486
LLPS-Cas-3427Carlito syrichta73.652e-164 467
LLPS-Gas-0081Galdieria sulphuraria71.856e-163 463
LLPS-Amt-1304Amborella trichopoda71.595e-144 415
LLPS-Ere-0718Erinaceus europaeus70.254e-148 424
LLPS-Abg-1333Absidia glauca69.83e-154 442
LLPS-Spr-0062Sporisorium reilianum69.232e-144 418
LLPS-Chc-0013Chondrus crispus68.447e-153 437
LLPS-Mam-2449Macaca mulatta67.883e-165 470
LLPS-Man-0481Macaca nemestrina67.883e-165 470
LLPS-Mal-1867Mandrillus leucophaeus67.883e-165 470
LLPS-Paa-1537Papio anubis67.882e-165 470
LLPS-Scc-0680Schizosaccharomyces cryophilus67.873e-157 449
LLPS-Chr-0165Chlamydomonas reinhardtii67.552e-151 434
LLPS-Scp-0062Schizosaccharomyces pombe67.542e-156 446
LLPS-Aon-0868Aotus nancymaae67.362e-168 478
LLPS-Glm-0202Glycine max67.227e-151 432
LLPS-Nol-1076Nomascus leucogenys67.161e-167 476
LLPS-Pap-1162Pan paniscus67.167e-168 477
LLPS-Pat-0671Pan troglodytes67.167e-168 477
LLPS-Hos-1210Homo sapiens67.167e-168 477
LLPS-Coc-1256Corchorus capsularis66.891e-142 435
LLPS-Prp-2032Prunus persica66.893e-150 431
LLPS-Mae-0658Manihot esculenta66.894e-150 431
LLPS-Phv-0597Phaseolus vulgaris66.896e-150 430
LLPS-Gor-1727Gossypium raimondii66.894e-151 433
LLPS-Pot-2283Populus trichocarpa66.894e-150 431
LLPS-Cus-1354Cucumis sativus66.892e-150 431
LLPS-Met-1222Medicago truncatula66.896e-150 430
LLPS-Vir-1045Vigna radiata66.892e-149 429
LLPS-Via-0347Vigna angularis66.892e-150 431
LLPS-Thc-1081Theobroma cacao66.899e-149 427
LLPS-Sem-0508Selaginella moellendorffii66.892e-151 434
LLPS-Bro-1993Brassica oleracea66.568e-149 427
LLPS-Nia-2304Nicotiana attenuata66.562e-149 429
LLPS-Viv-0320Vitis vinifera66.565e-150 430
LLPS-Scj-0576Schizosaccharomyces japonicus66.561e-152 437
LLPS-Sot-0319Solanum tuberosum66.563e-149 428
LLPS-Php-0271Physcomitrella patens66.565e-149 428
LLPS-Hea-1854Helianthus annuus66.561e-149 429
LLPS-Org-0022Oryza glaberrima66.235e-150 430
LLPS-Orr-0406Oryza rufipogon66.235e-150 430
LLPS-Orbr-0439Oryza brachyantha66.238e-150 430
LLPS-Art-2830Arabidopsis thaliana66.232e-148 426
LLPS-Ors-0855Oryza sativa66.235e-150 430
LLPS-Tra-1365Triticum aestivum66.236e-149 427
LLPS-Arl-1619Arabidopsis lyrata66.236e-149 427
LLPS-Orgl-0102Oryza glumaepatula66.235e-150 430
LLPS-Lep-0556Leersia perrieri66.238e-150 430
LLPS-Orni-0734Oryza nivara66.235e-150 430
LLPS-Sol-0510Solanum lycopersicum66.231e-148 427
LLPS-Orb-1462Oryza barthii66.235e-150 430
LLPS-Orp-1528Oryza punctata65.891e-149 429
LLPS-Brd-1548Brachypodium distachyon65.893e-149 428
LLPS-Hov-0278Hordeum vulgare65.899e-149 427
LLPS-Ori-1310Oryza indica65.899e-149 427
LLPS-Zem-1452Zea mays65.234e-148 426
LLPS-Sob-0511Sorghum bicolor65.234e-148 426
LLPS-Sei-1733Setaria italica65.237e-148 425
LLPS-Myl-2306Myotis lucifugus65.041e-166 474
LLPS-Usm-0694Ustilago maydis64.982e-145 420
LLPS-Sac-1486Saccharomyces cerevisiae64.692e-138 401
LLPS-Cym-0414Cyanidioschyzon merolae64.571e-144 416
LLPS-Crn-0240Cryptococcus neoformans64.569e-141 407
LLPS-Cis-1581Ciona savignyi64.121e-138 400
LLPS-Tum-1194Tuber melanosporum64.057e-140 404
LLPS-Osl-0111Ostreococcus lucimarinus63.042e-141 409
LLPS-Asg-1544Ashbya gossypii62.947e-136 394
LLPS-Cea-4733Cercocebus atys61.653e-148 427
LLPS-Mel-0159Melampsora laricipopulina61.545e-137 399
LLPS-Tru-0212Triticum urartu60.982e-133 389
LLPS-Miv-0805Microbotryum violaceum60.986e-132 384
LLPS-Dio-3972Dipodomys ordii60.22e-138 400
LLPS-Gog-0789Gorilla gorilla60.22e-138 400
LLPS-Orm-0674Oryza meridionalis59.521e-142 413
LLPS-Kop-1294Komagataella pastoris59.221e-134 391
LLPS-Cae-0159Caenorhabditis elegans58.751e-131 385
LLPS-Asni-1343Aspergillus niger58.671e-125 369
LLPS-Pytr-1446Pyrenophora triticirepentis58.382e-139 405
LLPS-Aso-0774Aspergillus oryzae58.071e-130 382
LLPS-Pug-0876Puccinia graminis57.286e-131 382