LLPS-Drm-1782
eIF3j

▼ OVERVIEW

Status: Unreviewed
Protein Name: Eukaryotic translation initiation factor 3 subunit J
Gene Name: eIF3j, Adam, CG12131
Ensembl Gene: FBgn0027619
Ensembl Protein: FBpp0087475
Organism: Drosophila melanogaster
Taxa ID: 7227
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MADDWESAAD  SEVVIRPTAA  ASVNKWEGED  EDEDIKDSWE  DEEEKKDEEK  PTKTEAPAKP  60
61    KPNKALKAKL  EQQALLEEEA  EAKRLANLSP  AEKLAEKLRL  QKIQEASDLK  HAQEAFGVTS  120
121   TCGGLDAFNP  ETKEEFKEFG  ATLSWKVGQF  RESEHFPQFV  EDLVRSLCVN  LSAADIKKVK  180
181   MNVEILHSEK  LKLEKANAKK  PAGKGKGKVT  LRTENDDIDG  YQKYGNDFTE  DYDDFM  236
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGACG  ATTGGGAATC  CGCAGCAGAC  AGCGAGGTGG  TCATCCGGCC  GACTGCCGCC  60
61    GCCAGCGTAA  ACAAGTGGGA  GGGCGAGGAC  GAGGATGAGG  ACATCAAGGA  CAGCTGGGAG  120
121   GATGAGGAGG  AAAAAAAGGA  CGAGGAGAAG  CCTACGAAAA  CAGAAGCACC  AGCCAAACCG  180
181   AAGCCAAATA  AGGCGCTAAA  AGCCAAACTG  GAACAGCAGG  CGCTCCTAGA  GGAGGAAGCG  240
241   GAGGCAAAAC  GTTTGGCCAA  CCTATCGCCT  GCAGAAAAGT  TGGCTGAGAA  GCTGCGATTG  300
301   CAAAAAATCC  AGGAGGCCTC  TGATCTCAAG  CATGCCCAGG  AAGCGTTCGG  TGTGACGAGT  360
361   ACGTGCGGAG  GTCTTGACGC  CTTCAACCCC  GAGACCAAGG  AGGAGTTCAA  GGAATTTGGC  420
421   GCAACGCTCA  GCTGGAAGGT  GGGCCAATTC  CGCGAGTCGG  AGCACTTCCC  CCAATTTGTT  480
481   GAGGATCTGG  TGCGCAGCCT  ATGCGTGAAT  CTGAGCGCTG  CTGACATCAA  AAAGGTCAAG  540
541   ATGAACGTGG  AAATCTTGCA  CTCGGAAAAG  CTGAAGCTGG  AAAAGGCCAA  TGCTAAAAAG  600
601   CCCGCTGGAA  AGGGCAAGGG  CAAGGTCACT  CTCCGCACCG  AAAACGACGA  CATTGACGGT  660
661   TACCAAAAGT  ACGGAAATGA  CTTCACCGAA  GACTATGACG  ACTTCATG  708

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Initiation factor
Protein biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Eukaryotic 43S preinitiation complex
Cellular Component
Eukaryotic 48S preinitiation complex
Cellular Component
Eukaryotic translation initiation factor 3 complex
Molecular Function
Translation initiation factor activity
Biological Process
Formation of cytoplasmic translation initiation complex
Biological Process
Regulation of translational initiation
Biological Process
Translational initiation

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Xet-1097Xenopus tropicalis50.512e-24 103
LLPS-Pof-0530Poecilia formosa47.831e-2092.0
LLPS-Tut-2359Tursiops truncatus46.998e-2088.6
LLPS-Anc-0922Anolis carolinensis46.362e-28 113
LLPS-Tar-1349Takifugu rubripes45.265e-1781.6
LLPS-Xim-0368Xiphophorus maculatus44.685e-1884.3
LLPS-Fia-0767Ficedula albicollis44.674e-28 112
LLPS-Orl-1794Oryzias latipes44.598e-2295.5
LLPS-Ten-1418Tetraodon nigroviridis43.148e-24 100
LLPS-Otg-2849Otolemur garnettii43.057e-25 104
LLPS-Orn-3468Oreochromis niloticus42.863e-2296.3
LLPS-Sah-2183Sarcophilus harrisii41.722e-24 102
LLPS-Anp-1363Anas platyrhynchos41.564e-24 100
LLPS-Scf-2885Scleropages formosus41.561e-24 103
LLPS-Leo-3196Lepisosteus oculatus40.528e-26 106
LLPS-Pes-1410Pelodiscus sinensis40.41e-24 103
LLPS-Icp-2016Ictalurus punctatus40.41e-2092.0
LLPS-Asm-3742Astyanax mexicanus40.135e-2193.2
LLPS-Aon-3070Aotus nancymaae40.01e-25 106
LLPS-Ict-1413Ictidomys tridecemlineatus39.743e-25 105
LLPS-Gaga-2824Gallus gallus39.741e-24 103
LLPS-Orc-2497Oryctolagus cuniculus39.743e-25 104
LLPS-Meg-1228Meleagris gallopavo39.749e-26 105
LLPS-Ora-0868Ornithorhynchus anatinus39.462e-2296.7
LLPS-Nol-3420Nomascus leucogenys39.071e-24 103
LLPS-Cas-1971Carlito syrichta39.071e-24 103
LLPS-Mam-2242Macaca mulatta39.071e-24 103
LLPS-Caf-3926Canis familiaris39.072e-24 102
LLPS-Cap-1848Cavia porcellus39.077e-25 103
LLPS-Rhb-2215Rhinopithecus bieti39.074e-25 103
LLPS-Man-2057Macaca nemestrina39.071e-24 103
LLPS-Loa-4530Loxodonta africana39.074e-25 103
LLPS-Pat-4601Pan troglodytes39.071e-24 103
LLPS-Fec-3634Felis catus39.079e-25 103
LLPS-Paa-0307Papio anubis39.071e-24 103
LLPS-Mal-3004Mandrillus leucophaeus39.074e-25 103
LLPS-Myl-1286Myotis lucifugus39.076e-25 104
LLPS-Ova-2008Ovis aries39.074e-25 103
LLPS-Ran-0384Rattus norvegicus39.076e-25 104
LLPS-Bot-1659Bos taurus39.079e-25 103
LLPS-Caj-0907Callithrix jacchus39.072e-24 102
LLPS-Gog-4411Gorilla gorilla39.078e-25 103
LLPS-Cea-2243Cercocebus atys39.071e-24 103
LLPS-Sus-1023Sus scrofa39.077e-25 103
LLPS-Mea-1220Mesocricetus auratus39.071e-24 103
LLPS-Maf-2204Macaca fascicularis39.071e-24 103
LLPS-Mum-3517Mus musculus39.079e-25 103
LLPS-Hos-2563Homo sapiens38.416e-24 101
LLPS-Fud-3096Fukomys damarensis38.411e-2399.4
LLPS-Chs-2622Chlorocebus sabaeus38.416e-24 101
LLPS-Gaa-0449Gasterosteus aculeatus38.268e-2295.1
LLPS-Dar-1479Danio rerio37.824e-2193.2
LLPS-Ere-0574Erinaceus europaeus37.54e-1987.0
LLPS-Poa-0758Pongo abelii37.332e-2297.1
LLPS-Chr-1199Chlamydomonas reinhardtii36.052e-0857.0
LLPS-Scm-1201Scophthalmus maximus35.212e-1782.8
LLPS-Tag-2909Taeniopygia guttata35.11e-1577.0
LLPS-Mua-0621Musa acuminata34.418e-0855.1
LLPS-Cus-0391Cucumis sativus34.022e-0959.3
LLPS-Hea-2001Helianthus annuus34.029e-0752.4
LLPS-Mod-1069Monodelphis domestica33.868e-1573.2
LLPS-Cii-1027Ciona intestinalis33.114e-0856.2
LLPS-Amt-0659Amborella trichopoda32.269e-0854.7
LLPS-Pot-0886Populus trichocarpa31.964e-0958.5
LLPS-Bro-2990Brassica oleracea31.912e-1062.4
LLPS-Brr-2322Brassica rapa31.913e-1062.0
LLPS-Met-1403Medicago truncatula31.918e-0957.8
LLPS-Via-1026Vigna angularis31.915e-0856.6
LLPS-Brn-2901Brassica napus31.912e-1062.0
LLPS-Pap-2857Pan paniscus31.825e-0956.6
LLPS-Lep-1298Leersia perrieri31.585e-0650.1
LLPS-Dac-1346Daucus carota31.582e-0754.3
LLPS-Urm-3509Ursus maritimus31.533e-0957.0
LLPS-Dio-3193Dipodomys ordii31.533e-0957.0
LLPS-Org-1313Oryza glaberrima30.999e-0649.3
LLPS-Orr-0475Oryza rufipogon30.999e-0649.3
LLPS-Ors-0579Oryza sativa30.999e-0649.3
LLPS-Orb-1007Oryza barthii30.999e-0649.3
LLPS-Ori-1053Oryza indica30.999e-0649.3
LLPS-Phv-0971Phaseolus vulgaris30.851e-0754.3
LLPS-Art-2534Arabidopsis thaliana30.851e-1063.2
LLPS-Vir-1533Vigna radiata30.851e-0754.7
LLPS-Php-2348Physcomitrella patens30.612e-0959.3
LLPS-Viv-0568Vitis vinifera30.03e-0650.4
LLPS-Prp-0363Prunus persica29.798e-0752.4
LLPS-Mup-1181Mustela putorius furo29.147e-1471.6
LLPS-Arl-0139Arabidopsis lyrata28.729e-0957.8
LLPS-Sem-2207Selaginella moellendorffii26.533e-0753.5