LLPS-Drm-1064
Syf2

▼ OVERVIEW

Status: Unreviewed
Protein Name: Pre-mRNA-splicing factor Syf2
Gene Name: Syf2, CG12343
Ensembl Gene: FBgn0033556
Ensembl Protein: FBpp0087342
Organism: Drosophila melanogaster
Taxa ID: 7227
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Involved in pre-mRNA splicing as component of the spliceosome.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblFBtr0088247FBpp0087342
UniProtQ9V5Q4, SYF2_DROME
GeneBankAE013599, BT022631AAF58745.1, AAY55047.1
RefSeqNM_136773.3NP_610617.1
Entrez36143

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEKTKTAAEK  LAERKARLLD  LHKKRQEART  DNHQEVVAED  ARKKLPKNWE  ARKRQAEWIL  60
61    ADDKARAEAQ  AAGKDYERLK  LLEVSAVDAD  RIEKKKKRKD  NPDLGFSTYE  AQTARQYNRL  120
121   VKSMPARDLE  KYERQKEELG  DAFYGGAHTT  LHSRTKDTPG  AINKMVTDLE  QQIERRKKYS  180
181   RRRIYNDDAD  VDFINERNSK  FNKKLDRFYS  EHTAEIKQNL  ERGTAI  226
Nucleotide CDS Sequence (FASTA)
1     ATGGAAAAGA  CGAAAACGGC  TGCCGAAAAA  TTGGCGGAGC  GCAAGGCGCG  TTTGCTGGAC  60
61    CTACACAAGA  AGCGCCAGGA  GGCGCGTACG  GACAACCACC  AGGAAGTGGT  GGCAGAGGAC  120
121   GCTCGCAAGA  AGCTCCCCAA  GAACTGGGAG  GCTCGCAAGC  GACAGGCGGA  ATGGATACTA  180
181   GCGGACGACA  AGGCGCGAGC  CGAGGCGCAG  GCAGCTGGCA  AGGATTACGA  GCGTTTGAAG  240
241   CTTTTGGAGG  TATCCGCTGT  GGATGCGGAT  CGCATTGAGA  AAAAGAAGAA  GCGTAAAGAC  300
301   AATCCAGATC  TTGGTTTCTC  CACATACGAA  GCTCAAACAG  CTAGACAGTA  CAACCGATTG  360
361   GTCAAGAGTA  TGCCTGCTCG  CGATTTGGAA  AAGTACGAGC  GCCAGAAGGA  GGAACTCGGT  420
421   GACGCCTTCT  ACGGTGGAGC  ACACACCACT  TTGCATTCGA  GGACGAAGGA  CACTCCAGGT  480
481   GCTATTAACA  AAATGGTAAC  AGACCTGGAG  CAGCAGATAG  AGCGCCGCAA  GAAGTACTCT  540
541   CGCAGGAGGA  TCTACAACGA  CGATGCGGAT  GTGGACTTCA  TCAACGAGAG  GAATTCCAAG  600
601   TTCAACAAAA  AGCTGGACCG  CTTCTACAGC  GAGCATACAG  CCGAGATCAA  ACAAAATTTG  660
661   GAGCGGGGAA  CAGCTATT  678

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
mRNA processing
mRNA splicing
Nucleus
Reference proteome
Spliceosome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Catalytic step 2 spliceosome
Cellular Component
Post-mRNA release spliceosomal complex
Cellular Component
Precatalytic spliceosome
Cellular Component
Prp19 complex
Cellular Component
U2-type catalytic step 2 spliceosome
Molecular Function
RNA binding
Biological Process
MRNA splicing, via spliceosome

▼ KEGG


▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
RAINIIDMIST
Physicochemical
AAindex
Function
PIRSF
Localization
COMPARTMENTS

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anp-2496Anas platyrhynchos60.53e-67 213
LLPS-Meg-1509Meleagris gallopavo60.03e-66 210
LLPS-Anc-0383Anolis carolinensis59.52e-68 215
LLPS-Orc-1492Oryctolagus cuniculus59.422e-68 217
LLPS-Ora-3203Ornithorhynchus anatinus59.112e-70 220
LLPS-Caj-1103Callithrix jacchus58.941e-67 215
LLPS-Aon-3026Aotus nancymaae58.941e-67 215
LLPS-Pes-0803Pelodiscus sinensis58.642e-71 225
LLPS-Pap-2075Pan paniscus58.458e-67 213
LLPS-Pat-1212Pan troglodytes58.458e-67 213
LLPS-Hos-3463Homo sapiens58.458e-67 213
LLPS-Nol-0665Nomascus leucogenys58.457e-67 213
LLPS-Caf-1065Canis familiaris58.452e-67 214
LLPS-Gog-0455Gorilla gorilla58.458e-67 213
LLPS-Tut-1467Tursiops truncatus58.452e-66 212
LLPS-Gaga-3103Gallus gallus58.372e-70 222
LLPS-Eqc-1485Equus caballus58.182e-68 217
LLPS-Urm-0572Ursus maritimus57.972e-66 212
LLPS-Xet-0850Xenopus tropicalis57.733e-70 221
LLPS-Myl-1018Myotis lucifugus57.734e-70 221
LLPS-Fec-4325Felis catus57.41e-69 221
LLPS-Fia-3243Ficedula albicollis57.286e-66 211
LLPS-Mea-2934Mesocricetus auratus57.271e-69 220
LLPS-Dio-4006Dipodomys ordii57.275e-69 218
LLPS-Loa-1296Loxodonta africana56.827e-69 218
LLPS-Poa-1321Pongo abelii56.825e-68 216
LLPS-Fud-0349Fukomys damarensis56.821e-68 218
LLPS-Sus-3444Sus scrofa56.821e-68 217
LLPS-Mum-2227Mus musculus56.824e-69 218
LLPS-Aim-2446Ailuropoda melanoleuca56.828e-69 218
LLPS-Mup-1177Mustela putorius furo56.822e-68 217
LLPS-Ran-2846Rattus norvegicus56.824e-69 218
LLPS-Sah-1355Sarcophilus harrisii56.641e-68 218
LLPS-Otg-1596Otolemur garnettii56.522e-70 222
LLPS-Cap-1270Cavia porcellus56.529e-70 220
LLPS-Bot-0723Bos taurus56.366e-68 216
LLPS-Ova-0671Ovis aries56.311e-66 213
LLPS-Orl-3943Oryzias latipes56.021e-65 209
LLPS-Cas-0396Carlito syrichta55.916e-67 213
LLPS-Pof-1009Poecilia formosa55.755e-66 211
LLPS-Leo-0326Lepisosteus oculatus55.669e-69 218
LLPS-Mam-4093Macaca mulatta55.563e-61 199
LLPS-Dar-2391Danio rerio55.451e-70 222
LLPS-Scf-3722Scleropages formosus55.458e-67 213
LLPS-Tar-2861Takifugu rubripes55.268e-66 211
LLPS-Asm-3443Astyanax mexicanus55.21e-67 215
LLPS-Xim-2825Xiphophorus maculatus55.141e-64 207
LLPS-Scm-0051Scophthalmus maximus55.03e-70 221
LLPS-Mod-1178Monodelphis domestica54.752e-68 216
LLPS-Orn-0984Oreochromis niloticus54.31e-65 209
LLPS-Lac-0753Latimeria chalumnae54.32e-65 209
LLPS-Man-3570Macaca nemestrina54.092e-62 201
LLPS-Maf-0220Macaca fascicularis54.092e-62 201
LLPS-Chs-1374Chlorocebus sabaeus54.092e-62 201
LLPS-Paa-1933Papio anubis54.092e-62 201
LLPS-Icp-3221Ictalurus punctatus53.783e-66 211
LLPS-Rhb-0599Rhinopithecus bieti53.645e-64 206
LLPS-Gaa-1286Gasterosteus aculeatus53.335e-65 208
LLPS-Ten-0226Tetraodon nigroviridis53.184e-64 205
LLPS-Cea-2510Cercocebus atys53.043e-62 201
LLPS-Mal-2337Mandrillus leucophaeus53.043e-62 201
LLPS-Ict-3579Ictidomys tridecemlineatus51.024e-31 117
LLPS-Cis-0934Ciona savignyi50.243e-58 190
LLPS-Tag-2256Taeniopygia guttata50.09e-1471.2
LLPS-Cii-2094Ciona intestinalis49.534e-58 190
LLPS-Usm-0934Ustilago maydis46.482e-1165.9
LLPS-Cae-1568Caenorhabditis elegans46.335e-47 161
LLPS-Zyt-0972Zymoseptoria tritici44.931e-1063.5
LLPS-Ved-1358Verticillium dahliae43.684e-1470.9
LLPS-Hea-2201Helianthus annuus43.04e-1575.5
LLPS-Chc-1205Chondrus crispus39.533e-0855.5
LLPS-Dos-1477Dothistroma septosporum39.084e-1268.2
LLPS-Gas-0988Galdieria sulphuraria38.066e-1267.4
LLPS-Osl-0863Ostreococcus lucimarinus36.092e-1164.7
LLPS-Asf-0350Aspergillus flavus35.43e-1679.7
LLPS-Aso-1336Aspergillus oryzae35.43e-1679.7
LLPS-Asn-0835Aspergillus nidulans35.191e-1577.8
LLPS-Cog-0537Colletotrichum gloeosporioides34.973e-1782.0
LLPS-Yal-1594Yarrowia lipolytica34.435e-1163.2
LLPS-Trr-0415Trichoderma reesei34.366e-1678.6
LLPS-Blg-1194Blumeria graminis34.255e-1370.1
LLPS-Ast-1124Aspergillus terreus34.163e-1268.2
LLPS-Asni-1579Aspergillus niger34.162e-1166.2
LLPS-Abg-0214Absidia glauca34.151e-1577.8
LLPS-Coo-0768Colletotrichum orbiculare33.946e-1678.6
LLPS-Mel-0713Melampsora laricipopulina33.771e-1473.9
LLPS-Trv-1183Trichoderma virens33.745e-1575.9
LLPS-Nef-1063Neosartorya fischeri33.543e-1576.6
LLPS-Coc-0915Corchorus capsularis33.493e-1988.6
LLPS-Pot-1856Populus trichocarpa33.338e-1472.8
LLPS-Cogr-1519Colletotrichum graminicola33.331e-1577.8
LLPS-Thc-0529Theobroma cacao33.333e-2090.9
LLPS-Cus-0507Cucumis sativus33.333e-1885.1
LLPS-Fus-0365Fusarium solani33.132e-1679.7
LLPS-Fuv-1576Fusarium verticillioides33.133e-1679.0
LLPS-Dac-0305Daucus carota33.124e-1473.6
LLPS-Spr-0660Sporisorium reilianum33.117e-1164.7
LLPS-Gor-2485Gossypium raimondii33.043e-1885.1
LLPS-Asfu-1117Aspergillus fumigatus32.922e-1474.3
LLPS-Prp-1199Prunus persica32.882e-1885.9
LLPS-Glm-1665Glycine max32.884e-1473.6
LLPS-Tra-2700Triticum aestivum32.883e-1988.6
LLPS-Sem-0115Selaginella moellendorffii32.751e-2298.2
LLPS-Phn-0517Phaeosphaeria nodorum32.731e-1268.9
LLPS-Scc-0902Schizosaccharomyces cryophilus32.484e-1884.0
LLPS-Mae-1083Manihot esculenta32.424e-1062.4
LLPS-Sob-0359Sorghum bicolor32.423e-2091.7
LLPS-Zem-0899Zea mays32.426e-2090.5
LLPS-Met-1639Medicago truncatula32.424e-1885.1
LLPS-Asc-1209Aspergillus clavatus32.415e-0959.3
LLPS-Tum-0961Tuber melanosporum32.052e-1268.6
LLPS-Sei-2407Setaria italica31.963e-1988.6
LLPS-Brd-0704Brachypodium distachyon31.961e-1886.7
LLPS-Fuo-0366Fusarium oxysporum31.93e-1679.0
LLPS-Orp-1277Oryza punctata31.866e-1782.0
LLPS-Lem-0912Leptosphaeria maculans31.716e-0958.9
LLPS-Nec-1595Neurospora crassa31.675e-1884.7
LLPS-Phv-1715Phaseolus vulgaris31.519e-1370.1
LLPS-Orbr-0446Oryza brachyantha31.511e-1887.0
LLPS-Ors-1470Oryza sativa31.517e-1987.4
LLPS-Orr-0350Oryza rufipogon31.517e-1987.4
LLPS-Orni-0535Oryza nivara31.517e-1987.4
LLPS-Ori-1000Oryza indica31.514e-1987.8
LLPS-Lep-1878Leersia perrieri31.512e-1887.0
LLPS-Orgl-0040Oryza glumaepatula31.517e-1987.4
LLPS-Amt-0549Amborella trichopoda31.468e-1883.2
LLPS-Org-0112Oryza glaberrima31.053e-1885.9
LLPS-Orb-0743Oryza barthii31.053e-1885.9
LLPS-Sol-0737Solanum lycopersicum31.035e-1884.7
LLPS-Nia-2426Nicotiana attenuata31.02e-1782.8
LLPS-Beb-0944Beauveria bassiana30.912e-1474.3
LLPS-Viv-1175Vitis vinifera30.873e-1885.5
LLPS-Via-0426Vigna angularis30.875e-1370.5
LLPS-Php-0336Physcomitrella patens30.818e-1781.3
LLPS-Mao-1233Magnaporthe oryzae30.672e-1371.2
LLPS-Vir-2200Vigna radiata30.672e-1371.6
LLPS-Scp-0677Schizosaccharomyces pombe30.632e-1576.3
LLPS-Sot-1553Solanum tuberosum30.572e-1782.8
LLPS-Mua-1277Musa acuminata29.918e-1781.6
LLPS-Brr-1627Brassica rapa29.824e-1576.3
LLPS-Scj-0863Schizosaccharomyces japonicus29.361e-1680.1
LLPS-Bro-1718Brassica oleracea29.227e-1575.5
LLPS-Brn-0080Brassica napus29.227e-1575.5
LLPS-Put-0175Puccinia triticina29.143e-1164.3
LLPS-Art-0309Arabidopsis thaliana29.131e-1474.7
LLPS-Gag-0889Gaeumannomyces graminis28.852e-1577.8
LLPS-Pytr-1542Pyrenophora triticirepentis28.753e-0959.7
LLPS-Pyt-1256Pyrenophora teres28.754e-0959.7
LLPS-Arl-1050Arabidopsis lyrata28.71e-1474.7
LLPS-Crn-0059Cryptococcus neoformans28.467e-1370.5
LLPS-Pug-0695Puccinia graminis28.222e-1268.2
LLPS-Map-0909Magnaporthe poae27.787e-1678.6