LLPS-Drm-0599
Son
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Uncharacterized protein, isoform A |
| Gene Name: | Son, cg8273, Dmel\CG8273, CG8273, Dmel_CG8273 |
| Ensembl Gene: | FBgn0037716 |
| Ensembl Protein: | FBpp0081550 |
| Organism: | Drosophila melanogaster |
| Taxa ID: | 7227 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | FBtr0082072 | FBpp0081550 |
| Ensembl | FBtr0334655 | FBpp0306717 |
| UniProt | Q9VHB0, Q9VHB0_DROME | |
| GeneBank | AE014297 | AAF54409.1, AGB95808.1 |
| RefSeq | NM_001275497.1, NM_141657.4 | NP_001262426.1, NP_649914.1 |
| Entrez | 41159 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTENTEKGAS VETPQVAGSQ TNPPVQEPLA LTKIPPIKVK SERPDAEVEA KLRAMNAKIK 60 61 AEMVTLMRRS NSNELGNNDE SGESESSASA DDKKNIKPVK SSNEILAELF GVFNAAPPEE 120 121 LLDDNLFKKK KKVKKEKKDK KAKKKKTTKS DGECSDSEAE GKHKHKRKKH KHKDIRVKDK 180 181 EKDRDRDKSK EKDRDRVTDK SKEKDRDRDR DRDKSKDKFT AAQAPSEKEK EKSESRKRSA 240 241 VEPSSHSEKR ERHEREKHRD WEREREREKE HERERVRSNN SFYNGQREAD RLKGSESAST 300 301 KSRQEQDLSD ISLSDEESYL REKASNGRRR AHNSFYDEKE ELSVSPKRNV RESNTRRNRK 360 361 SRSRSRDLGI DKKRLLEIAR RNAINMFKQG TMPGVANMTA EVKDKVLVKM RYGGRTIQDL 420 421 TDFCKKISNG DGLSDLSSEE ESDVDKNGNA KVFHHPFQLK EREPIVMHIR NSTALVPAPP 480 481 RLDEQTKAIT MQFPVSSGQT HRNNEVWVPV DPKDSLVPLP SLPPAKQATN MFKETPKNVF 540 541 AKSIPLQEQQ EPAFKPLGGA VVVPPLAATQ LPTVPQSVPP TVPKEFAPPA VPFVPEVPIP 600 601 STSPVTPMQS ASIFPDVTPP SMDVSSIITQ RLSAIRRLQE NPADSEALKM MYTAQRNMSS 660 661 WANSKHLPGQ FTGSTGAQVM KAHELNSGPQ LWVRKDQMTS TKPVTGGMGM ALLQKMGWKP 720 721 GEGLGRCKTG SLQPLLLDVK LDKRGLVSRD DLRPPQMRAP AAQRRNKNMA GPIGAGPCPA 780 781 VQGAGPGPLA STPLVTQDKH PVCVLNELTS KNKWMPPQYK LRQDIGPAHN RSFLFSVEIN 840 841 GQTFTPDRGS NNKKEAKLNA AALCLRSLGI LPPS 874 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACGGAGA ACACAGAGAA AGGGGCGAGC GTAGAAACGC CTCAAGTGGC GGGGTCTCAG 60 61 ACAAATCCTC CGGTTCAGGA GCCACTTGCA CTGACCAAGA TTCCGCCAAT TAAGGTAAAG 120 121 AGCGAACGAC CGGACGCAGA GGTGGAGGCC AAACTCCGGG CCATGAATGC CAAGATCAAG 180 181 GCGGAGATGG TGACTTTGAT GCGGAGGAGC AACAGCAATG AACTGGGCAA CAATGACGAG 240 241 TCGGGGGAGA GCGAGAGCTC CGCGTCGGCG GACGACAAGA AGAACATTAA GCCTGTAAAG 300 301 TCCTCGAACG AGATCCTTGC CGAGCTGTTC GGCGTATTCA ATGCCGCTCC ACCAGAGGAA 360 361 CTTCTAGACG ACAATCTGTT CAAGAAAAAG AAAAAGGTGA AAAAGGAGAA GAAGGATAAG 420 421 AAGGCCAAGA AAAAGAAGAC GACCAAGTCA GATGGCGAAT GCAGCGACTC GGAGGCGGAA 480 481 GGCAAGCACA AGCATAAACG TAAGAAGCAC AAACATAAAG ACATCAGAGT CAAAGACAAG 540 541 GAGAAGGATC GGGACCGGGA CAAATCTAAG GAGAAAGATC GGGACCGCGT TACGGACAAA 600 601 TCAAAGGAGA AGGATCGGGA CAGGGACAGG GATAGGGACA AATCCAAAGA TAAGTTTACG 660 661 GCAGCACAAG CTCCCTCCGA GAAGGAGAAA GAAAAGTCTG AGAGCCGGAA GCGCAGCGCT 720 721 GTGGAGCCTT CCAGTCATTC CGAAAAGCGC GAACGACATG AAAGGGAGAA GCATCGCGAC 780 781 TGGGAACGAG AAAGGGAACG GGAAAAGGAG CATGAAAGGG AACGCGTCCG CTCCAACAAT 840 841 AGCTTTTACA ACGGGCAACG TGAAGCGGAT CGCTTGAAAG GATCTGAATC AGCGAGCACA 900 901 AAGTCACGGC AGGAACAAGA TCTCTCCGAT ATCTCGCTCT CCGATGAGGA GTCGTACCTC 960 961 CGGGAGAAGG CTTCCAACGG CCGTAGACGG GCGCACAACA GCTTTTATGA TGAAAAGGAG 1020 1021 GAATTGTCGG TTTCACCCAA GCGTAACGTG CGCGAATCCA ACACCAGGAG AAACCGAAAG 1080 1081 TCAAGATCTC GCTCGCGTGA CCTCGGCATA GACAAAAAGC GCTTGCTCGA GATTGCGCGA 1140 1141 CGAAATGCCA TTAACATGTT CAAACAGGGA ACTATGCCCG GTGTGGCTAA CATGACTGCA 1200 1201 GAGGTCAAGG ACAAGGTTCT CGTCAAGATG CGCTACGGAG GTCGCACTAT TCAAGATCTT 1260 1261 ACCGACTTCT GCAAAAAAAT CTCCAACGGC GACGGCCTGT CAGATCTGAG TTCAGAAGAG 1320 1321 GAGTCCGATG TGGACAAGAA TGGTAATGCG AAGGTCTTCC ATCATCCCTT TCAGCTGAAG 1380 1381 GAGCGCGAGC CAATTGTGAT GCATATACGA AACTCAACGG CGCTGGTTCC AGCACCACCT 1440 1441 CGACTGGACG AGCAAACAAA GGCCATAACC ATGCAGTTCC CGGTGTCGTC GGGTCAGACC 1500 1501 CATCGCAACA ATGAGGTGTG GGTGCCGGTG GATCCTAAGG ACTCGCTAGT GCCGTTGCCC 1560 1561 TCCCTACCGC CAGCAAAACA GGCCACCAAT ATGTTTAAGG AAACGCCGAA GAACGTGTTC 1620 1621 GCGAAGTCGA TACCCTTGCA GGAGCAGCAG GAACCCGCCT TTAAGCCACT GGGAGGAGCA 1680 1681 GTCGTAGTCC CGCCCTTAGC CGCCACTCAA TTACCCACTG TTCCTCAATC CGTCCCGCCA 1740 1741 ACCGTTCCCA AAGAGTTTGC CCCTCCGGCT GTTCCCTTCG TTCCCGAGGT GCCCATCCCG 1800 1801 TCAACGTCAC CCGTAACACC GATGCAAAGT GCTTCCATTT TTCCCGATGT TACGCCGCCT 1860 1861 TCCATGGACG TGTCCAGCAT AATCACCCAG CGTCTTAGTG CCATTCGACG CCTGCAGGAG 1920 1921 AATCCGGCCG ACTCTGAGGC CCTAAAAATG ATGTACACTG CGCAACGCAA CATGTCATCG 1980 1981 TGGGCCAACT CAAAGCATCT GCCCGGTCAG TTCACGGGAA GCACGGGTGC CCAAGTGATG 2040 2041 AAGGCACATG AGCTGAACAG CGGTCCGCAG CTGTGGGTGC GCAAAGACCA AATGACCTCC 2100 2101 ACCAAACCGG TGACTGGGGG CATGGGCATG GCGCTCCTGC AAAAGATGGG CTGGAAACCG 2160 2161 GGCGAGGGAC TGGGCAGATG TAAAACTGGA TCATTGCAAC CACTTTTGCT GGACGTCAAA 2220 2221 TTGGACAAGC GTGGCCTGGT GTCGCGCGAT GACTTAAGGC CACCGCAAAT GCGTGCGCCG 2280 2281 GCTGCCCAGC GAAGAAATAA AAACATGGCG GGACCAATTG GAGCTGGCCC CTGTCCAGCA 2340 2341 GTTCAGGGTG CGGGACCTGG ACCGTTGGCG TCCACGCCGC TGGTCACCCA GGATAAGCAT 2400 2401 CCCGTGTGTG TGCTCAACGA ACTGACCTCG AAGAACAAGT GGATGCCGCC GCAGTATAAG 2460 2461 CTACGTCAGG ATATCGGGCC CGCTCACAAC CGTTCCTTTC TCTTTTCGGT CGAGATTAAC 2520 2521 GGACAGACCT TTACGCCGGA TCGAGGAAGC AACAACAAGA AGGAGGCGAA ACTCAATGCG 2580 2581 GCCGCCTTAT GTCTGCGATC TTTAGGCATT CTTCCGCCCA GC 2622 |
▼ ANNOTATION
| Physicochemical | ||||
| AAindex | ||||
| Function | ||||
| ENPD | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | ||||
| Element | ||||
| microRNA.org | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Anc-0829 | Anolis carolinensis | 48.0 | 3e-13 | 77.4 |
| LLPS-Gaa-0807 | Gasterosteus aculeatus | 47.06 | 3e-16 | 86.3 |
| LLPS-Anp-1963 | Anas platyrhynchos | 44.44 | 1e-15 | 84.7 |
| LLPS-Ora-1670 | Ornithorhynchus anatinus | 44.0 | 1e-11 | 72.4 |
| LLPS-Bot-4480 | Bos taurus | 43.59 | 3e-12 | 75.5 |
| LLPS-Leo-0385 | Lepisosteus oculatus | 41.67 | 1e-10 | 69.7 |
| LLPS-Lac-1733 | Latimeria chalumnae | 40.67 | 1e-51 | 193 |
| LLPS-Xet-2195 | Xenopus tropicalis | 40.42 | 2e-48 | 182 |
| LLPS-Ova-0786 | Ovis aries | 40.08 | 5e-46 | 184 |
| LLPS-Xim-3192 | Xiphophorus maculatus | 40.07 | 3e-47 | 186 |
| LLPS-Scm-2779 | Scophthalmus maximus | 40.0 | 4e-47 | 186 |
| LLPS-Fia-1658 | Ficedula albicollis | 39.85 | 2e-50 | 189 |
| LLPS-Pes-0690 | Pelodiscus sinensis | 39.77 | 8e-49 | 184 |
| LLPS-Gaga-1953 | Gallus gallus | 39.77 | 1e-48 | 192 |
| LLPS-Chs-3690 | Chlorocebus sabaeus | 39.68 | 3e-46 | 184 |
| LLPS-Mum-2247 | Mus musculus | 39.68 | 9e-46 | 183 |
| LLPS-Caj-0177 | Callithrix jacchus | 39.68 | 1e-45 | 182 |
| LLPS-Fud-2367 | Fukomys damarensis | 39.68 | 1e-45 | 182 |
| LLPS-Mup-2883 | Mustela putorius furo | 39.68 | 1e-45 | 182 |
| LLPS-Eqc-0595 | Equus caballus | 39.68 | 1e-45 | 182 |
| LLPS-Cap-2753 | Cavia porcellus | 39.68 | 8e-46 | 183 |
| LLPS-Poa-1898 | Pongo abelii | 39.68 | 1e-45 | 182 |
| LLPS-Mam-0162 | Macaca mulatta | 39.68 | 3e-46 | 184 |
| LLPS-Pof-2065 | Poecilia formosa | 39.62 | 9e-47 | 179 |
| LLPS-Myl-1549 | Myotis lucifugus | 39.21 | 2e-43 | 175 |
| LLPS-Cas-2999 | Carlito syrichta | 39.21 | 2e-43 | 176 |
| LLPS-Tar-0317 | Takifugu rubripes | 38.83 | 3e-46 | 183 |
| LLPS-Mea-2355 | Mesocricetus auratus | 38.77 | 2e-45 | 174 |
| LLPS-Maf-3692 | Macaca fascicularis | 38.77 | 2e-43 | 176 |
| LLPS-Cea-0482 | Cercocebus atys | 38.77 | 2e-43 | 176 |
| LLPS-Aon-0507 | Aotus nancymaae | 38.77 | 2e-43 | 176 |
| LLPS-Sus-1664 | Sus scrofa | 38.77 | 2e-43 | 176 |
| LLPS-Gog-2995 | Gorilla gorilla | 38.77 | 2e-43 | 175 |
| LLPS-Dio-1123 | Dipodomys ordii | 38.77 | 2e-45 | 174 |
| LLPS-Ran-1226 | Rattus norvegicus | 38.77 | 2e-43 | 176 |
| LLPS-Aim-2471 | Ailuropoda melanoleuca | 38.77 | 2e-43 | 176 |
| LLPS-Paa-3509 | Papio anubis | 38.77 | 2e-43 | 176 |
| LLPS-Mal-2880 | Mandrillus leucophaeus | 38.77 | 2e-43 | 176 |
| LLPS-Mod-0690 | Monodelphis domestica | 38.77 | 2e-43 | 176 |
| LLPS-Fec-3293 | Felis catus | 38.77 | 2e-45 | 174 |
| LLPS-Urm-1464 | Ursus maritimus | 38.77 | 2e-43 | 176 |
| LLPS-Pat-3135 | Pan troglodytes | 38.77 | 2e-43 | 176 |
| LLPS-Hos-2209 | Homo sapiens | 38.77 | 9e-43 | 173 |
| LLPS-Loa-3905 | Loxodonta africana | 38.77 | 2e-43 | 176 |
| LLPS-Man-3353 | Macaca nemestrina | 38.77 | 2e-43 | 176 |
| LLPS-Rhb-3062 | Rhinopithecus bieti | 38.77 | 2e-45 | 174 |
| LLPS-Orc-1698 | Oryctolagus cuniculus | 38.77 | 2e-43 | 176 |
| LLPS-Caf-3400 | Canis familiaris | 38.77 | 2e-43 | 176 |
| LLPS-Nol-3923 | Nomascus leucogenys | 38.77 | 1e-43 | 176 |
| LLPS-Cii-0421 | Ciona intestinalis | 38.74 | 1e-39 | 157 |
| LLPS-Orn-2114 | Oreochromis niloticus | 38.63 | 3e-46 | 177 |
| LLPS-Icp-1018 | Ictalurus punctatus | 37.92 | 2e-43 | 174 |
| LLPS-Scf-2316 | Scleropages formosus | 37.86 | 5e-43 | 174 |
| LLPS-Meg-0196 | Meleagris gallopavo | 37.36 | 2e-43 | 169 |
| LLPS-Ten-2096 | Tetraodon nigroviridis | 37.28 | 7e-44 | 170 |
| LLPS-Asm-0481 | Astyanax mexicanus | 37.04 | 1e-43 | 176 |
| LLPS-Sah-3221 | Sarcophilus harrisii | 36.04 | 1e-08 | 63.9 |
| LLPS-Cae-1430 | Caenorhabditis elegans | 35.41 | 4e-38 | 157 |
| LLPS-Dar-2491 | Danio rerio | 31.11 | 3e-13 | 72.4 |
| LLPS-Pap-1074 | Pan paniscus | 29.27 | 7e-08 | 57.0 |
| LLPS-Orl-2407 | Oryzias latipes | 29.02 | 9e-37 | 153 |